Affiliation Index: H

A B C D E F G H I J K L M N O P Q R S T U V W X Y Z
Haartman Institute
STAT3 Phosphorylation of Circulating Leukocytes Correlates with Disease Activity in Early Untreated Rheumatoid Arthritis
Krista Kuuliala1, Antti Kuuliala1, Saara Aittomäki1, Suvi Oksanen1, Sanna Siitonen2, Hannu Kautiainen3, Marjatta Leirisalo-Repo2 and Heikki Repo1, 1Haartman Institute, Helsinki, Finland, 2Helsinki University Central Hospital, Helsinki, Finland, 3Central Finland Central Hospital, Jyväskylä, Finland
Hacettepe University Faculty of Medicine
Patient-Perceived Impact of Psoriatic Arthritis Is Due to Pain and Fatigue, but Also to Psychological Aspects- the Psa Impact of Disease Study
Laure Gossec1, Maarten de Wit2, Andra Balanescu3, Peter V. Balint4, Gabor Békés4, Juergen Braun5, Juan D. Canete6, Laurence Carton7, Alina Dinte8, Kurt L. De Vlam9, Turid Heiberg10, Philip Helliwell11, Umut Kalyoncu12, Uta Kiltz13, Thomas Luger14, Mara Maccarone15, Ronan H. Mullan16, Dennis O'Sullivan16, Kati Otsa17, Andrew Parkinson18, Anselm Sanchez Lombarte6, Rossana Scrivo19, Josef Smolen20, Tanja A. Stamm21 and Tore K. Kvien22, 1Cochin Hospital, Paris, France, 2Dutch Arthritis Patient League, Amersfoort, Netherlands, 3University of Medicine and Pharmacy "Carol Davila", Bucharest, Romania, 4National Institute of Rheumatology and Physiotherapy, Budapest, Hungary, 5Ruhr-University Bochum, Herne, Germany, 6Hospital Clinic, Barcelona, Spain, 7Cochin Hospital and Association Française de Lutte Anti-Rhumatismale, Paris, France, 8“Sf. Maria” Hospital, Bucharest, Romania, 9University Hospital, Leuven, Belgium, 10Ullevaal Univ Hospital, Oslo, Norway, 11NIHR-Leeds Biomedical Research Unit and Leeds Institute of Molecular Medicine, University of Leeds, Leeds, United Kingdom, 12Hacettepe University Faculty of Medicine, Ankara, Turkey, 13Rheumazentrum Ruhrgebiet, Herne, Germany, 14University Hospital Münster, Münster, Germany, 15Associazione per la Difesa degli Psoriasici, Rome, Italy, 16St Vincent's University Hospital, Dublin, Ireland, 17Tallinn Central Hospital, Tallinn, Estonia, 18University of Leeds, Leeds, United Kingdom, 19Reumatologia - Sapienza Università di Roma, Rome, Italy, 20Medical University of Vienna and Hietzing Hospital, Vienna, Austria, 21Medical University of Vienna, Vienna, Austria, 22Diakonhjemmet Hospital, Oslo, Norway

Major Histocompatibility Complex Class II Gene Cluster Harbors Systemic Juvenile Idiopathic Arthritis Susceptibility Locus
Michael J. Ombrello1, Elaine Remmers1, Alexei A. Grom2, Wendy Thomson3, Alberto Martini4, Marco Gattorno5, Seza Ozen6, Ahmet Gul7, John F. Bohnsack8, Sampath Prahalad9, Andrew S. Zeft10, Elizabeth D. Mellins11, Colleen Satorius1, Jane L. Park11, Carl D. Langefeld12, Eleftheria Zeggini13, David N. Glass2, Susan D. Thompson2, Daniel L. Kastner1, Patricia Woo14 and International Childhood Arthritis Genetics Consortium15, 1National Human Genome Research Institute, National Institutes of Health, Bethesda, MD, 2Cincinnati Children's Hospital Medical Center, Cincinnati, OH, 3University of Manchester Medical School, Manchester, United Kingdom, 4IRCCS G Gaslini, Pediatria II, Reumatologia, Genova, Italy, 5Istituto di Ricovero e Cura a Carattere Scientifico G. Gaslini, Genova, Italy, 6Hacettepe University Faculty of Medicine, Ankara, Turkey, 7Istanbul University, Istanbul Faculty of Medicine, Istanbul, Turkey, 8University of Utah, Salt Lake City, UT, 9Emory Children's Center, Atlanta, GA, 10Cleveland Clinic, Cleveland, OH, 11Stanford University Medical Center, Stanford, CA, 12Wake Forest School of Medicine, Winston-Salem, NC, 13The Wellcome Trust Sanger Institute, Cambridge, United Kingdom, 14University College London Medical School, London, United Kingdom, 15Manchester, United Kingdom
Hackensack Univ Med Ctr
Description of the Localized Scleroderma Subgroup of the CARRAnet Registry
Eveline Y. Wu, Duke Univ Med Ctr, Durham, NC, Egla C. Rabinovich, Duke University Medical Center, Durham, NC, Kathryn S. Torok, Univ of Pittsburgh Med Ctr, Pittsburgh, PA, Suzanne C. Li, Hackensack Univ Med Ctr, Hackensack, NJ, Robert C. Fuhlbrigge, Childrens Hospital, Boston, MA and CARRANet Investigators, Stanford
Hackensack Univ Medical Ctr
Utilization of Biologic and Non-Biologic Disease Modifying Anti-Rheumatic Drugs in the Treatment of Juvenile Idiopathic Arthritis: A Cross-Sectional Analysis of the Childhood Arthritis and Rheumatology Research Alliance Registry
Timothy Beukelman, Univ of Alabama-Birmingham, Birmingham, AL, Sarah Ringold, Children's Hosp Regional Med, Seattle, WA, Trevor Davis, Floating Hospital for Children at Tufts Medical Center, Boston, MA, Esi M. Morgan DeWitt, Cincinnati Children's Hospital, Cincinnati, OH, Christina F. Pelajo, Tufts Medical Center, Boston, MA, Pamela Weiss, The Children's Hosp of Philade, Philadelphia, PA, Yukiko Kimura, Hackensack Univ Medical Ctr, Hackensack, NJ and for the CARRAnet investigators

Enthesitis Is a Significant Predictor of Decreased Quality of Life, Function, and Arthritis-Specific Pain Across Juvenile Idiopathic Arthritis (JIA) Categories: Preliminary Analyses From the CARRAnet Registry
Pamela Weiss, The Children's Hospital of Philadelphia, Philadelphia, PA, Timothy Beukelman, Univ of Alabama-Birmingham, Birmingham, AL, Laura E. Schanberg, Duke University Medical Center, Durham, NC, Yukiko Kimura, Hackensack Univ Medical Ctr, Hackensack, NJ, Robert A. Colbert, NIAMS NIH, Bethesda, MD and CARRANet Investigators, Stanford

Development of Consensus Treatment Plans for New-Onset Systemic Juvenile Idiopathic Arthritis
Esi Morgan DeWitt, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, Timothy Beukelman, Univ of Alabama-Birmingham, Birmingham, AL, Peter A. Nigrovic, Brigham and Women's Hospital, Boston, MA, Karen Onel, University of Chicago, Chicago, IL, Sampath Prahalad, Emory Children's Center, Atlanta, GA, Rayfel Schneider, Hospital for Sick Children, University of Toronto, Toronto, ON, Matthew Stoll, UT Southwestern Medical Center, Dallas, TX, Norman T. Ilowite, Children's Hospital Montefiore, Bronx, NY, Carol A. Wallace, Childrens Hosp & Regional Med, Seattle, WA and Yukiko Kimura, Hackensack Univ Medical Ctr, Hackensack, NJ

Trial of Early Aggressive Therapy in Polyarticular Juvenile Idiopathic Arthritis
Carol Wallace1, Edward H. Giannini2, Steven J. Spalding3, Philip Hashkes4, Kathleen M. O'Neil5, Andrew S. Zeft3, Ilona S. Szer6, Sarah Ringold7, Hermine Brunner8, Laura E. Schanberg9, Robert P. Sundel10, Diana Milojevic11, Marilynn G. Punaro12, Peter Chira13, Beth S. Gottlieb14, Gloria Higgins15, Norman T. Ilowite16, Yukiko Kimura17, Anne Johnson18, Stephanie Hamilton1, Bin Huang8 and Daniel J. Lovell8, 1Childrens Hosp & Regional Med, Seattle, WA, 2PRCSG-Cincinnati Children's Hospital Medical Center, Cincinnati, OH, 3Cleveland Clinic, Cleveland, OH, 4Shaare Zedek Medical Center, Tel Aviv, Israel, 5Okla Univ Health Science Ctr, Oklahoma City, OK, 6Rady Childrens Hosp San Diego, San Diego, CA, 7Children's Hosp Regional Med, Seattle, WA, 8Cincinnati Children's Hospital Medical Center, Cincinnati, OH, 9Duke University Medical Center, Durham, NC, 10Childrens Hosp Medical Center, Boston, MA, 11UCSF, San Francisco, CA, 12Texas Scottish Rite Hospital, Dallas, TX, 13Stanford University, Palo Alto, CA, 14Schneider Children's Hospital, New Hyde Park, NY, 15PRCSG, Columbus, OH, 16Children's Hospital Montefiore, Bronx, NY, 17Hackensack Univ Medical Ctr, Hackensack, NJ, 18Cincinnati Child Hosp Med Ctr, Cincinnati, OH

Measuring Quality of Care in Juvenile Idiopathic Arthritis: The Pediatric Rheumatology Care and Outcomes Improvement Network 
Esi Morgan DeWitt, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, Timothy Beukelman, Univ of Alabama-Birmingham, Birmingham, AL, Beth S. Gottlieb, Schneider Children's Hospital, New Hyde Park, NY, Nancy Griffin, Cincinnati Children's Hospital Medical Center, Cincinnati, Yukiko Kimura, Hackensack Univ Medical Ctr, Hackensack, NJ, Itara Barnes, American College of Rheumatology, Atlanta, GA and Murray H. Passo, MUSC, Charleston, SC
Hackensack University Medical Center
Development of a Clinical Disease Activity Measure for Juvenile Localized Scleroderma
Suzanne C. Li1, Kathryn S. Torok2, Elena Pope3, Katie G. Stewart4, Gloria C. Higgins5, Egla C. Rabinovich6, Kathleen M. O'Neil7, Ivan Foeldvari8, Kathleen A. Haines1, Heidi Jacobe9, Marilynn G. Punaro4, Ronald M. Laxer10, Themba Nyirenda1 and Knut M. Wittkowski11, 1Hackensack University Medical Center, Hackensack, NJ, 2Univ of Pittsburgh Med Ctr, Pittsburgh, PA, 3Hospital for Sick Children, Toronto, ON, 4Texas Scottish Rite Hospital, Dallas, TX, 5Nationwide Childrens Hosp, Columbus, OH, 6Duke University Medical Center, Durham, NC, 7Okla Univ Health Science Ctr, Oklahoma City, OK, 8Hamburger Zentrum Kinder-und Jugendrheumatologie, Hamburg, Germany, 9UT Southwestern Medical Center at Dallas, Dallas, TX, 10The Hospital for Sick Children, Toronto, ON, 11Rockefeller University, NY
Hadassah Hebrew University Medical Center
Determination of Pediatric Doses of Colchicine for Familial Mediterranean Fever on the Basis of Population Pharmacokinetics
Yackov Berkun1, Eldad Ben-Chetrit1, Suman Wason2, Robert Faulkner2 and Stephen Levenstein3, 1Hadassah Hebrew University Medical Center, Jerusalem, Israel, 2URL Pharma, Philadelphia, PA, 3GCP Clinical Studies Ltd., Rosh Ha’Ayin, Israel

Synovial Fluid Vγ9Vδ2 T Cells Activated by Synovial Fibroblasts  Induce Their Apoptosis
Anna Bendersky1, Victoria Marcu1, Yackov Berkun2, Itamar Goldstein1, Maya Gerstein1, Shay Padeh1 and Ilan Bank1, 1Sheba Medical Center, Ramat Gan, Israel, 2Hadassah Hebrew University Medical Center, Jerusalem, Israel
Hadassah University Hospital and the Hebrew University
Hadassah-Hebrew University Medical Center
A Humanized Monoclonal Antibody Against a Surface Ligand of Mononuclear Cells Suppress Autoimmune Inflammatory Diseases by Upregulation of IL-10 Secretion
Yaakov Naparstek, Rina Ulmansky, Galia Katzavian, Ronit Meyuhas, Alon Hershko, Eli Moallem, Shira Yair and Dorit Landstein, Hadassah-Hebrew University Medical Center, Jerusalem, Israel
Haematology
Thrombin Generation Indicates An Increased Risk for Thromboembolic Events in Lupus and Antiphospholipid Patients. A Prospective Cohort Study
Stephane Zuily, Vascular Medicine Unit, Vandoeuvre-Les-Nancy, France, Veronique Regnault, INSERM U961, Vandoeuvre, France, Francis Guillemin, Faculte de Medecin/BP 184, Vandoeuvre-les-Nancy, France, Pierre Kaminsky, Orphan disease Unit, Vandoeuvre, France, Thomas Lecompte, Haematology, Vandoeuvre and Denis Wahl, Nancy University Hospital and INSERM U961, Vandoeuvre-Les-Nancy, France
Haertelstrasse 16-18
Cytomegalovirus (CMV) and Rheumatoid Arthritis (RA) – a Critical Role of CMV Specific T Cells?
Kathrin Rothe1, Dagmar Quandt1, Matthias Pierer2, Anett Schulz1, Undine Meusch1, Manuela Rossol3, Roger Scholz2, Christoph G. Baerwald4 and Ulf Wagner4, 1University of Leipzig, Leipzig, Germany, 2Haertelstrasse 16-18, Leipzig, Germany, 3Translationszentrum für Regenerative Medizin (TRM), University of Leipzig, Leipzig, Germany, 4University Hospital, Leipzig, Germany
HAGA hospital
Rapid Radiological Progression in the First Year of RA Predicts Both Disability and Radiological Joint Damage Progression Over 8 Years of Targeted Treatment
M. van den Broek1, L. Dirven1, A.J. Dehpoor1, J.K. de Vries-Bouwstra1, Y.P. Goekoop-Ruiterman2, A.J. Peeters3, P.J.S.M. Kerstens4, Tom W.J. Huizinga1, W. F. Lems5 and C.F. Allaart1, 1Leiden University Medical Center, Leiden, Netherlands, 2HAGA hospital, The Hague, Netherlands, 3Reinier de Graaf Gasthuis, Delft, Netherlands, 4Jan van Breemen Research Institute | Reade, Amsterdam, Netherlands, 5VU University medical center, Amsterdam, Netherlands
Haga Hospital
Remission Induction Therapy with Methotrexate and Prednisone in Patients with Early Rheumatoid and Undifferentiated Arthritis
K.V.C. Wevers-de Boer1, L. Heimans1, K. Visser1, H.K. Ronday2, T.H.E. Molenaar3, P.E.H. Seys4, C. Bijkerk5, M.L. Westedt6, W. De Beus7, P.B. de Sonnaville8, T. Huizinga1 and C.F. Allaart1, 1Leiden University Medical Center, Leiden, Netherlands, 2Haga Hospital, The Hague, Netherlands, 3Groene Hart Hospital, Gouda, Netherlands, 4Franciscus Hospital, Roosendaal, Netherlands, 5Reinier de Graaf Gasthuis, Delft, Netherlands, 6Bronovo Hospital, The Hague, Netherlands, 7MCH, The Hague, Netherlands, 8Admiraal de Ruyter Hospital, Goes

Eight Year Results of Disease Activity Steered Treatment in a Large Recent Rheumatoid Arthritis Cohort: Clinical and Radiological Outcomes
Linda Dirven1, M. van den Broek1, N.B. Klarenbeek1, K.H. Han2, H.K Ronday3, P.J.S.M. Kerstens4, Tom W.J. Huizinga1, Willem F. Lems5 and C.F. Allaart1, 1Leiden University Medical Center, Leiden, Netherlands, 2Maasstad Hospital, Rotterdam, Netherlands, 3Haga Hospital, The Hague, Netherlands, 4Jan van Breemen Research Institute | Reade, Amsterdam, Netherlands, 5VU University medical center, Amsterdam, Netherlands

Optimism and Depressive Scores in Early Arthritis Patients Before and After Treatment with Methotrexate and a Tapered High Dose of Prednisone in the IMPROVED Study.
L. Heimans1, K.V.C. Wevers-de Boer1, K. Visser1, Tom W.J. Huizinga1, H.K Ronday2, M.L. Westedt3, T.H.E. Molenaar4, R.C. van der Mast1 and C.F. Allaart1, 1Leiden University Medical Center, Leiden, Netherlands, 2Haga Hospital, The Hague, Netherlands, 3Bronovo Hospital, The Hague, Netherlands, 4Groene Hart Hospital, Gouda, Netherlands
Hagaziekenhuis Juliana Children's Hospital
Etanercept in Juvenile Idiopathic Arthritis: Who Will Benefit? Results From the Dutch ABC Register
Marieke H. Otten1, Femke H.M. Prince1, Wineke Armbrust2, Rebecca Ten Cate3, Esther P.A.H. Hoppenreijs4, Marinka Twilt1, Yvonne Koopman-Keemink5, Simone L. Gorter6, Koert M. Dolman7, Joost F. Swart8, J. Merlijn Van den Berg9, Nico M. Wulffraat8, Marion A.J. Van Rossum10 and Lisette W.A. Van Suijlekom-Smit1, 1ErasmusMC Sophia Children's Hospital, Rotterdam, Netherlands, 2Beatrix Children's Hospital, University Medical Centre Groningen, Groningen, Netherlands, 3Leiden University Medical Centre, Leiden, Netherlands, 4St Maartenskliniek and Radboud University Nijmegen Medical Centre, Nijmegen, Netherlands, 5Hagaziekenhuis Juliana Children's Hospital, Den Haag, Netherlands, 6University Hospital Maastricht, Maastricht, Netherlands, 7St. Lucas Andreas Hospital and Reade Institute, Amsterdam, Netherlands, 8University Medical Center Utrecht, Utrecht, Netherlands, 9Emma Children's Hospital/ Academic Medical Centre and Reade Institute, Amsterdam, Netherlands, 10Emma Children's Hospital / Academic Medical Center (AMC), Amsterdam, Netherlands

Effectiveness and Safety of Switching Between Biologics in Juvenile Idiopathic Arthritis; Results From the Dutch ABC Register
Marieke H. Otten1, Femke H.M. Prince2, Janneke Anink1, Marion A. J. Van Rossum3, Esther P.A.H. Hoppenreijs4, Simone L. Gorter5, Wineke Armbrust6, Koert M. Dolman7, Yvonne Koopman-Keemink8, Joost F. Swart9, J. Merlijn Van den Berg10, Nico M. Wulffraat9, Rebecca Ten Cate11 and Lisette W.A. Van Suijlekom-Smit12, 1ErasmusMC Sophia Children's Hospital, Rotterdam, Netherlands, 2Brigham and Women's Hospital, Boston, MA, 3Emma Children's Hospital / Academic Medical Center (AMC), Amsterdam, Netherlands, 4St Maartenskliniek and Radboud University Nijmegen Medical Centre, Nijmegen, Netherlands, 5University Hospital Maastricht, Maastricht, Netherlands, 6Beatrix Children's Hospital, University Medical Centre Groningen, Groningen, Netherlands, 7St. Lucas Andreas Hospital and Reade Institute, Amsterdam, Netherlands, 8Hagaziekenhuis Juliana Children's Hospital, Den Haag, Netherlands, 9University Medical Center Utrecht, Utrecht, Netherlands, 10Emma Children's Hospital/ Academic Medical Centre and Reade Institute, Amsterdam, Netherlands, 11Leiden University Medical Center, Leiden, Netherlands, 12ErasmusMC Sophia Childrens Hospital, Rotterdam, Netherlands
Hallym University Kangdong Sacred Heart hospital
the Clinical Characteristics of Rheumatoid Arthritis Patients in Clinical Remission: Many Faces of DAS-28 Remission
Kyeong Min Son1, Inje Kim2 and Hyun Ah Kim1, 1Hallym university sacred heart hospital, Kyunggi, South Korea, 2Hallym University Kangdong Sacred Heart hospital, Seoul, South Korea

The Association Between Bone Marrow Lesion Detected by Magnetic Resonance Imaging and Knee Pain in the Community Residents in Korea
Inje Kim, Hallym University Kangdong Sacred Heart hospital, Seoul, South Korea, Yeong Wook Song, Seoul National University College of Medicine, Seoul, South Korea, Hyun Ah Kim, Hallym University Sacred Heart Hospital, Kyunggi, South Korea and Ali Guermazi, Boston Medical Center, Boston, MA

Metformin Attenuated An Autoimmune Arthritis in Animal Models of Rheumatoid Arthritis Via AMP-Activated Protein Kinase Activation
Kwi Young Kang, Division of Rheumatology, Department of Internal Medicine, Chungbuk National University Hospital, Cheongju, South Korea, Inje Kim, Hallym University Kangdong Sacred Heart hospital, Seoul, South Korea and Ji Hyeon Ju, Division of Rheumatology, Department of Internal Medicine, School of Medicine, The Catholic University of Korea, Seoul, South Korea
Hallym university sacred heart hospital
the Clinical Characteristics of Rheumatoid Arthritis Patients in Clinical Remission: Many Faces of DAS-28 Remission
Kyeong Min Son1, Inje Kim2 and Hyun Ah Kim1, 1Hallym university sacred heart hospital, Kyunggi, South Korea, 2Hallym University Kangdong Sacred Heart hospital, Seoul, South Korea
Hallym University Sacred Heart Hospital
The Association Between Bone Marrow Lesion Detected by Magnetic Resonance Imaging and Knee Pain in the Community Residents in Korea
Inje Kim, Hallym University Kangdong Sacred Heart hospital, Seoul, South Korea, Yeong Wook Song, Seoul National University College of Medicine, Seoul, South Korea, Hyun Ah Kim, Hallym University Sacred Heart Hospital, Kyunggi, South Korea and Ali Guermazi, Boston Medical Center, Boston, MA
Hamburger Zentrum Kinder-und Jugendrheumatologie
Effects of Switching From Etanercept to Adalimumab in Juvenile Idiopathic Arthritis
Gerd Horneff, Asklepios Clinic Sankt Augustin, Sankt Augustin, Germany, Ivan Foeldvari, Hamburger Zentrum Kinder-und Jugendrheumatologie, Hamburg, Germany, Gerd Ganser, Sankt Josef Stift, Sendenhorst, Germany, Johannes Peter Haas, Childrens Hospital, Erlangen, Germany, Kirsten Minden, Charite, Berlin, Germany and Hans-Iko Huppertz, Krinikum Bremen-Mitte, Bremen, Germany

Development of a Clinical Disease Activity Measure for Juvenile Localized Scleroderma
Suzanne C. Li1, Kathryn S. Torok2, Elena Pope3, Katie G. Stewart4, Gloria C. Higgins5, Egla C. Rabinovich6, Kathleen M. O'Neil7, Ivan Foeldvari8, Kathleen A. Haines1, Heidi Jacobe9, Marilynn G. Punaro4, Ronald M. Laxer10, Themba Nyirenda1 and Knut M. Wittkowski11, 1Hackensack University Medical Center, Hackensack, NJ, 2Univ of Pittsburgh Med Ctr, Pittsburgh, PA, 3Hospital for Sick Children, Toronto, ON, 4Texas Scottish Rite Hospital, Dallas, TX, 5Nationwide Childrens Hosp, Columbus, OH, 6Duke University Medical Center, Durham, NC, 7Okla Univ Health Science Ctr, Oklahoma City, OK, 8Hamburger Zentrum Kinder-und Jugendrheumatologie, Hamburg, Germany, 9UT Southwestern Medical Center at Dallas, Dallas, TX, 10The Hospital for Sick Children, Toronto, ON, 11Rockefeller University, NY

Double Blind, Placebo-Controlled Trial with Adalimumab for Treatment of Juvenile Ankylosing Spondylitis (jAS)
Gerd Horneff1, Sigrid Fitter1, Hans-Iko Huppertz2, Ivan Foeldvari3, Jasmin B. Kuemmerle-Deschner4, Rolf M. Kuester5, Nikolay Tzaribachev6, Angelika Thon7, Michael Borte8, Gerd Ganser9, Ralf Trauzeddel10 and Kirsten Minden11, 1Asklepios Clinic Sankt Augustin, Sankt Augustin, Germany, 2Krinikum Bremen-Mitte, Bremen, Germany, 3Hamburger Zentrum Kinder-und Jugendrheumatologie, Hamburg, Germany, 4University Hospital Tuebingen, Tuebingen, Germany, 5Rheumaklinik Bad Bramstedt, Bad Bramstedt, Germany, 6Center for Rheumatic Diseases, Bad Bramstedt, Germany, 7Kinderklinik der Medizinischen Hochschule Hannover, Hannover, Germany, 8Sankt Georg Clinics, Leeipzig, Germany, 9Sankt Josef Stift, Sendenhorst, Germany, 10Helios Clinics, Berlin, Germany, 11Charite, Berlin, Germany

Approaches and Timing of TMJ Arthritis Screening by Pediatric Rheumatologists
Ivan Foeldvari, Hamburger Zentrum Kinder-und Jugendrheumatologie, Hamburg, Germany

Adaptation and Validation of Outcome Measures for Pediatric Uveitis
Ivan Foeldvari, Hamburger Zentrum Kinder-und Jugendrheumatologie, Hamburg, Germany
Hand Surgery, Salford Royal NHS Foundation Trust
Digital Ulcers in Patients with Systemic Sclerosis: Prevalence, Location, Nailfold Capillaroscopy and Functional Impact
Holly Ennis1, A. Vail2, Elizabeth Wragg3, Adrienne Taylor3, Tonia Moore1, Andrea Murray1, Lindsay Muir4, Christopher E.M Griffiths5 and Ariane L. Herrick1, 1School of Translational Medicine, University of Manchester, Manchester Academic Health Science Centre, Manchester, United Kingdom, 2School of Community Based Medicine, University of Manchester, Manchester Academic Health Science Centre, Manchester, United Kingdom, 3Rheumatology Directorate, Salford Royal NHS Foundation Trust, Salford, United Kingdom, 4Hand Surgery, Salford Royal NHS Foundation Trust, Salford, United Kingdom, 5Dermatology Centre, University of Manchester, Manchester Academic Health Science Centre, Manchester, United Kingdom

Systemic Sclerosis-Related Digital Ulcers: Influence of Location, Calcinosis and Perfusion on Time to Healing
Andrea Murray1, Tonia Moore1, Elizabeth Wragg2, Holly Ennis1, Andy Vail3, Adrienne Taylor2, Graham Dinsdale1, Lindsay Muir4, Charles Hutchinson1, Christopher E.M Griffiths5 and Ariane Herrick1, 1School of Translational Medicine, University of Manchester, Manchester Academic Health Science Centre, Manchester, United Kingdom, 2Rheumatology Directorate, Salford Royal NHS Foundation Trust, Salford, United Kingdom, 3School of Community Based Medicine, University of Manchester, Manchester Academic Health Science Centre, Salford, United Kingdom, 4Hand Surgery, Salford Royal NHS Foundation Trust, Salford, United Kingdom, 5University of Manchester, Manchester Academic Health Science Centre, Manchester, United Kingdom
Hannover Medical School
A High-Density Genome-Wide Association Study by the Sjögren’s Genetics Network Identifies Five Novel Susceptibility Loci for Primary Sjögren’s Syndrome and Confirms Association with MHC, IRF5, and BLK
Christopher J. Lessard1, John A. Ice1, Indra Adrianto1, Jennifer A. Kelly1, Roland Jonsson2, Gabor G. Illei3, Maureen Rischmueller4, Gunnel Nordmark5, Xavier Mariette6, Corinne Miceli-Richard6, Marie Wahren Herlenius7, Torsten Witte8, Michael T. Brennan9, Roald Omdal10, Timothy J. Vyse11, James A. Lessard12, Wan-Fai Ng13, Nelson L. Rhodus14, Barbara M. Segal15, R. Hal Scofield1, Benjamin A. Rybicki for ACCESS16, Juan-Manuel Anaya17, John B. Harley18, Courtney G. Montgomery1 and Kathy L. Moser19, 1Oklahoma Medical Research Foundation, Oklahoma City, OK, 2University of Bergen, Bergen, Norway, 3NIDCR/ NIH #10 1N110, Bethesda, MD, 4Queen Elizabeth Hospital, Adelaide, Australia, 5Department of Medical Sciences, Section of Rheumatology, Uppsala University, Uppsala, Sweden, 6Bicêtre University Hospital, Le Kremlin Bicêtre, France, 7Karolinska Institute, Stockholm, Sweden, 8Hannover Medical School, Hanover, Germany, 9Carolinas Medical Center, Charlotte, NC, 10Clinical Immunology Unit, Department of Internal Medicine, Stavanger University Hospital, Stavanger, Norway, 11Divisions of Genetics and Molecular Medicine and Immunology, King's College London, London, United Kingdom, 12Valley Bone & Joint Clinic, Grand Forks, ND, 13Musculoskeletal Research Group Institute of Cellular Medicine, Newcastle University, Newcastle, England, 14University of Minnesota, Minneapolis, MN, 15Hennepin County Medical Center, Minneapolis, MN, 16Henry Ford Hospital, Detroit, MI, 17Universidad del Rosario-Corporacion para Investigaciones Biologicas, Bogota, Colombia, 18Cincinnati Children's Hospital Medical Center and the US Department of Veterans Affairs Medical Center, Cincinnati, OH, 19Arthritis and Clinical Immunology Research Program, Oklahoma Medical Research Foundation, Oklahoma City, OK

Triple X Syndrome (47,XXX) Increases the Risk and Accelerates the Onset of Systemic Lupus Erythematosus and Sjögren's Syndrome: Support for a Gene-Dose Effect From the X Chromosome
Skyler P. Dillon1, Lydia Kao1, Kenneth M. Kaufman2, John A. Ice2, Roald Omdal3, Xavier Mariette4, Torsten Witte5, Gabor G. Illei6, Maureen Rischmueller7, Gunnel Nordmark8, Roland Jonsson9, Marie Wahren Herlenius10, Timothy J. Vyse11, Michael T. Brennan12, Benjamin A. Rybicki13, Wan-Fai Ng14, Barbara M. Segal15, Nelson L. Rhodus16, Joan T. Merrill2, Courtney G. Montgomery2, Christopher J. Lessard2, John B. Harley17, Kathy L. Moser18, Patrick M. Gaffney18 and R. Hal Scofield2, 1University of Oklahoma Health Sciences Center, Oklahoma City, OK, 2Oklahoma Medical Research Foundation, Oklahoma City, OK, 3Clinical Immunology Unit, Department of Internal Medicine, Stavanger University Hospital, Stavanger, Norway, 4Université Paris-Sud, Le Kremlin Bicetre, France, 5Hannover Medical School, Hanover, Germany, 6NIDCR/ NIH #10 1N110, Bethesda, MD, 7Queen Elizabeth Hospital, Adelaide, Australia, 8Department of Medical Sciences, Section of Rheumatology, Uppsala University, Uppsala, Sweden, 9University of Bergen, Bergen, Norway, 10CMM L8204 Karolinska Hosp, Stockholm, Sweden, 11Divisions of Genetics and Molecular Medicine and Immunology, King's College London, London, United Kingdom, 12Carolinas Medical Center, Charlotte, NC, 13Henry Ford Health System, Detroit, MI, 14Newcastle University, Newcastle upon Tyne, United Kingdom, 15Hennepin County Medical Center, Minneapolis, MN, 16University of Minnesota, Minneapolis, MN, 17Cincinnati Children's Hospital Medical Center and the US Department of Veterans Affairs Medical Center, Cincinnati, OH, 18Arthritis and Clinical Immunology Research Program, Oklahoma Medical Research Foundation, Oklahoma City, OK

Large-Scale, High-Density Genotyping Performed by the Sjögren’s Genetics Network Using the ImmunoChip Identifies PRKRA as a Novel Sjögren's Syndrome Susceptibility Locus and Confirms Associations with IRF5, BLK and MHC
Christopher J. Lessard1, Indra Adrianto1, John A. Ice1, Jennifer A. Kelly1, Roland Jonsson2, Gabor G. Illei3, Maureen Rischmueller4, Gunnel Nordmark5, Xavier Mariette6, Corinne Miceli-Richard6, Marie Wahren Herlenius7, Torsten Witte8, Michael T. Brennan9, Roald Omdal10, Patrick M. Gaffney11, James A. Lessard12, Wan-Fai Ng13, Nelson L. Rhodus14, Barbara M. Segal15, R. Hal Scofield1, Judith A. James16, Juan-Manuel Anaya17, John B. Harley18, Courtney Montgomery1 and Kathy L. Moser11, 1Oklahoma Medical Research Foundation, Oklahoma City, OK, 2University of Bergen, Bergen, Norway, 3NIDCR/ NIH #10 1N110, Bethesda, MD, 4Queen Elizabeth Hospital, Adelaide, Australia, 5Department of Medical Sciences, Section of Rheumatology, Uppsala University, Uppsala, Sweden, 6Bicêtre University Hospital, Le Kremlin Bicêtre, France, 7Karolinska Institute, Stockholm, Sweden, 8Hannover Medical School, Hanover, Germany, 9Carolinas Medical Center, Charlotte, NC, 10Clinical Immunology Unit, Department of Internal Medicine, Stavanger University Hospital, Stavanger, Norway, 11Arthritis and Clinical Immunology Research Program, Oklahoma Medical Research Foundation, Oklahoma City, OK, 12Valley Bone & Joint Clinic, Grand Forks, ND, 13Musculoskeletal Research Group Institute of Cellular Medicine, Newcastle University, Newcastle, England, 14University of Minnesota, Minneapolis, MN, 15Hennepin County Medical Center, Minneapolis, MN, 16Oklahoma Medical Research Foundation and Oklahoma University Health Sciences Center, Oklahoma City, OK, 17Universidad del Rosario-Corporacion para Investigaciones Biologicas, Bogota, Colombia, 18Cincinnati Children's Hospital Medical Center and the US Department of Veterans Affairs Medical Center, Cincinnati, OH

Association of Ferritin Antibodies with GCA/PMR: New Biomarker for Diagnosis
Niklas T. Baerlecken, MD, Hannover, Germany, Anna Linnemann, Student, Hannover, Germany, Wolfgang L. Gross, Medical University at Lubeck, Lubeck, Germany, Frank Moosig, Stormarnzing 156, Bad Bramstedt, Germany, T.R. Vazquez-Rodriguez, MD, Spain, Miguel Gonzalez-Gay, Hospital Marques De Valdecilla, Santander, Spain, Javier Martin, Instituto de Parasitologia y Biomedicina Lopez-Neyra (CSIC), Granada, Spain, Ina Kötter, MD, Tübingen, Germany, Joerg C. Henes, University Hospital Tuebingen, Tuebingen, Germany, Inga Melchers, PhD, Freiburg, Germany, Peter Vaith, Medizinische Uni Klinik, Freiburg, Germany, Reinhold E. Schmidt, Hannover Medical School, Hannover, Germany and Torsten Witte, MD, Hanover, Germany

Autoantibodies Against CD74 and Class II-Associated Invariant Chain Peptide (CLIP) in Spondyloarthritis
Niklas T. Baerlecken, MD, Hannover, Germany, Georg H. Stummvoll, Medical University of Vienna, Vienna, Austria, Reinhold E. Schmidt, Hannover Medical School, Hannover, Germany and Torsten Witte, Hannover Medical School, Hanover, Germany
Hanusch Hospital
MAPK-Activated Protein Kinase-2 (MK2) Regulates Bone Homeostasis
Tobias Braun1, Johannes Lepper1, Gisela Ruiz Heiland1, Georg Schett1 and Jochen Zwerina2, 1University of Erlangen-Nuremberg, Erlangen, Germany, 2Hanusch Hospital, Vienna, Austria
Hanyang University Hospital
Tofacitinib (CP-690,550), An Oral Janus Kinase Inhibitor, in the Treatment of Rheumatoid Arthritis: Open-Label, Long-Term Extension Studies up to 36 Months
J. Wollenhaupt1, J. C Silverfield2, E. B. Lee3, S. Wood4, K. Soma5, L. Wang5, H. Nakamura6, Y. Komuro6, C. I. Nduaka5, D. Gruben5, S. H. Zwillich5 and J. D. Bradley5, 1Teaching Hospital of the University of Hamburg, Hamburg, Germany, 2Tampa Medical Group, P.A., Tampa, FL, 3Hanyang University Hospital, Seoul, 4Pfizer Inc., Groton, NJ, 5Pfizer Inc., Groton, CT, 6Pfizer Inc., Tokyo, Japan
Hanyang University Hospital for Rheumatic Disease
Do Patients with Elderly-Onset Rheumatoid Arthritis Have Severe Functional Disability?
Soo-Kyung Cho1, Yoon-Kyoung Sung1, So-Yeon Park1, Jeeseon Shim2, Chan-Bum Choi3, Hoon-Suk Cha4, Jung-Yoon Choe5, Won-Tae Chung6, Seung-Jae Hong7, Jae Bum Jun8, Tae-Hwan Kim9, Tae-Jong Kim10, Eun-Mi Koh4, Jisoo Lee11, Shin-Seok Lee10, Sung Won Lee6, Wan-sik Uhm8, Dae-Hyun Yoo9, Bo Young Yoon12, Sang-Cheol Bae1 and KORONA investigators13, 1Hanyang University Hospital for Rheumatic Diseases, Clinical Research Center for Rheumatoid Arthritis (CRCRA), Seoul, South Korea, 2Clinical Research Center for Rheumatoid Arthritis (CRCRA), Seoul, South Korea, 3Hanyang University Hospital for Rheumatic Disease, Clinical Research Center for Rheumatoid Arthritis (CRCRA), Seoul, South Korea, 4Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, South Korea, 5Catholic university of Daegu, School of mediine, Daegu, South Korea, 6Dong-A University Hospital, Busan, South Korea, 7Kyung Hee University Hospital, Seoul, South Korea, 8Hanyang University Hospital for Rheumatic Disease, Seoul, South Korea, 9Hanyang University Hospital for Rheumatic Diseases, Seoul, South Korea, 10Chonnam National University Medical School and Hospital, Gwangju, South Korea, 11Ewha Womans University Mokdong Hospital, Seoul, South Korea, 12Inje University Ilsan Paik Hospital, Goyang, South Korea, 13Seoul

What Factors Affect Discordance Between Physicians and Patients in Assessments of Global Health in Rheumatoid Arthritis?
Soo-Kyung Cho1, Yoon-Kyoung Sung1, So-Yeon Park1, Jeeseon Shim2, Chan-Bum Choi3, Hoon-Suk Cha4, Jung-Yoon Choe5, Won-Tae Chung6, Jae Bum Jun7, Tae-Hwan Kim8, Tae-Jong Kim9, Eun-Mi Koh4, Jisoo Lee10, Shin-Seok Lee9, Sung Hoon Park5, Wan-sik Uhm7, Dae-Hyun Yoo8, Bo Young Yoon11, Sang-Cheol Bae1 and KORONA investigators12, 1Hanyang University Hospital for Rheumatic Diseases, Clinical Research Center for Rheumatoid Arthritis (CRCRA), Seoul, South Korea, 2Clinical Research Center for Rheumatoid Arthritis (CRCRA), Seoul, South Korea, 3Hanyang University Hospital for Rheumatic Disease, Clinical Research Center for Rheumatoid Arthritis (CRCRA), Seoul, South Korea, 4Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, South Korea, 5Catholic University of Daegu School of Medicine, Daegu, South Korea, 6Dong-A University, Busan, South Korea, 7Hanyang University Hospital for Rheumatic Disease, Seoul, South Korea, 8Hanyang University Hospital for Rheumatic Diseases, Seoul, South Korea, 9Chonnam National University Medical School and Hospital, Gwangju, South Korea, 10Ewha Womans University Mokdong Hospital, Seoul, South Korea, 11Inje University Ilsan Paik Hospital, Goyang, South Korea, 12Seoul, South Korea

Impact of Comorbidities on TNF Inhibitor Persistence in Rheumatoid Arthritis Patients : An Analysis of Korean National Health Insurance Claims Data
Soo-Kyung Cho1, Yoon-Kyoung Sung1, Chan-Bum Choi2, Jae Hoon Kim3, Jin Ju Kim4, Joo-Hyun Lee4, Young Bin Joo4 and Sang-Cheol Bae1, 1Hanyang University Hospital for Rheumatic Diseases, Clinical Research Center for Rheumatoid Arthritis (CRCRA), Seoul, South Korea, 2Hanyang University Hospital for Rheumatic Disease, Clinical Research Center for Rheumatoid Arthritis (CRCRA), Seoul, South Korea, 3Hanyang University Hospital for Rheumatic Disease, Seoul, South Korea, 4Hanyang University Hospital for Rheumatic Diseases, Seoul, South Korea
Hanyang University Hospital for Rheumatic Disease, Clinical Research Center for Rheumatoid Arthritis (CRCRA)
Do Patients with Elderly-Onset Rheumatoid Arthritis Have Severe Functional Disability?
Soo-Kyung Cho1, Yoon-Kyoung Sung1, So-Yeon Park1, Jeeseon Shim2, Chan-Bum Choi3, Hoon-Suk Cha4, Jung-Yoon Choe5, Won-Tae Chung6, Seung-Jae Hong7, Jae Bum Jun8, Tae-Hwan Kim9, Tae-Jong Kim10, Eun-Mi Koh4, Jisoo Lee11, Shin-Seok Lee10, Sung Won Lee6, Wan-sik Uhm8, Dae-Hyun Yoo9, Bo Young Yoon12, Sang-Cheol Bae1 and KORONA investigators13, 1Hanyang University Hospital for Rheumatic Diseases, Clinical Research Center for Rheumatoid Arthritis (CRCRA), Seoul, South Korea, 2Clinical Research Center for Rheumatoid Arthritis (CRCRA), Seoul, South Korea, 3Hanyang University Hospital for Rheumatic Disease, Clinical Research Center for Rheumatoid Arthritis (CRCRA), Seoul, South Korea, 4Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, South Korea, 5Catholic university of Daegu, School of mediine, Daegu, South Korea, 6Dong-A University Hospital, Busan, South Korea, 7Kyung Hee University Hospital, Seoul, South Korea, 8Hanyang University Hospital for Rheumatic Disease, Seoul, South Korea, 9Hanyang University Hospital for Rheumatic Diseases, Seoul, South Korea, 10Chonnam National University Medical School and Hospital, Gwangju, South Korea, 11Ewha Womans University Mokdong Hospital, Seoul, South Korea, 12Inje University Ilsan Paik Hospital, Goyang, South Korea, 13Seoul

What Factors Affect Discordance Between Physicians and Patients in Assessments of Global Health in Rheumatoid Arthritis?
Soo-Kyung Cho1, Yoon-Kyoung Sung1, So-Yeon Park1, Jeeseon Shim2, Chan-Bum Choi3, Hoon-Suk Cha4, Jung-Yoon Choe5, Won-Tae Chung6, Jae Bum Jun7, Tae-Hwan Kim8, Tae-Jong Kim9, Eun-Mi Koh4, Jisoo Lee10, Shin-Seok Lee9, Sung Hoon Park5, Wan-sik Uhm7, Dae-Hyun Yoo8, Bo Young Yoon11, Sang-Cheol Bae1 and KORONA investigators12, 1Hanyang University Hospital for Rheumatic Diseases, Clinical Research Center for Rheumatoid Arthritis (CRCRA), Seoul, South Korea, 2Clinical Research Center for Rheumatoid Arthritis (CRCRA), Seoul, South Korea, 3Hanyang University Hospital for Rheumatic Disease, Clinical Research Center for Rheumatoid Arthritis (CRCRA), Seoul, South Korea, 4Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, South Korea, 5Catholic University of Daegu School of Medicine, Daegu, South Korea, 6Dong-A University, Busan, South Korea, 7Hanyang University Hospital for Rheumatic Disease, Seoul, South Korea, 8Hanyang University Hospital for Rheumatic Diseases, Seoul, South Korea, 9Chonnam National University Medical School and Hospital, Gwangju, South Korea, 10Ewha Womans University Mokdong Hospital, Seoul, South Korea, 11Inje University Ilsan Paik Hospital, Goyang, South Korea, 12Seoul, South Korea

Impact of Comorbidities on TNF Inhibitor Persistence in Rheumatoid Arthritis Patients : An Analysis of Korean National Health Insurance Claims Data
Soo-Kyung Cho1, Yoon-Kyoung Sung1, Chan-Bum Choi2, Jae Hoon Kim3, Jin Ju Kim4, Joo-Hyun Lee4, Young Bin Joo4 and Sang-Cheol Bae1, 1Hanyang University Hospital for Rheumatic Diseases, Clinical Research Center for Rheumatoid Arthritis (CRCRA), Seoul, South Korea, 2Hanyang University Hospital for Rheumatic Disease, Clinical Research Center for Rheumatoid Arthritis (CRCRA), Seoul, South Korea, 3Hanyang University Hospital for Rheumatic Disease, Seoul, South Korea, 4Hanyang University Hospital for Rheumatic Diseases, Seoul, South Korea
Hanyang University Hospital for Rheumatic Diseases
Prevalence and Incidence of Rheumatoid Arthritis in South Korea
Yoon-Kyoung Sung1, Soo-Kyung Cho1, Chan-Bum Choi1, Jae Hoon Kim2, Jin Ju Kim2, Joo-Hyun Lee2, Young Bin Joo2 and Sang-Cheol Bae1, 1Hanyang University Hospital for Rheumatic Diseases, Clinical Research Center for Rheumatoid Arthritis (CRCRA), Seoul, South Korea, 2Hanyang University Hospital for Rheumatic Diseases, Seoul, South Korea

Do Patients with Elderly-Onset Rheumatoid Arthritis Have Severe Functional Disability?
Soo-Kyung Cho1, Yoon-Kyoung Sung1, So-Yeon Park1, Jeeseon Shim2, Chan-Bum Choi3, Hoon-Suk Cha4, Jung-Yoon Choe5, Won-Tae Chung6, Seung-Jae Hong7, Jae Bum Jun8, Tae-Hwan Kim9, Tae-Jong Kim10, Eun-Mi Koh4, Jisoo Lee11, Shin-Seok Lee10, Sung Won Lee6, Wan-sik Uhm8, Dae-Hyun Yoo9, Bo Young Yoon12, Sang-Cheol Bae1 and KORONA investigators13, 1Hanyang University Hospital for Rheumatic Diseases, Clinical Research Center for Rheumatoid Arthritis (CRCRA), Seoul, South Korea, 2Clinical Research Center for Rheumatoid Arthritis (CRCRA), Seoul, South Korea, 3Hanyang University Hospital for Rheumatic Disease, Clinical Research Center for Rheumatoid Arthritis (CRCRA), Seoul, South Korea, 4Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, South Korea, 5Catholic university of Daegu, School of mediine, Daegu, South Korea, 6Dong-A University Hospital, Busan, South Korea, 7Kyung Hee University Hospital, Seoul, South Korea, 8Hanyang University Hospital for Rheumatic Disease, Seoul, South Korea, 9Hanyang University Hospital for Rheumatic Diseases, Seoul, South Korea, 10Chonnam National University Medical School and Hospital, Gwangju, South Korea, 11Ewha Womans University Mokdong Hospital, Seoul, South Korea, 12Inje University Ilsan Paik Hospital, Goyang, South Korea, 13Seoul

What Factors Affect Discordance Between Physicians and Patients in Assessments of Global Health in Rheumatoid Arthritis?
Soo-Kyung Cho1, Yoon-Kyoung Sung1, So-Yeon Park1, Jeeseon Shim2, Chan-Bum Choi3, Hoon-Suk Cha4, Jung-Yoon Choe5, Won-Tae Chung6, Jae Bum Jun7, Tae-Hwan Kim8, Tae-Jong Kim9, Eun-Mi Koh4, Jisoo Lee10, Shin-Seok Lee9, Sung Hoon Park5, Wan-sik Uhm7, Dae-Hyun Yoo8, Bo Young Yoon11, Sang-Cheol Bae1 and KORONA investigators12, 1Hanyang University Hospital for Rheumatic Diseases, Clinical Research Center for Rheumatoid Arthritis (CRCRA), Seoul, South Korea, 2Clinical Research Center for Rheumatoid Arthritis (CRCRA), Seoul, South Korea, 3Hanyang University Hospital for Rheumatic Disease, Clinical Research Center for Rheumatoid Arthritis (CRCRA), Seoul, South Korea, 4Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, South Korea, 5Catholic University of Daegu School of Medicine, Daegu, South Korea, 6Dong-A University, Busan, South Korea, 7Hanyang University Hospital for Rheumatic Disease, Seoul, South Korea, 8Hanyang University Hospital for Rheumatic Diseases, Seoul, South Korea, 9Chonnam National University Medical School and Hospital, Gwangju, South Korea, 10Ewha Womans University Mokdong Hospital, Seoul, South Korea, 11Inje University Ilsan Paik Hospital, Goyang, South Korea, 12Seoul, South Korea

