The primary goal of this study group is to achieve a better standardization of Regulatory T cell (Treg) definition for analysis and functional assessment in human autoimmune disease research. Each year at the national ACR conference, multiple poster and oral presentations on Treg numbers and function are described with great variability in methods for determining identity and function of Tregs making it very difficult to draw meaningful conclusions between studies.
Upon completion of this session, participants should be able to:
- agree on a method to detect human resting and activated Tregs in various samples
- agree on a method to determine function of Tregs from various samples
- develop collaborations for studying Tregs that will lead to potential therapeutic interventions
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