Neutrophil Recruitment by Intravascular Danger Signals

Session Type: ACR State-of-the-Art Lectures
Tuesday, November 8, 2011: 9:00 AM-10:00 AM
W375a (McCormick Place West)
Research  SessionSelect

Session Overview:
Excessive neutrophil recruitment to sites of sterile inflammation can result in profound tissue destruction in autoimmune and inflammatory disorders. Improved understanding of the mechanisms by which neutrophils respond to sterile tissue injury is of critical importance in the search for agents that can shut down inflammation to prevent or minimize tissue damage.

Upon completion of this session, participants should be able to:

  • define the term damage associated molecular patterns and how these molecules participate in the inflammatory response
  • list the molecular signals that direct neutrophil migration
  • describe the multistep cascade that allows neutrophils to sense and home to sites of sterile inflammation

Moderator: Christopher T. Ritchlin, MD, MPH, University of Rochester Medical Center
9:00 AM
Paul Kubes, University of Calgary, Calgary, AB
See more of: ACR State-of-the-Art Lectures

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