Association Between Clinical Factors and Radiographic Severity in Ankylosing Spondylitis
Tae-Jong Kim, Chonnam National University Medical School and Hospital, Gwangju, South Korea, Seung-Hun Lee, South Korea, Kyung-Bin Joo, Hanynag University, Seoul, South Korea and Tae-Hwan Kim, Hanyang University Hospital for Rheumatic Diseases, Seoul, South Korea

Biologics use in SLE in 23 Centers - Data from the International Registry for Biologics In SLE (IRBIS)
R.F. van Vollenhoven1, Søren Jacobsen2, Daniel Wallace3, John G. Hanly4, Michelle Petri5, David A. Isenberg6, Sasha Bernatsky7, Sang-Cheol Bae8, Manuel Ramos-Casals9, Guillermo Ruiz-Irastorza10, Francisco J. García-Hernández11, Luis Saez12, José Luis Callejas13, Javier Rascón14, Enrique de Ramón15, Mª Mar Ayala-Gutiérrez15, Maite Camps15, Melinda Mild16, Murat Inanç17, Bahar Artim-Esen17, Rosalind Ramsey-Goldman18, Christine A. Peschken19, Danilo Squatrito20, László Kovács21, Andrea Doria22, Zoltan Szekanecz23, Elisa Gremese24 and Emilia I. Sato25, 1Karolinska University Hospital, Stockholm, Sweden, 2Copenhagen University Hospital, Copenhagen, Denmark, 3Cedars-Sinai/UCLA, Los Angeles, CA, 4Dalhousie University and Capital Health, Halifax, NS, 5Johns Hopkins Hospital, Baltimore, MD, 6University College London, London, United Kingdom, 7McGill UHC/RVH, Montreal, QC, 8Hanyang University Hospital for Rheumatic Diseases, Seoul, South Korea, 9Hospital Clínic, Barcelona, Spain, 10Hospital de Cruces, Bizkaia, Spain, 11Hospital Virgen del Rocío, Sevilla, Spain, 12Hospital Miguel Servet, Zaragoza, Spain, 13Hospital San Cecilio, Granada, Spain, 14Hospital Son Dureta, Palma de Mallorca, Spain, 15Hospital Carlos Haya, Málaga, Spain, 16Karolinska Institutet, Stockholm, Sweden, 17Istanbul University, Istanbul Medical Faculty, Istanbul, Turkey, 18Northwestern University Feinberg School of Medicine, Chicago, IL, 19Univ of Manitoba, Winnipeg, MB, 20Careggi Hospital- Florence, Florence, Italy, 21University of Szeged, Szeged, Hungary, 22University of Padova, Padova, Italy, 23University of Debrecen Medical and Health Sciences Center, Debrecen, Hungary, 24Rheumatology Unit, Catholic University, Roma, Italy, 25Escola Paulista de Medicina - Universidade Federal de São Paulo, Sao Paulo, Brazil

Variation in the ICAM1-ICAM4-ICAM5 Locus Is Associated with Systemic Lupus Erythematosus Susceptibility in Multiple Ancestry Populations
Kwangwoo Kim*1, and Elizabeth E. Brown* on behalf of PROFILE2, Chan-Bum Choi3, Marta E. Alarcon-Riquelme on behalf of BIOLUPUS4, Jennifer A. Kelly5, Kenneth M. Kaufman5, So-Young Bang3, Hye-Soon Lee3, Taehyeung Kim1, Swapan Nath5, Betty P. Tsao6, Amr H. Sawalha5, Bernardo Pons-Estel on behalf of GENLES7, Timothy J. Vyse on behalf of SLEGEN8, Patrick M. Gaffney on behalf of LLAS25, Carl D. Langefeld9, John B. Harley10, Changwon Kang1, Robert P. Kimberly2 and Sang-Cheol Bae on behalf of Korean Investigators3, 1Korea Advanced Institute of Science and Technology, Daejeon, South Korea, 2University of Alabama at Birmingham, Birmingham, AL, 3Hanyang University Hospital for Rheumatic Diseases, Seoul, South Korea, 4Pfizer-University of Granada-Junta de Andalucía, Grranada, Spain, 5Oklahoma Medical Research Foundation, Oklahoma City, OK, 6David Geffen School of Medicine University of California Los Angeles, Los Angeles, CA, 7Sanatorio Parque, Rosario, Argentina, 8King's College London, Guy's Hospital, London, United Kingdom, 9Wake Forest School of Medicine, Winston-Salem, NC, 10Cincinnati Children's Hospital Medical Center and the US Department of Veterans Affairs Medical Center, Cincinnati, OH

Free Interleukin 18 As a Predictor of Remission and Flare up in Adult-Onset Still’s Disease Patients
Kyong-Hee Jung1, Joo Hyun Lee2, JinJu Kim2, Jin Sook Lee2, Won Park1, Tae-Hwan Kim2 and Dae-Hyun Yoo2, 1Center for Rheumatism, Inha University Hospital, Incheon, South Korea, 2Hanyang University Hospital for Rheumatic Diseases, Seoul, South Korea

Exposure to Environmental Tobacco Smoke and the Risk of Rheumatoid Arthritis Among Nonsmoking Women
So-Young Bang, Hye-Soon Lee, Jae Hoon Kim, Joo-Hyun Lee, Jin Ju Kim, Young Bin Joo and Sang-Cheol Bae, Hanyang University Hospital for Rheumatic Diseases, Seoul, South Korea

Relationships Between Smoking, HLA-DRB1 Risk Alleles and the Fine Specificity of Anti-Citrullinated Peptide Antibodies in Korean Patients with Rheumatoid Arthritis
Benjamin A. Fisher1, So-Young Bang2, Hye-Soon Lee2, Joo-Hyun Lee2, Muslima Chowdhury3, Peter J. Charles4, Patrick Venables5 and Sang-Cheol Bae6, 1Kennedy Institute of Rheumatology, Imperial College London, London, United Kingdom, 2Hanyang University Hospital for Rheumatic Diseases, Seoul, South Korea, 3Imperial College London, London, United Kingdom, 4Kennedy Institute of Rheumatology, Imperial College, London, United Kingdom, London, England, 5Kennedy Institute, Imperial College London, London, United Kingdom, 6Hanyang University Hospital for Rheumatic Diseases, Clinical Research Center for Rheumatoid Arthritis (CRCRA), Seoul, South Korea

Impact of Comorbidities on TNF Inhibitor Persistence in Rheumatoid Arthritis Patients : An Analysis of Korean National Health Insurance Claims Data
Soo-Kyung Cho1, Yoon-Kyoung Sung1, Chan-Bum Choi2, Jae Hoon Kim3, Jin Ju Kim4, Joo-Hyun Lee4, Young Bin Joo4 and Sang-Cheol Bae1, 1Hanyang University Hospital for Rheumatic Diseases, Clinical Research Center for Rheumatoid Arthritis (CRCRA), Seoul, South Korea, 2Hanyang University Hospital for Rheumatic Disease, Clinical Research Center for Rheumatoid Arthritis (CRCRA), Seoul, South Korea, 3Hanyang University Hospital for Rheumatic Disease, Seoul, South Korea, 4Hanyang University Hospital for Rheumatic Diseases, Seoul, South Korea

The Prevalence and Risk Factors of Atlantoaxial Subluxation in Ankylosing Spondylitis
Ji-Seon Lee, Jae Hoon Kim, Jinju Kim, Joo-Hyun Lee and Tae-Hwan Kim, Hanyang University Hospital for Rheumatic Diseases, Seoul, South Korea
Hanyang University Hospital for Rheumatic Diseases, Clinical Research Center for Rheumatoid Arthritis (CRCRA)
Anti-beta2 Glycoprotein I IgA in Systemic Lupus Erythematosus Versus Controls
Ana-Maria Orbai1, Hong Fang1, Joan T. Merrill2, Graciela S. Alarcón3, Caroline Gordon4, Paul R. Fortin5, Ian N. Bruce6, David A. Isenberg7, Daniel J. Wallace8, Ola Nived9, Gunnar K. Sturfelt10, Rosalind Ramsey-Goldman11, Sang-Cheol Bae12, John G. Hanly13, Jorge Sanchez-Guerrero14, Ann E. Clarke15, Cynthia Aranow16, Susan Manzi17, Murray B. Urowitz18, Dafna D. Gladman19, Kenneth C. Kalunian20, Melissa I. Costner21, Laurence S. Magder22, Systemic Lupus International Collaborating Clinics (SLICC)23 and Michelle Petri1, 1Johns Hopkins University School of Medicine, Baltimore, MD, 2Oklahoma Medical Research Foundation, Oklahoma City, OK, 3University of Alabama at Birmingham, Birmingham, AL, 4University of Birmingham, Birmingham, United Kingdom, 5Toronto Western Hospital, Toronto, ON, 6A, Manchester, United Kingdom, 7University College London, London, United Kingdom, 8Cedars-Sinai/UCLA, Los Angeles, CA, 9University Hospital, Lund, Sweden, 10University Hospital Lund, Lund, Sweden, 11Northwestern University Feinberg School of Medicine, Chicago, IL, 12Hanyang University Hospital for Rheumatic Diseases, Clinical Research Center for Rheumatoid Arthritis (CRCRA), Seoul, South Korea, 13Dalhousie University, Halifax, NS, 14Mount Sinai Hospital/University Health Network, Toronto, ON, 15Research Institute of the McGill Univ. Health, Montreal, QC, 16Feinstein Institute for Medical Research, Manhasset, NY, 17Allegheny Singer Research Institute, Pittsburgh, PA, 18Toronto Western Hospital and University of Toronto, Toronto, ON, 19Toronto Western Research Institute, University of Toronto, University Health Network, Toronto, ON, 20UCSD School of Medicine, La Jolla, CA, 21North Dallas Dermatology Assoc, Dallas, TX, 22University of Maryland, Baltimore, MD, 23Chicago

Prevalence and Incidence of Rheumatoid Arthritis in South Korea
Yoon-Kyoung Sung1, Soo-Kyung Cho1, Chan-Bum Choi1, Jae Hoon Kim2, Jin Ju Kim2, Joo-Hyun Lee2, Young Bin Joo2 and Sang-Cheol Bae1, 1Hanyang University Hospital for Rheumatic Diseases, Clinical Research Center for Rheumatoid Arthritis (CRCRA), Seoul, South Korea, 2Hanyang University Hospital for Rheumatic Diseases, Seoul, South Korea

Do Patients with Elderly-Onset Rheumatoid Arthritis Have Severe Functional Disability?
Soo-Kyung Cho1, Yoon-Kyoung Sung1, So-Yeon Park1, Jeeseon Shim2, Chan-Bum Choi3, Hoon-Suk Cha4, Jung-Yoon Choe5, Won-Tae Chung6, Seung-Jae Hong7, Jae Bum Jun8, Tae-Hwan Kim9, Tae-Jong Kim10, Eun-Mi Koh4, Jisoo Lee11, Shin-Seok Lee10, Sung Won Lee6, Wan-sik Uhm8, Dae-Hyun Yoo9, Bo Young Yoon12, Sang-Cheol Bae1 and KORONA investigators13, 1Hanyang University Hospital for Rheumatic Diseases, Clinical Research Center for Rheumatoid Arthritis (CRCRA), Seoul, South Korea, 2Clinical Research Center for Rheumatoid Arthritis (CRCRA), Seoul, South Korea, 3Hanyang University Hospital for Rheumatic Disease, Clinical Research Center for Rheumatoid Arthritis (CRCRA), Seoul, South Korea, 4Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, South Korea, 5Catholic university of Daegu, School of mediine, Daegu, South Korea, 6Dong-A University Hospital, Busan, South Korea, 7Kyung Hee University Hospital, Seoul, South Korea, 8Hanyang University Hospital for Rheumatic Disease, Seoul, South Korea, 9Hanyang University Hospital for Rheumatic Diseases, Seoul, South Korea, 10Chonnam National University Medical School and Hospital, Gwangju, South Korea, 11Ewha Womans University Mokdong Hospital, Seoul, South Korea, 12Inje University Ilsan Paik Hospital, Goyang, South Korea, 13Seoul

What Factors Affect Discordance Between Physicians and Patients in Assessments of Global Health in Rheumatoid Arthritis?
Soo-Kyung Cho1, Yoon-Kyoung Sung1, So-Yeon Park1, Jeeseon Shim2, Chan-Bum Choi3, Hoon-Suk Cha4, Jung-Yoon Choe5, Won-Tae Chung6, Jae Bum Jun7, Tae-Hwan Kim8, Tae-Jong Kim9, Eun-Mi Koh4, Jisoo Lee10, Shin-Seok Lee9, Sung Hoon Park5, Wan-sik Uhm7, Dae-Hyun Yoo8, Bo Young Yoon11, Sang-Cheol Bae1 and KORONA investigators12, 1Hanyang University Hospital for Rheumatic Diseases, Clinical Research Center for Rheumatoid Arthritis (CRCRA), Seoul, South Korea, 2Clinical Research Center for Rheumatoid Arthritis (CRCRA), Seoul, South Korea, 3Hanyang University Hospital for Rheumatic Disease, Clinical Research Center for Rheumatoid Arthritis (CRCRA), Seoul, South Korea, 4Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, South Korea, 5Catholic University of Daegu School of Medicine, Daegu, South Korea, 6Dong-A University, Busan, South Korea, 7Hanyang University Hospital for Rheumatic Disease, Seoul, South Korea, 8Hanyang University Hospital for Rheumatic Diseases, Seoul, South Korea, 9Chonnam National University Medical School and Hospital, Gwangju, South Korea, 10Ewha Womans University Mokdong Hospital, Seoul, South Korea, 11Inje University Ilsan Paik Hospital, Goyang, South Korea, 12Seoul, South Korea

A Prospective Study of Seizures in Systemic Lupus Erythematosus
John G. Hanly1, Murray B. Urowitz2, Li Su3, Caroline Gordon4, Sang-Cheol Bae5, Jorge Sanchez-Guerrero6, Juanita Romero-Diaz7, Daniel Wallace8, Ann Clarke9, Sasha Bernatsky10, E.M. Ginzler11, Joan T. Merrill12, David A. Isenberg13, Anisur Rahman13, M. Petri14, Paul R. Fortin15, Dafna D. Gladman16, Ian N. Bruce17, Kristjan Steinsson18, M.A. Dooley19, Munther A. Khamashta20, Graciela S. Alarcon21, Barri J. Fessler21, Rosalind Ramsey-Goldman22 and Susan Manzi23, 1Dalhousie University, Halifax, NS, 2Toronto Western Hospital and University of Toronto, Toronto, ON, 3MRC Biostatistics Unit, Institute of Public Health, University Forvie Site, Cambridge, UK, Cambridge, United Kingdom, 4University of Birmingham, Birmingham, United Kingdom, 5Hanyang University Hospital for Rheumatic Diseases, Clinical Research Center for Rheumatoid Arthritis (CRCRA), Seoul, South Korea, 6Mount Sinai Hospital/University Health Network, Toronto, ON, 7INCMNSZ, Mexico city, Mexico, 8Cedars-Sinai/UCLA, Los Angeles, CA, 9Montreal General Hospital, Montreal, QC, 10McGill UHC/RVH, Montreal, QC, 11SUNY-Downstate Medical Center, Brooklyn, NY, 12Oklahoma Medical Research Foundation, Oklahoma City, OK, 13University College London, London, United Kingdom, 14Johns Hopkins University School of Medicine, Baltimore, MD, 15Toronto Western Hospital, Toronto, ON, 16Toronto Western Hospital, University of Toronto, Toronto, ON, 17A, Manchester, United Kingdom, 18Landspital Univ Hospital, Reykjavik, Iceland, 19University of North Carolina at Chapel Hill, Chapel Hill, NC, 20Lupus Research Unit, The Rayne Institute, Kings College London School of Medicine, London, United Kingdom, 21University of Alabama at Birmingham, Birmingham, AL, 22Northwestern University Feinberg School of Medicine, Chicago, IL, 23Allegheny Singer Research Institute, Pittsburgh, PA

Predictors of Seizures in Systemic Lupus Erythematosus
John G. Hanly1, Murray B. Urowitz2, Li Su3, Caroline Gordon4, Sang-Cheol Bae5, Jorge Sanchez-Guerrero6, Juanita Romero-Diaz7, Daniel Wallace8, Ann E. Clarke9, Sasha Bernatsky10, E.M. Ginzler11, Joan T. Merrill12, David A. Isenberg13, Anisur Rahman13, M. Petri14, Paul R. Fortin15, Dafna D. Gladman16, Ian N. Bruce17, Kristjan Steinsson18, M.A. Dooley19, Munther A. Khamashta20, Graciela S. Alarcon21, Barri J. Fessler21, Rosalind Ramsey-Goldman22 and Susan Manzi23, 1Dalhousie University and Capital Health, Halifax, NS, 2Toronto Western Hospital and University of Toronto, Toronto, ON, 3MRC Biostatistics Unit, Institute of Public Health, University Forvie Site, Cambridge, UK, Cambridge, United Kingdom, 4University of Birmingham, Birmingham, United Kingdom, 5Hanyang University Hospital for Rheumatic Diseases, Clinical Research Center for Rheumatoid Arthritis (CRCRA), Seoul, South Korea, 6Mount Sinai Hospital/University Health Network, Toronto, ON, 7INCMNSZ, Mexico city, Mexico, 8Cedars-Sinai/UCLA, Los Angeles, CA, 9Research Institute of the McGill Univ. Health, Montreal, QC, 10McGill UHC/RVH, Montreal, QC, 11SUNY-Downstate Medical Center, Brooklyn, NY, 12Oklahoma Medical Research Foundation, Oklahoma City, OK, 13University College London, London, United Kingdom, 14Johns Hopkins University School of Medicine, Baltimore, MD, 15Toronto Western Hospital, Toronto, ON, 16Toronto Western Hospital, University of Toronto, Toronto, ON, 17A, Manchester, United Kingdom, 18Landspital Univ Hospital, Reykjavik, Iceland, 19University of North Carolina at Chapel Hill, Chapel Hill, NC, 20Lupus Research Unit, The Rayne Institute, Kings College London School of Medicine, London, United Kingdom, 21University of Alabama at Birmingham, Birmingham, AL, 22Northwestern University Feinberg School of Medicine, Chicago, IL, 23Allegheny Singer Research Institute, Pittsburgh, PA

Phenotypic Associations of Genetic Susceptibility Loci In Systemic Lupus Erythematosus
Elena Sanchez1, Ajay Nadig1, Bruce C. Richardson2, Barry I. Freedman3, Kenneth Kaufman4, Timothy B. Niewold5, Diane L. Kamen6, Gary S. Gilkeson7, Carl D. Langefeld3, Robert P. Kimberly8, J.T. Merrill1, Juan-Manuel Anaya9, Judith A. James10, Bernardo Pons-Estel11, Javier Martin12, Sang-Cheol Bae13, Kathy L. Moser14, Tomothy J. Vyse15, Lindsey A. Criswell16, Patrick M. Gaffney14, Betty P. Tsao17, Chaim O. Jacob18, John B. Harley19, Marta E. Alarcon-Riquelme on behalf of BIOLUPUS and GENLES20 and Amr H. Sawalha1, 1Oklahoma Medical Research Foundation, Oklahoma City, OK, 2University of Michigan, Ann Arbor, MI, 3Wake Forest University Health Sciences, Winston-Salem, NC, 4Oklahoma Medical Research Foundation, Oklahoma CIty, OK, 5University of Chicago, Chicago, IL, 6Medical University of SC, Charleston, SC, 7Division of Rheumatologyand Immunology, Medical University of South Carolina, Charleston, SC, 8University of Alabama at Birmingham, Birmingham, AL, 9Universidad del Rosario-Corporacion para Investigaciones Biologicas, Bogota, Colombia, 10Oklahoma Medical Research Foundation and Oklahoma University Health Sciences Center, Oklahoma City, OK, 11Rosario, Argentina, 12Instituto de Parasitologia y Biomedicina Lopez-Neyra (CSIC), Granada, Spain, 13Hanyang University Hospital for Rheumatic Diseases, Clinical Research Center for Rheumatoid Arthritis (CRCRA), Seoul, South Korea, 14Arthritis and Clinical Immunology Research Program, Oklahoma Medical Research Foundation, Oklahoma City, OK, 15King's College London, Guy's Hospital, London, United Kingdom, 16University of California San Francisco, San Francisco, CA, 17UCLA School of Medicine, Los Angeles, CA, 18Department of Medicine, Keck School of Medicine, University of Southern California, Los Angeles, CA, 19Cincinnati Children's Hospital Medical Center and the US Department of Veterans Affairs Medical Center, Cincinnati, OH, 20Oklahoma Medical Research Foundation, Center for Genomics and Oncological Research Pfizer-University of Granada-Junta de Andalucia, Oklahoma City, OK

Genetic Associations with Serologic Autoimmunity in a Large Multi-Ancestral Systemic Lupus Erythematosus Cohort
Silvia Kariuki1, Beverly S. Franek1, Akaash A. Kumar1, Marissa Kumabe1, Kenneth M. Kaufman2, Juan-Manuel Anaya3, Marta E. Alarcón-Riquelme4, Sang-Cheol Bae5, Elizabeth E. Brown6, Barry I. Freedman7, Gary S. Gilkeson8, Chaim O. Jacob9, Judith A. James10, Robert P. Kimberly11, Javier Martin12, Joan T. Merrill13, Bernardo Pons-Estel14, Betty P. Tsao15, Timothy J. Vyse16, Carl D. Langefeld7, John B. Harley17, Kathy L. Moser18, Patrick M. Gaffney18, Andrew D. Skol1 and Timothy B. Niewold1, 1University of Chicago, Chicago, IL, 2Arthritis and Clinical Immunology Research Program, Oklahoma Medical Research Foundation and US Department of Veterans Affairs Medical Center, Oklahoma City, OK, 3Universidad del Rosario-Corporacion para Investigaciones Biologicas, Bogota, Colombia, 4Oklahoma Medical Research Foundation and Centro de Genómica e Investigación Oncológica Pfizer-Universidad de Granada-Junta de Andalucía (GENYO), Granada, Spain, on behalf of the BIOLUPUS and GENLES networks, Oklahoma City, OK, 5Hanyang University Hospital for Rheumatic Diseases, Clinical Research Center for Rheumatoid Arthritis (CRCRA), Seoul, South Korea, 6Department of Medicine and Department of Epidemiology, University of Alabama at Birmingham, Birmingham, AL, 7Wake Forest School of Medicine, Winston-Salem, NC, 8Division of Rheumatologyand Immunology, Medical University of South Carolina, Charleston, SC, 9Department of Medicine, Keck School of Medicine, University of Southern California, Los Angeles, CA, 10Oklahoma Medical Research Foundation and Oklahoma University Health Sciences Center, Oklahoma City, OK, 11University of Alabama at Birmingham, Birmingham, AL, 12Instituto de Parasitologia y Biomedicina Lopez-Neyra (CSIC), Granada, Spain, 13Oklahoma Medical Research Foundation, Oklahoma City, OK, 14Sanatorio Parque, Rosario, Argentina, 15David Geffen School of Medicine University of California Los Angeles, Los Angeles, CA, 16Divisions of Genetics and Molecular Medicine and Immunology, King's College London, London, United Kingdom, 17Cincinnati Children's Hospital Medical Center and the US Department of Veterans Affairs Medical Center, Cincinnati, OH, 18Arthritis and Clinical Immunology Research Program, Oklahoma Medical Research Foundation, Oklahoma City, OK

A Single Risk Haplotype in the Region of UBE2L3 Is Associated with Systemic Lupus Erythematosus in Multiple Ethnic Populations
Shaofeng Wang1, Indra Adrianto1, Graham B. Wiley1, Kenneth M. Kaufman2, Juan-Manuel Anaya3, Marta E. Alarcón-Riquelme on behalf of the BIOLUPUS and GENLES networ4, Sang-Cheol Bae5, Elizabeth E. Brown6, Barry I. Freedman7, Gary S. Gilkeson8, Chaim O. Jacob9, Judith A. James10, Robert P. Kimberly on behalf of PROFILE investigators11, Javier Martin12, Joan T. Merrill1, Timothy B. Niewold13, Bernardo Pons-Estel14, Betty P. Tsao15, Tomothy J. Vyse16, Carl D. Langefeld7, John B. Harley17, Edward Wakeland18, Kathy L. Moser19, Courtney G. Montgomery1 and Patrick M. Gaffney19, 1Oklahoma Medical Research Foundation, Oklahoma City, OK, 2Arthritis and Clinical Immunology Research Program, Oklahoma Medical Research Foundation and US Department of Veterans Affairs Medical Center, Oklahoma City, OK, 3Universidad del Rosario-Corporacion para Investigaciones Biologicas, Bogota, Colombia, 4Oklahoma Medical Research Foundation; Center for Genomics and Oncological Research, Oklahoma City; Granada, Spain, OK, 5Hanyang University Hospital for Rheumatic Diseases, Clinical Research Center for Rheumatoid Arthritis (CRCRA), Seoul, South Korea, 6University of Alabama at Birmingham, Birmingham, AL, 7Wake Forest School of Medicine, Winston-Salem, NC, 8Division of Rheumatologyand Immunology, Medical University of South Carolina, Charleston, SC, 9Department of Medicine, Keck School of Medicine, University of Southern California, Los Angeles, CA, 10Oklahoma Medical Research Foundation and Oklahoma University Health Sciences Center, Oklahoma City, OK, 11Department of Medicine, University of Alabama at Birmingham, Birmingham, AL, 12Instituto de Parasitologia y Biomedicina Lopez-Neyra (CSIC), Granada, Spain, 13University of Chicago, Chicago, IL, 14Sanatorio Parque, Rosario, Argentina, 15David Geffen School of Medicine University of California Los Angeles, Los Angeles, CA, 16King's College London, Guy's Hospital, London, United Kingdom, 17Cincinnati Children's Hospital Medical Center and the US Department of Veterans Affairs Medical Center, Cincinnati, OH, 18Univ of Texas SW Med Ctr, Dallas, TX, 19Arthritis and Clinical Immunology Research Program, Oklahoma Medical Research Foundation, Oklahoma City, OK

A Functional Haplotype in the Region of TNIP1 Is Associated with Systemic Lupus Erythematosus in Multiple Populations
Indra Adrianto1, Graham B. Wiley1, Shaofeng Wang1, Kenneth M. Kaufman2, Juan-Manuel Anaya3, Marta E. Alarcón-Riquelme on behalf of BIOLUPUS and GENLES networks4, Sang-Cheol Bae5, Elizabeth E. Brown for PROFILE6, Barry I. Freedman7, Gary S. Gilkeson8, Chaim O. Jacob9, Judith A. James10, Robert P. Kimberly6, Javier Martin11, Joan T. Merrill1, Timothy B. Niewold12, Betty P. Tsao13, Timothy J. Vyse14, Carl D. Langefeld7, John B. Harley15, Edward K. Wakeland16, Kathy L. Moser17, Courtney G. Montgomery1 and Patrick M. Gaffney17, 1Oklahoma Medical Research Foundation, Oklahoma City, OK, 2Arthritis and Clinical Immunology Research Program, Oklahoma Medical Research Foundation and US Department of Veterans Affairs Medical Center, Oklahoma City, OK, 3Universidad del Rosario-Corporacion para Investigaciones Biologicas, Bogota, Colombia, 4Oklahoma Medical Research Foundation and Centro de Genómica e Investigación Oncológica Pfizer-Universidad de Granada-Junta de Andalucía (GENYO), Granada, Spain, Oklahoma City, OK, 5Hanyang University Hospital for Rheumatic Diseases, Clinical Research Center for Rheumatoid Arthritis (CRCRA), Seoul, South Korea, 6University of Alabama at Birmingham, Birmingham, AL, 7Wake Forest School of Medicine, Winston-Salem, NC, 8Division of Rheumatologyand Immunology, Medical University of South Carolina, Charleston, SC, 9Department of Medicine, Keck School of Medicine, University of Southern California, Los Angeles, CA, 10Oklahoma Medical Research Foundation and Oklahoma University Health Sciences Center, Oklahoma City, OK, 11Instituto de Parasitologia y Biomedicina Lopez-Neyra (CSIC), Granada, Spain, 12University of Chicago, Chicago, IL, 13David Geffen School of Medicine University of California Los Angeles, Los Angeles, CA, 14Divisions of Genetics and Molecular Medicine and Immunology, King's College London, London, United Kingdom, 15Cincinnati Children's Hospital Medical Center and the US Department of Veterans Affairs Medical Center, Cincinnati, OH, 16Univ of Texas SW Med Ctr, Dallas, TX, 17Arthritis and Clinical Immunology Research Program, Oklahoma Medical Research Foundation, Oklahoma City, OK

SLE-Risk Alleles of SNPs in the NMNAT2/SMG7 Region Are Associated with Lower mRNA Levels of SMG7
Jian Zhao1, Daisuke Sakurai1, Yun Deng1, Andrea L. Sestak2, Carl D. Langefeld3, Kenneth M. Kaufman4, Jennifer A. Kelly5, Patrick M. Gaffney6, Kathy L. Moser6, Marta E. Alarcón-Riquelme on behalf of BIOLUPUS and GENLES network7, John B. Harley8, Sang-Cheol Bae9, Timothy J. Vyse10, Chaim O. Jacob11, Robert P. Kimberly on behalf of PROFILE investigators12, Lindsey A. Criswell13, Judith A. James14, Gary S. Gilkeson15, Juan-Manuel Anaya16, Deh-Ming Chang17, Yeong W. Song18, Jennifer M. Grossman19, Bevra H. Hahn19, Rita M. Cantor20 and Betty P. Tsao1, 1David Geffen School of Medicine University of California Los Angeles, Los Angeles, CA, 2University of Oklahoma Health Sciences Center, Oklahoma City, OK, 3Wake Forest University Health Sciences, Winston-Salem, NC, 4US Department of Veterans Affairs Medical Center and Oklahoma Medical Research Foundation, Oklahoma City, OK, 5Oklahoma Medical Research Foundation, Oklahoma City, OK, 6Arthritis and Clinical Immunology Research Program, Oklahoma Medical Research Foundation, Oklahoma City, OK, 7Centro de Genómica e Investigación Oncológica Pfizer-Universidad de Granada-Junta de Andalucía (GENYO), Granada, Spain and Oklahoma Medical Research Foundation, Oklahoma City, OK, 8Cincinnati Children's Hospital Medical Center and the US Department of Veterans Affairs Medical Center, Cincinnati, OH, 9Hanyang University Hospital for Rheumatic Diseases, Clinical Research Center for Rheumatoid Arthritis (CRCRA), Seoul, South Korea, 10Divisions of Genetics and Molecular Medicine and Immunology, King's College London, London, United Kingdom, 11Keck School of Medicine University of Southern California, Los Angeles, CA, 12University of Alabama Birmingham, Birmingham, AL, 13Rosalind Russell Medical Research Center for Arthritis, Department of Medicine, University of California San Francisco, San Francisco, CA, 14Department of Medicine, University of Oklahoma Health Sciences Center and Oklahoma Medical Research Foundation, Oklahoma City, OK, 15Division of Rheumatologyand Immunology, Medical University of South Carolina, Charleston, SC, 16Universidad del Rosario-Corporacion para Investigaciones Biologicas, Bogota, Colombia, 17National Defense Medical Center, Taipei, 18Seoul National University, Seoul, 19UCLA David Geffen School of Medicine, Los Angeles, CA, 20University of California Los Angeles, Los Angeles, CA

Fine Mapping of Xq28: Both MECP2/IRAK1 and NAA10/RENBP Contribute to Risk for SLE in Multiple Ancestral Groups
Kenneth M. Kaufman1, Jennifer A. Kelly2, Travis Hughes2, Adam Adler2, Elena Sanchez2, Joshua O. Ojwang2, Carl D. Langefeld3, Julie T. Ziegler3, Judith A. James4, Elizabeth E. Brown5, Robert P. Kimberly6, Jeffrey C. Edberg7, Lindsey A. Criswell8, Deh-Ming Chang9, Gary S. Gilkeson10, Timothy B. Niewold11, Sang-Cheol Bae12, Marta E. Alarcón-Riquelme13, Chaim O. Jacob14, Kathy L. Moser15, Patrick M. Gaffney15, John B. Harley16, Amr H. Sawalha2 and Betty P. Tsao17, 1Arthritis and Clinical Immunology Research Program, Oklahoma Medical Research Foundation and US Department of Veterans Affairs Medical Center, Oklahoma City, OK, 2Oklahoma Medical Research Foundation, Oklahoma City, OK, 3Wake Forest University Health Sciences, Winston-Salem, NC, 4Oklahoma Medical Research Foundation and Oklahoma University Health Sciences Center, Oklahoma City, OK, 5Department of Medicine and Department of Epidemiology, University of Alabama at Birmingham, Birmingham, AL, 6University of Alabama at Birmingham, Birmingham, AL, 7Department of Medicine, University of Alabama at Birmingham, Birmingham, AL, 8University of California San Francisco, San Francisco, CA, 9National Defense Medical Center, Taipei, 10Division of Rheumatologyand Immunology, Medical University of South Carolina, Charleston, SC, 11University of Chicago, Chicago, IL, 12Hanyang University Hospital for Rheumatic Diseases, Clinical Research Center for Rheumatoid Arthritis (CRCRA), Seoul, South Korea, 13Oklahoma Medical Research Foundation and Centro de Genómica e Investigación Oncológica Pfizer-Universidad de Granada-Junta de Andalucía (GENYO), Granada, Spain, on behalf of the BIOLUPUS and GENLES networks, Oklahoma City, OK, 14Department of Medicine, Keck School of Medicine, University of Southern California, Los Angeles, CA, 15Arthritis and Clinical Immunology Research Program, Oklahoma Medical Research Foundation, Oklahoma City, OK, 16Cincinnati Children's Hospital Medical Center and the US Department of Veterans Affairs Medical Center, Cincinnati, OH, 17David Geffen School of Medicine University of California Los Angeles, Los Angeles, CA

Anti-C1q Antibody in Systemic Lupus Erythematosus
Ana-Maria Orbai1, Gunnar K. Sturfelt2, Ola Nived3, Hong Fang1, Graciela S. Alarcón4, Caroline Gordon5, Joan T. Merrill6, Paul R. Fortin7, Ian N. Bruce8, David A. Isenberg9, Daniel J. Wallace10, Rosalind Ramsey-Goldman11, Sang-Cheol Bae12, John G. Hanly13, Jorge Sanchez-Guerrero14, Ann E. Clarke15, Cynthia Aranow16, Susan Manzi17, Murray B. Urowitz18, Dafna D. Gladman19, Kenneth C. Kalunian20, Melissa I. Costner21, Laurence S. Magder22, Systemic Lupus International Collaborating Clinics (SLICC)23 and Michelle Petri1, 1Johns Hopkins University School of Medicine, Baltimore, MD, 2University Hospital Lund, Lund, Sweden, 3University Hospital, Lund, Sweden, 4University of Alabama at Birmingham, Birmingham, AL, 5University of Birmingham, Birmingham, United Kingdom, 6Oklahoma Medical Research Foundation, Oklahoma City, OK, 7Toronto Western Hospital, Toronto, ON, 8A, Manchester, United Kingdom, 9University College London, London, United Kingdom, 10Cedars-Sinai/UCLA, Los Angeles, CA, 11Northwestern University Feinberg School of Medicine, Chicago, IL, 12Hanyang University Hospital for Rheumatic Diseases, Clinical Research Center for Rheumatoid Arthritis (CRCRA), Seoul, South Korea, 13Dalhousie University, Halifax, NS, 14Mount Sinai Hospital/University Health Network, Toronto, ON, 15Research Institute of the McGill Univ. Health, Montreal, QC, 16Feinstein Institute for Medical Research, Manhasset, NY, 17Allegheny Singer Research Institute, Pittsburgh, PA, 18Toronto Western Hospital and University of Toronto, Toronto, ON, 19Toronto Western Research Institute, University of Toronto, University Health Network, Toronto, ON, 20UCSD School of Medicine, La Jolla, CA, 21North Dallas Dermatology Assoc, Dallas, TX, 22University of Maryland, Baltimore, MD, 23Chicago

Prevalence of Direct Coombs Test in Systemic Lupus Erythematosus.  Clinical and Immunologic Associations
Ana-Maria Orbai1, Hong Fang1, Graciela S. Alarcón2, Caroline Gordon3, Joan T. Merrill4, Paul R. Fortin5, Ian N. Bruce6, David A. Isenberg7, Daniel J. Wallace8, Ola Nived9, Gunnar K. Sturfelt10, Rosalind Ramsey-Goldman11, Sang-Cheol Bae12, John G. Hanly13, Jorge Sanchez-Guerrero14, Ann E. Clarke15, Cynthia Aranow16, Susan Manzi17, Murray B. Urowitz18, Dafna D. Gladman19, Kenneth C. Kalunian20, Melissa I. Costner21, Laurence S. Magder22, Systemic Lupus International Collaborating Clinics (SLICC)23 and Michelle Petri1, 1Johns Hopkins University School of Medicine, Baltimore, MD, 2University of Alabama at Birmingham, Birmingham, AL, 3University of Birmingham, Birmingham, United Kingdom, 4Oklahoma Medical Research Foundation, Oklahoma City, OK, 5Toronto Western Hospital, Toronto, ON, 6A, Manchester, United Kingdom, 7University College London, London, United Kingdom, 8Cedars-Sinai/UCLA, Los Angeles, CA, 9University Hospital, Lund, Sweden, 10University Hospital Lund, Lund, Sweden, 11Northwestern University Feinberg School of Medicine, Chicago, IL, 12Hanyang University Hospital for Rheumatic Diseases, Clinical Research Center for Rheumatoid Arthritis (CRCRA), Seoul, South Korea, 13Dalhousie University, Halifax, NS, 14Mount Sinai Hospital/University Health Network, Toronto, ON, 15Research Institute of the McGill Univ. Health, Montreal, QC, 16Feinstein Institute for Medical Research, Manhasset, NY, 17Allegheny Singer Research Institute, Pittsburgh, PA, 18Toronto Western Hospital and University of Toronto, Toronto, ON, 19Toronto Western Research Institute, University of Toronto, University Health Network, Toronto, ON, 20UCSD School of Medicine, La Jolla, CA, 21North Dallas Dermatology Assoc, Dallas, TX, 22University of Maryland, Baltimore, MD, 23Chicago

Derivation and Validation of Systemic Lupus International Collaborating Clinics Classification Criteria for Systemic Lupus Erythematosus
Michelle Petri1, Ana-Maria Orbai1, Graciela S. Alarcón2, Caroline Gordon3, Joan T. Merrill4, Paul R. Fortin5, Ian N. Bruce6, David A. Isenberg7, Daniel J. Wallace8, Ola Nived9, Gunnar K. Sturfelt10, Rosalind Ramsey-Goldman11, Sang-Cheol Bae12, John G. Hanly13, Jorge Sanchez-Guerrero14, Ann E. Clarke15, Cynthia Aranow16, Susan Manzi17, Murray B. Urowitz18, Dafna D. Gladman19, Kenneth C. Kalunian20, Melissa I. Costner21, Hong Fang1, Systemic Lupus International Collaborating Clinics (SLICC)22 and Laurence S. Magder23, 1Johns Hopkins University School of Medicine, Baltimore, MD, 2University of Alabama at Birmingham, Birmingham, AL, 3University of Birmingham, Birmingham, United Kingdom, 4Oklahoma Medical Research Foundation, Oklahoma City, OK, 5Toronto Western Hospital, Toronto, ON, 6The University of Manchester, Manchester, United Kingdom, 7University College London, London, United Kingdom, 8Cedars-Sinai/UCLA, Los Angeles, CA, 9University Hospital, Lund, Sweden, 10University Hospital Lund, Lund, Sweden, 11Northwestern University, Chicago, IL, 12Hanyang University Hospital for Rheumatic Diseases, Clinical Research Center for Rheumatoid Arthritis (CRCRA), Seoul, South Korea, 13Dalhousie University and Capital Health, Halifax, NS, 14Mount Sinai Hospital/University Health Network, Toronto, ON, 15Research Institute of the McGill Univ. Health, Montreal, QC, 16Feinstein Institute for Medical Research, Manhasset, NY, 17Allegheny Singer Research Institute, Pittsburgh, PA, 18Toronto Western Hospital and University of Toronto, Toronto, ON, 19Toronto Western Research Institute, University of Toronto, University Health Network, Toronto, ON, 20UCSD School of Medicine, La Jolla, CA, 21North Dallas Dermatology Assoc, Dallas, TX, 22Chicago, 23University of Maryland, Baltimore, MD

Relationships Between Smoking, HLA-DRB1 Risk Alleles and the Fine Specificity of Anti-Citrullinated Peptide Antibodies in Korean Patients with Rheumatoid Arthritis
Benjamin A. Fisher1, So-Young Bang2, Hye-Soon Lee2, Joo-Hyun Lee2, Muslima Chowdhury3, Peter J. Charles4, Patrick Venables5 and Sang-Cheol Bae6, 1Kennedy Institute of Rheumatology, Imperial College London, London, United Kingdom, 2Hanyang University Hospital for Rheumatic Diseases, Seoul, South Korea, 3Imperial College London, London, United Kingdom, 4Kennedy Institute of Rheumatology, Imperial College, London, United Kingdom, London, England, 5Kennedy Institute, Imperial College London, London, United Kingdom, 6Hanyang University Hospital for Rheumatic Diseases, Clinical Research Center for Rheumatoid Arthritis (CRCRA), Seoul, South Korea

Impact of Comorbidities on TNF Inhibitor Persistence in Rheumatoid Arthritis Patients : An Analysis of Korean National Health Insurance Claims Data
Soo-Kyung Cho1, Yoon-Kyoung Sung1, Chan-Bum Choi2, Jae Hoon Kim3, Jin Ju Kim4, Joo-Hyun Lee4, Young Bin Joo4 and Sang-Cheol Bae1, 1Hanyang University Hospital for Rheumatic Diseases, Clinical Research Center for Rheumatoid Arthritis (CRCRA), Seoul, South Korea, 2Hanyang University Hospital for Rheumatic Disease, Clinical Research Center for Rheumatoid Arthritis (CRCRA), Seoul, South Korea, 3Hanyang University Hospital for Rheumatic Disease, Seoul, South Korea, 4Hanyang University Hospital for Rheumatic Diseases, Seoul, South Korea

A Large-Scale, Multi-Racial Replication Study Identifies Novel Systemic Lupus Erythematosus Susceptibility Loci At IRF8, TMEM39A, and IKZF3/ZPBP2
Christopher J. Lessard1, Indra Adrianto1, John A. Ice1, Jennifer A. Kelly1, He Li1, Graham B. Wiley1, Astrid Rasmussen1, Marta E. Alarcon-Riquelme2, Juan-Manuel Anaya3, Sang-Cheol Bae4, Elizabeth E. Brown for PROFILE5, Chaim O. Jacob6, Judith A. James7, Javier Martin8, Timothy B. Niewold9, Bernardo Pons-Estel10, Betty P. Tsao11, Timothy J. Vyse12, John B. Harley13, Edward Wakeland14, Kenneth M. Kaufman15, Courtney Montgomery1, Carl D. Langefeld16, Patrick M. Gaffney17 and Kathy L. Moser17, 1Oklahoma Medical Research Foundation, Oklahoma City, OK, 2Oklahoma Medical Research Foundation, Center for Genomics and Oncological Research Pfizer-University of Granada-Junta de Andalucia, Oklahoma City, OK, 3Universidad del Rosario-Corporacion para Investigaciones Biologicas, Bogota, Colombia, 4Hanyang University Hospital for Rheumatic Diseases, Clinical Research Center for Rheumatoid Arthritis (CRCRA), Seoul, South Korea, 5University of Alabama at Birmingham, Birmingham, AL, 6Department of Medicine, Keck School of Medicine, University of Southern California, Los Angeles, CA, 7Oklahoma Medical Research Foundation and Oklahoma University Health Sciences Center, Oklahoma City, OK, 8Instituto de Parasitologia y Biomedicina Lopez-Neyra (CSIC), Granada, Spain, 9University of Chicago, Chicago, IL, 10Rosario, Argentina, 11UCLA School of Medicine, Los Angeles, CA, 12Divisions of Genetics and Molecular Medicine and Immunology, King's College London, London, United Kingdom, 13Cincinnati Children's Hospital Medical Center and the US Department of Veterans Affairs Medical Center, Cincinnati, OH, 14Univ of Texas SW Med Ctr, Dallas, TX, 15Arthritis and Clinical Immunology Research Program, Oklahoma Medical Research Foundation and US Department of Veterans Affairs Medical Center, Oklahoma City, OK, 16Wake Forest University Health Sciences, Winston-Salem, NC, 17Arthritis and Clinical Immunology Research Program, Oklahoma Medical Research Foundation, Oklahoma City, OK

Risk Alleles of SLE Associated IL10 SNPs Conferred Differential Binding to Transcription Factors
Daisuke Sakurai1, Jian Zhao1, Yun Deng1, Kenneth Kaufman2, Jennifer A. Kelly3, Robert P. Kimberly on behalf of PROFILE investigators4, Marta E. Alarcón-Riquelme on behalf of the BIOLUPUS and GENLES networ5, John B. Harley6, Sang-Cheol Bae7, Chaim O. Jacob8, Timothy J. Vyse9, Timothy B. Niewold10, Patrick M. Gaffney11, Kathy L. Moser11, Judith A. James12, Gary S. Gilkeson13, Diane L. Kamen14, Carl D. Langefeld15, Deh-Ming Chang16, Yeong Wook Song17, Chack-Yung Yu18, Jennifer M. Grossman19, Rita M. Cantor20, Bevra H. Hahn19 and Betty P. Tsao1, 1David Geffen School of Medicine University of California Los Angeles, Los Angeles, CA, 2Oklahoma Medical Research Foundation, Oklahoma CIty, OK, 3Oklahoma Medical Research Foundation, Oklahoma City, OK, 4Department of Medicine, University of Alabama at Birmingham, Birmingham, AL, 5Oklahoma Medical Research Foundation; Center for Genomics and Oncological Research, Oklahoma City; Granada, Spain, OK, 6Cincinnati Children's Hospital Medical Center and the US Department of Veterans Affairs Medical Center, Cincinnati, OH, 7Hanyang University Hospital for Rheumatic Diseases, Clinical Research Center for Rheumatoid Arthritis (CRCRA), Seoul, South Korea, 8Department of Medicine, Keck School of Medicine, University of Southern California, Los Angeles, CA, 9Divisions of Genetics and Molecular Medicine and Immunology, King's College London, London, United Kingdom, 10University of Chicago, Chicago, IL, 11Arthritis and Clinical Immunology Research Program, Oklahoma Medical Research Foundation, Oklahoma City, OK, 12Oklahoma Medical Research Foundation and Oklahoma University Health Sciences Center, Oklahoma City, OK, 13Division of Rheumatologyand Immunology, Medical University of South Carolina, Charleston, SC, 14Medical University of SC, Charleston, SC, 15Wake Forest University Health Sciences, Winston-Salem, NC, 16National Defense Medical Center, Taipei, 17Seoul National University College of Medicine, Seoul, South Korea, 187Center for Molecular and Human Genetics, The Research Institute at Nationwide Children's Hospital and The Ohio State University, Columbus, OH, 19UCLA David Geffen School of Medicine, Los Angeles, CA, 20University of California Los Angeles, Los Angeles, CA
Hanynag University
Association Between Clinical Factors and Radiographic Severity in Ankylosing Spondylitis
Tae-Jong Kim, Chonnam National University Medical School and Hospital, Gwangju, South Korea, Seung-Hun Lee, South Korea, Kyung-Bin Joo, Hanynag University, Seoul, South Korea and Tae-Hwan Kim, Hanyang University Hospital for Rheumatic Diseases, Seoul, South Korea
Harbor UCLA Medical Center
Spanish LupusPRO: Cross Cultural Validation Study for Lupus
Meenakshi Jolly1, Joel A. Block1, Rachel A. Mikolaitis1, Daniel Wallace2, Sergio Duran-Barragán3, Ana M. Bertoli4, Sergio Toloza5, Ivana Blazevic6, Luis M. Vila7, Dilrukshie Cooray8, Emmanuel P. Katsaros9, Karina Marianne D. Torralba10, Michael H. Weisman11 and Graciela S. Alarcon12, 1Rush University Medical Center, Chicago, IL, 2Cedars-Sinai/UCLA, Los Angeles, CA, 3UIECD, Guadalajara, Mexico, Guadalajara, Mexico, 4Instituto Reumatológico Strusberg, Cordoba, Cordoba, Argentina, 5Hospital San Juan Bautista, Catamarca, Argentina, 6University of Buenos Aires, Buenos Aries, Argentina, 7University of PuertoRico Medical Sciences Campus, San Juan, PR, 8Harbor UCLA Medical Center, Torrance, CA, 9Loma Linda Univ, Loma Linda, CA, 10USC Keck Schl of Medicine, Los Angeles, CA, 11Cedars-Sinai Medical Center, Los Angeles, CA, 12University of Alabama at Birmingham, Birmingham, AL

