Rheumatoid Arthritis - Animal Models

Session Type: ACR Abstract Submissions
Tuesday, November 8, 2011: 9:00 AM-6:00 PM
Hall F2 - Poster Hall (McCormick Place West)
Papers:
Importance of E3 Ubiquitin Ligase Synoviolin In Fibrogenesis
Naoko Yagishita1, Daisuke Hasegawa1, Satoko Aratani2, Yoshihisa Yamano1 and Toshihiro Nakajima2, 1St.Marianna University School of Medicine, Kawasaki, Kanagawa, Japan, 2Tokyo Medical University, Tokyo, Japan
Pemetrexed Ameliorates Experimental Arthritis in Rats
Metin Ozgen1, Suleyman Serdar Koca1, Ahmet Karatas1, Adile Ferda Dagli2, Fazilet Erman3, Nuran Sahin4, Kazim Sahin4 and Ahmet Isik1, 1Department of Rheumatology, Faculty of Medicine, Firat University, Elazig, Turkey, 2Department of Pathology, Faculty of Medicine, Firat University, Elazig, Turkey, 3School of Health Sciences, Firat University, Elazig, Turkey, 4Department of Animal Nutrition, Faculty of Veterinary Science, Firat University, Elazig, Turkey
Increased Density of Sympathetic Nerve Fibers in Metabolically Activated Fat Tissue Surrounding Human Synovium and Mouse Lymph Nodes in Arthritis
Christine Wolff1, Luise Rauch1, Torsten Lowin1, Susanne Klatt2 and Rainer H. Straub1, 1Laboratory of Exp. Rheumatology and Neuroendocrino-Immunology, Department of Internal Medicine I, University Hospital, Regensburg, Germany, 2Laboratory of Exp. Rheumatology and Neuroendocrino-Immunology, University Hospital, Regensburg, Germany
Gemcitabine Ameliorates Experimental Arthritis in Rats
Metin Ozgen1, Suleyman Serdar Koca1, Adile Ferda Dagli2, Ahmet Karatas1, Cemal Orhan3, Mehmet Tuzcu4, Nuran Sahin3, Kazim Sahin3 and Ahmet Isik1, 1Department of Rheumatology, Faculty of Medicine, Firat University, Elazig, Turkey, 2Department of Pathology, Faculty of Medicine, Firat University, Elazig, Turkey, 3Department of Animal Nutrition, Faculty of Veterinary Science, Elazig, Turkey, 4Department of Biology, Faculty of Science, Firat University, Elazig, Turkey
A Novel, Highly Selective Syk Kinase Inhibitor Significantly Ameliorates the Severity of Arthritis in Rodents
Zhong Cui Sun1, Yu Cai1, Yan Qiu1, Lei Fang1, Xiaoming Dai1, Zhipeng Wu1, Ping Ren1, Jianlin He1, Changwu Lu1, Yongjuan Yu1, Jian Wang1, Yang Sai1, James Yan1, Jia Li1, Wei Deng1, Weihan Zhang1, Jianguo Ji2, Weiguo Su1 and Haoran Zhao1, 1Hutchison Medipharma Limited, Shanghai, China, 2Abott, Shanghai, China
A Novel Role of h2-Calponin in the Development of Anti-GPI Serum-Induced Arthritis
M. Moazzem Hossain1, Qi Quan Huang2, Linda D. Hazlet3, Sharon A. McClellan3, Richard M. Pope2 and J.-P. Jin1, 1Departments of Physiology, Wayne State University School of Medicine, Detroit, MI, 2Division of Rheumatology, Northwestern University Feinberg School of Medicine, Chicago, IL, 3Anatomy and Cell Biology, Wayne State University School of Medicine, Detroit, MI
An Endogenous TLR2 Ligand Promotes Chronicity of Arthritis Which Is Modulated by Fas Signaling
Qi Quan Huang1, Alexander Misharin1, Robert Birtett1, Carla M. Cuda1, Christopher V. Nicchitta2, Harris R. Perlman1 and Richard M. Pope1, 1Northwestern University, Chicago, IL, 2Duke university Medical Center, Durham, NC
Suppression of Established Rat Collagen-Induced Arthritis and Inhibition of TNF-α with Small Molecule Aminopyridizines 
Soo I. Choi1, Lori D. Klaman2, Weiling Chen1 and Ernest Brahn1, 1UCLA School of Medicine, Los Angeles, CA, 2Transition Therapeutics, Toronto, ON
Treatments with Glycogen Synthase Kinase-3β Inhibitor Mitigate the Severity of Arthritis in Mice with Collagen-Induced Arthritis
Yong-Jin Kwon, Tae-Yeon Kim, Sang-Won Lee, Yong-Beom Park, Soo Kon Lee and Min-Chan Park, Yonse University College of Medicine, Seoul, South Korea
Pressure and Viscosity Measurements in Efferent Lymphatics to Better Understand the Mechanisms of Arthritic Flare and Response to Therapy
Echoe M. Bouta1, Ronald Wood1, Christopher T. Ritchlin2 and Edward M. Schwarz1, 1University of Rochester School of Medicine and Dentistry, Rochester, NY, 2University of Rochester Medical Center, Rochester, NY
IL-6 Blockade Augments the Therapeutic Effect of MTX in Mice with Glucose-6-Phosphate Isomerase-Induced Arthritis
Hiroto Yoshida1, Misato Hashizume1, Keisuke Tanaka1, Miho Suzuki1, Takayuki Sumida2, Isao Matsumoto2 and Masahiko Mihara1, 1Chugai Pharmaceutical Co., Ltd., Gotemba, Shizuoka, Japan, 2Division of Clinical Immunology, Doctoral Program in Clinical Sciences, Graduate School of Comprehensive Human Sciences, University of Tsukuba, Tsukuba, Ibaraki, Japan
Laquinimod Inhibits Disease Severity in Murine Collagen Induced Arthritis
Joel F. Kaye and Eran Blaugrund, Teva Pharmaceuticals Ltd, Netanya, Israel
Blocking the Granulocyte Macrophage Colony Stimulating Factor Receptor Alpha Chain Prevents Mechanical Hypersensitivity in a Mouse Model of Inflammatory Pain
John P. Hatcher, Justine Whitworth, Ian K. Anderson, Iain P. Chessell and Matthew A. Sleeman, MedImmune Ltd, Cambridge, United Kingdom
Prophylactic Injection of Non-Citrullinated Alpha-Enolase Has Immunomodulatory Effects in Collagen-Induced Arthritis Mice. 
