Rheumatoid Arthritis Therapy: Biologic Therapy

Session Type: ACR Concurrent Abstract Sessions
Sunday, October 18, 2009: 4:30 PM-6:00 PM
103 A (Pennsylvania Convention Center)
Organizers: Eric M. Ruderman, MD, Northwestern University Feinberg School of Medicine and Daniel Aletaha, MD, Medical University of Vienna
Moderators: Vibeke Strand, M.D., Stanford University and Richard W. Martin, M.D., MA, Michigan State University College of Human Medicine
Papers:
4:30 PM
635
Smoking Is Associated with Non-Response to Methotrexate and to Anti-TNF Treatment in Patients with Rheumatoid Arthritis. Results From the Swedish EIRA Study
Saedis Saevarsdottir, MD, PhD, Karolinska University Hospital; Sara Wedrén, MD, PhD, Karolinska Institutet; Maria Seddighzadeh, PhD, Karolinska Institutet; Johan Askling, MD, PhD, Karolinska University Hospital; Leonid Padyukov, MD, PhD, Karolinska Institutet; Lars Alfredsson, PhD, Karolinska Institutet; Lars Klareskog, MD, PhD, Karolinska University Hospital
4:45 PM
636
Rituximab in Combination with Methotrexate (MTX) Significantly Inhibits Joint Damage and Improves Clinical Outcomes in Patients with Early Active RA Who Are Naïve to MTX: A Randomized Active Comparator Placebo-Controlled Trial (IMAGE)
Paul P. Tak, MD, PhD, Academic Medical Center/ University of Amsterdam; William F. C. Rigby, MD, Dartmouth Hitchcock Medical Center; Andrea Rubbert-Roth, M, University of Cologne; Charles G. Peterfy, MD, PhD, Synarc Inc.; Ronald F. van Vollenhoven, MD, PhD, The Karolinska Institute; William Stohl, MD, PhD, Univ Southern California; Eva Hessey, BSc, MSc, Roche Products Ltd; Annie C. Chen, MD, MPH, Genentech, Inc; Helen Tyrrell, BSc, Roche Products Ltd; Tim M. Shaw, Roche Products Ltd
5:00 PM
637
LITHE: Tocilizumab Inhibits Radiographic Progression and Improves Physical Function in Rheumatoid Arthritis (RA) Patients (Pts) at 2 Yrs with Increasing Clinical Efficacy Over Time
Roy Fleischmann, MD, Metroplex Clinical Research Center; R. Burgos-Vargas, Hospital General de México; P. Ambs, Roche; E. Alecock, Roche; J. Kremer, MD, Albany Medical College
5:15 PM
638
Disease Remission Is Achieved within Two Years in Over Half of Methotrexate Naive Patients with Early Erosive Rheumatoid Arthritis (RA) Treated with Abatacept Plus MTX: Results From the AGREE Trial
R. Westhovens, MD, PhD, UZ Gasthuisberg, KU Leuven; M. Robles, M.D., Centrol Medico Toluca; S. Nayiager, St Augustine's Hospital; J. Wollenhaupt, MD, Klinikum Eilbek; P. Durez, M, PhD, Univ Catholique de Louvain; J. Gómez-Reino, M, PhD, Hospital Clinico Univ De Santiago; W. Grassi, M, PhD, Univ Politecnica delle Marche; B. Haraoui, MD, Institut de Rhumatolgie de Montreal; W. Shergy, MD, Univ of Alabama; SH Park, MD, PhD, Kangnam St Mary's Hosp; H. Genant, MD, University of California; C. Peterfy, MD, PhD, SYNARC, Inc; J.-C. Becker, MD, Bristol-Myers Squibb; A. Covucci, Bristol-Myers Squibb; R. Helfrick, Bristol-Myers Squibb; J. Bathon, MD, Johns Hopkins Univ Sch of Med
5:30 PM
639
Reduced Radiographic Progression in Patients with Early Rheumatoid Arthritis (RA) Treated with Abatacept + Methotrexate Compared to Methotrexate Alone: 24 Month Outcomes
J. Bathon, MD, Johns Hopkins Univ Sch of Med; H. Genant, MD, University of California; S. Nayiager, St Augustine's Hospital; J. Wollenhaupt, MD, Klinikum Eilbek; P. Durez, M, PhD, Univ Catholique de Louvain; J. Gómez-Reino, M, PhD, Hospital Clinico Univ De Santiago; W. Grassi, M, PhD, Univ Politecnica delle Marche; B. Haraoui, MD, Institut de Rhumatolgie de Montreal; W. Shergy, MD, Univ of Alabama; SH Park, MD, PhD, Kangnam St Mary's Hosp; M. Robles, M, Centrol Medico Toluca; C. Peterfy, MD, PhD, SYNARC, Inc; J.-C. Becker, MD, Bristol-Myers Squibb; A. Covucci, Bristol-Myers Squibb; R. Helfrick, Bristol-Myers Squibb; R. Westhovens, MD, PhD, UZ Gasthuisberg, KU Leuven
5:45 PM
640
Golimumab and Radiographic Progression in Rheumatoid Arthritis: Results of GO-BEFORE and GO-FORWARD Studies
P. Emery, FRCP, MA, MD, Univ Leeds; R. Fleischmann, MD, U of Texas Southwest Med Center; Désirée M.F.M. van der Heijde, MD, PhD, Leiden University Medical Center; Edward C. Keystone, M.D., FRCP, (C), Professor of Medicine/University of Toronto; M. C. Genovese, MD, Stanford University; P. G. Conaghan, M.D., PhD, U of Leeds; E. C. Hsia, MD, Centocor R&D, Inc/U of Penn School of Med; W. Xu, PhD, Centocor R&D, Inc; A. Baratelle, BSRT, Centocor R&D; A. Beutler, MD, Centocor R&D, Inc; M. U. Rahman, MD, PhD, Centocor R&D, Inc/U of Penn School of Med
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