The Effect of Patient Reported Pain on Disability Is Partially Mediated Through Depression in Vulnerable United States Hispanics with Rheumatoid Arthritis
Soha Dolatabadi1, Rosalinda C. Moran2, Galen Cook-Wiens1, Ning Li1, Michael H. Weisman3, Perry M. Nicassio4 and George A. Karpouzas5, 1Cedars Sinai Medical Center, Los Angeles, CA, 2Harbor UCLA Medical Center, Carson, CA, 3Cedars-Sinai Medical Center, Los Angeles, CA, 4UCLA, Los Angeles, CA, 5Harbor-UCLA, Torrance, CA

Longitudinal Determinants of Disability in Vulnerable United States Hispanics with Rheumatoid Arthritis
George A. Karpouzas1, Soha Dolatabadi2, Ning Li2, Rosalinda C. Moran3, Perry M. Nicassio4 and Michael H. Weisman5, 1Harbor-UCLA, Torrance, CA, 2Cedars Sinai Medical Center, Los Angeles, CA, 3Harbor UCLA Medical Center, Carson, CA, 4UCLA, Los Angeles, CA, 5Cedars-Sinai Medical Center, Los Angeles, CA

The Role of Pain and Depression in Self-Reported Fatigue/Energy in Systemic Lupus Erythematosus
Feridey N. Carr1, Perry M. Nicassio2, Dilrukshie Cooray3, Ioana Moldovan4, Emmanuel P. Katsaros5, Karina D. Torralba6, Shuntaro Shinada7, Meenakshi Jolly8, Mariko L. Ishimori9, Alisa L. Wilson9, Daniel J. Wallace10 and Michael H. Weisman11, 1California School of Professional Psychology at Alliant International University - Los Angeles, Alhambra, CA, 2UCLA, Los Angeles, CA, 3Harbor UCLA Medical Center, Torrance, CA, 4Loma Linda Univ Medical Center, Loma Linda, CA, 5Loma Linda Univ, Loma Linda, CA, 6University of Southern California-Los Angeles County Medical Center, Los Angeles, CA, 7USC Keck School of Medicine, Los Angeles, CA, 8Rush University Medical Center, Chicago, IL, 9Cedars Sinai Medical Ctr, Los Angeles, CA, 10Cedars-Sinai/UCLA, Los Angeles, CA, 11Cedars-Sinai Medical Center, Los Angeles, CA
Harbor-UCLA
Differential Predictors of Mixed and Fully Calcified Coronary Plaques in Coronary Artery Disease-Naïve Patients with Rheumatoid Arthritis
George A. Karpouzas1, Jennifer Malpeso2, Dong Li2, Panteja Razaeian2, Maria V. Peralta2, Silvia Munoz1 and Matthew Budoff2, 1Harbor-UCLA, Torrance, CA, 2Harbor-UCLA Medical Center, Torrance, CA

Expansion of Intra-Thoracic Adipose Tissue Depots Associate with Prevalence and Burden of Mixed (Vulnerable) Plaques in Coronary Artery Disease-Naïve Patients with Rheumatoid Arthritis
George A. Karpouzas1, Panteja Razaeian2, Jennifer Malpeso2, Dong Li2, Maria V. Peralta2, Silvia Munoz1 and Matthew Budoff2, 1Harbor-UCLA, Torrance, CA, 2Harbor-UCLA Medical Center, Torrance, CA

The Effect of Patient Reported Pain on Disability Is Partially Mediated Through Depression in Vulnerable United States Hispanics with Rheumatoid Arthritis
Soha Dolatabadi1, Rosalinda C. Moran2, Galen Cook-Wiens1, Ning Li1, Michael H. Weisman3, Perry M. Nicassio4 and George A. Karpouzas5, 1Cedars Sinai Medical Center, Los Angeles, CA, 2Harbor UCLA Medical Center, Carson, CA, 3Cedars-Sinai Medical Center, Los Angeles, CA, 4UCLA, Los Angeles, CA, 5Harbor-UCLA, Torrance, CA

Longitudinal Determinants of Disability in Vulnerable United States Hispanics with Rheumatoid Arthritis
George A. Karpouzas1, Soha Dolatabadi2, Ning Li2, Rosalinda C. Moran3, Perry M. Nicassio4 and Michael H. Weisman5, 1Harbor-UCLA, Torrance, CA, 2Cedars Sinai Medical Center, Los Angeles, CA, 3Harbor UCLA Medical Center, Carson, CA, 4UCLA, Los Angeles, CA, 5Cedars-Sinai Medical Center, Los Angeles, CA
Harbor-UCLA Medical Center
Differential Predictors of Mixed and Fully Calcified Coronary Plaques in Coronary Artery Disease-Naïve Patients with Rheumatoid Arthritis
George A. Karpouzas1, Jennifer Malpeso2, Dong Li2, Panteja Razaeian2, Maria V. Peralta2, Silvia Munoz1 and Matthew Budoff2, 1Harbor-UCLA, Torrance, CA, 2Harbor-UCLA Medical Center, Torrance, CA

Expansion of Intra-Thoracic Adipose Tissue Depots Associate with Prevalence and Burden of Mixed (Vulnerable) Plaques in Coronary Artery Disease-Naïve Patients with Rheumatoid Arthritis
George A. Karpouzas1, Panteja Razaeian2, Jennifer Malpeso2, Dong Li2, Maria V. Peralta2, Silvia Munoz1 and Matthew Budoff2, 1Harbor-UCLA, Torrance, CA, 2Harbor-UCLA Medical Center, Torrance, CA
Harold Hamm Oklahoma Diabetes Center, University of Oklahoma Health Science Center
Association of Body Mass Index, Race/Ethnicity and Gender in a Cohort of Systemic Lupus Erythematosus Patients with Diabetes and/or Hypertension
Jonea Lim, Harold Hamm Oklahoma Diabetes Center, University of Oklahoma Health Science Center, Oklahoma City, OK, Nasir Mushtaq, University of Oklahoma Health Science Center College of Public Health, Oklahoma City, OK, Rachna Aggarwal, University of Oklahoma Health Science Center; Oklahoma Medical Research Foundation, OK and R. Hal Scofield, Oklahoma Medical Research Foundation, Oklahoma City, OK
Harris Interactive Inc.
Impact of Systemic Lupus Erythematosus on Employment and Work Productivity in the US
Ellen Sulcs1, Mechele Lee2, Cindy P. Garris3 and Priti M. Jhingran3, 1Harris Interactive Inc., New York, NY, 2Harris Interactive Inc., New York, 3GlaxoSmithKline R&D, Research Triangle Park, NC
Harrogate District Hospital
A Preliminary Report of Remission Induction with Two Therapeutic Strategies with Infliximab or High Dose Intravenous Steroids for the Treatment of Rheumatoid Arthritis
Jackie L. Nam1, Edith Villeneuve2, Philip G. Conaghan3, Elizabeth Hensor4, Helen I. Keen5, Roshan Amarasena6, Andrew K. Gough7, Philip Helliwell3, Ann W. Morgan3, Mark Quinn8, Michael J. Green9, Richard Reece10, Richard Wakefield3 and Paul Emery11, 1NIHR Leeds Musculoskeletal Biomedical Research Unit , LIMM, University of Leeds., Leeds, United Kingdom, 2NIHR-Leeds Musculoskeletal Biomedical Unit, Leeds Institute of Molecular Medicine, University of Leeds, Leeds, United Kingdom, 3NIHR-Leeds Biomedical Research Unit and Leeds Institute of Molecular Medicine, University of Leeds, Leeds, United Kingdom, 4NIHR-Leeds Musculoskeletal Biomedical Research Unit and Leeds Institute of Molecular Medicine, University of Leeds, Leeds, United Kingdom, 5UWA, Perth, Australia, 6Salford Royal Foundation trust, Manchester, United Kingdom, 7Harrogate District Hospital, Harrogate, United Kingdom, 8The York Hospital, York Teaching Hospital NHS Foundation Trust, York, United Kingdom, 9York Teaching Hospital NHS Foundation Trust, Harrogate, United Kingdom, 10University of Leeds, Leeds, United Kingdom, 11Chapel Allerton Hospital, Leeds, United Kingdom

Preliminary Results of a Multicentre Randomised Controlled Trial of Etanercept and Methotrexate to Induce Remission in Patients with Newly Diagnosed Inflammatory Arthritis
Edith Villeneuve, Leeds Institute of Molecular Medicine, Centre Hospitalier de l'Université de Montréal, Montréal, QC, Jackie L. Nam, NIHR Leeds Musculoskeletal Biomedical Research Unit , LIMM, University of Leeds., Leeds, United Kingdom, Elizabeth Hensor, NIHR-Leeds Musculoskeletal Biomedical Research Unit and Leeds Institute of Molecular Medicine, University of Leeds, Leeds, United Kingdom, Richard J. Wakefield, Leeds Institute of Molecular Medicine, University of Leeds and NIHR Leeds Musculoskeletal Biomedical Research Unit, Leeds Teaching Hospitals, Leeds, United Kingdom, Philip G. Conaghan, NIHR-Leeds Biomedical Research Unit and Leeds Institute of Molecular Medicine, University of Leeds, Leeds, United Kingdom, Mike J. Green, York Teaching Hospital NHS Foundation Trust, Harrogate, United Kingdom, Andrew K. Gough, Harrogate District Hospital, Harrogate, United Kingdom, Mark Quinn, The York Hospital, York Teaching Hospital NHS Foundation Trust, York, United Kingdom, Richard J. Reece, University of Birmingham, Birmingham, United Kingdom, Sally R. Cox, SA Pathology / Flinders Medical Centre, Adelaide, Australia and Paul Emery, Chapel Allerton Hospital, Leeds, United Kingdom
Harry S Truman Mem VA Hospital
Are United States Rheumatologists Interested in Using Electronic Mail in Patient Care? Concerns From a National Survey
Gregory Wilson1, Chokkalingam Siva2, Celso Velazquez1, Karen L. Smarr3, John Fresen1 and Marius Petruc1, 1University of Missouri, Columbia, MO, 2Univ of Missouri Sch of Med, Columbia, MO, 3Harry S Truman Mem VA Hospital, Columbia, MO
Harvard Clinical and Translational Science Center
Gene Expression Profiling in a Cohort of 275 European American Sjögren's Syndrome Patients and Controls
Jennifer A. Kelly1, Christopher J. Lessard1, Indra Adrianto1, John A. Ice1, He Li1, Stuart B. Glenn1, Kimberly Hefner2, Evan Glenn Vista3, Donald U. Stone4, Raj Gopalakrishnan5, Glen D. Houston4, David M. Lewis4, Michael Rohrer5, Pamela Hughes5, John B. Harley6, Courtney G. Montgomery1, James Chodosh7, James A. Lessard8, Juan-Manuel Anaya9, Barbara M. Segal10, Nelson L. Rhodus5, Lida Radfar4, M. Bart Frank1, Robert H. Scofield11 and Kathy L. Moser1, 1Oklahoma Medical Research Foundation, Oklahoma City, OK, 2Hefner Eye Care and Optical Center, Oklahoma City, OK, 3University of Santo Tomas, Taguig City, Philippines, 4University of Oklahoma Health Sciences Center, Oklahoma City, OK, 5University of Minnesota, Minneapolis, MN, 6Cincinnati Children's Hospital Medical Center and the US Department of Veterans Affairs Medical Center, Cincinnati, OH, 7Harvard Clinical and Translational Science Center, Boston, MA, 8Valley Bone & Joint Clinic, Grand Forks, ND, 9Universidad del Rosario-Corporacion para Investigaciones Biologicas, Bogota, Colombia, 10Univ of Minnesota, Minneapolis, MN, 11Arthritis and Clinical Immunology Research Program, Oklahoma Medical Research Foundation, US Department of Veterans Affairs Medical Center and Department of Medicine, University of Oklahoma Health Sciences Center, Oklahoma City, OK
Harvard Medical School
A Transforming Growth Factor-β Receptor One Variant Is Associated with Constitutively Decreased Transforming Growth Factor-β Signaling and Risk for Systemic Sclerosis
Monique E. Hinchcliff1, Michael Pennison2, Jacquelyn Zimmerman2, Naresh Bellam2, Qinghua Zeng2, Chiang-Ching Huang1, Richard M. Pope1, Maureen Sadim1, Wendy Wolf3, Jeffrey C. Edberg4, Robert P. Kimberly2, Kui Zhang5, Jun Li5, Nengjun Yi5, Canadian Scleroderma Research Group (CSRG)6, Scleroderma Registry Investigators7, Maureen D. Mayes7, John Varga1 and Boris Pasche2, 1Northwestern Univ Med School, Chicago, IL, 2University of Alabama at Birmingham, Birmingham, AL, 3Harvard Medical School, Boston, MA, 4Department of Medicine, University of Alabama at Birmingham, Birmingham, AL, 5University of Alabama at Birmingham School of Public Health, Birmingham, AL, 6SMBD Jewish General Hospital, Montreal, QC, 7University of Texas Health Science Center at Houston, Houston, TX

Sex-Specific Effects of Segmented Filamentous Bacteria In the Autoimmune-Prone NOD Mouse Strain – Segregation with Diabetes Protection In Females but Not Males
Martin A. Kriegel1, Esen Sefik2, Jonathan A. Hill2, Hsin-Jung Wu2, Christophe Benoist2 and Diane Mathis2, 1Brigham & Women's Hospital/Harvard Medical School, Boston, MA, 2Harvard Medical School, Boston, MA

2011 Hench Lecture: Resolution of Inflammation
Charles Serhan, Harvard Medical School, Boston, MA

Methods for Reducing Confounding
Sebastian Schneeweiss, Harvard Medical School, Boston, MA

Bone Structure and Quality
Mary L. Bouxsein, Harvard Medical School, Boston, MA
Harvard Medical School; Massachusetts General Hospital
Methylprednisolone Modulates MicroRNA and Gene Expression in Human CD4+ T Cells: A Novel Mechanism of Anti-Inflammatory Action
Trevor E. Davis, Floating Hospital for Children at Tufts Medical Center; Beth Israel Deaconess Medical Center, Boston, MA, Katalin Kis-Toth, Beth Israel Deaconess Medical Center, Boston, MA, Attila Szanto, Harvard Medical School; Massachusetts General Hospital, Boston, MA, Laurie C. Miller, Tufts Medical Center, Boston, MA and George C. Tsokos, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA
Harvard School of Public Health
Exposure to Ultraviolet Light and Risk of Developing Rheumatoid Arthritis Among Women in the Nurses' Health Study
Elizabeth V. Arkema1, Kimberly Bertrand1, Francine Laden1, Abrar A. Qureshi2, Elizabeth W. Karlson2 and Karen H. Costenbader2, 1Harvard School of Public Health, Boston, MA, 2Brigham and Women's Hospital, Boston, MA

Does Physical Performance Mediate the Effect of Knee Osteoarthritis and Risk of Indoor and Outdoor Falls in Older Men and Women?
Uyen Sa D. Nguyen1, Yuqing Zhang1, Tyler J. VanderWeele2, Jingbo Niu1, Robert H. Shmerling3, Douglas P. Kiel4, Suzanne G. Leveille5, Carol A. Oatis6 and Marian T. Hannan7, 1Boston University School of Medicine, Boston, MA, 2Harvard School of Public Health, Boston, MA, 3Beth Israel Deaconess Med Ctr, Boston, MA, 4Hebrew Senior Life/Harvard Medical School, Boston, MA, 5University of Massachusetts-Boston, Boston, MA, 6Arcadia University, Glenside, PA, 7Hebrew SeniorLife & Harvard Med Sch, Boston, MA

The Burden of Autoimmunity and Risk for Coronary Artery Disease in Rheumatoid Arthritis
Katherine P. Liao1, Fina Kurreeman1, Raul N. Guzman P.2, Jun Zhang3, Tianxi Cai3, Gang Li1, Grant Duclos1, Namrata Gupta4, Sergey Goryachev5, Vivian Gainer2, Shawn N. Murphy5, Susanne Churchill5, Isaac Kohane1, Elizabeth W. Karlson6 and Robert M. Plenge1, 1Brigham and Women's Hospital, Boston, MA, 2Information Systems, Boston, MA, 3Harvard School of Public Health, Boston, MA, 4The Broad Institute, Cambridge, 5Partners Healthcare Systems, Boston, MA, 6Brigham and Womens Hospital, Boston, MA

The Association of Ambient Air Pollution Exposures and Risk of Rheumatoid Arthritis: Results From the Swedish EIRA Case-Control Study and the US Nurses’ Health Prospective Cohort Study
Jaime E. Hart1, Henrik Källberg2, Francine Laden3, Karen H. Costenbader1, Marie Holmqvist2, Lars Klareskog2, Lars Alfredsson4 and Elizabeth W. Karlson1, 1Brigham and Women's Hospital, Boston, MA, 2Karolinska Institutet, Stockholm, Sweden, 3Harvard School of Public Health, Boston, MA, 4Institute of Environmental Medicine, Unit of Cardiovascular Epidemiology, Karolinska Institutet, Stockholm, Sweden
Harvard University
DMARD Underuse in the Medicare Current Beneficiary Survey: Evidence for Socioeconomic Disparities
Daniel H. Solomon1, John Z. Ayanian2, Bing Lu1, M. Alan Brookhart3, Sebastian Schneeweiss4, Tamara Shaykevich5 and Jeffrey N. Katz5, 1Brigham and Women's Hospital, Boston, MA, 2Brigham and Women's Hospital, 3University of North Carolina, 4Harvard University, Boston, MA, 5Brigham & Womens Hospital, Boston, MA

Impaired Responses to Aspirin in Patients with Systemic Lupus Erythematosus: The Role of Inflammation and Oxidative Stress
Vivian K. Kawai1, Ingrid B. Avalos2, Annette M. Oeser1, John A. Oates1, Ginger L. Milne1, Cecilia P. Chung3 and C. Michael Stein1, 1Vanderbilt University, Nashville, TN, 2Harvard University, Boston, MA, 3Vanderbilt Medical Center, Nashville, TN

New Insights into Bone Remodeling
Dallas Jones, Harvard University, Boston, MA
Harvard University School of Dental Medicine
Anabolic Pathways-BMPs
Vicki Rosen, Harvard University School of Dental Medicine, Boston, MA
Hatta Clinic
Tocilizumab Improves Arterial Stiffness Compared with Abatacept In Patients with TNF Blockers-Resistant Active Rheumatoid Arthritis.An Open Label Randomized Controlled Trial
Kensuke Kume1, Kanzo Amano1, Susumu Yamada1 and Kazuhiko Hatta2, 1Hiroshima Clinic, Hiroshima, Japan, 2Hatta Clinic, Kure, Japan

Hautepierre Strasbourg Hospital University
Reactive Hyperemia Index Is Associated with Macroangiopathy and Lung Involvement in Systemic Scleroderma
Alain Meyer1, Bernard Geny2, Emmanuel Chatelus3, Olivier Rouyer2, Arnaud Theulin4, Christelle Sordet4, Rose-Marie Javier4, Jean Sibilia5 and Jacques-Eric Gottenberg6, 1Hautepierre Strasbourg university, Strasbourg, France, 2Medicine faculty, Strasbourg university, Strasbourg, France, 3Hopital Hautepierre, Strasbourg, France, 4Hautepierre Strasbourg Hospital University, Strasbourg, France, 5CHU Hautepierre, Strasbourg, France, 6Strasbourg University Hospital, Strasbourg, France

Salivary Gland Epithelial Cells Are Capable to Directly Induce the Differentiation of IL-21-Secreting Follicular Helper CD4 T Cells in Primary Sjögren’s Syndrome
Yazhuo Gong1, Ghada Alsaleh2, Emmanuel Chatelus3, Christelle Sordet4, Jean Sibilia5, Dominique Wachsmann1 and Jacques-Eric Gottenberg2, 1EA 44 38, Strasbourg, France, 2Strasbourg University Hospital, Strasbourg, France, 3Hopital Hautepierre, Strasbourg, France, 4Hautepierre Strasbourg Hospital University, Strasbourg, France, 5CHU Hautepierre, Strasbourg, France

Campylobacter Fetus Infection In Three Patients Treated with Rituximab for Rheumatoid Arthritis
Alain Meyer1, Arnaud Theulin2, Emmanuel Chatelus3, Christelle Sordet2, Rose-Marie Javier2, Helene Chifflot4, Jacques-Eric Gottenberg5 and Jean Sibilia6, 1Hautepierre Strasbourg university, Strasbourg, France, 2Hautepierre Strasbourg Hospital University, Strasbourg, France, 3Hopital Hautepierre, Strasbourg, France, 4Hautepierre Strasbourg Hospital University, 67000, France, 5Strasbourg University Hospital, Strasbourg, France, 6Service de rhumatologie, Hôpitaux Universitaires de Strasbourg, Strasbourg, France, Strasbourg, France
Hautepierre Strasbourg university
Reactive Hyperemia Index Is Associated with Macroangiopathy and Lung Involvement in Systemic Scleroderma
Alain Meyer1, Bernard Geny2, Emmanuel Chatelus3, Olivier Rouyer2, Arnaud Theulin4, Christelle Sordet4, Rose-Marie Javier4, Jean Sibilia5 and Jacques-Eric Gottenberg6, 1Hautepierre Strasbourg university, Strasbourg, France, 2Medicine faculty, Strasbourg university, Strasbourg, France, 3Hopital Hautepierre, Strasbourg, France, 4Hautepierre Strasbourg Hospital University, Strasbourg, France, 5CHU Hautepierre, Strasbourg, France, 6Strasbourg University Hospital, Strasbourg, France

Campylobacter Fetus Infection In Three Patients Treated with Rituximab for Rheumatoid Arthritis
Alain Meyer1, Arnaud Theulin2, Emmanuel Chatelus3, Christelle Sordet2, Rose-Marie Javier2, Helene Chifflot4, Jacques-Eric Gottenberg5 and Jean Sibilia6, 1Hautepierre Strasbourg university, Strasbourg, France, 2Hautepierre Strasbourg Hospital University, Strasbourg, France, 3Hopital Hautepierre, Strasbourg, France, 4Hautepierre Strasbourg Hospital University, 67000, France, 5Strasbourg University Hospital, Strasbourg, France, 6Service de rhumatologie, Hôpitaux Universitaires de Strasbourg, Strasbourg, France, Strasbourg, France
Haywood Hospital
Fine-Mapping of Autoimmune Susceptibility Loci Using Immunochip Identifies Novel Susceptibility Loci for Psoriatic Arthritis
John Bowes1, Pauline Ho2, Eleanor Korendowych3, Neil J. McHugh3, Helena Marzo-Ortega4, Jonathon Packham5, Ian N. Bruce1 and Anne Barton1, 1Arthritis Research UK Epidemiology Unit, Manchester Academic Health Science Centre, The University of Manchester, Manchester, United Kingdom, 2Arthritis Research UK, Manchester, United Kingdom, 3Royal National Hospital for Rheumatic Diseases, Bath, United Kingdom, 4University of Leeds, Leeds, United Kingdom, 5Haywood Hospital, Stoke on Trent, United Kingdom
HCMS Group
Costs and Absences Associated with Rheumatoid Arthritis On Work Productivity: A Comparison Between Employees with and without Rheumatoid Arthritis In a United States Population
Nathan L. Kleinman1, Richard A. Brook2, Stephanie E. Kirbach3 and Mary A. Cifaldi3, 1HCMS Group, Cheyenne, WY, 2The JeSTARx Group, Newfoundland, NJ, 3Abbott Laboratories, Abbott Park, IL
Health and Human Services
Theories on Sex Disparities in Autoimmune Disease: From Estrogen to the X Chromosome
Cherie L. Butts, Health and Human Services, Bethesda, MD
Health Care and Outcomes Research, Toronto Western Research Institute
Organization of Care Delivery for People with Arthritis: Models and Processes
A. M. Davis, Health Care and Outcomes Research, Toronto Western Research Institute; Departments of Rehabilitation Science and Health Policy, Management and Evaluation, University of Toronto, Toronto, ON, C. Cott, Health Care and Outcomes Research, Toronto Western Research Institute; Departments of Physical Therapy and Rehabilitation Science, University of Toronto, Toronto, ON, L. Li, Arthritis Centre of Canada and Department of Physical Therapy, University of British Columbia, Vancouver, BC, M. Landry, Departments of Physical Therapy and Rehabilitation Science, University of Toronto, Toronto, ON, A. Jones, Departments of Physical Therapy and School of Public Health, University of Alberta, Edmonton, AB, R. Wong, Health Care and Outcomes Research, Toronto Western Research Institute, Toronto, ON, C. Frank, Alberta Bone and Joint Institute and Department of Surgery, University of Calgary, Calgary, AB, L. Bergeron, Canadian Arthritis Patient Alliance, Ottawa, ON, R. Birtwhistle, Centre for Studies in Primary Care and Family Medicine and Community Health and Epidemiology, Queen's University, Kingston, ON and E. M. Badley, Health Care and Outcomes Research, Toronto Western Research Institute; Dalla Lana School of Public Health, University of Toronto, Toronto, ON

Improvement 3 to 12 Months Post Hip and Knee Replacement: Implications for Rehabilitation
A. M. Davis, Health Care and Outcomes Research, Toronto Western Research Institute; Departments of Rehabilitation Science and Health Policy, Management and Evaluation, University of Toronto, Toronto, ON, A. V. Perruccio, Department of Orthopedic Surgery and The Arthritis Program, Toronto Western Hospital, Toronto, ON, S. Ibrahim, Institute for Work and Health, Toronto, ON, S. Hogg-Johnson, Institute for Work and Health, and Dalla Lana School of Public Health, University of Toronto, Toronto, ON, R. Wong, Health Care and Outcomes Research, Toronto Western Research Institute, Toronto, ON, E. Schemitsch, Division of Orthopaedics, University of Toronto and St. Michael's, Toronto, ON, N. N. Mahomed, Division of Orthopaedics, University of Toronto and The Arthritis Program, Toronto Western Hospital, Toronto, ON, J. Flannery, Department of Physiatry, University of Toronto and Toronto Rehabilitation Institute, Toronto, ON and E. M. Badley, Health Care and Outcomes Research, Toronto Western Research Institute; Dalla Lana School of Public Health, University of Toronto, Toronto, ON
Health Care and Outcomes Research, Toronto Western Research Institute; Dalla Lana School of Public Health, University of Toronto
Risk of Acute Myocardial Infarction Associated with Arthritis: A Systematic Review of Observational Studies
Orit Schieir, University of Toronto, Toronto, ON, Cedomir Tosevski, Toronto Western Research Institute, Toronto, ON and E. M. Badley, Health Care and Outcomes Research, Toronto Western Research Institute; Dalla Lana School of Public Health, University of Toronto, Toronto, ON

Trajectory of Weight Associated with Arthritis: A Population-Based Longitudinal Cohort Analysis
Orit Schieir, University of Toronto, Toronto, ON, S. Hogg-Johnson, Institute for Work and Health, and Dalla Lana School of Public Health, University of Toronto, Toronto, ON and E. M. Badley, Health Care and Outcomes Research, Toronto Western Research Institute; Dalla Lana School of Public Health, University of Toronto, Toronto, ON

Predictors of Suboptimal Patient Outcome Following Total Joint Arthroplasty
Gillian A. Hawker1, Ruth Croxford2, A. M. Davis3, Sheila Dunn1, Joy G. Elkayam1, Melissa R. French1, M. A. Gignac4, Susan B. Jaglal5 and Joanna Sale5, 1Women's College Hospital, Toronto, ON, 2Institute for Clinical and Evaluative Science, Toronto, ON, 3Health Care and Outcomes Research, Toronto Western Research Institute; Departments of Rehabilitation Science and Health Policy, Management and Evaluation, University of Toronto, Toronto, ON, 4Health Care and Outcomes Research, Toronto Western Research Institute; Dalla Lana School of Public Health, University of Toronto, Toronto, ON, 5University of Toronto, Toronto, ON

A Population-Based Study Comparing the Impact of Arthritis and Chronic Joint Symptoms: Are There Implications for Arthritis Education and Health Care?
Mayilee Canizares, Toronto Western Research Institute, Toronto, ON and E. M. Badley, Health Care and Outcomes Research, Toronto Western Research Institute; Dalla Lana School of Public Health, University of Toronto, Toronto, ON

Organization of Care Delivery for People with Arthritis: Models and Processes
A. M. Davis, Health Care and Outcomes Research, Toronto Western Research Institute; Departments of Rehabilitation Science and Health Policy, Management and Evaluation, University of Toronto, Toronto, ON, C. Cott, Health Care and Outcomes Research, Toronto Western Research Institute; Departments of Physical Therapy and Rehabilitation Science, University of Toronto, Toronto, ON, L. Li, Arthritis Centre of Canada and Department of Physical Therapy, University of British Columbia, Vancouver, BC, M. Landry, Departments of Physical Therapy and Rehabilitation Science, University of Toronto, Toronto, ON, A. Jones, Departments of Physical Therapy and School of Public Health, University of Alberta, Edmonton, AB, R. Wong, Health Care and Outcomes Research, Toronto Western Research Institute, Toronto, ON, C. Frank, Alberta Bone and Joint Institute and Department of Surgery, University of Calgary, Calgary, AB, L. Bergeron, Canadian Arthritis Patient Alliance, Ottawa, ON, R. Birtwhistle, Centre for Studies in Primary Care and Family Medicine and Community Health and Epidemiology, Queen's University, Kingston, ON and E. M. Badley, Health Care and Outcomes Research, Toronto Western Research Institute; Dalla Lana School of Public Health, University of Toronto, Toronto, ON

The Workplace Activity Limitations Among Lupus Patients
Ali Al-Dhanhani, UAE University, Al Ain, United Arab Emirates, M. A. Gignac, Health Care and Outcomes Research, Toronto Western Research Institute; Dalla Lana School of Public Health, University of Toronto, Toronto, ON, Dorcas E. Beaton, Ontario Workers Comp Institute, Toronto, ON, Jiandong Su, The Toronto Western Hospital, Toronto, ON and Paul R. Fortin, Toronto Western Hospital, Toronto, ON

Tool for Patient Selection to Optimize Patient-Reported Outcomes Following Total Joint Arthroplasty
Gillian A. Hawker1, Ruth Croxford2, A. M. Davis3, Sheila Dunn1, Joy G. Elkayam1, Melissa R. French1, M. A. Gignac4, Susan B. Jaglal5 and Joanna Sale5, 1Women's College Hospital, Toronto, ON, 2Institute for Clinical and Evaluative Science, Toronto, 3Health Care and Outcomes Research, Toronto Western Research Institute; Departments of Rehabilitation Science and Health Policy, Management and Evaluation, University of Toronto, Toronto, ON, 4Health Care and Outcomes Research, Toronto Western Research Institute; Dalla Lana School of Public Health, University of Toronto, Toronto, ON, 5University of Toronto, Toronto, ON

Improvement 3 to 12 Months Post Hip and Knee Replacement: Implications for Rehabilitation
A. M. Davis, Health Care and Outcomes Research, Toronto Western Research Institute; Departments of Rehabilitation Science and Health Policy, Management and Evaluation, University of Toronto, Toronto, ON, A. V. Perruccio, Department of Orthopedic Surgery and The Arthritis Program, Toronto Western Hospital, Toronto, ON, S. Ibrahim, Institute for Work and Health, Toronto, ON, S. Hogg-Johnson, Institute for Work and Health, and Dalla Lana School of Public Health, University of Toronto, Toronto, ON, R. Wong, Health Care and Outcomes Research, Toronto Western Research Institute, Toronto, ON, E. Schemitsch, Division of Orthopaedics, University of Toronto and St. Michael's, Toronto, ON, N. N. Mahomed, Division of Orthopaedics, University of Toronto and The Arthritis Program, Toronto Western Hospital, Toronto, ON, J. Flannery, Department of Physiatry, University of Toronto and Toronto Rehabilitation Institute, Toronto, ON and E. M. Badley, Health Care and Outcomes Research, Toronto Western Research Institute; Dalla Lana School of Public Health, University of Toronto, Toronto, ON
Health Care and Outcomes Research, Toronto Western Research Institute; Departments of Physical Therapy and Rehabilitation Science, University of Toronto
Organization of Care Delivery for People with Arthritis: Models and Processes
A. M. Davis, Health Care and Outcomes Research, Toronto Western Research Institute; Departments of Rehabilitation Science and Health Policy, Management and Evaluation, University of Toronto, Toronto, ON, C. Cott, Health Care and Outcomes Research, Toronto Western Research Institute; Departments of Physical Therapy and Rehabilitation Science, University of Toronto, Toronto, ON, L. Li, Arthritis Centre of Canada and Department of Physical Therapy, University of British Columbia, Vancouver, BC, M. Landry, Departments of Physical Therapy and Rehabilitation Science, University of Toronto, Toronto, ON, A. Jones, Departments of Physical Therapy and School of Public Health, University of Alberta, Edmonton, AB, R. Wong, Health Care and Outcomes Research, Toronto Western Research Institute, Toronto, ON, C. Frank, Alberta Bone and Joint Institute and Department of Surgery, University of Calgary, Calgary, AB, L. Bergeron, Canadian Arthritis Patient Alliance, Ottawa, ON, R. Birtwhistle, Centre for Studies in Primary Care and Family Medicine and Community Health and Epidemiology, Queen's University, Kingston, ON and E. M. Badley, Health Care and Outcomes Research, Toronto Western Research Institute; Dalla Lana School of Public Health, University of Toronto, Toronto, ON
Health Care and Outcomes Research, Toronto Western Research Institute; Departments of Rehabilitation Science and Health Policy, Management and Evaluation, University of Toronto
Predictors of Suboptimal Patient Outcome Following Total Joint Arthroplasty
Gillian A. Hawker1, Ruth Croxford2, A. M. Davis3, Sheila Dunn1, Joy G. Elkayam1, Melissa R. French1, M. A. Gignac4, Susan B. Jaglal5 and Joanna Sale5, 1Women's College Hospital, Toronto, ON, 2Institute for Clinical and Evaluative Science, Toronto, ON, 3Health Care and Outcomes Research, Toronto Western Research Institute; Departments of Rehabilitation Science and Health Policy, Management and Evaluation, University of Toronto, Toronto, ON, 4Health Care and Outcomes Research, Toronto Western Research Institute; Dalla Lana School of Public Health, University of Toronto, Toronto, ON, 5University of Toronto, Toronto, ON

Organization of Care Delivery for People with Arthritis: Models and Processes
A. M. Davis, Health Care and Outcomes Research, Toronto Western Research Institute; Departments of Rehabilitation Science and Health Policy, Management and Evaluation, University of Toronto, Toronto, ON, C. Cott, Health Care and Outcomes Research, Toronto Western Research Institute; Departments of Physical Therapy and Rehabilitation Science, University of Toronto, Toronto, ON, L. Li, Arthritis Centre of Canada and Department of Physical Therapy, University of British Columbia, Vancouver, BC, M. Landry, Departments of Physical Therapy and Rehabilitation Science, University of Toronto, Toronto, ON, A. Jones, Departments of Physical Therapy and School of Public Health, University of Alberta, Edmonton, AB, R. Wong, Health Care and Outcomes Research, Toronto Western Research Institute, Toronto, ON, C. Frank, Alberta Bone and Joint Institute and Department of Surgery, University of Calgary, Calgary, AB, L. Bergeron, Canadian Arthritis Patient Alliance, Ottawa, ON, R. Birtwhistle, Centre for Studies in Primary Care and Family Medicine and Community Health and Epidemiology, Queen's University, Kingston, ON and E. M. Badley, Health Care and Outcomes Research, Toronto Western Research Institute; Dalla Lana School of Public Health, University of Toronto, Toronto, ON

Tool for Patient Selection to Optimize Patient-Reported Outcomes Following Total Joint Arthroplasty
Gillian A. Hawker1, Ruth Croxford2, A. M. Davis3, Sheila Dunn1, Joy G. Elkayam1, Melissa R. French1, M. A. Gignac4, Susan B. Jaglal5 and Joanna Sale5, 1Women's College Hospital, Toronto, ON, 2Institute for Clinical and Evaluative Science, Toronto, 3Health Care and Outcomes Research, Toronto Western Research Institute; Departments of Rehabilitation Science and Health Policy, Management and Evaluation, University of Toronto, Toronto, ON, 4Health Care and Outcomes Research, Toronto Western Research Institute; Dalla Lana School of Public Health, University of Toronto, Toronto, ON, 5University of Toronto, Toronto, ON

Improvement 3 to 12 Months Post Hip and Knee Replacement: Implications for Rehabilitation
A. M. Davis, Health Care and Outcomes Research, Toronto Western Research Institute; Departments of Rehabilitation Science and Health Policy, Management and Evaluation, University of Toronto, Toronto, ON, A. V. Perruccio, Department of Orthopedic Surgery and The Arthritis Program, Toronto Western Hospital, Toronto, ON, S. Ibrahim, Institute for Work and Health, Toronto, ON, S. Hogg-Johnson, Institute for Work and Health, and Dalla Lana School of Public Health, University of Toronto, Toronto, ON, R. Wong, Health Care and Outcomes Research, Toronto Western Research Institute, Toronto, ON, E. Schemitsch, Division of Orthopaedics, University of Toronto and St. Michael's, Toronto, ON, N. N. Mahomed, Division of Orthopaedics, University of Toronto and The Arthritis Program, Toronto Western Hospital, Toronto, ON, J. Flannery, Department of Physiatry, University of Toronto and Toronto Rehabilitation Institute, Toronto, ON and E. M. Badley, Health Care and Outcomes Research, Toronto Western Research Institute; Dalla Lana School of Public Health, University of Toronto, Toronto, ON
Health Center "Ciudad Jardín"
Application of Combined Algorithms with Peripheral Bone Mineral Density (BMD) and Risk Indeces to Reduce the Requirement for Central Dual X-Ray Absorptometry (DXA)
María América López-Lasanta1, Francisco G. Jiménez-Núñez1, Carmen M. Romero-Barco1, Sara Manrique-Arija1, Verónica Rodriguez-García1, Miguel A. Descalzo2, Blanca Panero1, Jose Mancera Romero3, Silvia Mesa González3, Maria Carmen Ordóñez1, Inmaculada Ureña1, Manuel Rodríguez-Pérez1 and Antonio Fernandez-Nebro4, 1Hospital Regional Universitario Carlos Haya., Málaga, Spain, 2Spanish Society of Rheumatology, Madrid, Spain, 3Health Center "Ciudad Jardín", Malaga, Spain, 4Hospital Regional Universitario Carlos Haya, Málaga, Spain
Health Research of Hampton Roads
Safety, Tolerability, and Immunogenicity of Zoster Vaccine in Patients on Chronic/Maintenance Corticosteroids
Janie Parrino1, Farid Marquez2, Chester L. Fisher Jr.3, Wolfgang Spieler4, Tadeusz Tomala5, Jon E. Stek1, Amy F. Russell1, Kathleen E. Coll1, Shu-Chih Su1, Jin Xu1, Xiaoming Li1, Katia Schlienger1 and Jaffrey L. Silber1, 1Merck Sharp & Dohme Corp., Whitehouse Station, NJ, 2Palm Springs Research Institute, Hialeah, FL, 3Health Research of Hampton Roads, Newport News, VA, 4Rheumatology Specialty Practice, Zerbst, Germany, 5Svelvik Medical, Svelvik, Norway
Health Research of Oklahoma
One Year Efficacy and Safety Results of a Phase II Trial of Secukinumab in Patients with Rheumatoid Arthritis
Mark C. Genovese1, Patrick Durez2, Hanno B. Richards3, Jerzy Supronik4, Eva Dokoupilova5, Jacob A. Aelion6, Sang-Heon Lee7, Christine E. Codding8, Herbert Kellner9, Takashi Ikawa10, Sophie Hugot3, Gregory Ligozio11 and Shephard Mpofu3, 1Stanford University, Palo Alto, CA, 2Cliniques Universitaires Saint-Luc, Université Catholique de Louvain, Brussels, Belgium, 3Novartis Pharma AG, Basel, Switzerland, 4NZOZ Centrum Medyczne Artur Racewicz, Bialystok, Poland, 5Medical Plus s.r.o, Uherske Hradiste, Czech Republic, 6Arthritis Clinic, Jackson, TN, 7Konkuk University Medical Center, Seoul, South Korea, 8Health Research of Oklahoma, Oklahoma City, OK, 9Centre for Inflammatory Joint Diseases, Munich, Germany, 10Kobe - Konan Yamate Clinic, Kobe, Japan, 11Novartis Pharmaceuticals Corporation, East Hanover, NJ

A Phase I, Randomized, Double-Blind, Placebo-Controlled, Single-Dose, Dose Escalation Study to Evaluate the Safety, Tolerability and Pharmacokinetics of BIIB023 (Anti-TWEAK) in Subjects with Rheumatoid Arthritis
Nicolas Wisniacki1, Vishala L. Chindalore2, Christine E. Codding3, Maria W. Greenwald4, Marianne L. Shaw5, Sergey Fitilev6, Olga Ershova7, Xiao Hu8, Timothy S. Zheng9, Lakshmi Amaravadi8, Ray Zhang9 and Linda C. Burkly8, 1Biogen Idec, Maidenhead, United Kingdom, 2Anniston Medical Clinic PC, Anniston, AL, 3Health Research of Oklahoma, Oklahoma City, OK, 4Desert Medical Advances, Palm Desert, CA, 5Duncansville, PA, 6M. Sechenov Moscow Medical Academy, Moscow, Russia, 7Clinical Hospital for Emergency Care, Moscow, Russia, 8Biogen Idec, Cambridge, MA, 9Biogen Idec Inc, Cambridge, MA
Health Sciences Centre
Polymorphisms in the CCL2 Distal Regulatory Region Are Associated with Rheumatoid Arthritis in a North American Native Population with a High Disease Prevalence
Hani S. El-Gabalawy1, Konstantin Jilkine1, David B. Robinson1, Irene Smolik2, Donna M. Hart3, Carol A. Hitchon1, Christine A. Peschken1, Charles N. Bernstein1, Kiem Oen1, Ye Sun4 and Katherine A. Siminovitch4, 1University of Manitoba, Winnipeg, MB, 2University of Manitoba, Winnipeg, 3Health Sciences Centre, Winnipeg, MB, 4Mount Sinai Hospital, Toronto, ON

Familial Clustering of the Serum Cytokine Profile: Comparison Between the Asymptomatic First-Degree Relatives of RA Patients and Controls with No Family History of Autoimmune Disease
Hani S. El-Gabalawy1, David B. Robinson1, Donna M. Hart2, Irene Smolik3, Charles N. Bernstein1, Marianna M. Newkirk4 and Marvin J. Fritzler5, 1University of Manitoba, Winnipeg, MB, 2Health Sciences Centre, Winnipeg, MB, 3University of Manitoba, Winnipeg, 4McGill University Health Centr, Montreal, QC, 5University of Calgary, Calgary, AB

Prevalence of Periodontitis, Anti-P. Gingivalis antibodies, and RA Autoantibodies in a Community Sample of North American Natives with Prevalent RA
Isanne Schacter1, David B. Robinson1, Donna M. Hart2, Mary Bertone1, Christine A. Peschken1, Irene Smolik3, Carol A. Hitchon1 and Hani S. El-Gabalawy1, 1University of Manitoba, Winnipeg, MB, 2Health Sciences Centre, Winnipeg, MB, 3University of Manitoba, Winnipeg

Pregnancy and the Risk of Rheumatoid Arthritis In a High Risk North American Native Population
Christine A. Peschken1, David B. Robinson1, Irene Smolik1, Carol A. Hitchon1, Donna M. Hart2, Charles N. Bernstein1 and Hani El-Gabalawy1, 1University of Manitoba, Winnipeg, MB, 2Health Sciences Centre, Winnipeg, MB
Health Services Research, University of California San Diego
Gout Characteristics, Health-Related Quality of Life and Health Care Utilization: Caucasians Vs. Non-Caucasians In An Observational Cohort of Patients with Gout
Puja Khanna1, Jan Hirsch2, Susan J. Lee3, Robert Terkeltaub4, Jasvinder Singh5, Arthur F. Kavanaugh6, Andrew Sarkin7 and Dinesh Khanna1, 1University of Michigan, Ann Arbor, MI, 2Skaggs School of Pharmacy & Pharmaceutical Sciences, University of California San Diego, San Diego, CA, 3Univ of California San Diego, La Jolla, CA, 4VA Medical Ctr, San Diego, CA, 5University of Alabama and VA Medical Center, Birmingham, AL, 6University of California San Diego, San Diego, CA, 7Health Services Research, University of California San Diego, San Diego, CA
Healthcare Information and Management Systems Society
The Innovation Agenda and Health Information Technology
Rod Piechowski, Healthcare Information and Management Systems Society, Chicago, IL
Heartland Clinic
Patient Reported Outcomes In a Single Community Based Rheumatology Practice, - Outcomes Not As Good As We Think?
Melinda K. Pemberton, Heartland Clinic, St Joseph, MO, Gary Runde, Heartland Regional Medical Center, Saint Joseph, MO and Wendell D. Bronson, Heartland Clinic, St. Joseph, MO
Heartland Regional Medical Center
Patient Reported Outcomes In a Single Community Based Rheumatology Practice, - Outcomes Not As Good As We Think?
Melinda K. Pemberton, Heartland Clinic, St Joseph, MO, Gary Runde, Heartland Regional Medical Center, Saint Joseph, MO and Wendell D. Bronson, Heartland Clinic, St. Joseph, MO
Hebrew Senior Life
Does Hallux Valgus and Foot Pain Affect Self-Reported Lower Extremity Limitations in Men and Women? the Framingham Study
Alyssa B. Dufour1, Virginia A. Casey2, Patricia P. Katz3, Robert R. McLean4 and Marian T. Hannan4, 1Hebrew SeniorLife & Boston Univ, Boston, MA, 2Hebrew Senior Life, Boston, MA, 3Univercity of California San Francisco, San Francisco, CA, 4Hebrew SeniorLife & Harvard Med Sch, Boston, MA

Foot Type Is Linked to Falls in Older Adults: The Framingham Foot Study
Jody L. Riskowski1, Thomas J. Hagedorn2, Alyssa B. Dufour3, Virginia A. Casey2 and Marian T. Hannan4, 1Hebrew SeniorLife, Boston, MA, 2Hebrew Senior Life, Boston, MA, 3Hebrew SeniorLife & Boston Univ, Boston, MA, 4Hebrew SeniorLife & Harvard Med Sch, Boston, MA

The Effect of Foot Pain on Mobility Disability in Older Adults: The Framingham Foot Study
Virginia A. Casey1, Alyssa B. Dufour2, Jody L. Riskowski3, Thomas J. Hagedorn1, Robert R. McLean4 and Marian T. Hannan5, 1Hebrew Senior Life, Boston, MA, 2Hebrew SeniorLife & Boston Univ, Boston, MA, 3Hebrew SeniorLife, Boston, MA, 4Hebrew Senior Life/Harvard Medical School, Boston, MA, 5Hebrew SeniorLife & Harvard Med Sch, Boston, MA

Lesser Toe Deformities Are Highly Heritable in Older Men and Women: The Framingham Foot Study
Marian T. Hannan1, Yi-Hsiang Hsu1, Virginia A. Casey2, Gouri Vadali2 and Joanne M. Jordan3, 1Hebrew SeniorLife & Harvard Med Sch, Boston, MA, 2Hebrew Senior Life, Boston, MA, 3UNC Thurston Arthritis Center, Chapel Hill, NC

Factors Affecting Dynamic Foot Function in Older Adults: The Framingham Foot Study
Thomas J. Hagedorn1, Alyssa B. Dufour2, Yvonne M. Golightly3, Jody L. Riskowski4, Howard J. Hillstrom5, Virginia A. Casey1 and Marian T. Hannan6, 1Hebrew Senior Life, Boston, MA, 2Hebrew SeniorLife & Boston Univ, Boston, MA, 3University of North Carolina, Chapel Hill, NC, 4Hebrew SeniorLife, Boston, MA, 5Hospital Special Surgery (HSS), New York, NY, 6Hebrew SeniorLife & Harvard Med Sch, Boston, MA
Hebrew Senior Life/Harvard Medical School
Does Physical Performance Mediate the Effect of Knee Osteoarthritis and Risk of Indoor and Outdoor Falls in Older Men and Women?
Uyen Sa D. Nguyen1, Yuqing Zhang1, Tyler J. VanderWeele2, Jingbo Niu1, Robert H. Shmerling3, Douglas P. Kiel4, Suzanne G. Leveille5, Carol A. Oatis6 and Marian T. Hannan7, 1Boston University School of Medicine, Boston, MA, 2Harvard School of Public Health, Boston, MA, 3Beth Israel Deaconess Med Ctr, Boston, MA, 4Hebrew Senior Life/Harvard Medical School, Boston, MA, 5University of Massachusetts-Boston, Boston, MA, 6Arcadia University, Glenside, PA, 7Hebrew SeniorLife & Harvard Med Sch, Boston, MA

