Pathogenesis of Gout, Allopurinol Dosing, the Hypouricemic Effect of Milk, and the Mortality Impact of Gout

Session Type: ACR Concurrent Abstract Sessions
Tuesday, October 20, 2009: 4:30 PM-6:00 PM
Auditorium (Pennsylvania Convention Center)
Organizers: Nicola Dalbeth, FRACP, MD, University of Auckland and M. A. Becker, MD, University of Chicago
Moderators: Dorian O. Haskard, DM, FRCP, Imperial College and Peter A. Simkin, M.D., University of Washington
Papers:
4:30 PM
Severity of Gout and Mortality
Fernando Perez-Ruiz, M.D., PhD, Hospital De Cruces; Lorea Martinez-Indart, MSc, Hospital de Cruces; Loreto Carmona, MD, PhD, Fundación Española Reumatol.; Ana M. Herrero-Beites, MD, Hospital de Gorliz; Jose I. Pijoan, M.D., PhD, Hospital de Cruces
4:45 PM
The Acute Effect of Skim Milk On Serum Urate Concentrations: A Randomized Controlled Cross-Over Trial
Nicola Dalbeth, FRACP, University of Auckland; Sumwai Wong, University of Auckland; Greg Gamble, University of Auckland; Anne Horne, University of Auckland; Barbara Mason, University of Auckland; Lynette Fairbanks, Guy's Hospital; Fiona M. McQueen, University of Auckland; Jillian Cornish, University of Auckland; Ian R. Reid, University of Auckland; Kate Palmano, Fonterra Research Centre
5:00 PM
Cellular Characterization of the Gouty Tophus: a Quantitative Analysis
Nicola Dalbeth, FRACP, MD, University of Auckland; Bregina Pool, University of Auckland; Greg Gamble, University of Auckland; Timothy Smith, University of Auckland; Karen E. Callon, University of Auckland; Fiona M. McQueen, University of Auckland; Jillian Cornish, University of Auckland
5:15 PM
Intracellular Calcium Oscillations in Articular Chondrocytes Induced by Basic Calcium Phosphate Crystals Lead to Cartilage Degradation
Christelle Nguyen, MD, INSERM UMR-S 606, Paris-Diderot University, Lariboisière Hospital; Hang-Korng Ea, MD, PhD, INSERM UMR-S 606, Paris-Diderot University, Lariboisière Hospital; Christian Bordat, PhD, INRA UR 909, MIMA 2 Plateform; Michèle Lieberherr, PhD, INSERM U567, CNRS UMR 8104, Paris-Descartes University, Cochin Institute; Frédéric Lioté, MD, PhD, INSERM UMR-S 606, Paris-Diderot University, Lariboisière Hospital
5:30 PM
Increasing Allopurinol Dose Above the Recommended Range Is Effective and Safe in Chronic Gout, Including in Those with Renal Impairment – a Pilot Study
Lisa Stamp, FRACP, PhD, University of Otago; J.L. O'Donnell, MB, Canterbury Health Laboratories; M. Zhang, PhD, Christchurch Hospital; C. Frampton, PhD, University of Otago; M. Barclay, FRACP, Christchurch Hospital; PT Chapman, FRACP, Christchurch Hospital
5:45 PM
Dynamics of Transcription Regulation of Urate Crystal Inflammation in a Synovium-Like Tissue
Christian T. Mayer, BS, University of Pennsylvania; John W. Tobias, PhD, University of Pennsylvania; Joseph P. Menetski, PhD, Merck Research Labs; H. R. Schumacher Jr., MD, U Penn & VA Med Ctr; Frank Pessler, MD, PhD, Technical University Dresden Children's Hospital
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