Clément Guillou1, Gilles Avenel1, Céline Derambure1, Mathieu Verdet1, Martine Hiron1, Maude Maho1, Xavier Le Loët2, Sahil Adriouch1, Olivier Boyer1, Thierry Lequerré2 and Olivier Vittecoq2, 1Inserm 905 & Institute for Biomedical Research, University of Rouen, Rouen, France, 2Department of Rheumatology, Rouen University Hospital & Inserm 905, Institute for Biomedical Research, University of Rouen, Rouen, France
Preventive and Therapeutic Effects of Epigallocatechin-3-Gallate (EGCG) on Collagen-Induced Arthritis in Rats
Metin Ozgen1, Suleyman Serdar Koca1, Adile Ferda Dagli2, Ahmet Karatas1, Cemal Orhan3, Hasan Gencoglu4, Nurhan Sahin3, Kazim Sahin3 and Ahmet Isik1, 1Department of Rheumatology, Faculty of Medicine, Firat University, Elazig, Turkey, 2Department of Pathology, Faculty of Medicine, Firat University, Elazig, Turkey, 3Department of Animal Nutrition, Faculty of Veterinary Science, Elazig, Turkey, 4Department of Biology, Faculty of Science, Firat University, Elazig
Trichostatin A Induces CD8á Positive Tolerogenic Dendritic Cells, Regulatory T Cells in SKG Mice, and Ameliorates the Severe Arthritis
Kenta Misaki, Akio Morinobu, Jun Saegusa, Shimpei Kasagi, Masaaki Fujita, Yoshiaki Miyamoto, Fumichika Matsuki and Shunichi Kumagai, Kobe university graduate school of medicine, Kobe, Japan
Brucellosis-Induced Murine Arthritis and Spondylolisthesis
Elizabeth T. Lyons1, Diogo Magnani2, Toni S. Forde1, Gary Splitter2 and Vyacheslav A. Adarichev1, 1Albert Einstein College of Medicine, Bronx, NY, 2University of Wisconsin, Madison, WI
IL-23 Upregulates IRF5 and Polarizes Inflammatory M1 Macrophages to Promote Inflammation in a Mouse Model of Arthritis
Hao Li1, Hui-Chen Hsu1, Jun Li1, Qi Wu1, PingAr Yang1, Daniel Cua2 and John D. Mountz3, 1University of Alabama at Birmingham, Birmingham, AL, 2Merck Research Laboratory, Palo Alto, CA, 3University of Alabama at Birmingham and Birmingham VAMC, Birmingham, AL
Metformin Attenuated An Autoimmune Arthritis in Animal Models of Rheumatoid Arthritis Via AMP-Activated Protein Kinase Activation
Kwi Young Kang, Division of Rheumatology, Department of Internal Medicine, Chungbuk National University Hospital, Cheongju, South Korea, Inje Kim, Hallym University Kangdong Sacred Heart hospital, Seoul, South Korea and Ji Hyeon Ju, Division of Rheumatology, Department of Internal Medicine, School of Medicine, The Catholic University of Korea, Seoul, South Korea
SH3BP2 “Cherubism” Gain-of-Function Mutation Exacerbates Inflammation and Bone Erosion in Collagen Induced Arthritis
Tomoyuki Mukai1, Teruhito Yoshitaka1, Keiichiro Nishida2 and Yasuyoshi Ueki1, 1University of Missouri-Kansas City, Kansas City, MO, 2Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama city, Japan
Skin Fibroblasts Are Potent Suppressors of Inflammation in Experimental Arthritis
C. Bouffi1, C. Bony2, Christian Jorgensen3 and Daniele Noel1, 1UM1, Montpellier, France, 2INSERM U844, Montpellier, France, 3CHU Lapeyronie, Montpellier, France
Treatment of Collagen Induced Arthritis with Human Adipose-Derived, Bone Marrow-Derived and Cord Blood-Derived Mesenchymal Stem Cells
Kyu-Hyung Park, Ji-Hye Kim, Sang-Won Lee, Soo Kon Lee and Yong-Beom Park, Yonse University College of Medicine, Seoul, South Korea
A Novel Mouse Model of Atherosclerosis in Inflammatory Arthritis
Shawn M. Rose and Harris R. Perlman, Northwestern University, Chicago, IL
Arthritic ApoE-Deficient Mice Are Protected From the Development of Atherosclerosis
Shawn M. Rose and Harris R. Perlman, Northwestern University, Chicago, IL
See more of: ACR Abstract Submissions

To see other sessions for this day, use the date buttons to the left.