The Effect of Foot Pain on Mobility Disability in Older Adults: The Framingham Foot Study
Virginia A. Casey1, Alyssa B. Dufour2, Jody L. Riskowski3, Thomas J. Hagedorn1, Robert R. McLean4 and Marian T. Hannan5, 1Hebrew Senior Life, Boston, MA, 2Hebrew SeniorLife & Boston Univ, Boston, MA, 3Hebrew SeniorLife, Boston, MA, 4Hebrew Senior Life/Harvard Medical School, Boston, MA, 5Hebrew SeniorLife & Harvard Med Sch, Boston, MA

How Does Loss to Follow up Happen and What Are the Implications?
Robert R. McLean, Hebrew Senior Life/Harvard Medical School, Boston, MA

Highlights from the 2011 ARHP Sessions
Robert R. McLean, Hebrew Senior Life/Harvard Medical School, Boston, MA
Hebrew SeniorLife
Foot Type Is Linked to Falls in Older Adults: The Framingham Foot Study
Jody L. Riskowski1, Thomas J. Hagedorn2, Alyssa B. Dufour3, Virginia A. Casey2 and Marian T. Hannan4, 1Hebrew SeniorLife, Boston, MA, 2Hebrew Senior Life, Boston, MA, 3Hebrew SeniorLife & Boston Univ, Boston, MA, 4Hebrew SeniorLife & Harvard Med Sch, Boston, MA

The Effect of Foot Pain on Mobility Disability in Older Adults: The Framingham Foot Study
Virginia A. Casey1, Alyssa B. Dufour2, Jody L. Riskowski3, Thomas J. Hagedorn1, Robert R. McLean4 and Marian T. Hannan5, 1Hebrew Senior Life, Boston, MA, 2Hebrew SeniorLife & Boston Univ, Boston, MA, 3Hebrew SeniorLife, Boston, MA, 4Hebrew Senior Life/Harvard Medical School, Boston, MA, 5Hebrew SeniorLife & Harvard Med Sch, Boston, MA

Factors Affecting Dynamic Foot Function in Older Adults: The Framingham Foot Study
Thomas J. Hagedorn1, Alyssa B. Dufour2, Yvonne M. Golightly3, Jody L. Riskowski4, Howard J. Hillstrom5, Virginia A. Casey1 and Marian T. Hannan6, 1Hebrew Senior Life, Boston, MA, 2Hebrew SeniorLife & Boston Univ, Boston, MA, 3University of North Carolina, Chapel Hill, NC, 4Hebrew SeniorLife, Boston, MA, 5Hospital Special Surgery (HSS), New York, NY, 6Hebrew SeniorLife & Harvard Med Sch, Boston, MA

Severe Foot Pain, but Not Milder Foot Pain, Is Linked to Falls in Older Men and Women: The Framingham Study
Alyssa B. Dufour1, Virginia A. Casey2, Thomas J. Hagedorn2, Jody L. Riskowski2 and Marian T. Hannan3, 1Hebrew SeniorLife & Boston Univ, Boston, MA, 2Hebrew SeniorLife, Boston, MA, 3Hebrew SeniorLife & Harvard Med Sch, Boston, MA
Hebrew SeniorLife & Boston Univ
Does Hallux Valgus and Foot Pain Affect Self-Reported Lower Extremity Limitations in Men and Women? the Framingham Study
Alyssa B. Dufour1, Virginia A. Casey2, Patricia P. Katz3, Robert R. McLean4 and Marian T. Hannan4, 1Hebrew SeniorLife & Boston Univ, Boston, MA, 2Hebrew Senior Life, Boston, MA, 3Univercity of California San Francisco, San Francisco, CA, 4Hebrew SeniorLife & Harvard Med Sch, Boston, MA

Factors Associated with Hallux Valgus: The Johnston County Osteoarthritis Project
Yvonne M. Golightly1, Marian T. Hannan2, Alyssa B. Dufour3, Jordan Renner4 and Joanne M. Jordan1, 1UNC Thurston Arthritis Research Center, Chapel Hill, NC, 2Hebrew SeniorLife & Harvard Med Sch, Boston, MA, 3Hebrew SeniorLife & Boston Univ, Boston, MA, 4University of North Carolina at Chapel Hill, Chapel Hill, NC

Foot Type Is Linked to Falls in Older Adults: The Framingham Foot Study
Jody L. Riskowski1, Thomas J. Hagedorn2, Alyssa B. Dufour3, Virginia A. Casey2 and Marian T. Hannan4, 1Hebrew SeniorLife, Boston, MA, 2Hebrew Senior Life, Boston, MA, 3Hebrew SeniorLife & Boston Univ, Boston, MA, 4Hebrew SeniorLife & Harvard Med Sch, Boston, MA

The Effect of Foot Pain on Mobility Disability in Older Adults: The Framingham Foot Study
Virginia A. Casey1, Alyssa B. Dufour2, Jody L. Riskowski3, Thomas J. Hagedorn1, Robert R. McLean4 and Marian T. Hannan5, 1Hebrew Senior Life, Boston, MA, 2Hebrew SeniorLife & Boston Univ, Boston, MA, 3Hebrew SeniorLife, Boston, MA, 4Hebrew Senior Life/Harvard Medical School, Boston, MA, 5Hebrew SeniorLife & Harvard Med Sch, Boston, MA

Factors Affecting Dynamic Foot Function in Older Adults: The Framingham Foot Study
Thomas J. Hagedorn1, Alyssa B. Dufour2, Yvonne M. Golightly3, Jody L. Riskowski4, Howard J. Hillstrom5, Virginia A. Casey1 and Marian T. Hannan6, 1Hebrew Senior Life, Boston, MA, 2Hebrew SeniorLife & Boston Univ, Boston, MA, 3University of North Carolina, Chapel Hill, NC, 4Hebrew SeniorLife, Boston, MA, 5Hospital Special Surgery (HSS), New York, NY, 6Hebrew SeniorLife & Harvard Med Sch, Boston, MA

Severe Foot Pain, but Not Milder Foot Pain, Is Linked to Falls in Older Men and Women: The Framingham Study
Alyssa B. Dufour1, Virginia A. Casey2, Thomas J. Hagedorn2, Jody L. Riskowski2 and Marian T. Hannan3, 1Hebrew SeniorLife & Boston Univ, Boston, MA, 2Hebrew SeniorLife, Boston, MA, 3Hebrew SeniorLife & Harvard Med Sch, Boston, MA

How to Avoid or Deal with Loss to Follow Up
Alyssa B. Dufour, Hebrew SeniorLife & Boston Univ, Boston, MA
Hebrew SeniorLife & Harvard Med Sch
Does Physical Performance Mediate the Effect of Knee Osteoarthritis and Risk of Indoor and Outdoor Falls in Older Men and Women?
Uyen Sa D. Nguyen1, Yuqing Zhang1, Tyler J. VanderWeele2, Jingbo Niu1, Robert H. Shmerling3, Douglas P. Kiel4, Suzanne G. Leveille5, Carol A. Oatis6 and Marian T. Hannan7, 1Boston University School of Medicine, Boston, MA, 2Harvard School of Public Health, Boston, MA, 3Beth Israel Deaconess Med Ctr, Boston, MA, 4Hebrew Senior Life/Harvard Medical School, Boston, MA, 5University of Massachusetts-Boston, Boston, MA, 6Arcadia University, Glenside, PA, 7Hebrew SeniorLife & Harvard Med Sch, Boston, MA

Does Hallux Valgus and Foot Pain Affect Self-Reported Lower Extremity Limitations in Men and Women? the Framingham Study
Alyssa B. Dufour1, Virginia A. Casey2, Patricia P. Katz3, Robert R. McLean4 and Marian T. Hannan4, 1Hebrew SeniorLife & Boston Univ, Boston, MA, 2Hebrew Senior Life, Boston, MA, 3Univercity of California San Francisco, San Francisco, CA, 4Hebrew SeniorLife & Harvard Med Sch, Boston, MA

Factors Associated with Hallux Valgus: The Johnston County Osteoarthritis Project
Yvonne M. Golightly1, Marian T. Hannan2, Alyssa B. Dufour3, Jordan Renner4 and Joanne M. Jordan1, 1UNC Thurston Arthritis Research Center, Chapel Hill, NC, 2Hebrew SeniorLife & Harvard Med Sch, Boston, MA, 3Hebrew SeniorLife & Boston Univ, Boston, MA, 4University of North Carolina at Chapel Hill, Chapel Hill, NC

Foot Type Is Linked to Falls in Older Adults: The Framingham Foot Study
Jody L. Riskowski1, Thomas J. Hagedorn2, Alyssa B. Dufour3, Virginia A. Casey2 and Marian T. Hannan4, 1Hebrew SeniorLife, Boston, MA, 2Hebrew Senior Life, Boston, MA, 3Hebrew SeniorLife & Boston Univ, Boston, MA, 4Hebrew SeniorLife & Harvard Med Sch, Boston, MA

The Effect of Foot Pain on Mobility Disability in Older Adults: The Framingham Foot Study
Virginia A. Casey1, Alyssa B. Dufour2, Jody L. Riskowski3, Thomas J. Hagedorn1, Robert R. McLean4 and Marian T. Hannan5, 1Hebrew Senior Life, Boston, MA, 2Hebrew SeniorLife & Boston Univ, Boston, MA, 3Hebrew SeniorLife, Boston, MA, 4Hebrew Senior Life/Harvard Medical School, Boston, MA, 5Hebrew SeniorLife & Harvard Med Sch, Boston, MA

Lesser Toe Deformities Are Highly Heritable in Older Men and Women: The Framingham Foot Study
Marian T. Hannan1, Yi-Hsiang Hsu1, Virginia A. Casey2, Gouri Vadali2 and Joanne M. Jordan3, 1Hebrew SeniorLife & Harvard Med Sch, Boston, MA, 2Hebrew Senior Life, Boston, MA, 3UNC Thurston Arthritis Center, Chapel Hill, NC

Factors Affecting Dynamic Foot Function in Older Adults: The Framingham Foot Study
Thomas J. Hagedorn1, Alyssa B. Dufour2, Yvonne M. Golightly3, Jody L. Riskowski4, Howard J. Hillstrom5, Virginia A. Casey1 and Marian T. Hannan6, 1Hebrew Senior Life, Boston, MA, 2Hebrew SeniorLife & Boston Univ, Boston, MA, 3University of North Carolina, Chapel Hill, NC, 4Hebrew SeniorLife, Boston, MA, 5Hospital Special Surgery (HSS), New York, NY, 6Hebrew SeniorLife & Harvard Med Sch, Boston, MA

Severe Foot Pain, but Not Milder Foot Pain, Is Linked to Falls in Older Men and Women: The Framingham Study
Alyssa B. Dufour1, Virginia A. Casey2, Thomas J. Hagedorn2, Jody L. Riskowski2 and Marian T. Hannan3, 1Hebrew SeniorLife & Boston Univ, Boston, MA, 2Hebrew SeniorLife, Boston, MA, 3Hebrew SeniorLife & Harvard Med Sch, Boston, MA

Publishing in Arthritis Care & Research
Marian T. Hannan, Hebrew SeniorLife & Harvard Med Sch, Boston, MA

Footwear and Foot Pain: Evidence from Population-Based Studies
Marian T. Hannan, Hebrew SeniorLife & Harvard Med Sch, Boston, MA
Hebrew University- Hadassah Ein Kerem
Sirt1 Deficient Mice Exhibit An Altered Cartilage Phenotype
Odile H. Gabay Engel1, Christelle Sanchez2, Mona dvir-Ginzberg3, Viktoria Gagarina1, Eun Jin Lee1, Kristien J. Zaal1, Michael McBurney4 and David J. Hall1, 1NIH, Bethesda, MD, 2Bone and Cartilage Research Unit, Liege, Belgium, 3Hebrew University- Hadassah Ein Kerem, Jerusalem, Israel, 4Ottawa Hospital, Ottawa, ON
Hefner Eye Care and Optical Center
Gene Expression Profiling in a Cohort of 275 European American Sjögren's Syndrome Patients and Controls
Jennifer A. Kelly1, Christopher J. Lessard1, Indra Adrianto1, John A. Ice1, He Li1, Stuart B. Glenn1, Kimberly Hefner2, Evan Glenn Vista3, Donald U. Stone4, Raj Gopalakrishnan5, Glen D. Houston4, David M. Lewis4, Michael Rohrer5, Pamela Hughes5, John B. Harley6, Courtney G. Montgomery1, James Chodosh7, James A. Lessard8, Juan-Manuel Anaya9, Barbara M. Segal10, Nelson L. Rhodus5, Lida Radfar4, M. Bart Frank1, Robert H. Scofield11 and Kathy L. Moser1, 1Oklahoma Medical Research Foundation, Oklahoma City, OK, 2Hefner Eye Care and Optical Center, Oklahoma City, OK, 3University of Santo Tomas, Taguig City, Philippines, 4University of Oklahoma Health Sciences Center, Oklahoma City, OK, 5University of Minnesota, Minneapolis, MN, 6Cincinnati Children's Hospital Medical Center and the US Department of Veterans Affairs Medical Center, Cincinnati, OH, 7Harvard Clinical and Translational Science Center, Boston, MA, 8Valley Bone & Joint Clinic, Grand Forks, ND, 9Universidad del Rosario-Corporacion para Investigaciones Biologicas, Bogota, Colombia, 10Univ of Minnesota, Minneapolis, MN, 11Arthritis and Clinical Immunology Research Program, Oklahoma Medical Research Foundation, US Department of Veterans Affairs Medical Center and Department of Medicine, University of Oklahoma Health Sciences Center, Oklahoma City, OK
Heinrich-Heine-University
Effort-Reward Imbalance in Patients with Rheumatoid Arthritis?
Jutta G. Richter, Thomas Muth, Birthe Koerbl, Nicole Hoffmann, Tobias Koch, Johannes Siegrist and Matthias Schneider, Heinrich-Heine-University, Duesseldorf, Germany

Current Smoking and Hypertension Are Associated with Synovitis As Measured by Ultrasonography in Therapy-Naive Patients with Recent Onset Arthritis: Results from an Early Arthritis Cohort
Gisela Westhoff, German Rheumatism Research Center Berlin, Berlin, Germany, Georg Schett, Department of Internal Medicine 3 and Institute for Clinical Immunology, University of Erlangen-Nuremberg, Erlangen, Germany, Edmund Edelmann, Rheumatologische Gemeinschaftspraxis, Berufsverband Deutscher Rheumatologen e.V, Bad Aibling, Germany, Matthias Schneider, Heinrich-Heine-University, Duesseldorf, Germany, Angela Zink, Deutsches Rheumaforschungszentrum and Charité University Medicine, Berlin, Germany and Marina Backhaus, Charite University Hospital, Berlin, Germany

Impact of Different Biologic Agents on the Improvement of Fatigue
Anja Strangfeld, Deutsches Rheumaforschungszentrum, Berlin, Germany, Matthias Schneider, Heinrich-Heine-University, Duesseldorf, Germany, Jörg Kaufmann, Rheumatologist, Ludwigsfelde, Germany, Andreas Krause, Immanuel Krankenhaus Berlin-Buch, Berlin, Germany, Angela Zink, Deutsches Rheumaforschungszentrum and Charité University Medicine, Berlin, Germany and Joachim Listing, German Rheumatism Research Centre, Berlin, Germany

Comparison of High-Resolution Multi-Pinhole SPECT and MRI for Monitoring Early Arthritis Patients Under Methotrexat Therapy: First Results
Christian Buchbender1, Philipp Sewerin1, Axel Scherer1, Falk Miese1, Oliver Sander1, Katalin Mattes-György1, Hans-Jörg Wittsack1, Christof Specker2, Gerald Antoch1, Matthias Schneider1 and Ben Ostendorf1, 1Heinrich-Heine-University, Düsseldorf, Germany, 2Kliniken Essen Süd, Essen, Germany

Effort-Reward Imbalance in Patients with Systemic Lupus Erythematodes?
Jutta G. Richter, Thomas Muth, Birthe Koerbl, Nicole Hoffmann, Tobias Koch, Johannes Siegrist and Matthias Schneider, Heinrich-Heine-University, Duesseldorf, Germany

Life and Job Satisfaction in Patients with Systemic Lupus Erythematosus
Jutta G. Richter, Thomas Muth, Birthe Koerbl, Mia Vidakovic, Tobias Koch and Matthias Schneider, Heinrich-Heine-University, Duesseldorf, Germany

The Substantial Negative Impact of Systemic Lupus Erythematosus on the Working Lives of Patients: Results of the Lupus European Online Survey
M. Schneider1, C. Gordon2, K. Lerstrøm3, M. Govoni4, E. Nikai4 and D.A. Isenberg5, 1Heinrich-Heine-University, Duesseldorf, Germany, 2University of Birmingham, Birmingham, United Kingdom, 3LUPUS EUROPE, Farum, Denmark, 4UCB, Brussels, Belgium, 5University College of London, London, United Kingdom
Heinrich-Heine-University Düsseldorf
Defensins and Cardiovascular Disease In Systemic Lupus Erythematosus
Stefan Vordenbäumen, Oliver Sander, Ellen Bleck, Matthias Schneider and Rebecca Fischer-Betz, Heinrich-Heine-University Düsseldorf, Düsseldorf, Germany
Helen Hayes Hospital
Bone Biology and RANK Ligand
David W. Dempster, Helen Hayes Hospital, West Haverstraw, NY
Helios Clinics
Double Blind, Placebo-Controlled Trial with Adalimumab for Treatment of Juvenile Ankylosing Spondylitis (jAS)
Gerd Horneff1, Sigrid Fitter1, Hans-Iko Huppertz2, Ivan Foeldvari3, Jasmin B. Kuemmerle-Deschner4, Rolf M. Kuester5, Nikolay Tzaribachev6, Angelika Thon7, Michael Borte8, Gerd Ganser9, Ralf Trauzeddel10 and Kirsten Minden11, 1Asklepios Clinic Sankt Augustin, Sankt Augustin, Germany, 2Krinikum Bremen-Mitte, Bremen, Germany, 3Hamburger Zentrum Kinder-und Jugendrheumatologie, Hamburg, Germany, 4University Hospital Tuebingen, Tuebingen, Germany, 5Rheumaklinik Bad Bramstedt, Bad Bramstedt, Germany, 6Center for Rheumatic Diseases, Bad Bramstedt, Germany, 7Kinderklinik der Medizinischen Hochschule Hannover, Hannover, Germany, 8Sankt Georg Clinics, Leeipzig, Germany, 9Sankt Josef Stift, Sendenhorst, Germany, 10Helios Clinics, Berlin, Germany, 11Charite, Berlin, Germany
Hellenic Foundation for Rheumatological Research
Relative Effectiveness of Rituximab and An Alternative TNF Inhibitor in Patients with Rheumatoid Arthritis and An Inadequate Response to a Single Previous TNF Inhibitor: Interim Results From Switch-RA a Global Comparative-Effectiveness Observational Study
Paul Emery1, Piercarlo Sarzi-Puttini2, Robert J. Moots3, Alexandros A. Andrianakos4, Thomas P. Sheeran5, Denis Choquette6, Axel Finckh7, Marie-Laetitia Desjuzeur8, Eric Gemmen9, Chiedzo Mpofu8 and Jacques-Eric Gottenberg10, 1Chapel Allerton Hospital, Leeds, United Kingdom, 2L Sacco University Hospital, Milano, Italy, 3University of Liverpool, Liverpool, United Kingdom, 4Hellenic Foundation for Rheumatological Research, Athens, Greece, 5Cannock Chase Hospital, Cannock, United Kingdom, 6University of Montreal, Notre-dame Hospital, Montreal, QC, 7University Hospital of Geneva, Geneva, Switzerland, 8F. Hoffman-La Roche Ltd, Basel, Switzerland, 9Quintiles Inc, Rockville, MD, 10CHU Strasbourg, Strasbourg, France
Helsingborgs Lasarett and Lund University
Predicted Versus Observed Radiographic Progression in a Randomized Trial
Ronald F. van Vollenhoven1, Heléne Hanses1, Kristina Forslind2, Pierre Geborek3, Ingemar F. Petersson3, Sofia Ernestam4 and Johan Bratt4, 1The Karolinska Institute, Stockholm, Sweden, 2Helsingborgs Lasarett and Lund University, Lund, Sweden, 3Lund University, Lund, Sweden, 4Karolinska University Hospital, Stockholm, Sweden

Patients with Early Rheumatoid Arthritis (RA) Who Respond Well to Methotrexate Monotherapy Have Less Metacarpal Bone Loss, Measured by Digital X-Ray Radiogrammetry (DXR), Than Those Who Need Add-on Therapy. Findings From a Randomized Trial
Hamed Rezaei1, Saedis Saevarsdottir1, Kristina Forslind2, Pierre Geborek3, Ingemar F. Petersson3, Sofia Ernestam4, Johan Bratt4 and Ronald F. van Vollenhoven1, 1The Karolinska Institute, Stockholm, Sweden, 2Helsingborgs Lasarett and Lund University, Lund, Sweden, 3Lund University, Lund, Sweden, 4Karolinska University Hospital, Stockholm, Sweden

Development of a Matrix Risk Model to Predict Rapid Radiographic Progression in Early Rheumatoid Arthritis. Results From a Randomized Trial Population
Saedis Saevarsdottir1, Kristina Forslind2, Kristina Albertsson1, Hamed Rezaei1, Arvid Engström1, Pierre Geborek3, Ingemar F. Petersson3, Sofia Ernestam4, Johan Bratt4 and Ronald F. van Vollenhoven1, 1The Karolinska Institute, Stockholm, Sweden, 2Helsingborgs Lasarett and Lund University, Lund, Sweden, 3Lund University, Lund, Sweden, 4Karolinska University Hospital, Stockholm, Sweden
Helsinki Univ Central Hospital
Rheumatoid Arthritis Bone Fragility Is Associated with Increased Dickkopf-1 Expression and Disturbances in the Bone Turnover Regulating genes  
Joana Caetano-Lopes1, Ana M. Rodrigues2, Ana Lopes3, Ana Catarina Vale4, Michael A. Pitts-Kiefer5, Bruno Vidal6, Inês P. Perpétuo1, Jacinto Monteiro7, Yrjo T. Konttinen8, Maria Fátima Vaz4, Ara Nazarian5, Helena Canhão9 and João E. Fonseca10, 1Rheumatology Research Unit, Faculdade de Medicina da Universidade de Lisboa, Lisbon, Portugal, 2Rheumatology Research Unit, Instituto de Medicina Molecular, Faculdade de Medicina da Universidade de Lisboa and Rheumatology Department, Centro Hospitalar de Lisboa Norte, EPE, Hospital de Santa Maria, Lisbon, Portugal, 3Rheumatology Research Unit, Instituto de Medicina Molecular, Faculdade de Medicina da Universidade de Lisboa, Lisbon, Portugal, 4Department of Mechanical Engineering, Instituto Superior Técnico, ICEMS, Lisbon, Portugal, 5Center for Advanced Orthopaedic Studies, Department of Orthopaedic Surgery, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA, 6Instituto de Medicina Molecular, Faculdade de Medicina da Universidade de Lisboa, Lisbon, Portugal., Lisbon, Portugal, 7Orthopaedics Department, Hospital de Santa Maria, Lisbon, Portugal, 8Helsinki Univ Central Hospital, Helsinki, Finland, 9Instituto de Medicina Molecular, Faculdade de Medicina da Universidade de Lisboa and Rheumatology Department, Centro Hospitalar de Lisboa Norte, EPE, Hospital de Santa Maria, Lisboa, Portugal, 10Lisbon Academic Medical Center, on behalf of Rheumatic Diseases Portuguese Register (Reuma.pt), Lisbon, Portugal
Helsinki University Central Hospital
STAT3 Phosphorylation of Circulating Leukocytes Correlates with Disease Activity in Early Untreated Rheumatoid Arthritis
Krista Kuuliala1, Antti Kuuliala1, Saara Aittomäki1, Suvi Oksanen1, Sanna Siitonen2, Hannu Kautiainen3, Marjatta Leirisalo-Repo2 and Heikki Repo1, 1Haartman Institute, Helsinki, Finland, 2Helsinki University Central Hospital, Helsinki, Finland, 3Central Finland Central Hospital, Jyväskylä, Finland
Hematology and Clinical Immunology Unit
Treatment of Idiopathic Retroperitoneal Fibrosis: A Single Center Experience
Pietro Tartaro and Renzo Marcolongo, Hematology and Clinical Immunology Unit, Padova, Italy
Hematology Unit
Cell Clonality in Churg-Strauss Syndrome: What Pathogenetic Role?
Chiara Baldini1, Sara Galimberti2, Pasquale Pepe1, Sara Grossi1, Elisabetta Sordi2, Valeria Giorgerini1, Alessandra Della Rossa1 and Stefano Bombardieri1, 1Rheumatology Unit, Pisa, Italy, 2Hematology Unit, Pisa, Italy
Hematology, S.Gerardo Hospital
Lymphoma Prevalence in Patients with Serum Cryoglobulins with or without Cryoglobulinemic Vasculitis: Data Extrapolated From the Cryoglobulinemic Vasculitis Classification Criteria Database
Luca Quartuccio1, Laura Corazza2, Giuseppe Monti3, Armando Gabrielli4, Athanasios G. Tzioufas5, Clodoveo Ferri6, Gianfranco Ferraccioli7, Manuel Ramos-Casals8, Michael Voulgarelis9, Marco Lenzi10, Maria Teresa Mascia11, Domenico Sansonno12, Patrice Cacoub13, Matija Tomsic14, Antonio Tavoni15, Maurizio Pietrogrande16, Anna Linda Zignego17, Salvatore Scarpato18, Pietro Pioltelli19, Serge D. Steinfeld20, Peter Lamprecht21, Stefano Bombardieri22, Massimo Galli23 and Salvatore De Vita2, 1Rheumatology Clinic, DSMB, University of Udine, Italy, Udine, Italy, 2Rheumatology Clinic, DSMB, University of Udine, Udine, Italy, 3Internal Medicine Unit, Saronno Hospital, Azienda Ospedaliera di Busto Arsizio, Saronno (VA), Italy, 4Clinica Universitaria Ancona, Ancona, Italy, 5Medical School-Univ of Athens, Athens, Greece, 6Rheumatology Unit, University of Modena and Reggio Emilia, Modena, Italy, 7Division of Rheumatology, Catholic University of the Sacred Heart, Rome, Italy, 8IDIBAPS, Hospital Clínic, Barcelona, Spain, 9Department of Pathophysiology, Athens, Greece, 10Department of Clinical Medicine, University of Bologna, S. Orsola-Malpighi Hospital, Bologna, Italy, 11Dipartimento Apparato Locomotore, AOU Policlinico di Modena, Modena, Italy, 12Section of Internal Medicine and Clinical Oncology, Department of Biomedical Sciences and Human Oncology, University of Bari, Medical School, Bari, Italy, 13CHU Pitié-Salpêtrière, Paris, France, 14University Medical Centre Ljubjana, Ljubljana, Slovenia, 15Via Roma 67, Pisa, Italy, 16Internal Medicine Unit, Policlinico San Marco, Bergamo, Italy, 17viale Morgagni 85, Florence, Italy, 18Rheumatology Unit, M. Scarlato Hospital, Scafati, Salerno, Italy, 19Hematology, S.Gerardo Hospital, Monza, Italy, 20Clinique Saint-Jean, Brussels, Belgium, 21Oskar-Alexander-Street 26, Bad Bramstedt, Germany, 22Rheumatology Unit, Pisa, Italy, 23Istituto di Malattie Infettive e Tropicali, Università di Milano c/o Ospedale L. Sacco, Milano, Italy
Hemostase Poitiers
European Registry of Babies Born to Mothers with Antiphospholipid Syndrome
Arsene Mekinian1, Priscille loire-Berson2, Eric Lachassinne3, Pascale nicaise-Roland4, Eric Vicaut5, Jerome Stirnemann6, Sylvie chollet-Martin4, Mario Motta7, Angela Tincani8, Christine Boinot9, Olivier Pourrat10, Tadej Avcin11, Rapr Tomsik12, Amelie Benbara2, Sarah de Carolis13, Patricia Rovere14, Lionel Carbillon2, marie-Helene Aurousseau15, marie-Claire Boffa16 and Olivier Fain6, 1Jean Verdier Hospital, Bondy, France, 2Service de gynécologie-obstétrique, Université Paris 13, AP-HP, Hôpital Jean Verdier, 93140, Bondy, France., Bondy, France, 3Service de néonatologie et pédiatrie, Université Paris 13, AP-HP, Hôpital Jean Verdier, 93140, Bondy, France., Bondy, France, 4Unité Fonctionnelles d'Immunologie « Autoimmunité et Hypersensibilités », AP-HP, Hôpital Bichat-Claude Bernard, Paris, Paris, France, 5Paris, France, 6Service de médecine interne, Université Paris 13, AP-HP, Hôpital Jean Verdier, 93140, Bondy, France., Bondy, France, 7Obstetric and Gynecology of Brescia, Brescia, Italy, 8Rheumathology Unit, University of Brescia, Brescia, Italy, Brescia, Italy, 9Hemostase Poitiers, Poitiers, France, 10CHU poitiers, Poitiers, France, 11University Children's Hospital Ljubljana, Ljubljana, Slovenia, 12University Children's Hospital Ljubljana, Slovenie, Slovenia, 13Rheumatology, Brescia, Italy, 14Rheumatology, Milan, Italy, 15Bondy, France, 16Service d'hématologie biologique, Université Paris 13, AP-HP, Hôpital Jean Verdier, 93140, Bondy, France., Bondy, France
Hennepin County Medical Center
A High-Density Genome-Wide Association Study by the Sjögren’s Genetics Network Identifies Five Novel Susceptibility Loci for Primary Sjögren’s Syndrome and Confirms Association with MHC, IRF5, and BLK
Christopher J. Lessard1, John A. Ice1, Indra Adrianto1, Jennifer A. Kelly1, Roland Jonsson2, Gabor G. Illei3, Maureen Rischmueller4, Gunnel Nordmark5, Xavier Mariette6, Corinne Miceli-Richard6, Marie Wahren Herlenius7, Torsten Witte8, Michael T. Brennan9, Roald Omdal10, Timothy J. Vyse11, James A. Lessard12, Wan-Fai Ng13, Nelson L. Rhodus14, Barbara M. Segal15, R. Hal Scofield1, Benjamin A. Rybicki for ACCESS16, Juan-Manuel Anaya17, John B. Harley18, Courtney G. Montgomery1 and Kathy L. Moser19, 1Oklahoma Medical Research Foundation, Oklahoma City, OK, 2University of Bergen, Bergen, Norway, 3NIDCR/ NIH #10 1N110, Bethesda, MD, 4Queen Elizabeth Hospital, Adelaide, Australia, 5Department of Medical Sciences, Section of Rheumatology, Uppsala University, Uppsala, Sweden, 6Bicêtre University Hospital, Le Kremlin Bicêtre, France, 7Karolinska Institute, Stockholm, Sweden, 8Hannover Medical School, Hanover, Germany, 9Carolinas Medical Center, Charlotte, NC, 10Clinical Immunology Unit, Department of Internal Medicine, Stavanger University Hospital, Stavanger, Norway, 11Divisions of Genetics and Molecular Medicine and Immunology, King's College London, London, United Kingdom, 12Valley Bone & Joint Clinic, Grand Forks, ND, 13Musculoskeletal Research Group Institute of Cellular Medicine, Newcastle University, Newcastle, England, 14University of Minnesota, Minneapolis, MN, 15Hennepin County Medical Center, Minneapolis, MN, 16Henry Ford Hospital, Detroit, MI, 17Universidad del Rosario-Corporacion para Investigaciones Biologicas, Bogota, Colombia, 18Cincinnati Children's Hospital Medical Center and the US Department of Veterans Affairs Medical Center, Cincinnati, OH, 19Arthritis and Clinical Immunology Research Program, Oklahoma Medical Research Foundation, Oklahoma City, OK

Triple X Syndrome (47,XXX) Increases the Risk and Accelerates the Onset of Systemic Lupus Erythematosus and Sjögren's Syndrome: Support for a Gene-Dose Effect From the X Chromosome
Skyler P. Dillon1, Lydia Kao1, Kenneth M. Kaufman2, John A. Ice2, Roald Omdal3, Xavier Mariette4, Torsten Witte5, Gabor G. Illei6, Maureen Rischmueller7, Gunnel Nordmark8, Roland Jonsson9, Marie Wahren Herlenius10, Timothy J. Vyse11, Michael T. Brennan12, Benjamin A. Rybicki13, Wan-Fai Ng14, Barbara M. Segal15, Nelson L. Rhodus16, Joan T. Merrill2, Courtney G. Montgomery2, Christopher J. Lessard2, John B. Harley17, Kathy L. Moser18, Patrick M. Gaffney18 and R. Hal Scofield2, 1University of Oklahoma Health Sciences Center, Oklahoma City, OK, 2Oklahoma Medical Research Foundation, Oklahoma City, OK, 3Clinical Immunology Unit, Department of Internal Medicine, Stavanger University Hospital, Stavanger, Norway, 4Université Paris-Sud, Le Kremlin Bicetre, France, 5Hannover Medical School, Hanover, Germany, 6NIDCR/ NIH #10 1N110, Bethesda, MD, 7Queen Elizabeth Hospital, Adelaide, Australia, 8Department of Medical Sciences, Section of Rheumatology, Uppsala University, Uppsala, Sweden, 9University of Bergen, Bergen, Norway, 10CMM L8204 Karolinska Hosp, Stockholm, Sweden, 11Divisions of Genetics and Molecular Medicine and Immunology, King's College London, London, United Kingdom, 12Carolinas Medical Center, Charlotte, NC, 13Henry Ford Health System, Detroit, MI, 14Newcastle University, Newcastle upon Tyne, United Kingdom, 15Hennepin County Medical Center, Minneapolis, MN, 16University of Minnesota, Minneapolis, MN, 17Cincinnati Children's Hospital Medical Center and the US Department of Veterans Affairs Medical Center, Cincinnati, OH, 18Arthritis and Clinical Immunology Research Program, Oklahoma Medical Research Foundation, Oklahoma City, OK

Large-Scale, High-Density Genotyping Performed by the Sjögren’s Genetics Network Using the ImmunoChip Identifies PRKRA as a Novel Sjögren's Syndrome Susceptibility Locus and Confirms Associations with IRF5, BLK and MHC
Christopher J. Lessard1, Indra Adrianto1, John A. Ice1, Jennifer A. Kelly1, Roland Jonsson2, Gabor G. Illei3, Maureen Rischmueller4, Gunnel Nordmark5, Xavier Mariette6, Corinne Miceli-Richard6, Marie Wahren Herlenius7, Torsten Witte8, Michael T. Brennan9, Roald Omdal10, Patrick M. Gaffney11, James A. Lessard12, Wan-Fai Ng13, Nelson L. Rhodus14, Barbara M. Segal15, R. Hal Scofield1, Judith A. James16, Juan-Manuel Anaya17, John B. Harley18, Courtney Montgomery1 and Kathy L. Moser11, 1Oklahoma Medical Research Foundation, Oklahoma City, OK, 2University of Bergen, Bergen, Norway, 3NIDCR/ NIH #10 1N110, Bethesda, MD, 4Queen Elizabeth Hospital, Adelaide, Australia, 5Department of Medical Sciences, Section of Rheumatology, Uppsala University, Uppsala, Sweden, 6Bicêtre University Hospital, Le Kremlin Bicêtre, France, 7Karolinska Institute, Stockholm, Sweden, 8Hannover Medical School, Hanover, Germany, 9Carolinas Medical Center, Charlotte, NC, 10Clinical Immunology Unit, Department of Internal Medicine, Stavanger University Hospital, Stavanger, Norway, 11Arthritis and Clinical Immunology Research Program, Oklahoma Medical Research Foundation, Oklahoma City, OK, 12Valley Bone & Joint Clinic, Grand Forks, ND, 13Musculoskeletal Research Group Institute of Cellular Medicine, Newcastle University, Newcastle, England, 14University of Minnesota, Minneapolis, MN, 15Hennepin County Medical Center, Minneapolis, MN, 16Oklahoma Medical Research Foundation and Oklahoma University Health Sciences Center, Oklahoma City, OK, 17Universidad del Rosario-Corporacion para Investigaciones Biologicas, Bogota, Colombia, 18Cincinnati Children's Hospital Medical Center and the US Department of Veterans Affairs Medical Center, Cincinnati, OH

GI-REASONS: A Novel 6-Month, Prospective, Randomized, Open-Label, Blinded End Point (PROBE) Trial
Byron Cryer1, Chunming Li2, Lee S. Simon3, Gurkirpal Singh4, Martin Stillman5 and Manuela Berger2, 1University of Texas Southwestern Medical Center, Dallas, TX, 2Pfizer Inc, New York, NY, 3SDG LLC Consulting, West Newton, MA, 4Stanford University School of Medicine, Palo Alto, CA, 5Hennepin County Medical Center, Minneapolis, MN
Henry Ford Health System
Triple X Syndrome (47,XXX) Increases the Risk and Accelerates the Onset of Systemic Lupus Erythematosus and Sjögren's Syndrome: Support for a Gene-Dose Effect From the X Chromosome
Skyler P. Dillon1, Lydia Kao1, Kenneth M. Kaufman2, John A. Ice2, Roald Omdal3, Xavier Mariette4, Torsten Witte5, Gabor G. Illei6, Maureen Rischmueller7, Gunnel Nordmark8, Roland Jonsson9, Marie Wahren Herlenius10, Timothy J. Vyse11, Michael T. Brennan12, Benjamin A. Rybicki13, Wan-Fai Ng14, Barbara M. Segal15, Nelson L. Rhodus16, Joan T. Merrill2, Courtney G. Montgomery2, Christopher J. Lessard2, John B. Harley17, Kathy L. Moser18, Patrick M. Gaffney18 and R. Hal Scofield2, 1University of Oklahoma Health Sciences Center, Oklahoma City, OK, 2Oklahoma Medical Research Foundation, Oklahoma City, OK, 3Clinical Immunology Unit, Department of Internal Medicine, Stavanger University Hospital, Stavanger, Norway, 4Université Paris-Sud, Le Kremlin Bicetre, France, 5Hannover Medical School, Hanover, Germany, 6NIDCR/ NIH #10 1N110, Bethesda, MD, 7Queen Elizabeth Hospital, Adelaide, Australia, 8Department of Medical Sciences, Section of Rheumatology, Uppsala University, Uppsala, Sweden, 9University of Bergen, Bergen, Norway, 10CMM L8204 Karolinska Hosp, Stockholm, Sweden, 11Divisions of Genetics and Molecular Medicine and Immunology, King's College London, London, United Kingdom, 12Carolinas Medical Center, Charlotte, NC, 13Henry Ford Health System, Detroit, MI, 14Newcastle University, Newcastle upon Tyne, United Kingdom, 15Hennepin County Medical Center, Minneapolis, MN, 16University of Minnesota, Minneapolis, MN, 17Cincinnati Children's Hospital Medical Center and the US Department of Veterans Affairs Medical Center, Cincinnati, OH, 18Arthritis and Clinical Immunology Research Program, Oklahoma Medical Research Foundation, Oklahoma City, OK

Genome-Wide Association Study of African Americans Implicates Multiple Lung and Inflammatory Disease-Associated Loci in Sarcoidosis Susceptibility
Indra Adrianto1, Chee Paul Lin1, Jessica J. Hale1, Albert M. Levin2, Indrani Datta2, Ryan Parker1, Adam Adler1, Jennifer A. Kelly1, Kenneth M. Kaufman3, Christopher J. Lessard1, Kathy L. Moser4, Michael C. Iannuzzi5, Benjamin A. Rybicki2 and Courtney G. Montgomery1, 1Oklahoma Medical Research Foundation, Oklahoma City, OK, 2Henry Ford Health System, Detroit, MI, 3Arthritis and Clinical Immunology Research Program, Oklahoma Medical Research Foundation and US Department of Veterans Affairs Medical Center, Oklahoma City, OK, 4Arthritis and Clinical Immunology Research Program, Oklahoma Medical Research Foundation, Oklahoma City, OK, 5SUNY Upstate Medical University, Syracuse, NY
Henry Ford Hospital
A High-Density Genome-Wide Association Study by the Sjögren’s Genetics Network Identifies Five Novel Susceptibility Loci for Primary Sjögren’s Syndrome and Confirms Association with MHC, IRF5, and BLK
Christopher J. Lessard1, John A. Ice1, Indra Adrianto1, Jennifer A. Kelly1, Roland Jonsson2, Gabor G. Illei3, Maureen Rischmueller4, Gunnel Nordmark5, Xavier Mariette6, Corinne Miceli-Richard6, Marie Wahren Herlenius7, Torsten Witte8, Michael T. Brennan9, Roald Omdal10, Timothy J. Vyse11, James A. Lessard12, Wan-Fai Ng13, Nelson L. Rhodus14, Barbara M. Segal15, R. Hal Scofield1, Benjamin A. Rybicki for ACCESS16, Juan-Manuel Anaya17, John B. Harley18, Courtney G. Montgomery1 and Kathy L. Moser19, 1Oklahoma Medical Research Foundation, Oklahoma City, OK, 2University of Bergen, Bergen, Norway, 3NIDCR/ NIH #10 1N110, Bethesda, MD, 4Queen Elizabeth Hospital, Adelaide, Australia, 5Department of Medical Sciences, Section of Rheumatology, Uppsala University, Uppsala, Sweden, 6Bicêtre University Hospital, Le Kremlin Bicêtre, France, 7Karolinska Institute, Stockholm, Sweden, 8Hannover Medical School, Hanover, Germany, 9Carolinas Medical Center, Charlotte, NC, 10Clinical Immunology Unit, Department of Internal Medicine, Stavanger University Hospital, Stavanger, Norway, 11Divisions of Genetics and Molecular Medicine and Immunology, King's College London, London, United Kingdom, 12Valley Bone & Joint Clinic, Grand Forks, ND, 13Musculoskeletal Research Group Institute of Cellular Medicine, Newcastle University, Newcastle, England, 14University of Minnesota, Minneapolis, MN, 15Hennepin County Medical Center, Minneapolis, MN, 16Henry Ford Hospital, Detroit, MI, 17Universidad del Rosario-Corporacion para Investigaciones Biologicas, Bogota, Colombia, 18Cincinnati Children's Hospital Medical Center and the US Department of Veterans Affairs Medical Center, Cincinnati, OH, 19Arthritis and Clinical Immunology Research Program, Oklahoma Medical Research Foundation, Oklahoma City, OK

Evidence for CXCL16 As An Endothelial Progenitor Cell Chemotactic Factor
Jeffrey H. Ruth1, Takeo Isozaki1, M. Asif Amin1, Charles A. Lesch1, Ali S. Arbab2 and Alisa E. Koch3, 1University of Michigan, Ann Arbor, MI, 2Henry Ford Hospital, Detroit, MI, 3Department of Veteran's Affairs and University of Michigan, Ann Arbor, MI

Population-Based Incidence Estimates for Systemic Lupus Erythematosus in the USA, 2002-2005:  Results From the Michigan Lupus Epidemiology and Surveillance (MILES) Program
Emily C. Somers1, Wendy Marder1, Patricia C. Cagnoli1, Emily E. Lewis1, Peter DeGuire2, Caroline Gordon3, Charles G. Helmick4, Lu Wang1, Jeffrey J. Wing1, J. Patricia Dhar5, James C. Leisen6, W. Joseph McCune1 and MILES Group7, 1University of Michigan, Ann Arbor, MI, 2MI Dept of Community Health, Lansing, MI, 3University of Birmingham, Birmingham, United Kingdom, 4Centers for Disease Control and Prevention, Atlanta, GA, 5Wayne State University, Detroit, MI, 6Henry Ford Hospital, Detroit, MI, 7Ann Arbor, MI

Socioeconomic Status and Survival in Systemic Lupus Erythematosus:   Results From the Michigan Lupus Epidemiology and Surveillance (MILES) Program
Sarah M. Barnhart1, W. Joseph McCune1, Wendy Marder1, Patricia C. Cagnoli1, Emily E. Lewis1, Peter DeGuire2, C. Gordon3, Charles G. Helmick4, J. Patricia Dhar5, James C. Leisen6, Emily C. Somers1 and MILES Group7, 1University of Michigan, Ann Arbor, MI, 2MI Dept of Community Health, Lansing, MI, 3University of Birmingham, Birmingham, United Kingdom, 4Centers for Disease Control and Prevention, Atlanta, GA, 5Wayne State University, Detroit, MI, 6Henry Ford Hospital, Detroit, MI, 7Ann Arbor, MI
Hepatology, Pitié-Salpétrière
Serum Vitamin D Status and Polymorphisms in Vitamin D Metabolism-Related Genes in Chronic Hepatitis C Virus Infection with Extra-Hepatic Manifestations
Benjamin Terrier1, Frédéric Jehan2, Mona Monteanu3, Guillaume Geri4, David Saadoun5, Damien Sène4, Thierry Poynard3, Jean-Claude Souberbielle6 and Patrice Cacoub4, 1Pitié-Salpêtrière Hospital, Paris, France, 2INSERM U561, Paris, France, 3Hepatology, Pitié-Salpétrière, Paris, France, 4CHU Pitié-Salpêtrière, Paris, France, 5Department of Internal Medicine and Laboratory I3 “Immunology, Immunopathology, Immunotherapy”, UMR CNRS 7211, INSERM U959, Groupe Hospitalier Pitié-Salpetrière, Université Pierre et Marie Curie, Paris 6, Paris, France, Paris, France, 6Laboratoire d'Explorations Fonctionnelles, Necker, Paris, France
HFR Fribourg - Hôpital Cantonal
Subclinical Peripheral Synovitis Detected by ultrasound In Patients with Axial Spondyloarthritis
Pascal Zufferey1, Cecile Mouly Jr.1, Hans Rudolf Ziswiler2 and Jean Dudler3, 1Rheumatology, Lausanne, Switzerland, 2Rheumatology, Bern, Switzerland, 3HFR Fribourg - Hôpital Cantonal, Fribourg, Switzerland
HGR 36 CMN Manuel Ávila Camacho, Instituto Mexicano del Seguro Social
Comparison of the SF-36 Vs. Lupus Qol in Measuring Health-Related Quality of Life in Systemic Lupus Erythematosus Women with and without Activity
Claudia Mendoza-Pinto1, Mario Garcia-Carrasco Sr.1, Socorro Mendez-Martinez1, Oscar Pazarán1, Mario H. Cardiel2 and Aurelio Lopez-Colombo3, 1HGR 36 CMN Manuel Ávila Camacho, Instituto Mexicano del Seguro Social, Puebla, Mexico, 2Hospital, Morelia, Mexico, 3Delegación Estatal, Instituto Mexicano del Seguro Social, Puebla, Mexico
Higashi-hiroshima memorial Hospital
T-Cell-Related Cytokines Are Inhibited in Response to Tocilizumab in Patients with Rheumatoid Arthritis in Contrast with TNF-Inhibitor
Jiro Yamana1, Mitsuyoshi Iwahashi2, Motoaki Kim1, Rie Sasaki1, Keisuke Kobayashi1, Seizo Yamana1, Yusuke Sasaki3, Yasushi Shimonaka3 and Masahiko Mihara4, 1Higashi-hiroshima memorial Hospital, Hiroshima, Japan, 2Higashi-Hiroshima Memorial Hospital, Higashi-hiroshima, Japan, 3Chugai Pharmaceutical Co., Ltd., Kamakura, Kanagawa, Japan, 4Chugai Pharmaceutical Co., Ltd., Gotemba, Shizuoka, Japan
Higashi-Hiroshima Memorial Hospital
T-Cell-Related Cytokines Are Inhibited in Response to Tocilizumab in Patients with Rheumatoid Arthritis in Contrast with TNF-Inhibitor
Jiro Yamana1, Mitsuyoshi Iwahashi2, Motoaki Kim1, Rie Sasaki1, Keisuke Kobayashi1, Seizo Yamana1, Yusuke Sasaki3, Yasushi Shimonaka3 and Masahiko Mihara4, 1Higashi-hiroshima memorial Hospital, Hiroshima, Japan, 2Higashi-Hiroshima Memorial Hospital, Higashi-hiroshima, Japan, 3Chugai Pharmaceutical Co., Ltd., Kamakura, Kanagawa, Japan, 4Chugai Pharmaceutical Co., Ltd., Gotemba, Shizuoka, Japan

