The pathogenesis of primary osteoarthritis is still not well understood. Significant advances have been made in the role of alterations in chondrocyte behavior in the osteoarthritis disease process but this has not yet led to a functional pharmalogical therapy. However, since the chondrocyte is considered a major player in primary osteoarthritis, elucidation of the triggers that control chondrocyte behavior is of utmost importance to develop adequate osteoarthritis treatments.
Upon completion of this session, participants should be able to:
- discuss the role of the chondrocyte in the osteoarthritis disease process
- discuss the role of articular chondrocyte hypertrophy in osteoarthritis development and progression
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