Pathogenesis of the Antiphospholipid Syndrome

Session Type: ACR Concurrent Abstract Sessions
Wednesday, October 21, 2009: 11:00 AM-12:30 PM
104 A (Pennsylvania Convention Center)
Organizers: Pojen P. Chen, PhD, UCLA Schl of Medicine and Silvia S. Pierangeli, PhD, University of Texas Medical Branch
Moderators: Joyce Rauch, PhD, McGill University and Tatsuya Atsumi, MD, Hokkaido University Graduate School of Medicine
Papers:
11:00 AM
Lupus Susceptible Gene Polymorphisms in Patients with Antiphospholipid Syndrome
Tetsuya Horita, MD, PhD, Hokkaido University Graduate School of Medicine; Hisako Nakagawa, MS, Hokkaido University Graduate School of Medicine; Kenji Oku, MD, PhD, Hokkaido University Graduate School of Medicine; Hiroshi Kataoka, MD, PhD, Hokkaido University Graduate School of Medicine; Shinsuke Yasuda, MD, PhD, Hokkaido University Graduate School of Medicine; Tatsuya Atsumi, MD, PhD, Hokkaido University Graduate School of Medicine; Takao Koike, MD, PhD, Hokkaido University Graduate School of Medicine
11:15 AM
Up-Regulated Expression of Phospholipid Scramblase 1 On Monocytes in Patients with Antiphospholipid Syndrome
Olga Amengual, MD, PhD, Hokkaido University Graduate School of Medicine; Tatsuya Atsumi, MD, PhD, Hokkaido University Graduate School of Medicine; Eriko Suzuki, DDS, Hokkaido University Graduate School of Medicine; Kenji Oku, MD, PhD, Hokkaido University Graduate School of Medicine; Toko Hashimoto, MD, PhD, Hokkaido University Graduate School of Medicine; Masaru Kato, MD, Hokkaido University Graduate School of Medicine; Kotaro Otomo, MD, Hokkaido University Graduate School of Medicine; Yuichiro Fujieda, MD, Hokkaido University Graduate School of Medicine; Hiroshi Kataoka, MD, PhD, Hokkaido University Graduate School of Medicine; Tetsuya Horita, MD, PhD, Hokkaido University Graduate School of Medicine; Shinsuke Yasuda, MD, PhD, Hokkaido University Graduate School of Medicine; Takao Koike, MD, PhD, Hokkaido University Graduate School of Medicine
11:30 AM
Interaction Between Nicked β2-Glycoprotein I and Angiostatin 4.5; Novel Role of Nicked β2-Glycoprotein I in Angiogenesis in Vitro and In Vivo
Hisako Nakagawa, BA, Hokkaido University Graduate School of Medicine; Shinsuke Yasuda, MD, PhD, Hokkaido University Graduate School of Medicine; Eiji Matsuura, PhD, Okayama University Graduate School of Medicine, Denstry, and Pharmaceutical Sciences; Kazuko Kobayashi, PhD, Okayama University Graduate School of Medicine, Denstry, and Pharmaceutical Sciences; Masahiro Ieko, MD, PhD, School of Dentistry, Health Sciences University of Hokkaido; Hiroshi Kataoka, MD, PhD, Hokkaido University Graduate School of Medicine; Tetsuya Horita, MD, PhD, Hokkaido University Graduate School of Medicine; Tatsuya Atsumi, MD, PhD, Hokkaido University Graduate School of Medicine; Takao Koike, MD, PhD, Hokkaido University Graduate School of Medicine
11:45 AM
Autoantibodies to Heat Shock Protein 60 Are Associated with Arterial Vascular Events in Patients with Anti-Phospholipid Antibodies
Mélanie Dieudé, PhD, McGill University; José A. Correa, PhD, McGill University; Carolyn Neville, BA, RN, McGill University; Christian A. Pineau, MD, McGill University; Jerrold S. Levine, MD, University of Illinois at Chicago; Rebecca Subang, McGill University; C. Landolt-Marticorena, M, University of Toronto; Jiandong Su, BSc, MB, University of Toronto; Jeannine Kassis, MD, Université de Montréal; Susan Solymoss, MD, McGill University; Paul. R. Fortin, MD, University of Toronto; Joyce Rauch, PhD, McGill University
12:00 PM
ß2 Glycoprotein I (ß2GPI) Binds Platelet Factor 4 (PF4): Implications for the Pathogenesis of Antiphospholipid Syndrome
MP Sikara, BSc, School of Medicine,National University of Athens; J G. Routsias, M, PhD, School of Medicine, National University of Athens; M. Samiotaki, PhD, Al. Fleming; G. Panayotou, PhD, Al. Fleming; HM Moutsopoulos, FACP, FRCP, MD, School of Medicine,National University of Athens; P G. Vlachoyiannopoulos, MD, School of Medicine, National University of Athens
12:15 PM
A C5a Receptor Antagonist Ameliorates In Vivo Effects of Antiphospholipid Antibodies
Ana Laura Carrera-Marin, MS, University of Texas Medical Branch; Zurina Romay-Penabad, PhD, University of Texas Medical Branch; HongChang Qu, Univeristy of Pennsylvania; Elizabeth Papalardo, BS, University of Texas Medical Branch; John Lambris, PhD, Univeristy of Pennsylvania; Elba Reyes-Maldonado, PhD, Instituto Politecnico Nacional/ ENCB; Ethel Garcia-Latorre, PhD, Instituto Politecnico Nacional; Silvia S. Pierangeli, PhD, University of Texas Medical Branch
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