Validation of Algorithms Using Genome-Wide SNP Analysis for Prediction of Remission Criteria for Infliximab or Etanercept-Treated RA Patients Using Multiple Medical Cohorts
Tsukasa Matsubara1, Satoru Koyano2, Keiko Funahashi2, Takafumi Hagiwara1, Takako Miura1, Kosuke Okuda1, Takeshi Nakamura1, Akira Sagawa3, Takeo Sakurai4, Hiroaki Matsuno5, Tomomaro Izumihara6, Eisuke Shono7, Kou Katayama8, Toyomitsu Tsuchida9, Mitsuyoshi Iwahashi10, Tomomi Tsuru11 and Motohiro Oribe12, 1Matsubara Mayflower Hospital, Kato, Japan, 2Research Institute of Joint Diseases, Kobe, Japan, 3Sagawa Akira Rheumatology Clinic, Sapporo, Japan, 4Inoue Hospital, Takasaki, Japan, 5Matsuno Clinic for Rheumatic Diseases, Toyama, Japan, 6Izumihara Rheumatic and Medical Clinic, Kagoshima, Japan, 7Shono Rheumatology Clinic, Fukuoka, Japan, 8Katayama Orthopedic Rheumatology Clinic, Asahikawa, Japan, 9Tsuchida Clinic, Chiba, Japan, 10Higashi-Hiroshima Memorial Hospital, Higashi-hiroshima, Japan, 11PS Clinic, Fukuoka, Japan, 12Oribe Rheumatism and Internal Medicine Clinic, Oita, Japan

SNP Algorithms for Prediction of Efficacy and Adverse Events of Abatacept
Tsukasa Matsubara1, Satoru Koyano2, Keiko Funahashi2, Takafumi Hagiwara1, Takako Miura1, Kosuke Okuda1, Takeshi Nakamura1, Mitsuyoshi Iwahashi3, Tomomi Tsuru4, Shoichi Uchimura5 and Shigeru Honjo6, 1Matsubara Mayflower Hospital, Kato, Japan, 2Research Institute of Joint Diseases, Kobe, Japan, 3Higashi-Hiroshima Memorial Hospital, Higashi-hiroshima, Japan, 4PS Clinic, Fukuoka, Japan, 5Kanzaki Municipal General Hospital, Kanzaki, Japan, 6Honjo Rheumatism Clinic, Takaoka, Japan
Higashisumiyoshi Morimoto Hospital
Risk Factors for Osteoporosis in Patients with Rheumatoid Arthritis (TOMORROW STUDY)
Tadashi Okano1, Masahiro Tada1, Yuko Sugioka1, Kenji Mamoto2, Shigeyuki Wakitani1, Hiroaki Nakamura1 and Tatsuya Koike1, 1Osaka City University Medical School, Osaka, Japan, 2Higashisumiyoshi Morimoto Hospital, Osaka, Japan
Hikarigaoka Spellman Hospital
Efficacy Evaluation of Tocilizumab with the New ACR/EULAR Remission Criteria and DAS28-ESR
Tomonori Ishii, Department of Hematology and Rheumatology, Tohoku University Graduate School of Medicine, Sendai, Japan, Yasuhiko Hirabayashi, Hikarigaoka Spellman Hospital, Sendai, Japan and Michinoku Tocilizumab Study Group, Senndai
Hilltop Physicians, Inc.
A Phase 3 Placebo- and Oxycodone-Controlled Study of Tanezumab in Adults with Osteoarthritis
James Fidelholtz1, Marvin Tark2, Egilius Spierings3, Gernot Wolfram4, Karen Annis4, Michael D. Smith4, Mark T. Brown4 and Christine R. West5, 1Hilltop Physicians, Inc., Cincinnati, OH, 2Pain Solutions Treatment Centers, Marietta, GA, 3Brigham and Women's Hospital, Harvard Medical School, Boston, MA, 4Pfizer, Groton, CT, 5Pfizer, Williamston, MI
Hirosaki University Graduate School of Medicine
Treating to Target Matrix Metalloproteinase 3 Normalisation Together with Disease Activity Score Below 2.6 Yields Better Effects Than Each Alone In Rheumatoid Arthritis Patients: Treating to Twin Targets; T-4 Study
Yukitomo Urata1, Ryoko Uesato1, Dai Tanaka1, Yoshihide Nakamura2 and Shigeru Motomura2, 1Seihoku Chuo Hospital, Gosyogawara, Japan, 2Hirosaki University Graduate School of Medicine, Hirosaki, Japan
Hiroshima Clinic
Tocilizumab Improves Arterial Stiffness Compared with Abatacept In Patients with TNF Blockers-Resistant Active Rheumatoid Arthritis.An Open Label Randomized Controlled Trial
Kensuke Kume1, Kanzo Amano1, Susumu Yamada1 and Kazuhiko Hatta2, 1Hiroshima Clinic, Hiroshima, Japan, 2Hatta Clinic, Kure, Japan

Hiroshima University
Can Long-Term Use of Tocilizumab Induce Drug-Free Remission in Systemic Juvenile Idiopathic Arhtritis Refractory to Steroid Therapy?
Tomohiro Kubota1, Yuichi Yamasaki1, Junko Yasumura2, Naomi Kuwada3, Yukiko Nonaka1, Tomoko Takezaki1, Harumi Akaike1, Yasuhito Nerome1, Hiroyuki Imanaka1 and Syuji Takei1, 1Kagoshima University, Kagoshima City, Japan, 2Hiroshima University, Hiroshima City, Japan, 3Kumamoto University, Kumamoto City, Japan
HLA Laboratory
A Large-Scale Association Study Identified Multiple HLA-DRB1 Alleles Associated with Anti-Citrullinated Peptide Antibody Negative Rheumatoid Arthritis in Japanese
Chikashi Terao1, Koichiro Ohmura2, Yuta Kochi3, Katsunori Ikari4, Etsuko Maruya5, Masaki Katayama2, Kota Shimada6, Akira Murasawa7, Shigeru Honjo8, Kiyoshi Takasugi9, Keitaro Matsuo10, Kazuo Tajima10, Akari Suzuki3, Kazuhiko Yamamoto11, Shigeki Momohara4, Hisashi Yamanaka4, Ryo Yamada1, Hiroo Saji5, Fumihiko Matsuda1 and Tsuneyo Mimori2, 1Kyoto University, Kyoto, Japan, 2Kyoto Univ Grad School of Med, Kyoto, Japan, 3RIKEN, Yokohama, Japan, 4Institute of Rheumatology, Tokyo Women's Medical University, Tokyo, Japan, 5HLA Laboratory, Kyoto, Japan, 6Sagamihara, Japan, 7Niigata, Japan, 8Honjo Rheumatism Clinic, Kanzaki, Japan, 9Dohgo Spa Hospital, Matsuyama, Japan, 10Nagoya, Japan, 11Graduate School of Medicine, The University of Tokyo, Bunkyo-ku, Tokyo, Japan
Hoffmann-La Roche Inc
Correlation of [18f]FDG PET Assessments with Disease Activity and Markers of Inflammation in Patients with Early Rheumatoid Arthritis Following Initiation of Antirheumatic Therapy
Anne M. Roivainen1, Sannamari Hautaniemi1, Timo Möttönen1, Pirjo Nuutila1, Vesa Oikonen1, Riitta Parkkola1, Luminita Pricop2, Rudyard Ress2, Nicholas Seneca3, Marko Seppänen1 and Timo Yli-Kerttula1, 1Turku University Hospital, Turku, Finland, 2Hoffmann-La Roche Inc, Nutley, NJ, 3F. Hoffmann-La Roche Ltd., Switzerland
Hogeschool Leiden
A Randomised Comparison of Interactive and Conventional Education to Increase Adherence with a Dutch Physical Therapy Practice Guideline for Hip and Knee Osteoarthritis
Wfh Peter1, Ph van der Wees2, J. Verhoef3, Z. de Jong1, L. Vos1, Wkha Hilberdink4, M. Fiocco1 and Tpm VlietVlieland1, 1Leids University Medical Center, Leiden, Netherlands, 2The Royal Dutch Society of Physical Therapy (KNGF) Amsersfoort, CAPHRI Maastricht University, IQ Health Care, Nijmegen, Netherlands, 3Hogeschool Leiden, Leiden, Netherlands, 4Paramedical Center for Rheumatology and Rehabilitation, Groningen, Netherlands

Development of Quality Indicators for Physical Therapy in Hip and Knee Osteoarthritis
Wilfred FH Peter1, Ph van der Wees2, J. Verhoef3, Z. de Jong1, L. Vos1, Wkha Hilberdink4 and Tpm VlietVlieland1, 1Leids University Medical Center, Leiden, Netherlands, 2The Royal Dutch Society of Physical Therapy (KNGF) Amsersfoort, CAPHRI Maastricht University, IQ Healthcare, Nijmegen, Netherlands, 3Hogeschool Leiden, Leiden, Netherlands, 4Paramedical Center for Rheumatology and Rehabilitation, Groningen, Netherlands
Hokkaido University
Remission Induction by Etanercept (ETN) Plus Methotrexate (MTX) Combination Therapy Versus ETN Monotherapy in Patients with Active Rheumatoid Arthritis Despite MTX Treatment
Hideto Kameda1, Ukitaka Ueki2, Kazuyoshi Saito3, Shouhei Nagaoka4, Toshihiko Hidaka5, Tatsuya Atsumi6, Michishi Tsukano7, Tsuyoshi Kasama8, Shunichi Shiozawa9, Yoshiya Tanaka3, Katsuaki Kanbe10, Eri Sato11, Hisashi Yamanaka12 and Tsutomu Takeuchi1, 1Keio University School of Medicine, Tokyo, Japan, 2Rheumatic and Collagen Disease Center, Sasebo, Japan, 3U Occupa & Environ Hlth, Kitakyushu, Japan, 4Yokohama Minami Kyosai Hospital, Yokohama, Japan, 5Zenjinkai Shimin-No-Mori-Hospital, Miyazaki, Japan, 6Hokkaido University, Sapporo, Japan, 7Kumamoto Hospital, Kumamoto, Japan, 8Showa University School of Med, Shinagawa-ku Tokyo, Japan, 9Kobe University Graduate School of Health Science and Medicine/ TThe Center for Rheumatic Diseases, Kobe University Hospital, Kobe, Japan, 10Medical Center East, Tokyo Women's Medical University, Tokyo, Japan, 11Institute of Rheumatology, Tokyo Women's Medical University, Tokyo, Japan, 12Tokyo Women's Medical Univ, Shinjuku-ku , Tokyo, Japan
Hokkaido University Graduate School of Medicine
52-Week Results of Clinical, Radiographic and Pharmacokinetic Assessments: Golimumab, a Human Anti-TNF Monoclonal Antibody, Administered Subcutaneously Every Four Weeks in Patients with Active Rheumatoid Arthritis Despite Methotrexate Therapy
Yoshiya Tanaka, University of Occupational and Environmental Health, Japan, Kitakyushu, Fukuoka, Japan, Masayoshi Harigai, Tokyo Medical and Dental Univ, Tokyo, Japan, Tsutomu Takeuchi, Keio University School of Medicine, Tokyo, Japan, Hisashi Yamanaka, Institute of Rheumatology, Tokyo Women's Medical University, Tokyo, Japan, Naoki Ishiguro, Nagoya University, Graduate School & Faculty of Medicine, Nagoya, Aichi, Japan, Kazuhiko Yamamoto, Graduate School of Medicine, The University of Tokyo, Bunkyo-ku, Tokyo, Japan, Minoru Kanazawa, Director of Respiratory Center Professor of Respiratory, Medicine Saitama Medical University, Moroyama, Iruma-Gun, Saimata, Japan, Yoshinori Murakami, Janssen Pharmaceutical KK, Tokyo, Japan, Toru Yoshinari, Mitsubishi Tanabe Pharma Corporation, Osaka, Japan, Daniel G. Baker, Centocor R & D, a division of Johnson & Johnson Pharmaceutical Research and Development, LLC, Malvern, PA, Nobuyuki Miyasaka, Tokyo Medical and Dental University, Tokyo, Japan and Takao Koike, Hokkaido University Graduate School of Medicine, Sapporo, Japan

Golimumab, A Human Anti-TNF Monoclonal Antibody, Administered Subcutaneously Every Four Weeks As Monotherapy in Patients with Active Rheumatoid Arthritis Despite DMARD Therapy: 52-Week Results of Clinical, Radiographic and Pharmacokinetic Assessments
Tsutomu Takeuchi, Keio University School of Medicine, Tokyo, Japan, Masayoshi Harigai, Tokyo Medical and Dental Univ, Tokyo, Japan, Yoshiya Tanaka, University of Occupational and Environmental Health, Japan, Kitakyushu, Fukuoka, Japan, Hisashi Yamanaka, Institute of Rheumatology, Tokyo Women's Medical University, Tokyo, Japan, Naoki Ishiguro, Nagoya University, Graduate School & Faculty of Medicine, Nagoya, Aichi, Japan, Kazuhiko Yamamoto, Graduate School of Medicine, The University of Tokyo, Bunkyo-ku, Tokyo, Japan, Minoru Kanazawa, Director of Respiratory Center Professor of Respiratory, Medicine Saitama Medical University, Moroyama, Iruma-Gun, Saimata, Japan, Yoshinori Murakami, Janssen Pharmaceutical KK, Tokyo, Japan, Toru Yoshinari, Mitsubishi Tanabe Pharma Corporation, Osaka, Japan, Daniel G. Baker, Centocor R & D, a division of Johnson & Johnson Pharmaceutical Research and Development, LLC, Malvern, PA, Nobuyuki Miyasaka, Tokyo Medical and Dental University, Tokyo, Japan and Takao Koike, Hokkaido University Graduate School of Medicine, Sapporo, Japan
Holdsworth House Medical Practice
Inflammation Suppression Over 24 Weeks in Patients with Gouty Arthritis: Results From Two Phase-III Core and Extension Studies Comparing Canakinumab with Triamcinolone Acetonide
A. So1, R. Alten2, H. R. Schumacher3, T. Bardin4, M. Bloch5, D. Richard6, A. Karpov6, T. Kiechle6 and N. Schlesinger7, 1CHUV, Lausanne, Switzerland, 2Charité Teaching Hospital–Schlosspark-Klinik, Berlin, Germany, 3University of Pennsylvania and VA Medical Center, Philadelphia, PA, 4Hôpital Lariboisière, Paris, France, 5Holdsworth House Medical Practice, Sydney, Australia, 6Novartis Pharma AG, Basel, Switzerland, 7UMDNJ-Robert Wood Johnson Medical School, New Brunswick, NJ

Effect of IL-1β Inhibition with Canakinumab Compared to Triamcinolone Acetonide on Pain Intensity and New Flares in Gouty Arthritis Patients with Chronic Kidney Disease Stage 2-5
P. Sunkureddi1, T. Bardin2, R. Alten3, N. Schlesinger4, M. Bloch5, T. Kiechle6, G. Krammer6, A. Shpilsky7 and A. So8, 1Clear Lake Rheumatology Center, Nassau Bay, TX, 2Hôpital Lariboisière, Paris, France, 3Charité Teaching Hospital–Schlosspark-Klinik, Berlin, Germany, 4UMDNJ-Robert Wood Johnson Medical School, New Brunswick, NJ, 5Holdsworth House Medical Practice, Sydney, Australia, 6Novartis Pharma AG, Basel, Switzerland, 7Novartis Pharmaceutical Corporation, East Hanover, NJ, 8CHUV, Lausanne, Switzerland

Efficacy of Canakinumab on Re-Treatment in Gouty Arthritis Patients with Limited Treatment Options: 24-Week Results From β-RELIEVED and β-RELIEVED-II Studies
R. Alten1, A. So2, Alan J. Kivitz3, T. Bardin4, M. Bloch5, A. Gimona6, A. Widmer6, G. Krammer6, N. Schlesinger7 and H. R. Schumacher8, 1Charité Teaching Hospital–Schlosspark-Klinik, Berlin, Germany, 2CHUV, Lausanne, Switzerland, 3Altoona Center for Clinical Research, Duncansville, PA, 4Hôpital Lariboisière, Paris, France, 5Holdsworth House Medical Practice, Sydney, Australia, 6Novartis Pharma AG, Basel, Switzerland, 7UMDNJ-Robert Wood Johnson Medical School, New Brunswick, NJ, 8University of Pennsylvania and VA Medical Center, Philadelphia, PA
Honjo Rheumatism Clinic
A Large-Scale Association Study Identified Multiple HLA-DRB1 Alleles Associated with Anti-Citrullinated Peptide Antibody Negative Rheumatoid Arthritis in Japanese
Chikashi Terao1, Koichiro Ohmura2, Yuta Kochi3, Katsunori Ikari4, Etsuko Maruya5, Masaki Katayama2, Kota Shimada6, Akira Murasawa7, Shigeru Honjo8, Kiyoshi Takasugi9, Keitaro Matsuo10, Kazuo Tajima10, Akari Suzuki3, Kazuhiko Yamamoto11, Shigeki Momohara4, Hisashi Yamanaka4, Ryo Yamada1, Hiroo Saji5, Fumihiko Matsuda1 and Tsuneyo Mimori2, 1Kyoto University, Kyoto, Japan, 2Kyoto Univ Grad School of Med, Kyoto, Japan, 3RIKEN, Yokohama, Japan, 4Institute of Rheumatology, Tokyo Women's Medical University, Tokyo, Japan, 5HLA Laboratory, Kyoto, Japan, 6Sagamihara, Japan, 7Niigata, Japan, 8Honjo Rheumatism Clinic, Kanzaki, Japan, 9Dohgo Spa Hospital, Matsuyama, Japan, 10Nagoya, Japan, 11Graduate School of Medicine, The University of Tokyo, Bunkyo-ku, Tokyo, Japan

SNP Algorithms for Prediction of Efficacy and Adverse Events of Abatacept
Tsukasa Matsubara1, Satoru Koyano2, Keiko Funahashi2, Takafumi Hagiwara1, Takako Miura1, Kosuke Okuda1, Takeshi Nakamura1, Mitsuyoshi Iwahashi3, Tomomi Tsuru4, Shoichi Uchimura5 and Shigeru Honjo6, 1Matsubara Mayflower Hospital, Kato, Japan, 2Research Institute of Joint Diseases, Kobe, Japan, 3Higashi-Hiroshima Memorial Hospital, Higashi-hiroshima, Japan, 4PS Clinic, Fukuoka, Japan, 5Kanzaki Municipal General Hospital, Kanzaki, Japan, 6Honjo Rheumatism Clinic, Takaoka, Japan
Hope Hospital
One Year Randomised Controlled Trial of SEcond Line Agents in Myositis (SELAM): Late Additional immunosuppression is Ineffective in Patients Who Have Partially Responded to Steroids
Ernest Choy1, Patrick Gordon2, Beverley White-Alao2, Fowzia Ibrahim2, Anna Kowalczyk2, Alan Hakim3, George Kitas4, David A. Isenberg5, Bridget Griffiths6, Bryan Lecky7, Kuntal Chakravarty8, John Winer9, Katalin Danko10, Robert G. Cooper11 and David L. Scott2, 1Cardiff University, Cardiff, ENGLAND, United Kingdom, 2King's College London, London, United Kingdom, 3Whipps Cross University Hospital, London, United Kingdom, 4Dudley Group of Hospitals NHS Trust, Russells Hall Hospital, Dudley, West Midlands, UK, Dudley, United Kingdom, 5University College London, London, United Kingdom, 6Freeman Hospital, Newcastle Upon Tyne, United Kingdom, 7Walton Centre for Neurology and Neurosurgery (WCNN), Liverpool, 8Queen's Hospital/BHR NHS Trust, Romford, United Kingdom, 9The Queen Elizabeth Hospital, Birmingham, United Kingdom, 10University of Debrecen, Debrecen, Hungary, Debrecan, Hungary, 11Hope Hospital, Salford, United Kingdom

Clinical and Autoantibody Associations in Myositis Patients with Anti p155/140kDa Autoantibodies - a Multicenter European Study
Herman F. Mann1, Lenka Plestilova2, Hector Chinoy3, Robert G. Cooper4, Lara Dani5, Ingrid E. Lundberg5, Zoe Betteridge6, Neil J. McHugh7 and Jiri Vencovsky2, 1Institute of Rheumatology, 1st Faculty of Medicine, Charles University in Prague, Prague 2, Czech Republic, 2Institute of Rheumatology, Prague 2, Czech Republic, 3The University of Manchester, Manchester, United Kingdom, 4Hope Hospital, Salford, United Kingdom, 5Karolinska Institutet, Stockholm, Sweden, 6Royal National Hospital, Bath, United Kingdom, 7Royal National Hospital for Rheumatic Diseases, Bath, United Kingdom

Genome-Wide Association Study of Dermatomyositis Reveals Shared Genetic Risk Factors with Other Autoimmune Diseases
Frederick W. Miller1, Robert G. Cooper2, Jiri Vencovsky3, Lisa G. Rider4, Katalin Danko5, Lucy R. Wedderburn6, Ingrid E. Lundberg7, Lauren M. Pachman8, Ann M. Reed9, Steven R. Ytterberg9, Leonid Padyukov10, Albert Selva O'Callaghan11, Timothy Radstake12, David A. Isenberg13, Hector Chinoy14, William E. Ollier15, Terrance O'Hanlon16, Bo Peng17, Paul Scheet17, Annette T. Lee18, Janine Lamb14, Wei Chen17, Christopher Amos17, Peter K. Gregersen19 and Myositis Genetics Consortium20, 1NIH/NIEHS NIH Bldg 10 4-2330, Bethesda, MD, 2Hope Hospital, Salford, United Kingdom, 3Institute of Rheumatology, Prague 2, Czech Republic, 4NIEHS NIH, Bethesda, MD, 5University of Debrecen, Debrecen, Hungary, Debrecan, Hungary, 6University College London (UCL), London, United Kingdom, 7Karolinska Institutet, Stockholm, Sweden, 8Northwestern University Feinberg School of Medicine, Chicago, IL, 9Mayo Clinic, Rochester, MN, 10Rheumatology Unit, Karolinska Institutet, Stockholm, Sweden, 11Hospital Universitari General Vall d'Hebron, Barcelona, Spain, 12Geert Groote Plein 8, Nymegen, Netherlands, 13University College London, London, United Kingdom, 14Manchester, United Kingdom, 15Univ of Manchester Med School, Manchester, United Kingdom, 16NIH, Bethesda, MD, 17Houston, TX, 18Feinstein Institute Med Rsch, Manhasset, NY, 19Feinstein Institute Medical Reschearch, Manhasset, NY, 20Bethesda
Hopital Ambroise Pare
Sustained Improvement of Spinal Mobility, Physical Function, and Quality of Life in Patients with Ankylosing Spondylitis: 5-Year Results
Désirée van der Heijde1, Maxime A. Breban2, Dale G. Halter3, Gino DiVittorio4, Johan Bratt5, Fabrizio Cantini6, Sonja Kary7, L. Steven Brown8, Hartmut Kupper7, Tracy F. Nicholson9 and Philip J. Mease10, 1Department of Rheumatology, Leiden University Medical Center, Leiden, Netherlands, 2Hopital Ambroise Pare, Boulogne, France, 3Houston, TX, 4Mobile, AL, 5Karolinska Univ Hosp Huddinge, Stockholm, Sweden, 6Stabilimento Ospedaliero Misericordia, Prato, Italy, 7Abbott GmBH & Co KG, Ludwigshafen, Germany, 8Abbott Laboratories, Abbott Park, IL, 9Abbott Laboratories, 10Seattle Rheumatology Associate, Seattle, WA

Three Phenotype Profiles Are Revealed by Cluster Analysis in Early Inflammatory Back Pain Suggestive of Spondyloarthritis (SPA). Results From the DEvenir Des Spondyloarthropathies Indifferenciées Récentes (DESIR) Cohort
Maria-Antonietta D'Agostino, Versailles-Saint Quentin en Yvelines University- APHP, Ambroise-Paré Hospital, Boulogne-Billancourt, France, Philippe Aegerter, Versailles-Saint Quentin en Yvelines University- APHP, Ambroise-Paré Hospital,, Boulogne-Billancourt,, France, Maxime A. Breban, Hopital Ambroise Pare, Boulogne, France and Maxime Dougados, Paris-Descartes University, Paris, France

Highly Expressed HLA-B27 Accumulate in Subcellular Vesicular Compartments and Form Oligomers That Behave Differently From HLA-B7
Cindy Jeanty1, Adèle Sourisce1, Aurore Wielgosik1, Maxime A. Breban2 and Claudine André1, 1Institut Cochin, 75014 Paris, France, 2Hopital Ambroise Pare, Boulogne, France

A Reverse Interferon-γ Signature Is Shared by CD103+CD4+ Dendritic Cells From HLA-B27 Transgenic Rat and Macrophages From Ankylosing Spondylitis Patients
Ingrid Fert1, Nicolas Cagnard1, Simon Glatigny1, Franck Letourneur1, Sebastien Jacques1, Luiza Krause1, Robert A. Colbert2, Gilles Chiocchia1 and Maxime A. Breban3, 1Institut Cochin, 75014 Paris, France, 2NIAMS NIH, Bethesda, MD, 3Hopital Ambroise Pare, Boulogne, France

Transcriptomic Analysis of Monocytes and Monocyte-Derived Dendritic Cells (MD-DCs) Reveals Several Genes Differentially Regulated Between Ankylosing Spondylitis (AS) Patients and Healthy Controls
Alice Talpin1, Nelly Bonilla1, Félicie Costantino2, Franck Letourneur1, Sebastien Jacques1, Florent Dumont1, Henri-Jean Garchon2, Maxime A. Breban3 and Gilles Chiocchia1, 1Institut Cochin, 75014 Paris, France, 2Institut Cochin, Paris, France, 3Hopital Ambroise Pare, Boulogne, France
Hopital Avicenne, APHP
The Clinical Spectrum but Not the Evolution of Antisynthetase Syndrome Is Related to the Antisynthetase Antibody Specificity: A Retrospective Analysis of 142 Patients
Baptiste Hervier1, Hervé Devilliers2, Raluca Stanciu1, Eric Hachulla3, Yurdagul Uzunhan4, Bruno Wallaert5, Bruno Fautrel6, Bernard Fournie7, Lucile Musset8, Aude Rigolet1, Hilario Nunes4, Patrice Cacoub8, Daniel F. P. Adoue9, Zahir Amoura8, Mohamed Hamidou10 and Olivier Benveniste11, 1Pitie-Salpetriere Hospital, APHP, UPMC Paris VI, Paris, France, 2CHU Dijon, Dijon, France, 3Internal Medicine, Lille CEDEX, France, 4Hopital Avicenne, APHP, Bobigny, France, 5CHRU, Lille CEDEX, France, 6Université Pierre et Marie Curie - Paris 6 - Pitie Salpetriere University Hospital, Paris, France, 7CHU, Toulouse, France, 8CHU Pitié-Salpêtrière, Paris, France, 9CHU Toulouse Purpan, Toulouse, France, 10Service de médecine interne, Hôpital Universitaire de Nantes, Nantes, France, Nantes, France, 11Pitie-Salpetriere Hospital, Paris, France
Hopital Bicêtre
Germinal and Somatic Abnormalities of the TNFAIP3 Gene Support a Two-Hit Hypothesis of Lymphomagenesis in Autoimmune Diseases
Xavier Mariette1, Saida Boudaoud2, Gaetane Nocturne1, Thierry Lazure2, Joanne Nititham3, Kimberly E. Taylor4, Eric Hachulla5, Jean Jacques Dubost6, Jacques-Eric Gottenberg7, Lindsey A. Criswell8 and Corinne Miceli-Richard9, 1Bicêtre University Hospital, Le Kremlin Bicetre, France, 2INSERM U1012 - Université Paris XI, Le Kremlin Bicêtre, France, 3University of California, CA, 4University of California, San Francisco, San Francisco, CA, 5Internal Medicine, Lille CEDEX, France, 6CHU Gabriel Montpied, Clermont-Ferrand, France, 7Strasbourg University Hospital, Strasbourg, France, 8University of California San Francisco, San Francisco, CA, 9Hopital Bicêtre, Le Kremlin Bicêtre, France

Monoclonal Gammapathy Is Associated with Ten-Fold Risk of Hematologic Disorders in Primary Sjögren Syndrome
Anne-Laurence Tomi, Bicetre university hospital, Le Kremlin-Bicêtre, France, Raphaèle Seror, Bicetre university hospital, LE Kremlin-Bicetre, France, Stephan Pavy, Hopital Bicetre, Paris, France, Corinne Miceli-Richard, Hopital Bicêtre, Le Kremlin Bicêtre, France and Xavier Mariette, Université Paris-Sud, Le Kremlin Bicetre, France

BLK Polymorphisms Are Associated with Sjogren’s Syndrome Only in Patients with Anti-SSA Antibodies
Corinne Miceli-Richard1, Joanne Nititham2, Kimberly E. Taylor3, Céline Verstuyft1, Laurent Becquemont1, Ryad Tamouza4, Xavier Puechal5, Eric Hachulla6, Jacques-Eric Gottenberg7, Lindsey A. Criswell8 and Xavier Mariette9, 1Hopital Bicêtre, Le Kremlin Bicêtre, France, 2University of California, CA, 3University of California, San Francisco, San Francisco, CA, 4Paris, France, 5Le Mans General Hospital, Le Mans, France, 6Internal Medicine, Lille CEDEX, France, 7Strasbourg University Hospital, Strasbourg, France, 8University of California San Francisco, San Francisco, CA, 9Université Paris-Sud, Le Kremlin Bicetre, France

Serum IL-21 Is Increased and Associated with Higher Disease Activity and Higher Serum Levels of Markers of B-Cell Activation in Primary Sjögren's Syndrome
Jacques-Eric Gottenberg1, Ghada Alsaleh1, Corinne Miceli-Richard2, Raphaèle Seror3, Joelle Benessiano4, Valerie Devauchelle-Pensec5, Philippe Dieude6, Jean Jacques Dubost7, Anne-Laure Fauchais8, Vincent Goeb9, Eric Hachulla10, Pierre yves Hatron11, C. Larroche12, Véronique Le Guern13, Jacques Morel14, Aleth Perdriger15, Xavier Puechal16, Stephanie Rist17, Alain Saraux18, Damien Sène19, Jean Sibilia20, Karine Inamo21, Philippe Ravaud22 and Xavier Mariette23, 1Strasbourg University Hospital, Strasbourg, France, 2Hopital Bicêtre, Le Kremlin Bicêtre, France, 3Bicetre university hospital, LE Kremlin-Bicetre, France, 4Rheumatology, Paris Unervisity Hospital BICHAT, France, 5Brest Occidentale university, Brest, France, 6APHP, Hopital Bichat, Paris, France, 7CHU Gabriel Montpied, Clermont-Ferrand, France, 8Hospital, Limoges, France, 9Rheumatology, Rouen Unervisity Hospital, France, France, 10Internal Medicine, Lille CEDEX, France, 11Service de médecine interne, Hôpital Claude Huriez, Université Lille II, Lille, France, Paris, France, 12Hospital University Bobigny, France, 13Cochin Hospital, Paris, France, 14Hopital Lapeyronie, Montpellier, France, 15Hôpital Sud, Rennes, France, 16Le Mans General Hospital, Le Mans, France, 17Hospital University Orléans, France, 18CHU de la Cavale Blanche, Brest Cedex, France, 19Pitie-Salpetriere Hospital, Paris, France, 20Service de rhumatologie, Hôpitaux Universitaires de Strasbourg, Strasbourg, France, Strasbourg, France, 21Nihon Univ Hikarigoaka Hosp, Nerima-ku Tokyo, Japan, 22Hopital Hotel Dieu, Paris Descartes University, Paris, France, 23Université Paris-Sud, Le Kremlin Bicetre, France

Impact of Uveitis On the Phenotype of Patients with Recent Inflammatory Back Pain. Data From the DESIR Cohort
Daniel Wendling1, Clément Prati2, Christophe Demattei3, Corinne Miceli-Richard4, Jean-Pierre Daures3 and Maxime Dougados5, 1Minjoz University Hospital, Besancon, France, 2CHU J Minjoz, Besancon, France, 3CHU, Nimes, France, 4Hopital Bicêtre, Le Kremlin Bicêtre, France, 5Paris-Descartes University, Cochin Hospital, Paris, France
Hopital Bicetre
Monoclonal Gammapathy Is Associated with Ten-Fold Risk of Hematologic Disorders in Primary Sjögren Syndrome
Anne-Laurence Tomi, Bicetre university hospital, Le Kremlin-Bicêtre, France, Raphaèle Seror, Bicetre university hospital, LE Kremlin-Bicetre, France, Stephan Pavy, Hopital Bicetre, Paris, France, Corinne Miceli-Richard, Hopital Bicêtre, Le Kremlin Bicêtre, France and Xavier Mariette, Université Paris-Sud, Le Kremlin Bicetre, France

Less-Experienced Rheumatologists Can Improve Agreement in the Detection of Clinical Synovitis Through Consensus in Rheumatoid Arthritis (RA)
Peter Cheung1, Vincent Andre2, Natalie Balandraud3, Gerard H. Chales4, Isabelle Chary-Valckaneare5, Emmanuel Chatelus6, Emmanuelle Dernis2, Ghislaine Gill5, Melanie Gilson7, Sandrine Guis3, Thierry Marhadour8, Gael Mouterde9, Stephan Pavy10, Francois Pouyol11, Pascal Richette12, Adeline Ruyssen-Witrand13, Martin Soubrier14, Maxime Dougados15 and Laure Gossec16, 1Hospital Cochin, Paris, France, 2Centre Hospitalier, Le Mans, France, 3Hopital de la Conception, Marseilles, France, 4CHR - Hopital Sud, Rennes, France, 5Hopital de Brabois, Nancy, France, 6Hopital Hautepierre, Strasbourg, France, 7CH Grenoble Hopital Sud, Grenoble, France, 8CHU La Cavale Blanche, Brest, France, 9Hopital Lapeyronie, Montpellier, France, 10Hopital Bicetre, Paris, France, 11Hopital de Roger Salengro, Lille, France, 12Lariboisière Hospital, Paris, France, 13Hopitaux de Toulouse, Toulouse, France, 14CHU CLERMONT-FERRAND, Clermont-Ferrand, France, 15Paris-Descartes University, Cochin Hospital, Paris, France, 16Cochin Hospital, Paris, France
Hopital Bicetre, Université Paris Sud, AP-HP
A Whole-Blood Transcriptomic Signature Predicts Clinical Response to Rituximab in Rheumatoid Arthritis
Jeremie Sellam1, Sandrine Marion-Thore2, F. Dumont2, Franck Letourneur3, Stephanie Rouanet4, Yassine Taoufik5, Jean Sibilia6, Jacques G. Tebib7, Xavier Le Loët8, Bernard G. Combe9, Maxime Dougados10, Xavier Mariette11 and Gilles Chiocchia3, 1Hopital Saint-Antoine, Pierre et Marie Curie University Paris 6, AP-HP, 75012, France, 2INSERM U1016, Institut Cochin, Paris Descartes University, Paris, France, 3Institut Cochin, 75014 Paris, France, 4Roche, Neuilly sur Seine, France, 5Hopital Bicetre, Université Paris Sud, AP-HP, France, 6Service de rhumatologie, Hôpitaux Universitaires de Strasbourg, Strasbourg, France, Strasbourg, France, 7Centre Hosp Lyon Sud, Pierre Benite, France, 8Department of Rheumatology, Rouen University Hospital & Inserm 905, Institute for Biomedical Research, University of Rouen, Rouen, France, 9Hopital Lapeyronie, Montpellier, France, 10Paris-Descartes University, Paris, France, 11Université Paris-Sud, Le Kremlin Bicetre, France
Hopital Bichat
Body Mass Index Influences the Response to Infliximab in Ankylosing Spondylitis
Sébastien Ottaviani1, Yannick Allanore2, Florence Tubach3, Blandine Pasquet3, Olivier Meyer4 and Philippe Dieude5, 1APHP, Paris, France, 2Paris Descartes University, Rheumatology A department, Cochin Hospital, Paris, France, 3APHP, Hôpital Bichat, Paris, France, 4Hopital Bichat, Paris, France, 5APHP, Hopital Bichat, Paris, France

Evidence for the Contribution of the X Chromosome to Systemic Sclerosis Susceptibility: Association with the Functional IRAK1 196Phe/532Ser Haplotype
Philippe Dieude, Hopital Bichat, Paris, France, Matthieu Bouaziz, Evry- genopole, France, Gabriela Riemekasten, Charité University Hospital, German Rheumatology Research Center, a Leibniz Institute, Berlin, Germany, Paolo Airo, Brescia, Italy, Martina Müller, München, Germany, Daniele Cusi, Milano, Italy, Gilles Chiocchia, Institut Cochin, 75014 Paris, France, Catherine Boileau, Boulogne, France, Yannick Allanore, Paris Descartes University, Rheumatology A department, Cochin Hospital, Paris, France and Genesys Consortium, Paris
Hôpital Cantonal
Rheumatologist’s Expert Opinion Is An Important Determinant of Tumor Necrosis Factor Blocking Agent Prescription in Axial Spondyloarthritis: Results From the Swiss Clinical Quality Management Axial Spondyloarthritis Cohort
Almut Scherer1, Ulrich Weber2, Pascale Exer3, Juerg Bernhard4, Jean Dudler5, Giorgio Tamborrini6, Bettina Weiss2, Ruediger Mueller7, Beat A. Michel6, Rudolf O. Kissling2, Adrian Ciurea6 and on behalf of the SCQM Rheumatologists8, 1SCQM Foundation, Zurich, Switzerland, 2Balgrist University Hospital, Zurich, Switzerland, 3Private Rheumatology Practice, Basel, Switzerland, 4Buergerspital, Solothurn, Switzerland, 5Hôpital Cantonal, Fribourg, Switzerland, 6Department of Rheumatology, University Hospital, Zurich, Switzerland, 7Cantonal Hospital, St. Gallen, Switzerland, 8Scqm, Switzerland
Hopital Cochim
Churg–Strauss Syndrome: Description and Long-Term Follow-up of the 383 Patients Enrolled In the FVSG Cohort
Christian Pagnoux1, Chloe Comarmond2, Mehdi Khellaf3, Jean-Francois Cordier4, Mohamed Hamidou5, Jean-Francois Viallard6, Francois Maurier7, Philippe Delaval8, Boris Bienvenu9, Xavier Puechal10, Olivier Aumaître11, Marc Ruivard12, Alain Le Quellec13, Ramiro Cevallos14, Olivier Fain15, Bertrand Godeau3, Raphaèle Seror2, Alfred Mahr16, Pascal Cohen17, Luc Mouthon18, Loic Guillevin19 and French Vasculitis Study Group (FVSG)*, 1University of Toronto, Toronto, ON, 2Referral Center for Necrotizing Vasculitides, Hôpital Cochin, AP–HP, Université Paris–Descartes, Paris, France, 3Service de médecine interne, Université Paris Est Créteil, AP-HP, Hôpital Mondor Créteil, France, Creteil, France, 4Division of Pneumology, Hôpital Louis-Pradel, Hospices Civils de Lyon, Lyon 1, Lyon, France, 5Service de médecine interne, Hôpital Universitaire de Nantes, Nantes, France, Nantes, France, 6Division of internal Medicine, Hôpital Haut-Lévêque, Université Victor Segalen – Bordeaux 2, Centre Hospitalier Universitaire de Bordeaux, Bordeaux, Bordeaux, France, 7Division of internal Medicine, CHR Metz, Metz, Metz, France, 8Division of Pneumology, Centre Hospitalier Régional Universitaire de Rennes, Rennes, Rennes, France, 9Division of Internal Medicine, Centre Hospitalier Régional Universitaire de Caen, Côte de Nacre, Caen, Caen, France, 10Le Mans General Hospital, Le Mans, France, 11Division of internal Medicine, Centre Hospitalier Universitaire, Hôpital Gabriel Montpied, Clermont–Ferrand, Clermont–Ferrand, France, 12Medicine, Centre Hospitalier Universitaire, Hôpital Gabriel Montpied, Clermont–Ferrand, Clermont–Ferrand, France, 13Division of internal Medicine, Hôpital Saint-Eloi, Centre Hospitalier Universitaire de Montpellier, Montpellier, Montpellier, France, 14CH Compiegne, Compiegne, France, 15Service de médecine interne, Université Paris 13, AP-HP, Hôpital Jean Verdier, 93140, Bondy, France., Bondy, France, 16Hospital Saint-Louis, Paris, France, 17Service de médecine interne, Centre de Références des Vascularites, Université Paris Descartes, APHP, Hôpital Cochin, 75005 Paris, France., Paris, France, 18Hopital Cochim, Paris, France, 19Cochin University Hospital, Paris, France

Are Patients with ANCA-Associated Vasculitis Entered In Clinical Trials Representative of Patients Followed In Observational Cohorts?
Christian Pagnoux1, Simon Carette2, Nader A. Khalidi3, David Cuthberston4, Paul R. Fortin5, Gary S. Hoffman6, Carol A. Langford7, Paul A. Monach8, Luc Mouthon9, Philip Seo10, Ulrich Specks11, Steven R. Ytterberg11, Peter A. Merkel12, Loic Guillevin13, French Vasculitis Study Group (FVSG)14 and The Vcrc8, 1University Health Network, Toronto, Canada, Toronto, ON, 2Toronto Western Hospital, Toronto, ON, 3McMaster University, Hamilton, ON, 4University of South Florida, Tampa, FL, 5Toronto Western Hospital and University of Toronto, Toronto, ON, 6Cleveland Clinic Found A50, Cleveland, OH, 7Cleveland Clinic, Cleveland, OH, 8Boston University, Boston, MA, 9Hopital Cochim, Paris, France, 10Johns Hopkins Vasculitis Center, Baltimore, MD, 11Mayo Clinic, Rochester, MN, 12Boston University School of Medicine, Boston, MA, 13Cochin University Hospital, Paris, France, 14Paris, France

Churg–Strauss Syndrome: Analysis of 58 patients’ Relapses and Outcomes
Maxime Samson, Hôpital Cochin, University Paris Descartes, Paris, France, Camillo Ribi, Hôpital Universitaire Cantonal de Genève, Geneve, Switzerland, Pascal Cohen, Service de médecine interne, Centre de Références des Vascularites, Université Paris Descartes, APHP, Hôpital Cochin, 75005 Paris, France., Paris, France, Marc Stern, Hôpital Foch, Suresnes, France, Christian Pagnoux, University of Toronto, Toronto, ON, Jean-Francois Cordier, Division of Pneumology, Hôpital Louis-Pradel, Hospices Civils de Lyon, Lyon 1, Lyon, France, Luc Mouthon, Hopital Cochim, Paris, France and Loic Guillevin, Cochin University Hospital, Paris, France
Hôpital Cochin
Remission According to Different Composite Disease Activity Indices in Biologic-naïve Patients with Rheumatoid Arthritis Treated with Abatacept or Infliximab Plus Methotrexate
Josef S. Smolen1, Maxime Dougados2, Corine Gaillez3, Coralie Poncet4, Manuela Le Bars3, Monica Mody5 and Michael H. Schiff6, 1Medical University of Vienna and Hietzing Hospital, Vienna, Austria, 2Hôpital Cochin, Paris, France, 3Bristol-Myers Squibb, Rueil Malmaison, France, 4Docs International, Sévres, France, 5Bristol-Myers Squibb, Princeton, NJ, 6University of Colorado, Denver, CO
Hopital Cochin
Evaluation of the Impact of Recurrent Ischemic Digital Ulcers on Hand Disability in Patients with Systemic Sclerosis (ECLIPSE). Report of the Cohort At the Time of Inclusion
Luc Mouthon, Hopital Cochin, Paris, France, Patrick Carpentier, CHU Grenoble, Grenoble, France, Catherine Lok, Amiens Hospital, France, Eve Puzenat, Besançon, Besançon, France, Pierre Clerson, Orgametrie, Roubaix, Virginie Gressin, Actelion France, Paris, France and Marie-Aleth Richard, Marseille, Paris, France

Demonstration of the Symptomatic and Structural Effect of Methotrexate in Daily Practice As the First RA-DMARD Despite Its Sub-Optimal Use: Results From the ESPOIR Early Synovitis Cohort
Cécile Gaujoux-Viala, Paris 6 – Pierre et Marie Curie University; Rheumatology, Pitié-Salpêtrière Hospital, Paris, France, Simon Paternotte, Hopital Cochin, Paris, France, Bernard G. Combe, Hopital Lapeyronie, Montpellier, France and Maxime Dougados, Paris-Descartes University, Paris, France

Development and Content Validity of the Hand Disability in Systemic Sclerosis—Digital Ulcers (HDISS-DU) Scale
Dinesh Khanna1, Serge Poiraudeau2, Heather Gelhorn3, Elke Hunsche4, Kelly Papadakis4, Loic Perchenet4, Maria Stoeckl Mattera5, Margaret Vernon5 and Luc Mouthon2, 1University of Michigan, Ann Arbor, MI, 2Hopital Cochin, Paris, France, 3United BioSource Corporation, Golden, CO, 4Actelion Pharmaceuticals Ltd, Allschwil, Switzerland, 5United BioSource Corporation, Bethseda, Bethesda, US., MD

Creation of A COHORT of French PATIENTS with CHRONIC RECURRENT Multifocal OSTEITIS : PRELIMINARY RESULTS
Julien Wipff1, M.-A. Dumitrescu2, Mathie Lorrot3, Albert Faye2, S. lacassagne-Compeyrot4, B. Bader Meunier4, R. Mouy4, Carine H. Wouters5, Marine Desjonqueres6, S. Jean7, V. Despert7, A. Duquesne6, I. Lemelle8, P. Pillet9, M. Grall-Lerosey10, Pierre Quartier11 and Chantal Job-Deslandre12, 1Paris descartes Universityn Rheumatology A, Cochin Hospital, Paris, France, 2Paris, France, 3Paediatry, Robert Debré hospital, Paris, France, 4University Paris Descartes, Paediatry, Necker hospital, Paris, France, 5Paediatric Rheumatology Internationsl Trials Organization, Leuven, Belgium, 6Hopital Femme Mere Enfant, Groupement Hospitalier Est, Lyon, France, 7Paediatry, CHU, Rennes, France, 8Paediatry, CHU, Nancy, France, 9Paediatry, CHU, Bordeaux, France, 10Paediatry, CHU, Rouen, France, 11Hôpital Necker-Enfants Malades, Paris, France, 12Hopital Cochin, Paris Cedex 14, France
Hôpital Cochin, University Paris Descartes
Churg–Strauss Syndrome: Analysis of 58 patients’ Relapses and Outcomes
Maxime Samson, Hôpital Cochin, University Paris Descartes, Paris, France, Camillo Ribi, Hôpital Universitaire Cantonal de Genève, Geneve, Switzerland, Pascal Cohen, Service de médecine interne, Centre de Références des Vascularites, Université Paris Descartes, APHP, Hôpital Cochin, 75005 Paris, France., Paris, France, Marc Stern, Hôpital Foch, Suresnes, France, Christian Pagnoux, University of Toronto, Toronto, ON, Jean-Francois Cordier, Division of Pneumology, Hôpital Louis-Pradel, Hospices Civils de Lyon, Lyon 1, Lyon, France, Luc Mouthon, Hopital Cochim, Paris, France and Loic Guillevin, Cochin University Hospital, Paris, France
Hopital de Brabois
Less-Experienced Rheumatologists Can Improve Agreement in the Detection of Clinical Synovitis Through Consensus in Rheumatoid Arthritis (RA)
Peter Cheung1, Vincent Andre2, Natalie Balandraud3, Gerard H. Chales4, Isabelle Chary-Valckaneare5, Emmanuel Chatelus6, Emmanuelle Dernis2, Ghislaine Gill5, Melanie Gilson7, Sandrine Guis3, Thierry Marhadour8, Gael Mouterde9, Stephan Pavy10, Francois Pouyol11, Pascal Richette12, Adeline Ruyssen-Witrand13, Martin Soubrier14, Maxime Dougados15 and Laure Gossec16, 1Hospital Cochin, Paris, France, 2Centre Hospitalier, Le Mans, France, 3Hopital de la Conception, Marseilles, France, 4CHR - Hopital Sud, Rennes, France, 5Hopital de Brabois, Nancy, France, 6Hopital Hautepierre, Strasbourg, France, 7CH Grenoble Hopital Sud, Grenoble, France, 8CHU La Cavale Blanche, Brest, France, 9Hopital Lapeyronie, Montpellier, France, 10Hopital Bicetre, Paris, France, 11Hopital de Roger Salengro, Lille, France, 12Lariboisière Hospital, Paris, France, 13Hopitaux de Toulouse, Toulouse, France, 14CHU CLERMONT-FERRAND, Clermont-Ferrand, France, 15Paris-Descartes University, Cochin Hospital, Paris, France, 16Cochin Hospital, Paris, France
Hopital de la Conception
Late Apoptotic Bodies Mediates Sterile Inflammation in Vitro and In Vivo Via IL-1alpha
Yael Berda-Haddad1, Stéphane Robert1, Paul Salers1, Leila Zekraoui2, Catherine Farnarier3, Charles A. Dinarello4, Françoise Dignat-George1 and Gilles Kaplanski1, 1INSERM U608, Marseille, France, 2Faculté de Médecine-Timone, Marseille, France, 3Hopital de la Conception, Marseille, France, 4Denver, CO

