New Concepts in the Autoimmune Pathogenesis of Interstitial Lung Diseases

Session Type: ACR Basic Science Symposia
Tuesday, November 8, 2011: 4:30 PM-6:00 PM
W183a (McCormick Place West)
Research  SessionSelect

Session Overview:
Interstitial lung disease develops as a sequelae of several autoimmune disorders, yet information regarding its immunopathogenesis, clinical progression, and effective treatment remains scarce. Recent developments in our scientific understanding of fibrogenesis, the biology of circulating fibrocytes, and potential biomarkers will be reviewed with the aim of catalyzing new avenues for investigation and approaches for treatment.

Upon completion of this session, participants should be able to:

  • identify current concepts of the immune pathogenesis of interstitial lung diseases
  • describe the role of fibrocytes in systemic fibroses and their biomarker potential
  • analyze the adaptive immune mechanisms that may govern fibrogenesis

Moderators: Richard J. Bucala, MD, PhD, Yale University School of Med and Carol A. Feghali-Bostwick, PhD, University of Pittsburgh
4:30 PM
Overview of Pathogenic Concepts in the Interstitial Lung Diseases
Carol A. Feghali-Bostwick, University of Pittsburgh, Pittsburgh, PA
4:55 PM
T-Cell Dependent Regulation of Fibrogenesis
Matthias Mack, University Hospital Regensburg, Regensburg, Germany
5:20 PM
Fibrocytes in Autoimmune Fibroses
Erica Herzog, Yale University School of Medicine, New Haven, CT
See more of: ACR Basic Science Symposia

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