Less-Experienced Rheumatologists Can Improve Agreement in the Detection of Clinical Synovitis Through Consensus in Rheumatoid Arthritis (RA)
Peter Cheung1, Vincent Andre2, Natalie Balandraud3, Gerard H. Chales4, Isabelle Chary-Valckaneare5, Emmanuel Chatelus6, Emmanuelle Dernis2, Ghislaine Gill5, Melanie Gilson7, Sandrine Guis3, Thierry Marhadour8, Gael Mouterde9, Stephan Pavy10, Francois Pouyol11, Pascal Richette12, Adeline Ruyssen-Witrand13, Martin Soubrier14, Maxime Dougados15 and Laure Gossec16, 1Hospital Cochin, Paris, France, 2Centre Hospitalier, Le Mans, France, 3Hopital de la Conception, Marseilles, France, 4CHR - Hopital Sud, Rennes, France, 5Hopital de Brabois, Nancy, France, 6Hopital Hautepierre, Strasbourg, France, 7CH Grenoble Hopital Sud, Grenoble, France, 8CHU La Cavale Blanche, Brest, France, 9Hopital Lapeyronie, Montpellier, France, 10Hopital Bicetre, Paris, France, 11Hopital de Roger Salengro, Lille, France, 12Lariboisière Hospital, Paris, France, 13Hopitaux de Toulouse, Toulouse, France, 14CHU CLERMONT-FERRAND, Clermont-Ferrand, France, 15Paris-Descartes University, Cochin Hospital, Paris, France, 16Cochin Hospital, Paris, France
Hopital de la Pitie
Immunosuppressants Reduce Venous Thrombosis Relapses in Behçet‘s Disease
anne Claire Desbois1, Bertrand Wechsler2, Jean-Charles Piette3, Du Boutin1, Zahir Amoura4, Fabien Koskas1, Patrice Cacoub4 and David Saadoun5, 1Department of Internal Medicine and 2Laboratory I3 « Immunology, Immunopathology, Immunotherapy », UMR CNRS 7211, INSERM U959, Groupe Hospitalier Pitié-Salpetrière, Université Pierre et Marie Curie, Paris 6, Paris, France, Paris, France, 2Hopital de la Pitie, Paris, France, 3Paris, 4CHU Pitié-Salpêtrière, Paris, France, 5Department of Internal Medicine and Laboratory I3 “Immunology, Immunopathology, Immunotherapy”, UMR CNRS 7211, INSERM U959, Groupe Hospitalier Pitié-Salpetrière, Université Pierre et Marie Curie, Paris 6, Paris, France, Paris, France
Hopital de la Source
Maintenance of Antifracture Efficacy Over 10 Years with Strontium Ranelate in Postmenopausal osteoporosis 
J.-Y. Reginster, University of Liège, Liège, Belgium, Jean-Marc Kaufman, Ghent University Hospital, Ghent, Belgium, Jean-Pierre Devogelaer, St-Luc University Hospital, Brussels, Belgium, Claude-Laurent Benhamou, Hopital de la Source, Orleans and C. Roux, Paris Descartes University, Paris, France
Hopital de Roger Salengro
Less-Experienced Rheumatologists Can Improve Agreement in the Detection of Clinical Synovitis Through Consensus in Rheumatoid Arthritis (RA)
Peter Cheung1, Vincent Andre2, Natalie Balandraud3, Gerard H. Chales4, Isabelle Chary-Valckaneare5, Emmanuel Chatelus6, Emmanuelle Dernis2, Ghislaine Gill5, Melanie Gilson7, Sandrine Guis3, Thierry Marhadour8, Gael Mouterde9, Stephan Pavy10, Francois Pouyol11, Pascal Richette12, Adeline Ruyssen-Witrand13, Martin Soubrier14, Maxime Dougados15 and Laure Gossec16, 1Hospital Cochin, Paris, France, 2Centre Hospitalier, Le Mans, France, 3Hopital de la Conception, Marseilles, France, 4CHR - Hopital Sud, Rennes, France, 5Hopital de Brabois, Nancy, France, 6Hopital Hautepierre, Strasbourg, France, 7CH Grenoble Hopital Sud, Grenoble, France, 8CHU La Cavale Blanche, Brest, France, 9Hopital Lapeyronie, Montpellier, France, 10Hopital Bicetre, Paris, France, 11Hopital de Roger Salengro, Lille, France, 12Lariboisière Hospital, Paris, France, 13Hopitaux de Toulouse, Toulouse, France, 14CHU CLERMONT-FERRAND, Clermont-Ferrand, France, 15Paris-Descartes University, Cochin Hospital, Paris, France, 16Cochin Hospital, Paris, France
Hôpital Edouard Herriot
Extended Safety Observations From Denosumab Administration in Postmenopausal Women From the FREEDOM and FREEDOM Extension Trials
J. P. Brown1, H. G. Bone2, R. Chapurlat3, C. Libanati4, M. L. Brandi5, E. Czerwinski6, M.-A. Krieg7, Z. Man8, D. Mellström9, S. C. Radominski10, J.-Y. Reginster11, H. Resch12, J. A. Román Ivorra13, C. Roux14, N. S. Daizadeh4, A. Grauer4, S. R. Cummings15 and S. Papapoulos16, 1CHUQ-CHUL Research Centre, Laval University, Quebec City, QC, 2Michigan Bone & Mineral Clinic, Detroit, MI, 3Hôpital Edouard Herriot, Lyon, France, 4Amgen Inc., Thousand Oaks, CA, 5University of Florence, Florence, Italy, 6Krakow Medical Center, Krakow, Poland, 7University Hospital of Lausanne, Lausanne, Switzerland, 8Centro TIEMPO, Buenos Aires, Argentina, 9Sahlgrenska University Hospital, Göteborg, Sweden, 10Universidade Federal do Paraná, Curitiba, Brazil, 11University of Liège, Liège, Belgium, 12St. Vincent Hospital, Vienna, Austria, 13Hospital Universitario La Fe, Valencia, Spain, 14Paris Descartes University, Paris, France, 15San Francisco Coordinating Center, CPMC Research Institute, San Francisco, CA, 16Leiden University Medical Center, Leiden, Netherlands

Six Years of Denosumab Treatment in Postmenopausal Women with Osteoporosis:  Results From the First Three Years of the FREEDOM Extension
J.P. Brown1, H. G. Bone2, R. Chapurlat3, N. Franchimont4, M. L. Brandi5, E. Czerwinski6, M.-A. Krieg7, Z. Man8, D. Mellström9, S. C. Radominski10, J.-Y. Reginster11, H. Resch12, J. A. Román Ivorra13, C. Roux14, N. S. Daizadeh4, M. L. Geller4, S. Smith4, R.B. Wagman4, S. R. Cummings15 and S. Papapoulos16, 1CHUQ-CHUL Research Centre, Laval University, Quebec City, QC, 2Michigan Bone & Mineral Clinic, Detroit, MI, 3Hôpital Edouard Herriot, Lyon, France, 4Amgen Inc., Thousand Oaks, CA, 5University of Florence, Florence, Italy, 6Krakow Medical Center, Krakow, Poland, 7University Hospital of Lausanne, Lausanne, Switzerland, 8Centro TIEMPO, Buenos Aires, Argentina, 9Sahlgrenska University Hospital, Göteborg, Sweden, 10Universidade Federal do Paraná, Curitiba, Brazil, 11University of Liège, Liège, Belgium, 12St. Vincent Hospital, Vienna, Austria, 13Hospital Universitario La Fe, Valencia, Spain, 14Paris Descartes University, Paris, France, 15San Francisco Coordinating Center, CPMC Research Institute, and UCSF, San Francisco, CA, 16Leiden University Medical Center, Leiden, Netherlands
Hopital Femme Mere Enfant, Groupement Hospitalier Est
Demographic and Genetic Results From the EUROFEVERS/EUROTRAPS Consortia in the Largest Series of Patients with TRAPS Yet Reported
Helen J. Lachmann1, Antonella Meini2, Isabelle Touitou3, Laura Obici4, Martina Finetti5, Kirsten Minden6, Luca Cantarini7, Marine Desjonqueres8, Joost Frenkel9, Isabelle Kone-Paut10, Olga Vougiouka11, Maria Jesus Rua Elorduy12, Nicola Ruperto13, Patricia Woo1 and Marco Gattorno14, 1University College London Medical School, London, United Kingdom, 2Dipartimento di Pediatria, University of Brescia, Brescia, Italy, 3CHU Montpellier - Hôpital Arnaud de Villeneuve, Montpellier, France, 4IRCCS Policlinico S. Matteo, Pavia, Italy, 5IRCCS Istituto G. Gaslini, Genova, Italy, 6Charite, Berlin, Germany, 7Policlinico le Scotte, Sienna, Italy, 8Hopital Femme Mere Enfant, Groupement Hospitalier Est, Lyon, France, 9University Medical Center Utrecht, Utrecht, Netherlands, 10CHU Le Kremlin Bicetre, Paris, France, 11P. A. Kyriakou Childrens Hospital of Athens University, Athens, Greece, 12Hospital de Cruces, Barakaldo, Spain, 13Paediatric Rheumatology International Trials Organisation – IRCCS [PRINTO], Genova, Italy, 14G Gaslini Institute, Genoa, Italy

Creation of A COHORT of French PATIENTS with CHRONIC RECURRENT Multifocal OSTEITIS : PRELIMINARY RESULTS
Julien Wipff1, M.-A. Dumitrescu2, Mathie Lorrot3, Albert Faye2, S. lacassagne-Compeyrot4, B. Bader Meunier4, R. Mouy4, Carine H. Wouters5, Marine Desjonqueres6, S. Jean7, V. Despert7, A. Duquesne6, I. Lemelle8, P. Pillet9, M. Grall-Lerosey10, Pierre Quartier11 and Chantal Job-Deslandre12, 1Paris descartes Universityn Rheumatology A, Cochin Hospital, Paris, France, 2Paris, France, 3Paediatry, Robert Debré hospital, Paris, France, 4University Paris Descartes, Paediatry, Necker hospital, Paris, France, 5Paediatric Rheumatology Internationsl Trials Organization, Leuven, Belgium, 6Hopital Femme Mere Enfant, Groupement Hospitalier Est, Lyon, France, 7Paediatry, CHU, Rennes, France, 8Paediatry, CHU, Nancy, France, 9Paediatry, CHU, Bordeaux, France, 10Paediatry, CHU, Rouen, France, 11Hôpital Necker-Enfants Malades, Paris, France, 12Hopital Cochin, Paris Cedex 14, France
Hôpital Femme-Mère-Enfant
Mycophenolate Mofetil in Children with Lupus: Clinical Findings in Favour of Therapeutic Drug Monitoring
Brigitte Bader-Meunier1, Camille Jurado2, Bruno Ranchin3, Stéphane Decramer4, Michel Fischbach5, Etienne Berard6 and Franck Saint Marcoux2, 1Hôpital Necker, Paris, France, 2INSERM UMR –S850, Limoges, France, 3Hôpital Femme-Mère-Enfant, Lyon, France, 4hôpital Purpan, Toulouse, France, 5Hôpital Hautepierre, Strasbourg, France, 6Hôpital Lenval, Nice, France
Hôpital Foch
Churg–Strauss Syndrome: Analysis of 58 patients’ Relapses and Outcomes
Maxime Samson, Hôpital Cochin, University Paris Descartes, Paris, France, Camillo Ribi, Hôpital Universitaire Cantonal de Genève, Geneve, Switzerland, Pascal Cohen, Service de médecine interne, Centre de Références des Vascularites, Université Paris Descartes, APHP, Hôpital Cochin, 75005 Paris, France., Paris, France, Marc Stern, Hôpital Foch, Suresnes, France, Christian Pagnoux, University of Toronto, Toronto, ON, Jean-Francois Cordier, Division of Pneumology, Hôpital Louis-Pradel, Hospices Civils de Lyon, Lyon 1, Lyon, France, Luc Mouthon, Hopital Cochim, Paris, France and Loic Guillevin, Cochin University Hospital, Paris, France
Hopital Gui de Chauliac
Etanercept Induces a Decrease in Left Ventricular Mass in Patients with Rheumatoid Arthritis
Claire Daien1, Pierre Fesler1, Vincent Daien2, Guilhem du Cailar1, Anne-Marie Dupuy1, Jean-Paul Cristol1, Jean Ribstein1, Bernard G. Combe1 and Jacques Morel1, 1Hopital Lapeyronie, Montpellier, France, 2Hopital Gui de Chauliac, Montpellier, France
Hôpital Haut-Lévêque
Active Immunization Against IFNα with IFN-Kinoid in SLE Patients Is Safe, Immunogenic and Induces Down-Regulation of IFN-Mediated Genes
Frédéric A. Houssiau1, Raskov Rashkov2, Eric Hachulla3, Estibaliz Lazaro4, Christian Jorgensen5, François Spertini6, Xavier Mariette7, Géraldine Grouard-Vogel8, Bernard Fanget8, Olivier Dhellin8, Bernard Lauwerys1 and Pierre Vandepapelière8, 1Université catholique de Louvain, Brussels, Belgium, 2MHAT Sveti Ivan Rilski, Sofia, Bulgaria, 3Internal Medicine, Lille CEDEX, France, 4Hôpital Haut-Lévêque, Pessac, France, 5Hospital Lapeyronie, Montpellier, France, 6CHU Vaudois, Lausanne, Switzerland, 7Université Paris-Sud, Le Kremlin Bicetre, France, 8NEOVACS SA, Paris, France
Hopital Hautepierre
Reactive Hyperemia Index Is Associated with Macroangiopathy and Lung Involvement in Systemic Scleroderma
Alain Meyer1, Bernard Geny2, Emmanuel Chatelus3, Olivier Rouyer2, Arnaud Theulin4, Christelle Sordet4, Rose-Marie Javier4, Jean Sibilia5 and Jacques-Eric Gottenberg6, 1Hautepierre Strasbourg university, Strasbourg, France, 2Medicine faculty, Strasbourg university, Strasbourg, France, 3Hopital Hautepierre, Strasbourg, France, 4Hautepierre Strasbourg Hospital University, Strasbourg, France, 5CHU Hautepierre, Strasbourg, France, 6Strasbourg University Hospital, Strasbourg, France

Salivary Gland Epithelial Cells Are Capable to Directly Induce the Differentiation of IL-21-Secreting Follicular Helper CD4 T Cells in Primary Sjögren’s Syndrome
Yazhuo Gong1, Ghada Alsaleh2, Emmanuel Chatelus3, Christelle Sordet4, Jean Sibilia5, Dominique Wachsmann1 and Jacques-Eric Gottenberg2, 1EA 44 38, Strasbourg, France, 2Strasbourg University Hospital, Strasbourg, France, 3Hopital Hautepierre, Strasbourg, France, 4Hautepierre Strasbourg Hospital University, Strasbourg, France, 5CHU Hautepierre, Strasbourg, France

Campylobacter Fetus Infection In Three Patients Treated with Rituximab for Rheumatoid Arthritis
Alain Meyer1, Arnaud Theulin2, Emmanuel Chatelus3, Christelle Sordet2, Rose-Marie Javier2, Helene Chifflot4, Jacques-Eric Gottenberg5 and Jean Sibilia6, 1Hautepierre Strasbourg university, Strasbourg, France, 2Hautepierre Strasbourg Hospital University, Strasbourg, France, 3Hopital Hautepierre, Strasbourg, France, 4Hautepierre Strasbourg Hospital University, 67000, France, 5Strasbourg University Hospital, Strasbourg, France, 6Service de rhumatologie, Hôpitaux Universitaires de Strasbourg, Strasbourg, France, Strasbourg, France

Less-Experienced Rheumatologists Can Improve Agreement in the Detection of Clinical Synovitis Through Consensus in Rheumatoid Arthritis (RA)
Peter Cheung1, Vincent Andre2, Natalie Balandraud3, Gerard H. Chales4, Isabelle Chary-Valckaneare5, Emmanuel Chatelus6, Emmanuelle Dernis2, Ghislaine Gill5, Melanie Gilson7, Sandrine Guis3, Thierry Marhadour8, Gael Mouterde9, Stephan Pavy10, Francois Pouyol11, Pascal Richette12, Adeline Ruyssen-Witrand13, Martin Soubrier14, Maxime Dougados15 and Laure Gossec16, 1Hospital Cochin, Paris, France, 2Centre Hospitalier, Le Mans, France, 3Hopital de la Conception, Marseilles, France, 4CHR - Hopital Sud, Rennes, France, 5Hopital de Brabois, Nancy, France, 6Hopital Hautepierre, Strasbourg, France, 7CH Grenoble Hopital Sud, Grenoble, France, 8CHU La Cavale Blanche, Brest, France, 9Hopital Lapeyronie, Montpellier, France, 10Hopital Bicetre, Paris, France, 11Hopital de Roger Salengro, Lille, France, 12Lariboisière Hospital, Paris, France, 13Hopitaux de Toulouse, Toulouse, France, 14CHU CLERMONT-FERRAND, Clermont-Ferrand, France, 15Paris-Descartes University, Cochin Hospital, Paris, France, 16Cochin Hospital, Paris, France
Hôpital Hautepierre
Mycophenolate Mofetil in Children with Lupus: Clinical Findings in Favour of Therapeutic Drug Monitoring
Brigitte Bader-Meunier1, Camille Jurado2, Bruno Ranchin3, Stéphane Decramer4, Michel Fischbach5, Etienne Berard6 and Franck Saint Marcoux2, 1Hôpital Necker, Paris, France, 2INSERM UMR –S850, Limoges, France, 3Hôpital Femme-Mère-Enfant, Lyon, France, 4hôpital Purpan, Toulouse, France, 5Hôpital Hautepierre, Strasbourg, France, 6Hôpital Lenval, Nice, France
Hôpital Henri Mondor
Some Clinical Features Are Associated with MODIC I Changes in Patient with Chronic Low Back pain ; Results of a Case Control Study
Florian Bailly1, Jean-Yves Maigne2, Stéphane Genevay3, Marc Marty4, Frédérique Gandjbakhch1, Sylvie Rozenberg5 and Violaine Foltz6, 1Hopital Pitié Salpétrière, Paris, France, 2Hôpital Hôtel Dieu, Paris, France, 3Hospital-Beau-Sejour, Geneva, Switzerland, 4Hôpital Henri Mondor, Créteil, France, 5Hopital La Pitie, Paris, France, 6Hôpital Pitié Salpétrière, Paris, France
Hopital Henri-Mondor
Biologics In Relapsing Polychondritis: a Literature Review
Fernando Kemta Lekpa1, Virginia Byers Kraus2 and Xavier Chevalier1, 1Hopital Henri-Mondor, Creteil, France, 2Duke University Medical Center, Durham, NC
Hôpital Hôtel Dieu
Some Clinical Features Are Associated with MODIC I Changes in Patient with Chronic Low Back pain ; Results of a Case Control Study
Florian Bailly1, Jean-Yves Maigne2, Stéphane Genevay3, Marc Marty4, Frédérique Gandjbakhch1, Sylvie Rozenberg5 and Violaine Foltz6, 1Hopital Pitié Salpétrière, Paris, France, 2Hôpital Hôtel Dieu, Paris, France, 3Hospital-Beau-Sejour, Geneva, Switzerland, 4Hôpital Henri Mondor, Créteil, France, 5Hopital La Pitie, Paris, France, 6Hôpital Pitié Salpétrière, Paris, France
Hopital Hotel Dieu
Distinct Rheumatological Features Induced by Aromatase Inhibitors in Breast Cancer Patients: A Prospective Multicenter Cohort Study of 138 Women with Breast Cancer
Serge Perrot1, Paul Cottu2, Xavier Decleves1, Laure Chauvenet1, Christophe Tournigand3, Jean-Yves Pierga2, Didier Bouhassira4 and Francoise Laroche3, 1Hopital Hotel Dieu, Paris, France, 2Curie Institute, Paris, France, 3Saint Antoine Hospital, Paris, France, 4Ambroise Paré Hospital, Boulogne, France

Differences in Patient Acceptable Symptomatic State (PASS) Thresholds and Minimal Clinically Important Improvement (MCII) for Pain At Rest and on Movement in Patients with Lower Limb Osteoarthritis
Serge Perrot, Hopital Hotel Dieu, Paris, France, Philippe Bertin, Chu Dupuytren, Limoges, France and Philippe Ravaud, Hopital Hotel Dieu, Paris Descartes University, Paris, France
Hopital Hotel Dieu, Paris Descartes University
Serum IL-21 Is Increased and Associated with Higher Disease Activity and Higher Serum Levels of Markers of B-Cell Activation in Primary Sjögren's Syndrome
Jacques-Eric Gottenberg1, Ghada Alsaleh1, Corinne Miceli-Richard2, Raphaèle Seror3, Joelle Benessiano4, Valerie Devauchelle-Pensec5, Philippe Dieude6, Jean Jacques Dubost7, Anne-Laure Fauchais8, Vincent Goeb9, Eric Hachulla10, Pierre yves Hatron11, C. Larroche12, Véronique Le Guern13, Jacques Morel14, Aleth Perdriger15, Xavier Puechal16, Stephanie Rist17, Alain Saraux18, Damien Sène19, Jean Sibilia20, Karine Inamo21, Philippe Ravaud22 and Xavier Mariette23, 1Strasbourg University Hospital, Strasbourg, France, 2Hopital Bicêtre, Le Kremlin Bicêtre, France, 3Bicetre university hospital, LE Kremlin-Bicetre, France, 4Rheumatology, Paris Unervisity Hospital BICHAT, France, 5Brest Occidentale university, Brest, France, 6APHP, Hopital Bichat, Paris, France, 7CHU Gabriel Montpied, Clermont-Ferrand, France, 8Hospital, Limoges, France, 9Rheumatology, Rouen Unervisity Hospital, France, France, 10Internal Medicine, Lille CEDEX, France, 11Service de médecine interne, Hôpital Claude Huriez, Université Lille II, Lille, France, Paris, France, 12Hospital University Bobigny, France, 13Cochin Hospital, Paris, France, 14Hopital Lapeyronie, Montpellier, France, 15Hôpital Sud, Rennes, France, 16Le Mans General Hospital, Le Mans, France, 17Hospital University Orléans, France, 18CHU de la Cavale Blanche, Brest Cedex, France, 19Pitie-Salpetriere Hospital, Paris, France, 20Service de rhumatologie, Hôpitaux Universitaires de Strasbourg, Strasbourg, France, Strasbourg, France, 21Nihon Univ Hikarigoaka Hosp, Nerima-ku Tokyo, Japan, 22Hopital Hotel Dieu, Paris Descartes University, Paris, France, 23Université Paris-Sud, Le Kremlin Bicetre, France

Characteristics and Impact of Pain in Systemic Sclerosis: Comparison with Rheumatoid Arthritis
Serge Perrot, Hopital Hotel Dieu, Paris Descartes University, Paris, France, Philippe Dieude, APHP, Hopital Bichat, Paris, France and Yannick Allanore, Paris Descartes University, Rheumatology A department, Cochin Hospital, Paris, France

Results of a Randomized Controlled Study of Adalimumab for Steroid Sparing in Patients with Giant-Cell Arteritis
Xavier Mariette, Université Paris-Sud, Le Kremlin Bicetre, France, Gabriel Baron, Epidemiology, Paris, France, Eric Hachulla, Internal Medicine, Lille CEDEX, France, Michel DeBandt, Abstract Medical Int'l, Boulogne, France, C. Larroche, Hospital University Bobigny, France, Xavier Puéchal, Le Mans General Hospital, Le Mans, France, Francois Maurier, Division of internal Medicine, CHR Metz, Metz, Metz, France, B. de Wazieres, CHU de Nimes, Nimes, France, T. Quemeneur, CHR de Valenciennes, Valenciennes, France and Philippe Ravaud, Hopital Hotel Dieu, Paris Descartes University, Paris, France

Differences in Patient Acceptable Symptomatic State (PASS) Thresholds and Minimal Clinically Important Improvement (MCII) for Pain At Rest and on Movement in Patients with Lower Limb Osteoarthritis
Serge Perrot, Hopital Hotel Dieu, Paris, France, Philippe Bertin, Chu Dupuytren, Limoges, France and Philippe Ravaud, Hopital Hotel Dieu, Paris Descartes University, Paris, France

Switching From Rituximab to Abatacept: Tolerance Data of 203 Patients Prospectively Followed up in the
Jacques-Eric Gottenberg, Strasbourg University Hospital, Strasbourg, France, Thierry Schaeverbeke, Pellegrin Hospital, Bordeaux, France, Philippe Gaudin, CHU Hôpital Sud, Grenoble Teaching Hospital, Echirolles, France, Liana E. Euller-Ziegler, L Archet Hospital (University), Nice CEDEX 3, France, Thao Pham, Sainte Marguerite Hospital, Marseille, France, Rene-Marc Flipo, Hopital R Salengro CHRU, Lille CEDEX, France, Alain G. Cantagrel, Hopital Purpan, Toulouse CEDEX 9, France, Eric Houvenagel, St Philibert Hospital, Lomme 59462, France, S. Redecker, Hospital University Abbeville, France, Xavier X. Le Loet, CHU de ROUEN, Rouen CEDEX, France, Pascal Claudepierre, Université Paris Est, Laboratoire d'Investigation Clinique (LIC) EA 4393, AP-HP, Hôpital Henri-Mondor, Rheumatology department, Creteil, France, Isabelle Pane, France, Philippe Ravaud, Hopital Hotel Dieu, Paris Descartes University, Paris, France and Xavier Mariette, Université Paris-Sud, Le Kremlin Bicetre, France
Hopital La Pitie
Surgery Versus Endovascular Repair in Takayasu Arteritis: A Multicenter Study of 166 Procedures
David Saadoun1, Marc Lambert2, Tristan Mirault3, Yoland Shoindre1, Zahir Amoura4, Mathieu Resche Rigon1, Pierre yves Hatron5, Joseph Emmerich3 and Patrice P. Cacoub6, 1Department of Internal Medicine and Laboratory I3 “Immunology, Immunopathology, Immunotherapy”, UMR CNRS 7211, INSERM U959, Groupe Hospitalier Pitié-Salpetrière, Université Pierre et Marie Curie, Paris 6, Paris, France, Paris, France, 2Service de médecine interne, Hôpital Claude Huriez, Université Lille II, Lille, France, Lille, France, 3Service de Médecine Vasculaire HEGP, Paris, France, 4CHU Pitié-Salpêtrière, Paris, France, 5Service de médecine interne, Hôpital Claude Huriez, Université Lille II, Lille, France, Paris, France, 6Hopital La Pitie, Paris, France

Some Clinical Features Are Associated with MODIC I Changes in Patient with Chronic Low Back pain ; Results of a Case Control Study
Florian Bailly1, Jean-Yves Maigne2, Stéphane Genevay3, Marc Marty4, Frédérique Gandjbakhch1, Sylvie Rozenberg5 and Violaine Foltz6, 1Hopital Pitié Salpétrière, Paris, France, 2Hôpital Hôtel Dieu, Paris, France, 3Hospital-Beau-Sejour, Geneva, Switzerland, 4Hôpital Henri Mondor, Créteil, France, 5Hopital La Pitie, Paris, France, 6Hôpital Pitié Salpétrière, Paris, France
Hopital Lapeyronie
Defining Rheumatoid Arthritis From Radiographic Erosive Abnormalities in the Light of the ACR/EULAR 2010 Criteria
Cédric Lukas, Montpellier 1 University, Lapeyronie Hospital, 371, Avenue du Doyen Gaston Giraud, 34295 Montpellier Cedex 5, France, Montpellier, France, R. Knevel, LUMC, Department of Rheumatology, Leiden, Netherlands, Annette H.M. van der Helm-van Mil, Leiden University Medical Center, Leiden, Netherlands, Nathalie Rincheval, Institut Universitaire de Recherche Clinique, Montpellier, France, Désirée van der Heijde, Department of Rheumatology, Leiden University Medical Center, Leiden, Netherlands and Bernard G. Combe, Hopital Lapeyronie, Montpellier, France

Identification of Patients Who Could Require Early Biologic Therapy by Developping a Matrix Predicting Rapid Radiographic Progression in Early Rheumatoid Arthritis Patients Treated by Methotrexate. A Study Based on the ESPOIR Cohort Data
Bruno Fautrel, Université Pierre et Marie Curie - Paris 6 - Pitie Salpetriere University Hospital, Paris, France, Benjamin Granger, Université Pierre et Marie Curie - Paris 6 ; AP-HP, Paris, France, Bernard G. Combe, Hopital Lapeyronie, Montpellier, France, Xavier X. Le Loet, CHU de ROUEN, Rouen CEDEX, France and ESPOIR Scientific Committee, Paris

Comparative Effectiveness of Rituximab and Abatacept in 1192 Patients with Rheumatoid Arthritis Included in the French Society of Rheumatology AIR and ORA Registries
Jacques-Eric Gottenberg, Strasbourg University Hospital, Strasbourg, France, Philippe Ravaud, Hotel Dieu University hospital, France, Thomas Bardin, Service de Rhumatologie. Centre Viggo Petersen. Hôpital Lariboisiere, Paris, France, Patrice Cacoub, CHU Pitié-Salpêtrière, Paris, France, Alain G. Cantagrel, Hopital Purpan, Toulouse CEDEX 9, France, Bernard G. Combe, Hopital Lapeyronie, Montpellier, France, Maxime Dougados, Paris-Descartes University, Cochin Hospital, Paris, France, Rene-Marc Flipo, Hopital R Salengro CHRU, Lille CEDEX, France, Bertrand Godeau, Service de médecine interne, Université Paris Est Créteil, AP-HP, Hôpital Mondor Créteil, France, Creteil, France, Loic Guillevin, Cochin University Hospital, Paris, France, Xavier X. Le Loet, CHU de ROUEN, Rouen CEDEX, France, Eric Hachulla, Internal Medicine, Lille CEDEX, France, Thierry Schaeverbeke, Pellegrin Hospital, Bordeaux, France, Jean Sibilia, Service de rhumatologie, Hôpitaux Universitaires de Strasbourg, Strasbourg, France, Strasbourg, France, Isabelle Pane, France, Gabriel Baron, Epidemiology, Paris, France and Xavier Mariette, Université Paris-Sud, Le Kremlin Bicetre, France

RISK of HERPES VIRUSES INFECTIONS (HSV,VZV) DURING ANTI-TNF THERAPY In PATIENTS with INFLAMMATORY RHEUMATIC DISEASES Systematic Review and Meta-Analysis
Hélène Che, Jacques Morel, Bernard G. Combe and Cédric Lukas, Hopital Lapeyronie, Montpellier, France

One Single Infusion of Rituximab 1g Might Be Sufficient in the Long-Term Management of Rheumatoid Arthritis Patients Responding to a First Cycle of Rituximab (2 x 1g): Results of a 2-Year Multi-Center Randomized Controlled Trial
Maxime Dougados, Paris-Descartes University, Cochin Hospital, Paris, France, Stephanie Rouanet, Roche, Neuilly sur Seine, France, Jean Sibilia, Service de rhumatologie, Hôpitaux Universitaires de Strasbourg, Strasbourg, France, Strasbourg, France, Bernard G. Combe, Hopital Lapeyronie, Montpellier, France, Xavier X. Le Loet, CHU de ROUEN, Rouen CEDEX, France, Jacques G. Tebib, Centre Hosp Lyon Sud, Pierre Benite, France, Rosemary Jourdan, Roche, Neuilly Sur Seine, France and Xavier Mariette, Université Paris-Sud, Le Kremlin Bicetre, France

Serum IL-21 Is Increased and Associated with Higher Disease Activity and Higher Serum Levels of Markers of B-Cell Activation in Primary Sjögren's Syndrome
Jacques-Eric Gottenberg1, Ghada Alsaleh1, Corinne Miceli-Richard2, Raphaèle Seror3, Joelle Benessiano4, Valerie Devauchelle-Pensec5, Philippe Dieude6, Jean Jacques Dubost7, Anne-Laure Fauchais8, Vincent Goeb9, Eric Hachulla10, Pierre yves Hatron11, C. Larroche12, Véronique Le Guern13, Jacques Morel14, Aleth Perdriger15, Xavier Puechal16, Stephanie Rist17, Alain Saraux18, Damien Sène19, Jean Sibilia20, Karine Inamo21, Philippe Ravaud22 and Xavier Mariette23, 1Strasbourg University Hospital, Strasbourg, France, 2Hopital Bicêtre, Le Kremlin Bicêtre, France, 3Bicetre university hospital, LE Kremlin-Bicetre, France, 4Rheumatology, Paris Unervisity Hospital BICHAT, France, 5Brest Occidentale university, Brest, France, 6APHP, Hopital Bichat, Paris, France, 7CHU Gabriel Montpied, Clermont-Ferrand, France, 8Hospital, Limoges, France, 9Rheumatology, Rouen Unervisity Hospital, France, France, 10Internal Medicine, Lille CEDEX, France, 11Service de médecine interne, Hôpital Claude Huriez, Université Lille II, Lille, France, Paris, France, 12Hospital University Bobigny, France, 13Cochin Hospital, Paris, France, 14Hopital Lapeyronie, Montpellier, France, 15Hôpital Sud, Rennes, France, 16Le Mans General Hospital, Le Mans, France, 17Hospital University Orléans, France, 18CHU de la Cavale Blanche, Brest Cedex, France, 19Pitie-Salpetriere Hospital, Paris, France, 20Service de rhumatologie, Hôpitaux Universitaires de Strasbourg, Strasbourg, France, Strasbourg, France, 21Nihon Univ Hikarigoaka Hosp, Nerima-ku Tokyo, Japan, 22Hopital Hotel Dieu, Paris Descartes University, Paris, France, 23Université Paris-Sud, Le Kremlin Bicetre, France

Fatigue in Patients with Rheumatoid Arthritis Treated with Tocilizumab (Actemra®) in Real Life: Clinically Relevant Improvement in 62% of Patients At 4 Months and Rapid Onset of Action. the PEPS Study
Laure Gossec, Cochin Hospital, Paris, France, Stephanie Rouanet, Roche, Neuilly sur Seine, France, Ghislaine Steinberg, Roche, Neuilly Sur Seine, France and Bernard G. Combe, Hopital Lapeyronie, Montpellier, France

Demonstration of the Symptomatic and Structural Effect of Methotrexate in Daily Practice As the First RA-DMARD Despite Its Sub-Optimal Use: Results From the ESPOIR Early Synovitis Cohort
Cécile Gaujoux-Viala, Paris 6 – Pierre et Marie Curie University; Rheumatology, Pitié-Salpêtrière Hospital, Paris, France, Simon Paternotte, Hopital Cochin, Paris, France, Bernard G. Combe, Hopital Lapeyronie, Montpellier, France and Maxime Dougados, Paris-Descartes University, Paris, France

Low Serum IgG Level After Rituximab Is Associated with An Increased Risk of Serious Infections in Rheumatoid Arthritis: Data of the AIR Registry
Jacques-Eric Gottenberg1, Philippe Ravaud2, Thomas Bardin3, Patrice Cacoub4, Alain G. Cantagrel5, Bernard G. Combe6, Maxime Dougados7, Rene-Marc Flipo8, Bertrand Godeau9, Loic Guillevin10, Xavier X. Le Loet11, Eric Hachulla12, Thierry Schaeverbeke13, Jean Sibilia14, Isabelle Pane15, Adelina Abbe15, Gabriel Baron16 and Xavier Mariette17, 1Strasbourg University Hospital, Strasbourg, France, 2Hotel Dieu University hospital, France, 3Service de Rhumatologie. Centre Viggo Petersen. Hôpital Lariboisiere, Paris, France, 4CHU Pitié-Salpêtrière, Paris, France, 5Hopital Purpan, Toulouse CEDEX 9, France, 6Hopital Lapeyronie, Montpellier, France, 7Paris-Descartes University, Cochin Hospital, Paris, France, 8Hopital R Salengro CHRU, Lille CEDEX, France, 9Service de médecine interne, Université Paris Est Créteil, AP-HP, Hôpital Mondor Créteil, France, Creteil, France, 10Cochin University Hospital, Paris, France, 11CHU de ROUEN, Rouen CEDEX, France, 12Internal Medicine, Lille CEDEX, France, 13Pellegrin Hospital, Bordeaux, France, 14Service de rhumatologie, Hôpitaux Universitaires de Strasbourg, Strasbourg, France, Strasbourg, France, 15France, 16Epidemiology, Paris, France, 17Université Paris-Sud, Le Kremlin Bicetre, France

Less-Experienced Rheumatologists Can Improve Agreement in the Detection of Clinical Synovitis Through Consensus in Rheumatoid Arthritis (RA)
Peter Cheung1, Vincent Andre2, Natalie Balandraud3, Gerard H. Chales4, Isabelle Chary-Valckaneare5, Emmanuel Chatelus6, Emmanuelle Dernis2, Ghislaine Gill5, Melanie Gilson7, Sandrine Guis3, Thierry Marhadour8, Gael Mouterde9, Stephan Pavy10, Francois Pouyol11, Pascal Richette12, Adeline Ruyssen-Witrand13, Martin Soubrier14, Maxime Dougados15 and Laure Gossec16, 1Hospital Cochin, Paris, France, 2Centre Hospitalier, Le Mans, France, 3Hopital de la Conception, Marseilles, France, 4CHR - Hopital Sud, Rennes, France, 5Hopital de Brabois, Nancy, France, 6Hopital Hautepierre, Strasbourg, France, 7CH Grenoble Hopital Sud, Grenoble, France, 8CHU La Cavale Blanche, Brest, France, 9Hopital Lapeyronie, Montpellier, France, 10Hopital Bicetre, Paris, France, 11Hopital de Roger Salengro, Lille, France, 12Lariboisière Hospital, Paris, France, 13Hopitaux de Toulouse, Toulouse, France, 14CHU CLERMONT-FERRAND, Clermont-Ferrand, France, 15Paris-Descartes University, Cochin Hospital, Paris, France, 16Cochin Hospital, Paris, France

First Year Radiological Erosive Progression Is a New Predictor of Further Erosive Progression in Early Arthritis: Results of the ESPOIR Cohort
Gabriel Tobon, Unit of immunology, Brest, France, Alain Saraux, Brest Occidentale University, Brest, France, Cédric Lukas, Montpellier 1 University, Lapeyronie Hospital, 371, Avenue du Doyen Gaston Giraud, 34295 Montpellier Cedex 5, France, Montpellier, France, Frédérique Gandjbakhch, Hopital Pitié Salpétrière, Paris, France, Xavier Mariette, Université Paris-Sud, Le Kremlin Bicetre, France, Bernard G. Combe, Hopital Lapeyronie, Montpellier, France and Valerie Devauchelle-Pensec, Brest Occidentale university, Brest, France

Defining Erosive DISEASE Typical of RA In the LIGHT of the 2010 ACR/EULAR Criteria for Rheumatoid Arthritis –PHASE 1.
R. Knevel1, Désirée van der Heijde1, Tom W.J. Huizinga1, Cédric Lukas2, Bernard G. Combe2 and Annette H.M. van der Helm-van Mil1, 1Leiden University Medical Center, Leiden, Netherlands, 2Hopital Lapeyronie, Montpellier, France

A Whole-Blood Transcriptomic Signature Predicts Clinical Response to Rituximab in Rheumatoid Arthritis
Jeremie Sellam1, Sandrine Marion-Thore2, F. Dumont2, Franck Letourneur3, Stephanie Rouanet4, Yassine Taoufik5, Jean Sibilia6, Jacques G. Tebib7, Xavier Le Loët8, Bernard G. Combe9, Maxime Dougados10, Xavier Mariette11 and Gilles Chiocchia3, 1Hopital Saint-Antoine, Pierre et Marie Curie University Paris 6, AP-HP, 75012, France, 2INSERM U1016, Institut Cochin, Paris Descartes University, Paris, France, 3Institut Cochin, 75014 Paris, France, 4Roche, Neuilly sur Seine, France, 5Hopital Bicetre, Université Paris Sud, AP-HP, France, 6Service de rhumatologie, Hôpitaux Universitaires de Strasbourg, Strasbourg, France, Strasbourg, France, 7Centre Hosp Lyon Sud, Pierre Benite, France, 8Department of Rheumatology, Rouen University Hospital & Inserm 905, Institute for Biomedical Research, University of Rouen, Rouen, France, 9Hopital Lapeyronie, Montpellier, France, 10Paris-Descartes University, Paris, France, 11Université Paris-Sud, Le Kremlin Bicetre, France

Etanercept Induces a Decrease in Left Ventricular Mass in Patients with Rheumatoid Arthritis
Claire Daien1, Pierre Fesler1, Vincent Daien2, Guilhem du Cailar1, Anne-Marie Dupuy1, Jean-Paul Cristol1, Jean Ribstein1, Bernard G. Combe1 and Jacques Morel1, 1Hopital Lapeyronie, Montpellier, France, 2Hopital Gui de Chauliac, Montpellier, France
Hôpital Lariboisière
Long-Term Efficacy and Safety of Canakinumab Versus Triamcinolone Acetonide in Acute Gouty Arthritis Patients
J.P. Brown1, A. So2, A. Dikranian3, R. Alten4, T. Bardin5, H. R. Schumacher6, A. Gimona7, G. Krammer7, A. Karpov7 and N. Schlesinger8, 1CHUQ-CHUL Research Centre, Laval University, Quebec City, QC, 2CHUV, Lausanne, Switzerland, 3San Diego Arthritis Medical Clinic, San Diego, CA, 4Charité Teaching Hospital–Schlosspark-Klinik, Berlin, Germany, 5Hôpital Lariboisière, Paris, France, 6University of Pennsylvania and VA Medical Center, Philadelphia, PA, 7Novartis Pharma AG, Basel, Switzerland, 8UMDNJ-Robert Wood Johnson Medical School, New Brunswick, NJ

Inflammation Suppression Over 24 Weeks in Patients with Gouty Arthritis: Results From Two Phase-III Core and Extension Studies Comparing Canakinumab with Triamcinolone Acetonide
A. So1, R. Alten2, H. R. Schumacher3, T. Bardin4, M. Bloch5, D. Richard6, A. Karpov6, T. Kiechle6 and N. Schlesinger7, 1CHUV, Lausanne, Switzerland, 2Charité Teaching Hospital–Schlosspark-Klinik, Berlin, Germany, 3University of Pennsylvania and VA Medical Center, Philadelphia, PA, 4Hôpital Lariboisière, Paris, France, 5Holdsworth House Medical Practice, Sydney, Australia, 6Novartis Pharma AG, Basel, Switzerland, 7UMDNJ-Robert Wood Johnson Medical School, New Brunswick, NJ

Effect of IL-1β Inhibition with Canakinumab Compared to Triamcinolone Acetonide on Pain Intensity and New Flares in Gouty Arthritis Patients with Chronic Kidney Disease Stage 2-5
P. Sunkureddi1, T. Bardin2, R. Alten3, N. Schlesinger4, M. Bloch5, T. Kiechle6, G. Krammer6, A. Shpilsky7 and A. So8, 1Clear Lake Rheumatology Center, Nassau Bay, TX, 2Hôpital Lariboisière, Paris, France, 3Charité Teaching Hospital–Schlosspark-Klinik, Berlin, Germany, 4UMDNJ-Robert Wood Johnson Medical School, New Brunswick, NJ, 5Holdsworth House Medical Practice, Sydney, Australia, 6Novartis Pharma AG, Basel, Switzerland, 7Novartis Pharmaceutical Corporation, East Hanover, NJ, 8CHUV, Lausanne, Switzerland

Comparison of Pain Intensity, Incidence of New Flares, Safety and Tolerability of Canakinumab Vs Triamcinolone Acetonide in Gouty Arthritis Patients with Cardiovascular Diseases or with Cardiovascular Risk Factors
N. Schlesinger, UMDNJ-Robert Wood Johnson Medical School, New Brunswick, NJ, J. P. Brown, CHUQ (CHUL) Research Centre, Laval University, Quebec City, QC, T. Bardin, Hôpital Lariboisière, Paris, France, T. Kiechle, Novartis Pharma AG, Basel, Switzerland, A. Shpilsky, Novartis Pharmaceutical Corporation, East Hanover, NJ, R. Alten, Charité Teaching Hospital–Schlosspark-Klinik, Berlin, Germany and A. So, CHUV, Lausanne, Switzerland

Efficacy of Canakinumab on Re-Treatment in Gouty Arthritis Patients with Limited Treatment Options: 24-Week Results From β-RELIEVED and β-RELIEVED-II Studies
R. Alten1, A. So2, Alan J. Kivitz3, T. Bardin4, M. Bloch5, A. Gimona6, A. Widmer6, G. Krammer6, N. Schlesinger7 and H. R. Schumacher8, 1Charité Teaching Hospital–Schlosspark-Klinik, Berlin, Germany, 2CHUV, Lausanne, Switzerland, 3Altoona Center for Clinical Research, Duncansville, PA, 4Hôpital Lariboisière, Paris, France, 5Holdsworth House Medical Practice, Sydney, Australia, 6Novartis Pharma AG, Basel, Switzerland, 7UMDNJ-Robert Wood Johnson Medical School, New Brunswick, NJ, 8University of Pennsylvania and VA Medical Center, Philadelphia, PA
Hôpital Lenval
Mycophenolate Mofetil in Children with Lupus: Clinical Findings in Favour of Therapeutic Drug Monitoring
Brigitte Bader-Meunier1, Camille Jurado2, Bruno Ranchin3, Stéphane Decramer4, Michel Fischbach5, Etienne Berard6 and Franck Saint Marcoux2, 1Hôpital Necker, Paris, France, 2INSERM UMR –S850, Limoges, France, 3Hôpital Femme-Mère-Enfant, Lyon, France, 4hôpital Purpan, Toulouse, France, 5Hôpital Hautepierre, Strasbourg, France, 6Hôpital Lenval, Nice, France
Hôpital Necker
Emperipolesis and Cell Death in NOD2-Related Blau Syndrome and Crohn's Disease   
Carl EI Janssen1, Carlos D. Rose2, A. Naranjo3, Brigitte Bader-Meunier4, Rolando Cimaz5, Miroslav Harjacek6, Pierre Quartier7, Rebecca Ten Cate8, Caroline Thomée9, Isabelle Cleynen1, Tammy M. Martin10, Gert De Hertogh1, Tania Roskams1, Valeer J. Desmet1 and Carine H. Wouters11, 1University Hospital Leuven, Leuven, Belgium, 2duPont Hospital for Children, Wilmington, DE, 3Hospital de G C Dr Negrin, Las Palmas GC, Spain, 4Hôpital Necker, Paris, France, 5Anna Meyer Children's Hospital, Florence, Italy, 6Zagreb, 7IRCCS G. Gaslini, Pediatria II, PRINTO, Paediatric Rheumatology, Genova, Italy, 8PO Box 9600, Leiden, Netherlands, 9Centre Hospitalier, Luxembourg, Luxembourg, 10Oregon Health & Science Univ, Portland, OR, 11Paediatric Rheumatology Internationsl Trials Organization, Leuven, Belgium

Mycophenolate Mofetil in Children with Lupus: Clinical Findings in Favour of Therapeutic Drug Monitoring
Brigitte Bader-Meunier1, Camille Jurado2, Bruno Ranchin3, Stéphane Decramer4, Michel Fischbach5, Etienne Berard6 and Franck Saint Marcoux2, 1Hôpital Necker, Paris, France, 2INSERM UMR –S850, Limoges, France, 3Hôpital Femme-Mère-Enfant, Lyon, France, 4hôpital Purpan, Toulouse, France, 5Hôpital Hautepierre, Strasbourg, France, 6Hôpital Lenval, Nice, France
Hôpital Necker-Enfants Malades
Creation of A COHORT of French PATIENTS with CHRONIC RECURRENT Multifocal OSTEITIS : PRELIMINARY RESULTS
Julien Wipff1, M.-A. Dumitrescu2, Mathie Lorrot3, Albert Faye2, S. lacassagne-Compeyrot4, B. Bader Meunier4, R. Mouy4, Carine H. Wouters5, Marine Desjonqueres6, S. Jean7, V. Despert7, A. Duquesne6, I. Lemelle8, P. Pillet9, M. Grall-Lerosey10, Pierre Quartier11 and Chantal Job-Deslandre12, 1Paris descartes Universityn Rheumatology A, Cochin Hospital, Paris, France, 2Paris, France, 3Paediatry, Robert Debré hospital, Paris, France, 4University Paris Descartes, Paediatry, Necker hospital, Paris, France, 5Paediatric Rheumatology Internationsl Trials Organization, Leuven, Belgium, 6Hopital Femme Mere Enfant, Groupement Hospitalier Est, Lyon, France, 7Paediatry, CHU, Rennes, France, 8Paediatry, CHU, Nancy, France, 9Paediatry, CHU, Bordeaux, France, 10Paediatry, CHU, Rouen, France, 11Hôpital Necker-Enfants Malades, Paris, France, 12Hopital Cochin, Paris Cedex 14, France
Hôpital Pitié Salpétrière
Some Clinical Features Are Associated with MODIC I Changes in Patient with Chronic Low Back pain ; Results of a Case Control Study
Florian Bailly1, Jean-Yves Maigne2, Stéphane Genevay3, Marc Marty4, Frédérique Gandjbakhch1, Sylvie Rozenberg5 and Violaine Foltz6, 1Hopital Pitié Salpétrière, Paris, France, 2Hôpital Hôtel Dieu, Paris, France, 3Hospital-Beau-Sejour, Geneva, Switzerland, 4Hôpital Henri Mondor, Créteil, France, 5Hopital La Pitie, Paris, France, 6Hôpital Pitié Salpétrière, Paris, France
Hopital Pitié Salpétrière
Some Clinical Features Are Associated with MODIC I Changes in Patient with Chronic Low Back pain ; Results of a Case Control Study
Florian Bailly1, Jean-Yves Maigne2, Stéphane Genevay3, Marc Marty4, Frédérique Gandjbakhch1, Sylvie Rozenberg5 and Violaine Foltz6, 1Hopital Pitié Salpétrière, Paris, France, 2Hôpital Hôtel Dieu, Paris, France, 3Hospital-Beau-Sejour, Geneva, Switzerland, 4Hôpital Henri Mondor, Créteil, France, 5Hopital La Pitie, Paris, France, 6Hôpital Pitié Salpétrière, Paris, France

First Year Radiological Erosive Progression Is a New Predictor of Further Erosive Progression in Early Arthritis: Results of the ESPOIR Cohort
Gabriel Tobon, Unit of immunology, Brest, France, Alain Saraux, Brest Occidentale University, Brest, France, Cédric Lukas, Montpellier 1 University, Lapeyronie Hospital, 371, Avenue du Doyen Gaston Giraud, 34295 Montpellier Cedex 5, France, Montpellier, France, Frédérique Gandjbakhch, Hopital Pitié Salpétrière, Paris, France, Xavier Mariette, Université Paris-Sud, Le Kremlin Bicetre, France, Bernard G. Combe, Hopital Lapeyronie, Montpellier, France and Valerie Devauchelle-Pensec, Brest Occidentale university, Brest, France
Hopital Purpan
Comparative Effectiveness of Rituximab and Abatacept in 1192 Patients with Rheumatoid Arthritis Included in the French Society of Rheumatology AIR and ORA Registries
Jacques-Eric Gottenberg, Strasbourg University Hospital, Strasbourg, France, Philippe Ravaud, Hotel Dieu University hospital, France, Thomas Bardin, Service de Rhumatologie. Centre Viggo Petersen. Hôpital Lariboisiere, Paris, France, Patrice Cacoub, CHU Pitié-Salpêtrière, Paris, France, Alain G. Cantagrel, Hopital Purpan, Toulouse CEDEX 9, France, Bernard G. Combe, Hopital Lapeyronie, Montpellier, France, Maxime Dougados, Paris-Descartes University, Cochin Hospital, Paris, France, Rene-Marc Flipo, Hopital R Salengro CHRU, Lille CEDEX, France, Bertrand Godeau, Service de médecine interne, Université Paris Est Créteil, AP-HP, Hôpital Mondor Créteil, France, Creteil, France, Loic Guillevin, Cochin University Hospital, Paris, France, Xavier X. Le Loet, CHU de ROUEN, Rouen CEDEX, France, Eric Hachulla, Internal Medicine, Lille CEDEX, France, Thierry Schaeverbeke, Pellegrin Hospital, Bordeaux, France, Jean Sibilia, Service de rhumatologie, Hôpitaux Universitaires de Strasbourg, Strasbourg, France, Strasbourg, France, Isabelle Pane, France, Gabriel Baron, Epidemiology, Paris, France and Xavier Mariette, Université Paris-Sud, Le Kremlin Bicetre, France

Low Serum IgG Level After Rituximab Is Associated with An Increased Risk of Serious Infections in Rheumatoid Arthritis: Data of the AIR Registry
Jacques-Eric Gottenberg1, Philippe Ravaud2, Thomas Bardin3, Patrice Cacoub4, Alain G. Cantagrel5, Bernard G. Combe6, Maxime Dougados7, Rene-Marc Flipo8, Bertrand Godeau9, Loic Guillevin10, Xavier X. Le Loet11, Eric Hachulla12, Thierry Schaeverbeke13, Jean Sibilia14, Isabelle Pane15, Adelina Abbe15, Gabriel Baron16 and Xavier Mariette17, 1Strasbourg University Hospital, Strasbourg, France, 2Hotel Dieu University hospital, France, 3Service de Rhumatologie. Centre Viggo Petersen. Hôpital Lariboisiere, Paris, France, 4CHU Pitié-Salpêtrière, Paris, France, 5Hopital Purpan, Toulouse CEDEX 9, France, 6Hopital Lapeyronie, Montpellier, France, 7Paris-Descartes University, Cochin Hospital, Paris, France, 8Hopital R Salengro CHRU, Lille CEDEX, France, 9Service de médecine interne, Université Paris Est Créteil, AP-HP, Hôpital Mondor Créteil, France, Creteil, France, 10Cochin University Hospital, Paris, France, 11CHU de ROUEN, Rouen CEDEX, France, 12Internal Medicine, Lille CEDEX, France, 13Pellegrin Hospital, Bordeaux, France, 14Service de rhumatologie, Hôpitaux Universitaires de Strasbourg, Strasbourg, France, Strasbourg, France, 15France, 16Epidemiology, Paris, France, 17Université Paris-Sud, Le Kremlin Bicetre, France

Switching From Rituximab to Abatacept: Tolerance Data of 203 Patients Prospectively Followed up in the
Jacques-Eric Gottenberg, Strasbourg University Hospital, Strasbourg, France, Thierry Schaeverbeke, Pellegrin Hospital, Bordeaux, France, Philippe Gaudin, CHU Hôpital Sud, Grenoble Teaching Hospital, Echirolles, France, Liana E. Euller-Ziegler, L Archet Hospital (University), Nice CEDEX 3, France, Thao Pham, Sainte Marguerite Hospital, Marseille, France, Rene-Marc Flipo, Hopital R Salengro CHRU, Lille CEDEX, France, Alain G. Cantagrel, Hopital Purpan, Toulouse CEDEX 9, France, Eric Houvenagel, St Philibert Hospital, Lomme 59462, France, S. Redecker, Hospital University Abbeville, France, Xavier X. Le Loet, CHU de ROUEN, Rouen CEDEX, France, Pascal Claudepierre, Université Paris Est, Laboratoire d'Investigation Clinique (LIC) EA 4393, AP-HP, Hôpital Henri-Mondor, Rheumatology department, Creteil, France, Isabelle Pane, France, Philippe Ravaud, Hopital Hotel Dieu, Paris Descartes University, Paris, France and Xavier Mariette, Université Paris-Sud, Le Kremlin Bicetre, France
hôpital Purpan
Mycophenolate Mofetil in Children with Lupus: Clinical Findings in Favour of Therapeutic Drug Monitoring
Brigitte Bader-Meunier1, Camille Jurado2, Bruno Ranchin3, Stéphane Decramer4, Michel Fischbach5, Etienne Berard6 and Franck Saint Marcoux2, 1Hôpital Necker, Paris, France, 2INSERM UMR –S850, Limoges, France, 3Hôpital Femme-Mère-Enfant, Lyon, France, 4hôpital Purpan, Toulouse, France, 5Hôpital Hautepierre, Strasbourg, France, 6Hôpital Lenval, Nice, France
Hopital R Salengro CHRU
Comparative Effectiveness of Rituximab and Abatacept in 1192 Patients with Rheumatoid Arthritis Included in the French Society of Rheumatology AIR and ORA Registries
Jacques-Eric Gottenberg, Strasbourg University Hospital, Strasbourg, France, Philippe Ravaud, Hotel Dieu University hospital, France, Thomas Bardin, Service de Rhumatologie. Centre Viggo Petersen. Hôpital Lariboisiere, Paris, France, Patrice Cacoub, CHU Pitié-Salpêtrière, Paris, France, Alain G. Cantagrel, Hopital Purpan, Toulouse CEDEX 9, France, Bernard G. Combe, Hopital Lapeyronie, Montpellier, France, Maxime Dougados, Paris-Descartes University, Cochin Hospital, Paris, France, Rene-Marc Flipo, Hopital R Salengro CHRU, Lille CEDEX, France, Bertrand Godeau, Service de médecine interne, Université Paris Est Créteil, AP-HP, Hôpital Mondor Créteil, France, Creteil, France, Loic Guillevin, Cochin University Hospital, Paris, France, Xavier X. Le Loet, CHU de ROUEN, Rouen CEDEX, France, Eric Hachulla, Internal Medicine, Lille CEDEX, France, Thierry Schaeverbeke, Pellegrin Hospital, Bordeaux, France, Jean Sibilia, Service de rhumatologie, Hôpitaux Universitaires de Strasbourg, Strasbourg, France, Strasbourg, France, Isabelle Pane, France, Gabriel Baron, Epidemiology, Paris, France and Xavier Mariette, Université Paris-Sud, Le Kremlin Bicetre, France

Low Serum IgG Level After Rituximab Is Associated with An Increased Risk of Serious Infections in Rheumatoid Arthritis: Data of the AIR Registry
Jacques-Eric Gottenberg1, Philippe Ravaud2, Thomas Bardin3, Patrice Cacoub4, Alain G. Cantagrel5, Bernard G. Combe6, Maxime Dougados7, Rene-Marc Flipo8, Bertrand Godeau9, Loic Guillevin10, Xavier X. Le Loet11, Eric Hachulla12, Thierry Schaeverbeke13, Jean Sibilia14, Isabelle Pane15, Adelina Abbe15, Gabriel Baron16 and Xavier Mariette17, 1Strasbourg University Hospital, Strasbourg, France, 2Hotel Dieu University hospital, France, 3Service de Rhumatologie. Centre Viggo Petersen. Hôpital Lariboisiere, Paris, France, 4CHU Pitié-Salpêtrière, Paris, France, 5Hopital Purpan, Toulouse CEDEX 9, France, 6Hopital Lapeyronie, Montpellier, France, 7Paris-Descartes University, Cochin Hospital, Paris, France, 8Hopital R Salengro CHRU, Lille CEDEX, France, 9Service de médecine interne, Université Paris Est Créteil, AP-HP, Hôpital Mondor Créteil, France, Creteil, France, 10Cochin University Hospital, Paris, France, 11CHU de ROUEN, Rouen CEDEX, France, 12Internal Medicine, Lille CEDEX, France, 13Pellegrin Hospital, Bordeaux, France, 14Service de rhumatologie, Hôpitaux Universitaires de Strasbourg, Strasbourg, France, Strasbourg, France, 15France, 16Epidemiology, Paris, France, 17Université Paris-Sud, Le Kremlin Bicetre, France

Switching From Rituximab to Abatacept: Tolerance Data of 203 Patients Prospectively Followed up in the
Jacques-Eric Gottenberg, Strasbourg University Hospital, Strasbourg, France, Thierry Schaeverbeke, Pellegrin Hospital, Bordeaux, France, Philippe Gaudin, CHU Hôpital Sud, Grenoble Teaching Hospital, Echirolles, France, Liana E. Euller-Ziegler, L Archet Hospital (University), Nice CEDEX 3, France, Thao Pham, Sainte Marguerite Hospital, Marseille, France, Rene-Marc Flipo, Hopital R Salengro CHRU, Lille CEDEX, France, Alain G. Cantagrel, Hopital Purpan, Toulouse CEDEX 9, France, Eric Houvenagel, St Philibert Hospital, Lomme 59462, France, S. Redecker, Hospital University Abbeville, France, Xavier X. Le Loet, CHU de ROUEN, Rouen CEDEX, France, Pascal Claudepierre, Université Paris Est, Laboratoire d'Investigation Clinique (LIC) EA 4393, AP-HP, Hôpital Henri-Mondor, Rheumatology department, Creteil, France, Isabelle Pane, France, Philippe Ravaud, Hopital Hotel Dieu, Paris Descartes University, Paris, France and Xavier Mariette, Université Paris-Sud, Le Kremlin Bicetre, France
Hôpital Saint Eloi
RNAi Mediated Silencing of the Autoantigen hnRNP-A2 Dcreases Inflammatory Arthritis by Inhibiting Activation of Cells of the Mononuclear Phagocytic System
Sonja Herman1, Jessy Presumey2, Juergen Pfatschbacher1, Wim B. Vandenberg3, Florence Apparailley2 and Gunter Steiner1, 1Medical University of Vienna, Vienna, Austria, 2Hôpital Saint Eloi, Montpellier, France, 3Radboud University Nijmegen Med Center, Nijmegen, Netherlands
Hopital Saint-Antoine, Pierre et Marie Curie University Paris 6, AP-HP
A Whole-Blood Transcriptomic Signature Predicts Clinical Response to Rituximab in Rheumatoid Arthritis
Jeremie Sellam1, Sandrine Marion-Thore2, F. Dumont2, Franck Letourneur3, Stephanie Rouanet4, Yassine Taoufik5, Jean Sibilia6, Jacques G. Tebib7, Xavier Le Loët8, Bernard G. Combe9, Maxime Dougados10, Xavier Mariette11 and Gilles Chiocchia3, 1Hopital Saint-Antoine, Pierre et Marie Curie University Paris 6, AP-HP, 75012, France, 2INSERM U1016, Institut Cochin, Paris Descartes University, Paris, France, 3Institut Cochin, 75014 Paris, France, 4Roche, Neuilly sur Seine, France, 5Hopital Bicetre, Université Paris Sud, AP-HP, France, 6Service de rhumatologie, Hôpitaux Universitaires de Strasbourg, Strasbourg, France, Strasbourg, France, 7Centre Hosp Lyon Sud, Pierre Benite, France, 8Department of Rheumatology, Rouen University Hospital & Inserm 905, Institute for Biomedical Research, University of Rouen, Rouen, France, 9Hopital Lapeyronie, Montpellier, France, 10Paris-Descartes University, Paris, France, 11Université Paris-Sud, Le Kremlin Bicetre, France
Hôpital Sud
Serum IL-21 Is Increased and Associated with Higher Disease Activity and Higher Serum Levels of Markers of B-Cell Activation in Primary Sjögren's Syndrome
Jacques-Eric Gottenberg1, Ghada Alsaleh1, Corinne Miceli-Richard2, Raphaèle Seror3, Joelle Benessiano4, Valerie Devauchelle-Pensec5, Philippe Dieude6, Jean Jacques Dubost7, Anne-Laure Fauchais8, Vincent Goeb9, Eric Hachulla10, Pierre yves Hatron11, C. Larroche12, Véronique Le Guern13, Jacques Morel14, Aleth Perdriger15, Xavier Puechal16, Stephanie Rist17, Alain Saraux18, Damien Sène19, Jean Sibilia20, Karine Inamo21, Philippe Ravaud22 and Xavier Mariette23, 1Strasbourg University Hospital, Strasbourg, France, 2Hopital Bicêtre, Le Kremlin Bicêtre, France, 3Bicetre university hospital, LE Kremlin-Bicetre, France, 4Rheumatology, Paris Unervisity Hospital BICHAT, France, 5Brest Occidentale university, Brest, France, 6APHP, Hopital Bichat, Paris, France, 7CHU Gabriel Montpied, Clermont-Ferrand, France, 8Hospital, Limoges, France, 9Rheumatology, Rouen Unervisity Hospital, France, France, 10Internal Medicine, Lille CEDEX, France, 11Service de médecine interne, Hôpital Claude Huriez, Université Lille II, Lille, France, Paris, France, 12Hospital University Bobigny, France, 13Cochin Hospital, Paris, France, 14Hopital Lapeyronie, Montpellier, France, 15Hôpital Sud, Rennes, France, 16Le Mans General Hospital, Le Mans, France, 17Hospital University Orléans, France, 18CHU de la Cavale Blanche, Brest Cedex, France, 19Pitie-Salpetriere Hospital, Paris, France, 20Service de rhumatologie, Hôpitaux Universitaires de Strasbourg, Strasbourg, France, Strasbourg, France, 21Nihon Univ Hikarigoaka Hosp, Nerima-ku Tokyo, Japan, 22Hopital Hotel Dieu, Paris Descartes University, Paris, France, 23Université Paris-Sud, Le Kremlin Bicetre, France
Hôpital Universitaire Cantonal de Genève
Churg–Strauss Syndrome: Analysis of 58 patients’ Relapses and Outcomes
Maxime Samson, Hôpital Cochin, University Paris Descartes, Paris, France, Camillo Ribi, Hôpital Universitaire Cantonal de Genève, Geneve, Switzerland, Pascal Cohen, Service de médecine interne, Centre de Références des Vascularites, Université Paris Descartes, APHP, Hôpital Cochin, 75005 Paris, France., Paris, France, Marc Stern, Hôpital Foch, Suresnes, France, Christian Pagnoux, University of Toronto, Toronto, ON, Jean-Francois Cordier, Division of Pneumology, Hôpital Louis-Pradel, Hospices Civils de Lyon, Lyon 1, Lyon, France, Luc Mouthon, Hopital Cochim, Paris, France and Loic Guillevin, Cochin University Hospital, Paris, France
Hopitaux de Toulouse
Less-Experienced Rheumatologists Can Improve Agreement in the Detection of Clinical Synovitis Through Consensus in Rheumatoid Arthritis (RA)
Peter Cheung1, Vincent Andre2, Natalie Balandraud3, Gerard H. Chales4, Isabelle Chary-Valckaneare5, Emmanuel Chatelus6, Emmanuelle Dernis2, Ghislaine Gill5, Melanie Gilson7, Sandrine Guis3, Thierry Marhadour8, Gael Mouterde9, Stephan Pavy10, Francois Pouyol11, Pascal Richette12, Adeline Ruyssen-Witrand13, Martin Soubrier14, Maxime Dougados15 and Laure Gossec16, 1Hospital Cochin, Paris, France, 2Centre Hospitalier, Le Mans, France, 3Hopital de la Conception, Marseilles, France, 4CHR - Hopital Sud, Rennes, France, 5Hopital de Brabois, Nancy, France, 6Hopital Hautepierre, Strasbourg, France, 7CH Grenoble Hopital Sud, Grenoble, France, 8CHU La Cavale Blanche, Brest, France, 9Hopital Lapeyronie, Montpellier, France, 10Hopital Bicetre, Paris, France, 11Hopital de Roger Salengro, Lille, France, 12Lariboisière Hospital, Paris, France, 13Hopitaux de Toulouse, Toulouse, France, 14CHU CLERMONT-FERRAND, Clermont-Ferrand, France, 15Paris-Descartes University, Cochin Hospital, Paris, France, 16Cochin Hospital, Paris, France

Does Clinical Assessment of Swollen and Tender Joints Reflect Inflammatory Synovitis in Rheumatoid Arthritis? A Comparative Study of Physician, Nurse and Patient Clinical Assessments Versus Ultrasonography (US) As the Gold Standard
Peter Cheung1, Laure Gossec2, Adeline Ruyssen-Witrand3, Catherine Le Bourlout4, Maryse Mezieres4 and Maxime Dougados5, 1National University Hospital, Singapore, Singapore, 2Cochin Hospital, Paris, France, 3Hopitaux de Toulouse, Toulouse, France, 4Hospital Cochin, Paris, France, 5Paris-Descartes University, Cochin Hospital, Paris, France
Hôpitaux Universitaires de Strasbourg
Carabin, a Negative Regulator of B Cells, Points Out a New Defective Biological Pathway In Systemic Lupus Erythematosus
Jean-Nicolas Schickel1, Jean-Louis Pasquali1, Anne Soley1, Anne-Marie Knapp1, Marion Decossas1, Luc Marcellin2, Anne-Sophie Korganow1, Thierry Martin1 and Pauline Soulas-Sprauel1, 1IBMC, Strasbourg, France, 2Hôpitaux Universitaires de Strasbourg, Strasbourg, France
Horizon Pharma GmbH
Integrated Safety Summary of Modified-Release Prednisone and Immediate-Release Prednisone Comparing Doses ≤5mg/Day Versus >5mg/Day
Frank Buttgereit1, Jacek Szechinski2, Gisela Doering3, Stephan Witte4, Christine Knauer4, Amy Y. Grahn5, Kenneth G. Saag6 and Rieke Alten7, 1Charité University Medicine, Berlin, Germany, 2Wroclaw Medical University, Wroclaw, Poland, 3Merck KgaA, Darmstadt, Germany, 4Horizon Pharma GmbH, Mannheim, Germany, 5Horizon Pharma, Inc., Northbrook, IL, 6University of Alabama at Birmingham, Birmingham, AL, 7Rheumatology Schlossparkklinik, Berlin, Germany
Horizon Pharma, Inc.
Integrated Safety Summary of Modified-Release Prednisone and Immediate-Release Prednisone Comparing Doses ≤5mg/Day Versus >5mg/Day
Frank Buttgereit1, Jacek Szechinski2, Gisela Doering3, Stephan Witte4, Christine Knauer4, Amy Y. Grahn5, Kenneth G. Saag6 and Rieke Alten7, 1Charité University Medicine, Berlin, Germany, 2Wroclaw Medical University, Wroclaw, Poland, 3Merck KgaA, Darmstadt, Germany, 4Horizon Pharma GmbH, Mannheim, Germany, 5Horizon Pharma, Inc., Northbrook, IL, 6University of Alabama at Birmingham, Birmingham, AL, 7Rheumatology Schlossparkklinik, Berlin, Germany
Hoshigaoka Koseinenkin Hospital
Celecoxib, a Selective Cyclooxygenase-2 Inhibitor, Improves a Bone Resorption Marker in Postmenopausal Women with Rheumatoid Arthritis
Shigeyoshi Tsuji1, Tetsuya Tomita2, Takao Iwai1, Takanobu Nakase1, Masayuki Hamada1, Hideo Kawai1 and Hideki Yoshikawa2, 1Hoshigaoka Koseinenkin Hospital, Hirakata city, Japan, 2Osaka University Graduate School of Medicine, Suita Osaka, Japan
Hosp for Special Surgery
Influenza Vaccine Intervention in a Rheumatology Clinic Population
Sherece Black1, Sarabjit Brar1, Lee Chang, Sylvia Chico1, Donald Makowski1, Virginia Haiduc1, Steven K. Magid3, Julie A. Pollino-Tanner1, Julita C. Reyes-Canu1, Ann M. Rakowicz1 and Monica C. Richey1, 1Hospital for Special Surgery, New York, NY, 2Hosp for Special Surgery, New York, NY

Ethical Issues in Rheumatology: A Survey of the American College of Rheumatology Membership
C. Ronald MacKenzie, Hosp for Special Surgery, New York, NY, Michele Meltzer, Jefferson Universtiy, Philadelphia, PA and Elizabeth A. Kitsis, Albert Einstein College of Med, Bronx, NY
Hosp Santa Maria
Seropositivity and Response to RTX: Data From the CERERRA Collaboration
Katerina Chatzidionysiou1, Elisabeth Lie2, Evgeny L. Nasonov3, Galina Lukina3, Merete L. Hetland4, Ulrik Tarp5, Ioan Ancuta6, Karel Pavelka7, Dan C. Nordström8, Cem Gabay9, Helena Canhao10, Matija Tomsic11, Piet LCM Van Riel12, Juan J. Gomez-Reino13, Tore K. Kvien2 and Ronald F. van Vollenhoven1, 1Karolinska Institute, Stockholm, Sweden, 2Diakonhjemmet Hospital, Oslo, Norway, 3ARBITER, Institute of Rheumatology, Moscow, Russia, 4DANBIO, Copenhagen University Hospital at Glostrup, Copenhagen, Denmark, 5Aarhus University Hospital, Aarhus, Denmark, 6Cantacuzino Hospital, Bucharest, Romania, 71Institute of Rheumatology, Department of Experimental Rheumatology, 1st Faculty of Medicine, Charles University in Prague, Prague, Czech Republic, 8ROB-FIN, Helsinki University Central Hospital, Helsinki, Finland, 9for the SCQM registry, University Hospitals of Geneva, Geneva, Switzerland, 10Hosp Santa Maria, Lisbon, Portugal, 11University Medical Centre Ljubjana, Ljubljana, Slovenia, 12Radboud University Nijmegen Medical Centre, Nijmegen, Netherlands, 13Hospital Clinico Universitario, Santiago, Spain
Hosp. Provincial
Early Rheumatoid Arthritis in Latin America. Low Socioeconomic Status Relates to High Disease Activity At Baseline
Loreto Massardo, Catholic University of Chile, Santiago 114-D, Chile, Bernardo A. Pons-Estel, Hospital Provincial, Rosario, Argentina, Mario H. Cardiel, Hospital General "Dr. Miguel Silva", Morelia, Mexico, Claudio Galarza-Maldonado, Hospital Monte Sinai , BIOMAB IPS, Cuenca, Ecuador, Mónica P. Sacnun, Hosp. Provincial, Rosario, Argentina, Enrique R. Soriano, Hospital Italiano de Buenos Aires, Buenos Aires, Argentina, Ieda Laurindo, Universidade de São Paulo, Sao Paulo, Brazil, Eduardo M. Acevedo-Vásquez, Hospital Nacional “Guillermo Almenara Irigoyen”, Lima, Peru, Carlo V. Caballero-Uribe, Continential Med Ctr, Barranquilla, Colombia, Oslando Padilla, Pontificia Universidad Catolica de Chile, Santiago, Chile, Marlene Guibert-Toledano, Centro de Investigaciones Médico Quirúrgicas, Habana, Ciudad Habana, Cuba, Rubén A. Montufar Guardado, Instituto Salvadoreño del Seguro Social, San Salvador, El Salvador, Sergio H. Jacobelli, Universidad Catolica de Chile, Santiago, Chile and Daniel E. Furst, UCLA Medical School, Los Angeles, CA
Hospitais da Universidade de Coimbra
Performance of the Ankylosing Spondylitis Disease Activity Score (ASDAS) in Patients Under Biological Therapies in Daily Practice – Results From the Portuguese Register Reuma.Pt
Sofia Ramiro1, Pedro Machado2, Raquel Roque3, Helena Santos4, Joaquim Polido-Pereira5, Daniela Peixoto6, Cátia Duarte7, Fernando Pimentel-Santos8, Cândida Silva4, J. E. Fonseca5, Filipa Teixeira6, Andrea Marques7, Filipe Araújo8, Jaime C. Branco8, José Pereira Da-Silva7, José Costa6, Jose A. Pereira Da Silva9, Luis Cunha Miranda4, J. Canas da Silva3, Helena Canhão5, A.M. Van Tubergen10, Desirée van der Heijde11, Robert Landewé12 and MJ Santos3, 1Hospital Garcia de Orta, Almada, Portugal and Academic Medical Center, University of Amsterdam, Amsterdam, Netherlands, 2Hospitais da Universidade de Coimbra, Coimbra, Portugal and Leiden University Medical Center, Leiden, Netherlands, 3Hospital Garcia de Orta, Almada, Portugal, 4Instituto Português de Reumatologia, Lisboa, Portugal, 5Instituto de Medicina Molecular, Faculdade de Medicina da Universidade de Lisboa and Rheumatology Department, Centro Hospitalar de Lisboa Norte, EPE, Hospital de Santa Maria, Lisboa, Portugal, 6Centro Hospitalar do Alto Minho, Hospital de Ponte de Lima, Ponte de Lima, Portugal, 7Hospitais da Universidade de Coimbra, Coimbra, Portugal, 8Centro Hospitalar de Lisboa Ocidental, Hospital Egas Moniz, Lisboa, Portugal, 9Centro Hospitalar de Lisboa Norte, Hospital de Santa Maria, Lisboa, Portugal, 10Maastricht University Medical Center, Maastricht, Netherlands, 11Leiden University Medical Center, Leiden, Netherlands, 12Academic Medical Center, University of Amsterdam, Amsterdam, Netherlands
Hospitais da Universidade de Coimbra, Coimbra, Portugal and Leiden University Medical Center
Performance of the Ankylosing Spondylitis Disease Activity Score (ASDAS) in Patients Under Biological Therapies in Daily Practice – Results From the Portuguese Register Reuma.Pt
Sofia Ramiro1, Pedro Machado2, Raquel Roque3, Helena Santos4, Joaquim Polido-Pereira5, Daniela Peixoto6, Cátia Duarte7, Fernando Pimentel-Santos8, Cândida Silva4, J. E. Fonseca5, Filipa Teixeira6, Andrea Marques7, Filipe Araújo8, Jaime C. Branco8, José Pereira Da-Silva7, José Costa6, Jose A. Pereira Da Silva9, Luis Cunha Miranda4, J. Canas da Silva3, Helena Canhão5, A.M. Van Tubergen10, Desirée van der Heijde11, Robert Landewé12 and MJ Santos3, 1Hospital Garcia de Orta, Almada, Portugal and Academic Medical Center, University of Amsterdam, Amsterdam, Netherlands, 2Hospitais da Universidade de Coimbra, Coimbra, Portugal and Leiden University Medical Center, Leiden, Netherlands, 3Hospital Garcia de Orta, Almada, Portugal, 4Instituto Português de Reumatologia, Lisboa, Portugal, 5Instituto de Medicina Molecular, Faculdade de Medicina da Universidade de Lisboa and Rheumatology Department, Centro Hospitalar de Lisboa Norte, EPE, Hospital de Santa Maria, Lisboa, Portugal, 6Centro Hospitalar do Alto Minho, Hospital de Ponte de Lima, Ponte de Lima, Portugal, 7Hospitais da Universidade de Coimbra, Coimbra, Portugal, 8Centro Hospitalar de Lisboa Ocidental, Hospital Egas Moniz, Lisboa, Portugal, 9Centro Hospitalar de Lisboa Norte, Hospital de Santa Maria, Lisboa, Portugal, 10Maastricht University Medical Center, Maastricht, Netherlands, 11Leiden University Medical Center, Leiden, Netherlands, 12Academic Medical Center, University of Amsterdam, Amsterdam, Netherlands
Hospital
Serum IL-21 Is Increased and Associated with Higher Disease Activity and Higher Serum Levels of Markers of B-Cell Activation in Primary Sjögren's Syndrome
Jacques-Eric Gottenberg1, Ghada Alsaleh1, Corinne Miceli-Richard2, Raphaèle Seror3, Joelle Benessiano4, Valerie Devauchelle-Pensec5, Philippe Dieude6, Jean Jacques Dubost7, Anne-Laure Fauchais8, Vincent Goeb9, Eric Hachulla10, Pierre yves Hatron11, C. Larroche12, Véronique Le Guern13, Jacques Morel14, Aleth Perdriger15, Xavier Puechal16, Stephanie Rist17, Alain Saraux18, Damien Sène19, Jean Sibilia20, Karine Inamo21, Philippe Ravaud22 and Xavier Mariette23, 1Strasbourg University Hospital, Strasbourg, France, 2Hopital Bicêtre, Le Kremlin Bicêtre, France, 3Bicetre university hospital, LE Kremlin-Bicetre, France, 4Rheumatology, Paris Unervisity Hospital BICHAT, France, 5Brest Occidentale university, Brest, France, 6APHP, Hopital Bichat, Paris, France, 7CHU Gabriel Montpied, Clermont-Ferrand, France, 8Hospital, Limoges, France, 9Rheumatology, Rouen Unervisity Hospital, France, France, 10Internal Medicine, Lille CEDEX, France, 11Service de médecine interne, Hôpital Claude Huriez, Université Lille II, Lille, France, Paris, France, 12Hospital University Bobigny, France, 13Cochin Hospital, Paris, France, 14Hopital Lapeyronie, Montpellier, France, 15Hôpital Sud, Rennes, France, 16Le Mans General Hospital, Le Mans, France, 17Hospital University Orléans, France, 18CHU de la Cavale Blanche, Brest Cedex, France, 19Pitie-Salpetriere Hospital, Paris, France, 20Service de rhumatologie, Hôpitaux Universitaires de Strasbourg, Strasbourg, France, Strasbourg, France, 21Nihon Univ Hikarigoaka Hosp, Nerima-ku Tokyo, Japan, 22Hopital Hotel Dieu, Paris Descartes University, Paris, France, 23Université Paris-Sud, Le Kremlin Bicetre, France

Comparison of the SF-36 Vs. Lupus Qol in Measuring Health-Related Quality of Life in Systemic Lupus Erythematosus Women with and without Activity
Claudia Mendoza-Pinto1, Mario Garcia-Carrasco Sr.1, Socorro Mendez-Martinez1, Oscar Pazarán1, Mario H. Cardiel2 and Aurelio Lopez-Colombo3, 1HGR 36 CMN Manuel Ávila Camacho, Instituto Mexicano del Seguro Social, Puebla, Mexico, 2Hospital, Morelia, Mexico, 3Delegación Estatal, Instituto Mexicano del Seguro Social, Puebla, Mexico
Hospital "Ramón y Cajal"
Response to Local Corticosteroid Injection In Carpal Tunnel Syndrome with Normal Electrodiagnostic Study
Domingo Ly-Pen1, José Luis Andreu2, Isabel Millán3, Gema de Blas4 and Alberto Sánchez-Olaso4, 1SERMAS. CS "Gandhi" / Hospital "Ramón y Cajal", Madrid, Spain, 2HU, Madrid, Spain, 3HU "Puerta de Hierro Majadahonda", Madrid, Spain, 4Hospital "Ramón y Cajal", Madrid, Spain
Hospital 12 de octubre
The Lupus Damage Index Questionnaire and Its Correlation with the SLICC/ACR Damage Index and the LupusQoL in a Spanish Multicenter Lupus Cohort. Is It Really Measuring Damage?
José M. Pego-Reigosa1, Íñigo Rúa-Figueroa2, Teresa Otón-Sánchez1, Manuela Fontanillo-Fontanillo1, María Galindo-Izquierdo3, Esther Uriarte-Isacelaya4, Bruno Aspe-de la Iglesia5, Laura Cáceres-Martín2 and Félix Francisco-Hernández2, 1Hospital do Meixoeiro, Vigo, Spain, 2Hospital Universitario Dr Negrín, Las Palmas de Gran Canaria, Spain, 3Hospital 12 de octubre, Madrid, Spain, 4Donosti, Spain, 5Vigo, Spain
Hospital AC Camargo
PET-CT, Interleukins and Metalloproteinases to Assess Disease Activity in  Takayasu Arteritis Patients
Anne E.D. Arraes1, Alexandre W.S. Souza1, Eduardo N.P. Lima2 and Emilia I. Sato1, 1Escola Paulista de Medicina - Universidade Federal de São Paulo, Sao Paulo, Brazil, 2Hospital AC Camargo, São Paulo, Brazil
Hospital at Slagelse
Short- and Long-Term Effect of Unguided, Intra-Articular Injections with Betamethasone In Early Rheumatoid Arthritis. Impact of Joint Area, Repeated Injections, MRI Findings, Anti-CCP, IgM-RF and CRP
Merete L. Hetland1, Mikkel Østergaard2, Bo J. Ejbjerg3, Søren Jacobsen4, Kristian Stengaard-Pedersen5, Peter Junker6, Tine Lottenburger6, Ib Hansen7, Lis Smedegaard Andersen8, Ulrik Tarp9, Anders Svendsen10, Jens Kristian Pedersen6, Henrik Skjødt11, Torkell Ellingsen12, Hanne M. Lindegaard6 and Kim Hørslev-Petersen13, 1Copenhagen University Hospital at Glostrup, on behalf of DANBIO, Copenhagen, Denmark, 2Copenhagen University Hospital in Glostrup, Glostrup, Denmark, 3Hospital at Slagelse, Slagelse, Denmark, 4Copenhagen University Hospital, Copenhagen, Denmark, 5Department of Rheumatology, Aarhus University Hospital, Aarhus, Denmark, 6Odense University Hospital, Odense C, Denmark, 7Viborg Hospital, Viborg, Denmark, 8Denmark, 9Aarhus University Hospital, Aarhus, Denmark, 10Odense, Denmark, 11Copenhagen University Hospital at Glostrup, Copenhagen, Denmark, 12University Hospital, Silkeborg, Denmark, 13University of Southern Denmark, Graasten, Denmark
Hospital Barmherzige Brueder, Graz- Eggenberg
Clinical Response and B Cell Analysis by High-Sensitive Flowcytometry After the Second Course of Rituximab
Hans-Peter Brezinschek1, Franz Rainer2, Kerstin Brickmann1, Raimund Lunzer2 and Winfried B. Graninger1, 1Medical University Graz, Graz, Austria, 2Hospital Barmherzige Brueder, Graz- Eggenberg, Austria
Hospital Británico de Buenos Aires
Safety Profile of Belimumab, a B-Lymphocyte Stimulator–Specific Inhibitor, in Phase 2 and 3 Clinical Trials of Patients with Active Systemic Lupus Erythematosus
D.J. Wallace1, S. Navarra2, M. Petri3, A. Gallacher4, R. Gúzman5, M. Thomas6, R.A. Furie7, O. Zamani8, R.A. Levy9, R.F. van Vollenhoven10, S. Cooper11, Z.J. Zhong11, W. Freimuth11, L. Pineda11, R. Cervera12 and BLISS-52 and -76 and LBSL02/99 Study Groups13, 1Cedars-Sinai/UCLA, Los Angeles, CA, 2University of Santo Tomas Hospital, Manila, Philippines, 3Johns Hopkins University School of Medicine, Baltimore, MD, 4Hospital Británico de Buenos Aires, Buenos Aires, Argentina, 5IDEARG, SaludCoop, Bogotá, Colombia, 6Kerala Institute of Medical Sciences, Kerala, India, 7North Shore-LIJ Health System, Lake Success, NY, 8Rheumazentrum Favoriten, Wien, Austria, 9Hospital Universitário Pedro Ernesto, Rio de Janeiro, Brazil, 10The Karolinska Institute, Stockholm, Sweden, 11Human Genome Sciences, Inc., Rockville, MD, 12Hospital Clinic, Barcelona, Spain, 13Multicenter
Hospital Carlos Haya
Biologics use in SLE in 23 Centers - Data from the International Registry for Biologics In SLE (IRBIS)
R.F. van Vollenhoven1, Søren Jacobsen2, Daniel Wallace3, John G. Hanly4, Michelle Petri5, David A. Isenberg6, Sasha Bernatsky7, Sang-Cheol Bae8, Manuel Ramos-Casals9, Guillermo Ruiz-Irastorza10, Francisco J. García-Hernández11, Luis Saez12, José Luis Callejas13, Javier Rascón14, Enrique de Ramón15, Mª Mar Ayala-Gutiérrez15, Maite Camps15, Melinda Mild16, Murat Inanç17, Bahar Artim-Esen17, Rosalind Ramsey-Goldman18, Christine A. Peschken19, Danilo Squatrito20, László Kovács21, Andrea Doria22, Zoltan Szekanecz23, Elisa Gremese24 and Emilia I. Sato25, 1Karolinska University Hospital, Stockholm, Sweden, 2Copenhagen University Hospital, Copenhagen, Denmark, 3Cedars-Sinai/UCLA, Los Angeles, CA, 4Dalhousie University and Capital Health, Halifax, NS, 5Johns Hopkins Hospital, Baltimore, MD, 6University College London, London, United Kingdom, 7McGill UHC/RVH, Montreal, QC, 8Hanyang University Hospital for Rheumatic Diseases, Seoul, South Korea, 9Hospital Clínic, Barcelona, Spain, 10Hospital de Cruces, Bizkaia, Spain, 11Hospital Virgen del Rocío, Sevilla, Spain, 12Hospital Miguel Servet, Zaragoza, Spain, 13Hospital San Cecilio, Granada, Spain, 14Hospital Son Dureta, Palma de Mallorca, Spain, 15Hospital Carlos Haya, Málaga, Spain, 16Karolinska Institutet, Stockholm, Sweden, 17Istanbul University, Istanbul Medical Faculty, Istanbul, Turkey, 18Northwestern University Feinberg School of Medicine, Chicago, IL, 19Univ of Manitoba, Winnipeg, MB, 20Careggi Hospital- Florence, Florence, Italy, 21University of Szeged, Szeged, Hungary, 22University of Padova, Padova, Italy, 23University of Debrecen Medical and Health Sciences Center, Debrecen, Hungary, 24Rheumatology Unit, Catholic University, Roma, Italy, 25Escola Paulista de Medicina - Universidade Federal de São Paulo, Sao Paulo, Brazil
Hospital Central y Facultad de Medicina, Universidad Autónoma de San Luis Potosí
Methotrexate Every Day Is Safe and Effective As Weekly Dosage
Ricardo Moreno-Valdes1, Marco Ulises Martinez-Martinez1, Enrique Cuevas-Orta1, Jorge Alcocer-Varela2 and Carlos Abud-Mendoza3, 1Hospital Central,, San Luis Potosí, Mexico, 2Instituto Nacional de Ciencias Médicas y Nutrición, Salvador Zubirán, Mexico city, Mexico, 3Hospital Central y Facultad de Medicina, Universidad Autónoma de San Luis Potosí, San Luis Potosi, Mexico
Hospital Central,
Methotrexate Every Day Is Safe and Effective As Weekly Dosage
Ricardo Moreno-Valdes1, Marco Ulises Martinez-Martinez1, Enrique Cuevas-Orta1, Jorge Alcocer-Varela2 and Carlos Abud-Mendoza3, 1Hospital Central,, San Luis Potosí, Mexico, 2Instituto Nacional de Ciencias Médicas y Nutrición, Salvador Zubirán, Mexico city, Mexico, 3Hospital Central y Facultad de Medicina, Universidad Autónoma de San Luis Potosí, San Luis Potosi, Mexico
Hospital Civil JIM
R577X Alpha-Actinin 3 (ACTN3) polymorphism Is Associated with Inflammatory Myopathies in Mexican population 
Flavio Sandoval- Garcia1, Marcelo Petri2, Miguel A. Saavedra3, Claudia Cruz-Reyes4, Luis Jara-Quezada3, Ingrid Dávalos5, Mario Salazar-Páramo6, Ivan Gámez-Nava7, Laura Gonzalez-Lopez8, Trinidad García-Iglesias9, Esther Corona-Sánchez10, Soraya Zavaleta-Muñiz11, Raúl Vargas-Ramírez10, Jorge Aguilar Arreola12, Monica Vázquez-Del Mercado11 and Beatriz T. Martín-Márquez13, 1Instituto de Investigación en Reumatología y del Sistema Músculo Esquelético, Universidad de Guadalajara, Guadalajara, Jalisco, Mexico, Mexico, 2Universidad de Guadalajara, Guadalajara, Jalisco, Mexico, Mexico, 3Centro Medico La Raza Instituto Mexicano del Seguro Social Mexico D.F., México D.F., Mexico, 4Centro Medico La Raza Instituto Mexicano del Seguro Social Mexico D.F., Mexico D. F., Mexico, 5Departamento de Biologia Molecular y Genomica, Instituto de Genetica Humana, Centro Universitario de Ciencias de la Salud, Universidad de Guadalajara, Guadalajara, Jalisco, Mexico, Mexico, 6Departamento de Fisiología, Centro Universitario de Ciencias de la Salud, Universidad de Guadalajara, Guadalajara, Jalisco, Mexico, Mexico, 7Centro Médico Nacional de Occidente, IMSS, Guadalajara, Jalisco, México., Mexico, 8Hospital Regional de Zona 110, Instituto Mexicano del Seguro Social (IMSS), Guadalajara, Jalisco, Mexico, Guadalajara, Jalisco, Mexico, Mexico, 9Laboratorio de Inmunología, Centro Universitario de Ciencias de la Salud, Universidad de Guadalajara, Guadalajara, Jalisco, Mexico, Mexico, 10Instituto de Investigación en Reumatología y del Sistema Músculo Esquelético, Universidad de Guadalajara, Guadalajara, Jalisco, México, Mexico, 11Universidad de Guadalajara, Guadalajara, Jalisco, México, Mexico, 12Hospital Civil JIM, 13Universidad de Guadalajara, Gudalajara, Jalisco, México, Mexico
Hospital Clínic
No Ultrasound Specific Changes in Trochanter Enthesis in Patients with Greater Trochanter Pain Syndrome and Chronic Arthritis
Julio Ramírez1, Isaac Pomés1, Jaume Pomés1 and Juan D. Cañete2, 1Hospital Clínic, Barcelona, Spain, 2Hospital Clínic de Barcelona, IDIBAPS, Barcelona, Spain

Biologics use in SLE in 23 Centers - Data from the International Registry for Biologics In SLE (IRBIS)
R.F. van Vollenhoven1, Søren Jacobsen2, Daniel Wallace3, John G. Hanly4, Michelle Petri5, David A. Isenberg6, Sasha Bernatsky7, Sang-Cheol Bae8, Manuel Ramos-Casals9, Guillermo Ruiz-Irastorza10, Francisco J. García-Hernández11, Luis Saez12, José Luis Callejas13, Javier Rascón14, Enrique de Ramón15, Mª Mar Ayala-Gutiérrez15, Maite Camps15, Melinda Mild16, Murat Inanç17, Bahar Artim-Esen17, Rosalind Ramsey-Goldman18, Christine A. Peschken19, Danilo Squatrito20, László Kovács21, Andrea Doria22, Zoltan Szekanecz23, Elisa Gremese24 and Emilia I. Sato25, 1Karolinska University Hospital, Stockholm, Sweden, 2Copenhagen University Hospital, Copenhagen, Denmark, 3Cedars-Sinai/UCLA, Los Angeles, CA, 4Dalhousie University and Capital Health, Halifax, NS, 5Johns Hopkins Hospital, Baltimore, MD, 6University College London, London, United Kingdom, 7McGill UHC/RVH, Montreal, QC, 8Hanyang University Hospital for Rheumatic Diseases, Seoul, South Korea, 9Hospital Clínic, Barcelona, Spain, 10Hospital de Cruces, Bizkaia, Spain, 11Hospital Virgen del Rocío, Sevilla, Spain, 12Hospital Miguel Servet, Zaragoza, Spain, 13Hospital San Cecilio, Granada, Spain, 14Hospital Son Dureta, Palma de Mallorca, Spain, 15Hospital Carlos Haya, Málaga, Spain, 16Karolinska Institutet, Stockholm, Sweden, 17Istanbul University, Istanbul Medical Faculty, Istanbul, Turkey, 18Northwestern University Feinberg School of Medicine, Chicago, IL, 19Univ of Manitoba, Winnipeg, MB, 20Careggi Hospital- Florence, Florence, Italy, 21University of Szeged, Szeged, Hungary, 22University of Padova, Padova, Italy, 23University of Debrecen Medical and Health Sciences Center, Debrecen, Hungary, 24Rheumatology Unit, Catholic University, Roma, Italy, 25Escola Paulista de Medicina - Universidade Federal de São Paulo, Sao Paulo, Brazil

Subacromial Steroid Injection Do Not Seems to Increase the Rate of Full-Thickness Rotator Cuff Tear
Julio Ramirez1, Isaac Pomés2, Jaume Pomés2 and Juan D. Cañete3, 1Hospital Clinic, Barcelona, Spain, 2Hospital Clínic, Barcelona, Spain, 3Hospital Clínic de Barcelona, IDIBAPS, Barcelona, Spain
Hospital Clinic
Safety Profile of Belimumab, a B-Lymphocyte Stimulator–Specific Inhibitor, in Phase 2 and 3 Clinical Trials of Patients with Active Systemic Lupus Erythematosus
D.J. Wallace1, S. Navarra2, M. Petri3, A. Gallacher4, R. Gúzman5, M. Thomas6, R.A. Furie7, O. Zamani8, R.A. Levy9, R.F. van Vollenhoven10, S. Cooper11, Z.J. Zhong11, W. Freimuth11, L. Pineda11, R. Cervera12 and BLISS-52 and -76 and LBSL02/99 Study Groups13, 1Cedars-Sinai/UCLA, Los Angeles, CA, 2University of Santo Tomas Hospital, Manila, Philippines, 3Johns Hopkins University School of Medicine, Baltimore, MD, 4Hospital Británico de Buenos Aires, Buenos Aires, Argentina, 5IDEARG, SaludCoop, Bogotá, Colombia, 6Kerala Institute of Medical Sciences, Kerala, India, 7North Shore-LIJ Health System, Lake Success, NY, 8Rheumazentrum Favoriten, Wien, Austria, 9Hospital Universitário Pedro Ernesto, Rio de Janeiro, Brazil, 10The Karolinska Institute, Stockholm, Sweden, 11Human Genome Sciences, Inc., Rockville, MD, 12Hospital Clinic, Barcelona, Spain, 13Multicenter

Patient-Perceived Impact of Psoriatic Arthritis Is Due to Pain and Fatigue, but Also to Psychological Aspects- the Psa Impact of Disease Study
Laure Gossec1, Maarten de Wit2, Andra Balanescu3, Peter V. Balint4, Gabor Békés4, Juergen Braun5, Juan D. Canete6, Laurence Carton7, Alina Dinte8, Kurt L. De Vlam9, Turid Heiberg10, Philip Helliwell11, Umut Kalyoncu12, Uta Kiltz13, Thomas Luger14, Mara Maccarone15, Ronan H. Mullan16, Dennis O'Sullivan16, Kati Otsa17, Andrew Parkinson18, Anselm Sanchez Lombarte6, Rossana Scrivo19, Josef Smolen20, Tanja A. Stamm21 and Tore K. Kvien22, 1Cochin Hospital, Paris, France, 2Dutch Arthritis Patient League, Amersfoort, Netherlands, 3University of Medicine and Pharmacy "Carol Davila", Bucharest, Romania, 4National Institute of Rheumatology and Physiotherapy, Budapest, Hungary, 5Ruhr-University Bochum, Herne, Germany, 6Hospital Clinic, Barcelona, Spain, 7Cochin Hospital and Association Française de Lutte Anti-Rhumatismale, Paris, France, 8“Sf. Maria” Hospital, Bucharest, Romania, 9University Hospital, Leuven, Belgium, 10Ullevaal Univ Hospital, Oslo, Norway, 11NIHR-Leeds Biomedical Research Unit and Leeds Institute of Molecular Medicine, University of Leeds, Leeds, United Kingdom, 12Hacettepe University Faculty of Medicine, Ankara, Turkey, 13Rheumazentrum Ruhrgebiet, Herne, Germany, 14University Hospital Münster, Münster, Germany, 15Associazione per la Difesa degli Psoriasici, Rome, Italy, 16St Vincent's University Hospital, Dublin, Ireland, 17Tallinn Central Hospital, Tallinn, Estonia, 18University of Leeds, Leeds, United Kingdom, 19Reumatologia - Sapienza Università di Roma, Rome, Italy, 20Medical University of Vienna and Hietzing Hospital, Vienna, Austria, 21Medical University of Vienna, Vienna, Austria, 22Diakonhjemmet Hospital, Oslo, Norway

Synovial Cytokine Expression in Psoriatic Arthritis and Associations with Lymphoid Neogenesis and Clinical Features
Raquel Celis1, Raimon Sanmarti1, Julio Ramirez2, Antonio Palacin2, Jose L. Pablos3 and Juan D. Cañete4, 1Clinic Hospital, Barcelona, Spain, 2Hospital Clinic, Barcelona, Spain, 3Instituto de Investigación Hospital 12 de Octubre (I+12), Madrid, Spain, 4Hospital Clínic de Barcelona, IDIBAPS, Barcelona, Spain

Factors Associated with Belimumab Treatment Benefit: Results From Phase 3 Studies in Patients with Systemic Lupus Erythematosus
R.F. van Vollenhoven1, M. Petri2, R. Cervera3, C. Kleoudis4, Z.J. Zhong5, D. Roth6, W. Freimuth5 and BLISS-52 and BLISS-76 Study Groups7, 1The Karolinska Institute, Stockholm, Sweden, 2Johns Hopkins University School of Medicine, Baltimore, MD, 3Hospital Clinic, Barcelona, Spain, 4GlaxoSmithKline, Durham, NC, 5Human Genome Sciences, Inc., Rockville, MD, 6GlaxoSmithKline, King of Prussia, PA, 7Multicenter

Synovial Tissue Cytokine Expression in Rheumatoid Arthritis and Associations with Lymphoid Neogenesis, Disease Activity and the European League Against Rheumatism Response
Juan D. Canete1, Raquel Celis2, Julio Ramirez1, Sara Marsal3, Gabriel Avila3, Raimon Sanmarti2 and Jose L. Pablos4, 1Hospital Clinic, Barcelona, Spain, 2Clinic Hospital, Barcelona, Spain, 3Hospital Vall de Hebró, Grup de Recerca de Reumatologia, Barcelona, Spain, 4Instituto de Investigación Hospital 12 de Octubre (I+12), Madrid, Spain

Subacromial Steroid Injection Do Not Seems to Increase the Rate of Full-Thickness Rotator Cuff Tear
Julio Ramirez1, Isaac Pomés2, Jaume Pomés2 and Juan D. Cañete3, 1Hospital Clinic, Barcelona, Spain, 2Hospital Clínic, Barcelona, Spain, 3Hospital Clínic de Barcelona, IDIBAPS, Barcelona, Spain
Hospital Clínic / IDIBAPS
Clinical and Genetic Features of Autoinflammatory Syndromes in Hispanic Patients: The Chilean Experience
Cristian Vergara1, Arturo Borzutzky1, Miguel A. Gutierrez1, Sergio Iacobelli1, Eduardo Talesnik1, Maria Eugenia Martinez1, Lilith Stange1, Javier Basualdo2, Viviana Maluje3, Renato Jimenez4, Elena Jarpa5, Roberto Wiener6, Javier Tinoco6, Juan I. Arostegui7, Jordi Yague7 and Manuel Alvarez-Lobos1, 1Pontificia Universidad Catolica de Chile, Santiago, Chile, 2Universidad de Chile, Santiago, Chile, 3Hospital FACH, Santiago, Chile, 4Hospital Gustavo Fricke, Valparaiso, Chile, 5Hospital Naval Almirante Nef, Vina Del Mar, Chile, 6Hospital Militar, Santiago, Chile, 7Hospital Clínic / IDIBAPS, Barcelona, Spain
Hospital Clínic de Barcelona,
Smoking Impact on Radiographic Progression in An Early Rheumatoid Arthritis Cohort
Virginia Ruiz-Esquide1, Jose Alfredo Gomez Puerta2, S. Cabrera1, J. D. Cañete3, M. V. Hernandez2, Eduard Graell4, Guadalupe Ercilla1, Odette Viñas1, M. J. Gómara5, Isabel Haro5 and Raimon Sanmarti2, 1Hospital Clinic of Barcelona., Barcelona, Spain, 2Hospital Clinic of Barcelona, Barcelona, Spain, 3Hospital Clínic de Barcelona,, Barcelona, Spain, 4Hospital Parc Tauli, Sabadell, Spain, 5IQAC-CSIC, Barcelona, Spain
Hospital Clínic de Barcelona, IDIBAPS
No Ultrasound Specific Changes in Trochanter Enthesis in Patients with Greater Trochanter Pain Syndrome and Chronic Arthritis
Julio Ramírez1, Isaac Pomés1, Jaume Pomés1 and Juan D. Cañete2, 1Hospital Clínic, Barcelona, Spain, 2Hospital Clínic de Barcelona, IDIBAPS, Barcelona, Spain

The New EULAR/ACR Classification ACPA Cutoff Levels Are Markers of Poor Radiological Outcome in Early Rheumatoid Arthritis
Jose Alfredo Gomez Puerta1, Virginia Ruiz Esquide1, M. V. Hernandez1, Eduard Graell2, Sonia Cabrera3, M. J. Gómara4, Juan D. Cañete5, Isabel Haro4 and R. Sanmarti1, 1Hospital Clinic of Barcelona, Barcelona, Spain, 2Hospital Parc Tauli, Sabadell, Spain, 3Hospital Clinic of Barcelona., Barcelona, Spain, 4IQAC-CSIC, Barcelona, Spain, 5Hospital Clínic de Barcelona, IDIBAPS, Barcelona, Spain

Synovial Cytokine Expression in Psoriatic Arthritis and Associations with Lymphoid Neogenesis and Clinical Features
Raquel Celis1, Raimon Sanmarti1, Julio Ramirez2, Antonio Palacin2, Jose L. Pablos3 and Juan D. Cañete4, 1Clinic Hospital, Barcelona, Spain, 2Hospital Clinic, Barcelona, Spain, 3Instituto de Investigación Hospital 12 de Octubre (I+12), Madrid, Spain, 4Hospital Clínic de Barcelona, IDIBAPS, Barcelona, Spain

Identification of Robust and Disease-Specific Stromal Alterations in Spondyloarthritis Synovitis
Nataliya Yeremenko1, Gemma M. M. Rigter1, Iris Simon2, Juan D. Cañete3, Paul P. Tak1 and Dominique L. Baeten1, 1Academic Medical Center/University of Amsterdam, Amsterdam, Netherlands, 2Agendia BV, Amsterdam, Netherlands, 3Hospital Clínic de Barcelona, IDIBAPS, Barcelona, Spain

Transcriptome Analysis Reveals a Robust Profile In Osteoarthritis Synovial Fibroblasts
Manuel J. Del Rey1, Alicia Usategui1, Elena Izquierdo1, Vanessa Miranda1, Juan D. Cañete2, Francisco J. Blanco Sr.3, Gabriel Criado1 and Jose L. Pablos1, 1Instituto de Investigación Hospital 12 de Octubre (I+12), Madrid, Spain, 2Hospital Clínic de Barcelona, IDIBAPS, Barcelona, Spain, 3INIBIC-CHUAC, La Coruna, Spain

Subacromial Steroid Injection Do Not Seems to Increase the Rate of Full-Thickness Rotator Cuff Tear
Julio Ramirez1, Isaac Pomés2, Jaume Pomés2 and Juan D. Cañete3, 1Hospital Clinic, Barcelona, Spain, 2Hospital Clínic, Barcelona, Spain, 3Hospital Clínic de Barcelona, IDIBAPS, Barcelona, Spain
Hospital Clínic de Barcelona.
Dermatologicals Manifestations Induced by Tumor Necrosis Factor Antagonists Therapy in Rheumatic Diseases. Incidence Rate in BIOBADASER 2.0 Registry
Maria Victoria Hernández Miguel1, Miguel A. Descalzo2, Loreto Carmona3, Melina Meineri1, Sonia Cabrera4, Maria Eugenia Gomez Caballero4, Jose Alfredo Gomez Puerta1, Virginia Ruiz Esquide1, Julio Ramirez1, Juan D. Cañete5 and Raimon Sanmarti1, 1Hospital Clinic of Barcelona, Barcelona, Spain, 2Spanish Society of Rheumatology, Madrid, Spain, 3Universidad Camilo José Cela, Villanueva de la Cañada, Spain, 4Hospital Clinic of Barcelona., Barcelona, Spain, 5Hospital Clínic de Barcelona., Barcelona, Spain
Hospital Clinic of Barcelona
The New EULAR/ACR Classification ACPA Cutoff Levels Are Markers of Poor Radiological Outcome in Early Rheumatoid Arthritis
Jose Alfredo Gomez Puerta1, Virginia Ruiz Esquide1, M. V. Hernandez1, Eduard Graell2, Sonia Cabrera3, M. J. Gómara4, Juan D. Cañete5, Isabel Haro4 and R. Sanmarti1, 1Hospital Clinic of Barcelona, Barcelona, Spain, 2Hospital Parc Tauli, Sabadell, Spain, 3Hospital Clinic of Barcelona., Barcelona, Spain, 4IQAC-CSIC, Barcelona, Spain, 5Hospital Clínic de Barcelona, IDIBAPS, Barcelona, Spain

Dermatologicals Manifestations Induced by Tumor Necrosis Factor Antagonists Therapy in Rheumatic Diseases. Incidence Rate in BIOBADASER 2.0 Registry
Maria Victoria Hernández Miguel1, Miguel A. Descalzo2, Loreto Carmona3, Melina Meineri1, Sonia Cabrera4, Maria Eugenia Gomez Caballero4, Jose Alfredo Gomez Puerta1, Virginia Ruiz Esquide1, Julio Ramirez1, Juan D. Cañete5 and Raimon Sanmarti1, 1Hospital Clinic of Barcelona, Barcelona, Spain, 2Spanish Society of Rheumatology, Madrid, Spain, 3Universidad Camilo José Cela, Villanueva de la Cañada, Spain, 4Hospital Clinic of Barcelona., Barcelona, Spain, 5Hospital Clínic de Barcelona., Barcelona, Spain

A Significant Proporcion of Patients with Palindromic Rheumatism and Positive Anti-Citrulinated Protein Antibodies Do Not evolve to Rheumatoid Arthritis after  a Long Term Follow-up
S. Cabrera1, J. A. Gomez- Puerta1, M. V. Hernandez1, V. Ruiz -Esquide1, Georgina Salvador2, M.E. Gomez -Caballero1, J. Ramirez1, J. D. Cañete1 and R. Sanmarti1, 1Hospital Clinic of Barcelona, Barcelona, Spain, 2Hospital Mutua de Terrassa. Barcelona, Barcelona, Spain

Changes in Psychological Status in Patients with Chronic Spondyloarthropathy Treated with Infliximab
Rosa M. Morlà1, Hector Corominas2, M. V. Hernandez3, Mireia Moreno4, Miquel Sala5, Vera Ortiz-Santamaria6, Patricia Reyner6, Vicente Torrente-Segarra Jr.7, Agusti Sellas Fernandez8, Georgina Salvador9, Elena Sirvent10, Cristina Masuet11 and Xavier Juanola-Roura12, 1Hospital Sta Tecla, Tarragona, Spain, 2Hospital Moises Broggi, Barcelona, 3Hospital Clinic of Barcelona, Barcelona, Spain, 4Servei de Reumatologia, Sabadell, Spain, 5Rheumatology Unit, Figueres, Spain, 6Unitat de Reumatologia, Spain, 7Hospital General de Hospitalet, Barcelona, Spain, 8Senior Consultant, Barcelon, Spain, 9Hospital Mutua de Terrassa. Barcelona, Barcelona, Spain, 10Hospital de Sant Boi, 11Hospital de Bellvitge, Hospitalet de LLobregat, Spain, 12Hospital Universitario de Bellvitge, Barcelona, Spain

Smoking Impact on Radiographic Progression in An Early Rheumatoid Arthritis Cohort
Virginia Ruiz-Esquide1, Jose Alfredo Gomez Puerta2, S. Cabrera1, J. D. Cañete3, M. V. Hernandez2, Eduard Graell4, Guadalupe Ercilla1, Odette Viñas1, M. J. Gómara5, Isabel Haro5 and Raimon Sanmarti2, 1Hospital Clinic of Barcelona., Barcelona, Spain, 2Hospital Clinic of Barcelona, Barcelona, Spain, 3Hospital Clínic de Barcelona,, Barcelona, Spain, 4Hospital Parc Tauli, Sabadell, Spain, 5IQAC-CSIC, Barcelona, Spain
Hospital Clinic of Barcelona.
The New EULAR/ACR Classification ACPA Cutoff Levels Are Markers of Poor Radiological Outcome in Early Rheumatoid Arthritis
Jose Alfredo Gomez Puerta1, Virginia Ruiz Esquide1, M. V. Hernandez1, Eduard Graell2, Sonia Cabrera3, M. J. Gómara4, Juan D. Cañete5, Isabel Haro4 and R. Sanmarti1, 1Hospital Clinic of Barcelona, Barcelona, Spain, 2Hospital Parc Tauli, Sabadell, Spain, 3Hospital Clinic of Barcelona., Barcelona, Spain, 4IQAC-CSIC, Barcelona, Spain, 5Hospital Clínic de Barcelona, IDIBAPS, Barcelona, Spain

Dermatologicals Manifestations Induced by Tumor Necrosis Factor Antagonists Therapy in Rheumatic Diseases. Incidence Rate in BIOBADASER 2.0 Registry
Maria Victoria Hernández Miguel1, Miguel A. Descalzo2, Loreto Carmona3, Melina Meineri1, Sonia Cabrera4, Maria Eugenia Gomez Caballero4, Jose Alfredo Gomez Puerta1, Virginia Ruiz Esquide1, Julio Ramirez1, Juan D. Cañete5 and Raimon Sanmarti1, 1Hospital Clinic of Barcelona, Barcelona, Spain, 2Spanish Society of Rheumatology, Madrid, Spain, 3Universidad Camilo José Cela, Villanueva de la Cañada, Spain, 4Hospital Clinic of Barcelona., Barcelona, Spain, 5Hospital Clínic de Barcelona., Barcelona, Spain

Smoking Impact on Radiographic Progression in An Early Rheumatoid Arthritis Cohort
Virginia Ruiz-Esquide1, Jose Alfredo Gomez Puerta2, S. Cabrera1, J. D. Cañete3, M. V. Hernandez2, Eduard Graell4, Guadalupe Ercilla1, Odette Viñas1, M. J. Gómara5, Isabel Haro5 and Raimon Sanmarti2, 1Hospital Clinic of Barcelona., Barcelona, Spain, 2Hospital Clinic of Barcelona, Barcelona, Spain, 3Hospital Clínic de Barcelona,, Barcelona, Spain, 4Hospital Parc Tauli, Sabadell, Spain, 5IQAC-CSIC, Barcelona, Spain
Hospital Clínico San Carlos
Are Training Sessions Useful for Ultrasound Scan Evaluation of Synovitis In Rheumatoid Arthritis?
Andrés Ponce, Hospital General de Granollers, Granollers, Spain, Juan J. Alegre, Hospital Universitario Dr Peset, Valencia, Spain, Manuel Castaño, Hospital Universitario Virgen de la Arrixaca, Murcia, Spain, Ricardo Gutierrez-Polo, C.H. de Navarra, Pamplona, Spain, Francisco G. Jiménez-Núñez, Hospital Regional Universitario Carlos Haya., Malaga, Spain, María P. Macarrón, Hospital Clínico San Carlos, Madrid, Spain and Jesús Garrido, Facultad de Psicología.Universidad Autónoma de Madrid, Madrid, Spain

Adverse Events of Immunosuppressive Therapy in Autoimmune Uveitis Patients
Zulema Rosales, Ana B. Rodríguez-Cambrón, Oscar Fontsere, Leticia León, Pedro Arriola, Lydia Abásolo, Cristina Martínez, Cristina Lajas and Esperanza Pato, Hospital Clínico San Carlos, Madrid, Spain

Relationship BETWEEN PATTERNS of CLINICAL PRESENTATION Uveitis and FINAL Inmunologic DIAGNOSIS
Esperanza Pato1, Zulema Rosales1, Esther Toledano1, Pilar Macarron1, Cristina Vadillo1, Rosalía Mendez1, Miguel A. Descalzo2 and Estíbaliz Loza2, 1Hospital Clínico San Carlos, Madrid, Spain, 2Spanish Society of Rheumatology, Madrid, Spain

Adalimumab in 107 Refractory Uveitis: A Multicenter Study
Orlando Pompei1, Ricardo Blanco2, Manuel Diaz-llopis3, David Salom3, Carmen Garcia-Vicuña4, Miguel Cordero-Coma5, Gabriela Ortega-Larrocea6, Norberto Ortego-Centeno7, Marta Suarez-de-Figueroa8, J. Carlos Fernandez-Cid9, Alejandro Fonollosa10, Angel M. Garcia-Aparicio11, Jose M. Benítez-del-Castillo12, Jose L. Olea13 and J. Fernando Arevalo14, 1Hospital Universitario Marqués de Valdecilla. IFIMAV, Santander, Spain, 2Hospital Universitario Marqués de Valdecilla-IFIMAV, Santander, Spain, 3La Fe University Hospital of Valencia, Valencia, Spain, 4Hospital Sant Joan de Déu, Barcelona, Spain, 5Hospital de León, León, Spain, 6National Institute of Rehabilitation, D.F Mexico, Mexico, 7Hospital Clínico San Cecilio, Granada, Spain, 8Hospital Ramon y Cajal, Madrid, Spain, 9Hospital de Pontevedra, Pontevedra, Spain, 10Hospital de Cruces, Bilbao, Spain, 11Hospital Virgen de la Salud, Toledo, Spain, 12Hospital Clínico San Carlos, Madrid, 13Hospital Son Dureta, Palma de Mallorca, Spain, 14Ophthalmology Clinic Center of Caracas, Caracas, Venezuela

Detection of Adverse Events in Routine Rheumatology Practice by a New Computer Application
Zulema Rosales1, Ana B. Rodríguez-Cambrón1, Lydia Abásolo1, Leticia León1, Oscar Fontsere1, Cristina Vadillo1, J.L. Fernández Rueda1 and Juan A. Jover2, 1Hospital Clínico San Carlos, Madrid, Spain, 2Hospital Clinico San Carlos, Madrid, Spain
Hospital clinico San Carlos
Mechanisms Underlying the Generation of Soluble IL-6 Soluble Receptor (sIL-6R) in Rheumatoid Arthritis: mRNA Alternative Splicing and Proteolytic Cleavage As Independent Contributors
Jose Ramon Lamas1, Luis Rodriguez-Rodriguez2, Pilar Tornero-Esteban2, Lydia Abasolo2, Jezabel Varade1, Roberto Alvarez-Lafuente1, Esther Villafuertes2, Jose Hoyas2, Elena Urcelay1 and Benjamin Fernandez-Gutierrez2, 1Hospital clinico San Carlos, Madrid, Spain, 2Department of Rheumatology, Hospital Clinico San Carlos, Madrid, Spain

Expression of HUMAN Endogenous Retrovirus Herv-K18 In Osteoarthritis PATIENTS
Benjamin Fernandez-Gutierrez1, Marta Garcia-Montojo2, Jose Hoyas1, Inmaculada Dominguez-Mozo2, Esther Villafuertes1, Pilar Tornero-Esteban1, Ana Arias-Leal2, Lydia Abasolo1, Roberto Alvarez-Lafuente2 and Jose Ramon Lamas2, 1Department of Rheumatology, Hospital Clinico San Carlos, Madrid, Spain, 2Hospital clinico San Carlos, Madrid, Spain
Hospital Clinico San Carlos
Detection of Adverse Events in Routine Rheumatology Practice by a New Computer Application
Zulema Rosales1, Ana B. Rodríguez-Cambrón1, Lydia Abásolo1, Leticia León1, Oscar Fontsere1, Cristina Vadillo1, J.L. Fernández Rueda1 and Juan A. Jover2, 1Hospital Clínico San Carlos, Madrid, Spain, 2Hospital Clinico San Carlos, Madrid, Spain
Hospital Clínico San Cecilio
Adalimumab in 107 Refractory Uveitis: A Multicenter Study
Orlando Pompei1, Ricardo Blanco2, Manuel Diaz-llopis3, David Salom3, Carmen Garcia-Vicuña4, Miguel Cordero-Coma5, Gabriela Ortega-Larrocea6, Norberto Ortego-Centeno7, Marta Suarez-de-Figueroa8, J. Carlos Fernandez-Cid9, Alejandro Fonollosa10, Angel M. Garcia-Aparicio11, Jose M. Benítez-del-Castillo12, Jose L. Olea13 and J. Fernando Arevalo14, 1Hospital Universitario Marqués de Valdecilla. IFIMAV, Santander, Spain, 2Hospital Universitario Marqués de Valdecilla-IFIMAV, Santander, Spain, 3La Fe University Hospital of Valencia, Valencia, Spain, 4Hospital Sant Joan de Déu, Barcelona, Spain, 5Hospital de León, León, Spain, 6National Institute of Rehabilitation, D.F Mexico, Mexico, 7Hospital Clínico San Cecilio, Granada, Spain, 8Hospital Ramon y Cajal, Madrid, Spain, 9Hospital de Pontevedra, Pontevedra, Spain, 10Hospital de Cruces, Bilbao, Spain, 11Hospital Virgen de la Salud, Toledo, Spain, 12Hospital Clínico San Carlos, Madrid, 13Hospital Son Dureta, Palma de Mallorca, Spain, 14Ophthalmology Clinic Center of Caracas, Caracas, Venezuela

The IRF7 Region Is Associated with Anti-Centromere Autoantibody Production in Systemic Sclerosis Patients
F. David Carmona1, Ramana Gutala2, Carmen P. Simeón3, Patricia E. Carreira4, Norberto Ortego-Centeno5, Esther Vicente-Rabaneda6, Francisco J. García-Hernández7, Paloma García de la Peña8, Mónica Fernández-Castro9, Lina Martínez-Estupiñán10, María-Victoria Egurbide11, Spanish Scleroderma Group, Betty P. Tsao13, Pravitt R. Gourh14, Sandeep K. Agarwal15, Shervin Assassi16, Maureen D. Mayes15, Frank C. Arnett15, Filemon K. Tan15 and Javier Martín17, 1Consejo Superior de Investigaciones Científicas, Armilla (Granada), Spain, 2The University of Texas Health Science Center, Houston, TX, 3Hospital Valle de Hebron, Barcelona, Spain, 4Instituto de Investigación Hospital 12 de Octubre (I+12), Madrid, Spain, 5Hospital Clínico San Cecilio, Granada, Spain, 6Hospital de la Princesa, Madrid, Spain, 7Hospital Virgen del Rocío, Sevilla, Spain, 8Hospital Universitario Madrid Norte Sanchinarro, Madrid, Spain, 9Hospital Puerta de Hierro, Madrid, Spain, 10Gregorio Marañón Hospital, Madrid, Spain, 11Hospital de Cruces, UPV/EHU, Barakaldo, Spain, Barakaldo, Spain, 12David Geffen School of Medicine University of California Los Angeles, Los Angeles, CA, 13UTHSC-Houston Medical School, Houston, TX, 14University of Texas Health Science Center at Houston, Houston, TX, 15Univ of Texas Health Science, Houston, TX, 16Consejo Superior de Investigaciones Científicas, Granada, Spain

Immunochip Genotyping of 1,884 Systemic Sclerosis Cases and 4,325 Controls Reveals Novel Associations
Maureen D. Mayes1, Olga Y. Gorlova2, Lara Bossini-Castillo3, Jose Ezequiel Martin4, Jun Ying2, Peter K. Gregersen5, Annette T. Lee6, Shervin Assassi1, Sandeep K. Agarwal1, Filemon K. Tan1, John D. Reveille1, Xiaodong Zhou1, Frank C. Arnett1, Fredrick M. Wigley7, Laura K. Hummers7, Marilyn Perry1, Carmen Pilar Simeon8, Patricia Carriera9, Norberto Ortego-Centeno10, Miguel Gonzalez-Gay11, the Spanish Scleroderma Group12 and Javier Martin13, 1University of Texas Health Science Center at Houston, Houston, TX, 2UT M. D. Anderson Cancer Center, Houston, TX, 3Consejo Superior de Investigaciones Científicas (CSIC), Armilla (Granada), Spain, 4Instituto de Parasitología y Biomedicina López-Neyra, IPBLN-CSIC, Armilla (Granada), Spain, 5Feinstein Institute Medical Reschearch, Manhasset, NY, 6Feinstein Institute Med Rsch, Manhasset, NY, 7Johns Hopkins University, Baltimore, MD, 8Hospital Valle de Hebron, Barcelona, Spain, 9Madrid, Spain, 10Hospital Clínico San Cecilio, Granada, Spain, 11Hospital Marques De Valdecilla, Santander, Spain, 12Granada, Spain, 13Instituto de Parasitologia y Biomedicina Lopez-Neyra (CSIC), Granada, Spain
Hospital Clinico Universitario
The Most Reliable Probe Position in An RA Wrist Is From Lister’s Tubercle to Digit III, the Zorro Study
Noelia Dopazo Gonzalez1, David F. Ten Cate2, Antonio Mera3, S.A. Insua Vilariño4, Nanno Swen5, E. Perez-Pampin4, Juan J. Gomez-Reino6 and Jolanda J. Luime7, 1Erasmus Medical Centre Rotterdam, Rotterdam, Netherlands, 2Erasmus Medical Center, Rotterdam, Netherlands, 3General Hospital, Santiago Compostela, Spain, 4University Clinical Hospital of Santiago de Compostela, Santiago de Compostela, Spain, 5Medical Center Alkmaar, Alkmaar, Netherlands, 6Hospital Clinico Universitario, Santiago, Spain, 7Erasmus MC - University Medical Center, Rotterdam, Netherlands

Early Versus Delayed Retreatment with Rituximab (RTX) in Relation to Long Term Clinical Response – Data From the CERERRA Collaboration
Elisabeth Lie1, Katerina Chatzidionysiou2, Evgeny L. Nasonov3, Galina Lukina3, Karel Pavelka4, Dan C. Nordström5, Matija Tomsic6, Cem Gabay7, Ioan Ancuta8, Piet LC van Riel9, Juan J. Gomez-Reino10, João E. Fonseca11, Merete L. Hetland12, Ulrik Tarp13, Ronald F. van Vollenhoven2 and Tore K. Kvien1, 1Diakonhjemmet Hospital, Oslo, Norway, 2Karolinska Institute, Stockholm, Sweden, 3Institute of Rheumatology, Moscow, Russia, 41Institute of Rheumatology, Department of Experimental Rheumatology, 1st Faculty of Medicine, Charles University in Prague, Prague, Czech Republic, 5ROB-FIN, Helsinki University Central Hospital, Helsinki, Finland, 6University Medical Centre Ljubjana, Ljubljana, Slovenia, 7Geneva University Hospitals, for the SCQM registry, Geneva, Switzerland, 8Cantacuzino Hospital, Bucharest, Romania, 9Radboud University Nijmegen Medical Centre, Nijmegen, Netherlands, 10Hospital Clinico Universitario, Santiago, Spain, 11Lisbon Academic Medical Center, on behalf of Rheumatic Diseases Portuguese Register (Reuma.pt), Lisbon, Portugal, 12Copenhagen University Hospital at Glostrup, on behalf of DANBIO, Copenhagen, Denmark, 13Aarhus University Hospital, Aarhus, Denmark

Clinical Response At Months 1–6 Can Predict Likelihood of Achieving Remission in Abatacept Plus Methotrexate-Treated Patients with Early Rheumatoid Arthritis
Yusuf Yazici, NYU Hospital for Joint Diseases, New York, NY, Jurgen Wollenhaupt, Schoen-Klinik Hamburg-Eilbek, Hamburg, Germany, Patrick Durez, Cliniques Universitaires Saint-Luc, Université Catholique de Louvain, Brussels, Belgium, Juan J. Gomez-Reino, Hospital Clinico Universitario, Santiago de Compostela, Spain, Walter Grassi, Università Politecnica delle Marche, Ancona, Italy, Manuela Le Bars, Bristol-Myers Squibb, Rueil-Malmaison, France, Corine Gaillez, Bristol-Myers Squibb, Rueil Malmaison, France, Coralie Poncet, Docs International, Issy les Moulineaux, France, Ayanbola Elegbe, Bristol-Myers Squibb, Princeton, NJ and Rene Westhovens, UZ Gasthuisburg, Leuven, Belgium

Efficacy of Different Doses of Rituximab for the Treatment of RA: Data From the CERERRA Collaboration
Katerina Chatzidionysiou1, Elisabeth Lie2, Evgeny L. Nasonov3, Galina Lukina3, Merete L. Hetland4, Ulrik Tarp5, Ioan Ancuta6, Karel Pavelka7, Dan C. Nordström8, Cem Gabay9, Helena Canhao10, Matija Tomsic11, Piet LC van Riel12, Juan J. Gomez-Reino13, Tore K. Kvien2 and Ronald F. van Vollenhoven1, 1Karolinska Institute, Stockholm, Sweden, 2Diakonhjemmet Hospital, Oslo, Norway, 3ARBITER, Institute of Rheumatology, Moscow, Russia, 4Copenhagen University Hospital at Glostrup, on behalf of DANBIO, Copenhagen, Denmark, 5Aarhus University Hospital, Aarhus, Denmark, 6Cantacuzino Hospital, Bucharest, Romania, 71Institute of Rheumatology, Department of Experimental Rheumatology, 1st Faculty of Medicine, Charles University in Prague, Prague, Czech Republic, 8ROB-FIN, Helsinki University Central Hospital, Helsinki, Finland, 9for the SCQM registry, University Hospitals of Geneva, Geneva, Switzerland, 10Lisbon Medical Academic Medical Center on behalf of Rheumatic Diseases Portuguese Register, Lisbon, Portugal, 11University Medical Centre Ljubjana, Ljubljana, Slovenia, 12Radboud University Nijmegen Medical Centre, Nijmegen, Netherlands, 13Hospital Clinico Universitario, Santiago, Spain

Seropositivity and Response to RTX: Data From the CERERRA Collaboration
Katerina Chatzidionysiou1, Elisabeth Lie2, Evgeny L. Nasonov3, Galina Lukina3, Merete L. Hetland4, Ulrik Tarp5, Ioan Ancuta6, Karel Pavelka7, Dan C. Nordström8, Cem Gabay9, Helena Canhao10, Matija Tomsic11, Piet LCM Van Riel12, Juan J. Gomez-Reino13, Tore K. Kvien2 and Ronald F. van Vollenhoven1, 1Karolinska Institute, Stockholm, Sweden, 2Diakonhjemmet Hospital, Oslo, Norway, 3ARBITER, Institute of Rheumatology, Moscow, Russia, 4DANBIO, Copenhagen University Hospital at Glostrup, Copenhagen, Denmark, 5Aarhus University Hospital, Aarhus, Denmark, 6Cantacuzino Hospital, Bucharest, Romania, 71Institute of Rheumatology, Department of Experimental Rheumatology, 1st Faculty of Medicine, Charles University in Prague, Prague, Czech Republic, 8ROB-FIN, Helsinki University Central Hospital, Helsinki, Finland, 9for the SCQM registry, University Hospitals of Geneva, Geneva, Switzerland, 10Hosp Santa Maria, Lisbon, Portugal, 11University Medical Centre Ljubjana, Ljubljana, Slovenia, 12Radboud University Nijmegen Medical Centre, Nijmegen, Netherlands, 13Hospital Clinico Universitario, Santiago, Spain

Evaluation of Remission Over 1 Year in Patients (pts) with Early Rheumatoid Arthritis (RA) Treated with Abatacept (ABA) Plus Methotrexate, According to Simplified Disease Activity Index (SDAI)
Josef Smolen1, J. Wollenhaupt2, Juan J. Gomez-Reino3, Walter Grassi4, Manuela Le Bars5, Corine Gaillez5, Coralie Poncet6, Ayanbola Elegbe7 and Rene Westhovens8, 1Medical University of Vienna and Hietzing Hospital, Vienna, Austria, 2Schön Klinik Hamburg-Eilbek, Hamburg, Germany, 3Hospital Clinico Universitario, Santiago de Compostela, Spain, 4Università Politecnica delle Marche, Ancona, Italy, 5Bristol-Myers Squibb, Rueil Malmaison, France, 6Docs International, Sèvres, France, 7Bristol-Myers Squibb, Princeton, NJ, 8UZ Gasthuisburg, Leuven, Belgium

Improvement in Disease Activity and Treatment Response Over 2 Years of Abatacept Treatment and Shifts to Improved Disease States in Patients with Early RA Who Switch From MTX
Rene Westhovens1, Juan J. Gomez-Reino2, Walter Grassi3, Corine Gaillez4, Manuela Le Bars4, Coralie Poncet5, Ayanbola Elegbe6 and Jurgen Wollenhaupt7, 1UZ Gasthuisburg, Leuven, Belgium, 2Hospital Clinico Universitario, Santiago de Compostela, Spain, 3Università Politecnica delle Marche, Ancona, Italy, 4Bristol-Myers Squibb, Rueil Malmaison, France, 5Docs International, Sèvres, France, 6Bristol-Myers Squibb, Princeton, NJ, 7Schön-Klinik Hamburg-Eilbeck, Hamburg, Germany

Characterization of Long-Term Responders to First Treatment Course of Rituximab (RTX) – Results From the CERERRA Collaboration
Elisabeth Lie1, Katerina Chatzidionysiou2, Evgeny L. Nasonov3, Galina Lukina3, Karel Pavelka4, Dan C. Nordström5, Matija Tomsic6, Cem Gabay7, Ioan Ancuta8, Piet LC van Riel9, Juan J. Gomez-Reino10, João E. Fonseca11, Merete L. Hetland12, Ulrik Tarp13, Tore K. Kvien1 and Ronald F. van Vollenhoven2, 1Diakonhjemmet Hospital, Oslo, Norway, 2Karolinska Institute, Stockholm, Sweden, 3Institute of Rheumatology, Moscow, Russia, 41Institute of Rheumatology, Department of Experimental Rheumatology, 1st Faculty of Medicine, Charles University in Prague, Prague, Czech Republic, 5ROB-FIN, Helsinki University Central Hospital, Helsinki, Finland, 6University Medical Centre Ljubjana, Ljubljana, Slovenia, 7University Hospitals of Geneva, on behalf of the SCQM registry, Geneva, Switzerland, 8Cantacuzino Hospital, Bucharest, Romania, 9Radboud University Nijmegen Medical Centre, Nijmegen, Netherlands, 10Hospital Clinico Universitario, Santiago, Spain, 11Lisbon Academic Medical Center, on behalf of Rheumatic Diseases Portuguese Register (Reuma.pt), Lisbon, Portugal, 12Copenhagen University Hospital at Glostrup, on behalf of DANBIO, Copenhagen, Denmark, 13Aarhus University Hospital, Aarhus, Denmark
Hospital Clinico Universitario de Santiago
Influence of Baseline Rheumatoid Factor on the Response to Tumor Necrosis Factor Antagonists of Rheumatoid Arthritis Patients: A Systematic Review and Meta-Analysis
Eva Salgado, Jose Ramon Maneiro, Loreto Carmona and Juan J. Gomez-Reino, Hospital Clinico Universitario de Santiago, Santiago de Compostela, Spain
Hospital Cochin
Less-Experienced Rheumatologists Can Improve Agreement in the Detection of Clinical Synovitis Through Consensus in Rheumatoid Arthritis (RA)
Peter Cheung1, Vincent Andre2, Natalie Balandraud3, Gerard H. Chales4, Isabelle Chary-Valckaneare5, Emmanuel Chatelus6, Emmanuelle Dernis2, Ghislaine Gill5, Melanie Gilson7, Sandrine Guis3, Thierry Marhadour8, Gael Mouterde9, Stephan Pavy10, Francois Pouyol11, Pascal Richette12, Adeline Ruyssen-Witrand13, Martin Soubrier14, Maxime Dougados15 and Laure Gossec16, 1Hospital Cochin, Paris, France, 2Centre Hospitalier, Le Mans, France, 3Hopital de la Conception, Marseilles, France, 4CHR - Hopital Sud, Rennes, France, 5Hopital de Brabois, Nancy, France, 6Hopital Hautepierre, Strasbourg, France, 7CH Grenoble Hopital Sud, Grenoble, France, 8CHU La Cavale Blanche, Brest, France, 9Hopital Lapeyronie, Montpellier, France, 10Hopital Bicetre, Paris, France, 11Hopital de Roger Salengro, Lille, France, 12Lariboisière Hospital, Paris, France, 13Hopitaux de Toulouse, Toulouse, France, 14CHU CLERMONT-FERRAND, Clermont-Ferrand, France, 15Paris-Descartes University, Cochin Hospital, Paris, France, 16Cochin Hospital, Paris, France

Does Clinical Assessment of Swollen and Tender Joints Reflect Inflammatory Synovitis in Rheumatoid Arthritis? A Comparative Study of Physician, Nurse and Patient Clinical Assessments Versus Ultrasonography (US) As the Gold Standard
Peter Cheung1, Laure Gossec2, Adeline Ruyssen-Witrand3, Catherine Le Bourlout4, Maryse Mezieres4 and Maxime Dougados5, 1National University Hospital, Singapore, Singapore, 2Cochin Hospital, Paris, France, 3Hopitaux de Toulouse, Toulouse, France, 4Hospital Cochin, Paris, France, 5Paris-Descartes University, Cochin Hospital, Paris, France
Hospital Cullen
Prevalence and Correlates of Metabolic Syndrome in Patients with Rheumatoid Arthritis
Maria Haye Salinas1, Ana M. Bertoli2, Francisco Caeiro3, Luis Lema4, Veronica Bellomio5, Santiago Aguero6, Federico Ceccato7, Carla Saucedo8, Javier Rosa8, R. Quintana9, Marcela Schmid10, Walter Spindler11, Natalia Tamborenea12, Sergio Paira7, Bernardo Pons Estel13, Alberto J. Spindler14, Enrique R. Soriano8, Alejandro J. Alvarellos15 and Veronica Saurit16, 1Hospital Privado, Córdoba, Argentina, 2Instituto Reumatológico Strusberg, Cordoba, Cordoba, Argentina, 3Hospital Privado de Cordoba, Cordoba, Argentina, 4Instituto Modelo de Cardiologia, Cordoba, Argentina, 5Consultorio, Tucuman, Argentina, 6Centro de Rehabilitación II, Catamarca, Argentina, 7Hospital Jose Maria Cullen, Santa Fe, Argentina, 8Rheumatology Unit, Internal Medical Services, Hospital Italiano de Buenos Aires, Buenos Aires, Argentina, 9Hospital Provincial, Rosario, Argentina, 10Hospital Cullen, Santa Fe, Argentina, 11Centro Medico Privado, Tucuman, Argentina, 12Consultorio, Buenos Aires, Argentina, 13Sanatorio Parque, Rosario, Argentina, 14Universidad Nacional Tucumán, Yerba Buena Tucuman, Argentina, 15Hospital Privado, Cordoba, Argentina, 16Hospital Privado Córdoba, Córdoba, Argentina
Hospital das Clínicas - Universidade Federal de Pernambuco
Vitamin D Deficiency in Patients with Systemic Lupus Erythematosus and Rheumatoid Artrhitis in a Tropical Country
Claudia D.L. Marques, Thiago Sotero Fragoso, Andrea Tavares Dantas, Aline Jurema G. Costa, Henrique A. Mariz, Aline Ranzolin and Angela Luzia B. P. Duarte, Hospital das Clínicas - Universidade Federal de Pernambuco, Recife - PE, Brazil

EpiFibro – A Brazilian Nationwide Databank in Fibromyalgia – Analysis of 500 Women
Roberto E. Heymann1, Eduardo S. Paiva2, Marcelo C. Rezende3, Daniel Feldman4, Milton Helfenstein Jr.1, Jose E. Martinez5, Jose R. Provenza6, Aline Ranzolin7, Luiz S. Ribeiro8 and Eduardo J.R. Souza9, 1Universidade Federal de São Paulo, São Paulo, Brazil, 2Universidade Federal do Parana, Curitiba, Brazil, 3Santa Casa de Campo Grande, Campo Grande, Brazil, 4Universidade Federal de São Paulo, Sao Paulo, Brazil, 5Pontifícia Universidade Católica de São Paulo, Sorocaba, Brazil, 6Pontifícia Universidade Católica de Campinas, Campinas, Brazil, 7Hospital das Clínicas - Universidade Federal de Pernambuco, Recife, Brazil, 8Instituto de Previdência dos Servidores do Estado de Minas Gerais, Belo Horizonte, Brazil, 9Santa Casa de Belo Horizonte, Belo Horizonte, Brazil

EpiFibro – A Brazilian Nationwide Databank in Fibromyalgia – 2010 Fibromyalgia Criteria, “Fibromyalgianess” Score and FIQ Performances
Eduardo S. Paiva Sr., Universidade Federal do Parana, Curitiba Parana, Brazil, Roberto E. Heymann, UNIFESP - UNIVERSIDADE FEDERAL DE SÃO PAULO, São Paulo, Brazil, Marcelo C. Rezende, Santa Casa de Campo Grande, Campo Grande, Brazil, Daniel Feldman, Universidade Federal de de São Paulo, Sao Paulo, Brazil, Milton Helfenstein Jr., Universidade Federal de de São Paulo, São Paulo, Brazil, Jose E. Martinez, Pontifícia Universidade Católica de São Paulo, Sorocaba, Brazil, Jose R. Provenza, Pontifícia Universidade Católica de Campinas, Campinas, Brazil, Aline Ranzolin, Hospital das Clínicas - Universidade Federal de Pernambuco, Recife, Brazil, Luiz S. Ribeiro, Instituto de Previdência dos Servidores do Estado de Minas Gerais, Belo Horizonte, Brazil and Eduardo J.R. Souza, Santa Casa de Belo Horizonte, Belo Horizonte, Brazil
Hospital das Clínicas, Faculdade de Medicina, Universidade de São Paulo
Abnormal Morphology and Excessive Synthesis of Collagen V Affects Skin Thickness and Disease Activity in Systemic Sclerosis
Patricia Martin1, Walcy R. Teodoro1, Ana Paula P. Velosa2, Jymenez de Morais1, Solange Carrasco3, Francine F. R. Braga1, Romy Christmann4, Claudia Goldenstein-Schainberg5, Edwin R. Parra1, Vera L. Capelozzi1 and Natalino H. Yoshinari2, 1Universidade de São Paulo, São Paulo, Brazil, 2Univerdidade de São Paulo, São Paulo, Brazil, 3Hospital das Clínicas, Faculdade de Medicina, Universidade de São Paulo, São Paulo, Brazil, 4Boston University, Boston, MA, 5University of São Paulo, São Paulo, Brazil
Hospital de Bellvitge
Changes in Psychological Status in Patients with Chronic Spondyloarthropathy Treated with Infliximab
Rosa M. Morlà1, Hector Corominas2, M. V. Hernandez3, Mireia Moreno4, Miquel Sala5, Vera Ortiz-Santamaria6, Patricia Reyner6, Vicente Torrente-Segarra Jr.7, Agusti Sellas Fernandez8, Georgina Salvador9, Elena Sirvent10, Cristina Masuet11 and Xavier Juanola-Roura12, 1Hospital Sta Tecla, Tarragona, Spain, 2Hospital Moises Broggi, Barcelona, 3Hospital Clinic of Barcelona, Barcelona, Spain, 4Servei de Reumatologia, Sabadell, Spain, 5Rheumatology Unit, Figueres, Spain, 6Unitat de Reumatologia, Spain, 7Hospital General de Hospitalet, Barcelona, Spain, 8Senior Consultant, Barcelon, Spain, 9Hospital Mutua de Terrassa. Barcelona, Barcelona, Spain, 10Hospital de Sant Boi, 11Hospital de Bellvitge, Hospitalet de LLobregat, Spain, 12Hospital Universitario de Bellvitge, Barcelona, Spain
Hospital de Clínicas de Porto Alegre
The Role of BsmI and FokI Vitamin D Receptor Gene Polymorphisms and Serum 25-Hydroxyvitamin D in Systemic Lupus Erythematosus
Odirlei A. Monticielo1, Jose A. B. Chies1, Guilherme G. Rucatti2, Maria G. F. Longo1, R. Scalco3, João Carlos T. Brenol1 and Ricardo M. Xavier1, 1Universidade Federal do Rio Grande do Sul, Porto Alegre, Brazil, 2Universidade Federal do Rio Grande do Sul, Porto A legre, Brazil, 3Hospital de Clínicas de Porto Alegre, Porto Alegre, Brazil
Hospital De Cruces
Validation of the Measurement of Tophi with Magnetic Resonance Imaging As An Outcome Measure for Chronic Gout
Fernando Perez-Ruiz, Hospital De Cruces, Baracaldo, Spain, Aranzazu Urresola, Radiology Division. Hospital de Cruces., Baracaldo, Spain, Diana Gorostiza, Radiology Division, Hospital de Cruces, Baracaldo, Spain and Begoña Canteli, Radiology Division. Hospital de Cruces, Baracaldo, Spain


Efficacy and SAFETY of Lesinurad (RDEA594), A NOVEL Uricosuric Agent, Given In COMBINATION with ALLOPURINOL In ALLOPURINOL-REFRACTORY Gout PATIENTS: PRELIMINARY RESULTS FROM the RANDOMIZED, DOUBLE-BLIND, PLACEBO-CONTROLLED, PHASE 2B Extension STUDY
John Sundy1, Fernando Perez-Ruiz2, Eswar Krishnan3, Vijay Hingorani4, Jody Welp4, Matt Suster4, Kimberly Manhard4, Matt Cravets4, David Hagerty4 and Barry Quart4, 1Duke University Medical Center, Durham, NC, 2Hospital De Cruces, Baracaldo, Spain, 3Stanford University, Stanford, CA, 4Ardea Biosciences, Inc., San Diego, CA
Hospital de Cruces
Biologics use in SLE in 23 Centers - Data from the International Registry for Biologics In SLE (IRBIS)
R.F. van Vollenhoven1, Søren Jacobsen2, Daniel Wallace3, John G. Hanly4, Michelle Petri5, David A. Isenberg6, Sasha Bernatsky7, Sang-Cheol Bae8, Manuel Ramos-Casals9, Guillermo Ruiz-Irastorza10, Francisco J. García-Hernández11, Luis Saez12, José Luis Callejas13, Javier Rascón14, Enrique de Ramón15, Mª Mar Ayala-Gutiérrez15, Maite Camps15, Melinda Mild16, Murat Inanç17, Bahar Artim-Esen17, Rosalind Ramsey-Goldman18, Christine A. Peschken19, Danilo Squatrito20, László Kovács21, Andrea Doria22, Zoltan Szekanecz23, Elisa Gremese24 and Emilia I. Sato25, 1Karolinska University Hospital, Stockholm, Sweden, 2Copenhagen University Hospital, Copenhagen, Denmark, 3Cedars-Sinai/UCLA, Los Angeles, CA, 4Dalhousie University and Capital Health, Halifax, NS, 5Johns Hopkins Hospital, Baltimore, MD, 6University College London, London, United Kingdom, 7McGill UHC/RVH, Montreal, QC, 8Hanyang University Hospital for Rheumatic Diseases, Seoul, South Korea, 9Hospital Clínic, Barcelona, Spain, 10Hospital de Cruces, Bizkaia, Spain, 11Hospital Virgen del Rocío, Sevilla, Spain, 12Hospital Miguel Servet, Zaragoza, Spain, 13Hospital San Cecilio, Granada, Spain, 14Hospital Son Dureta, Palma de Mallorca, Spain, 15Hospital Carlos Haya, Málaga, Spain, 16Karolinska Institutet, Stockholm, Sweden, 17Istanbul University, Istanbul Medical Faculty, Istanbul, Turkey, 18Northwestern University Feinberg School of Medicine, Chicago, IL, 19Univ of Manitoba, Winnipeg, MB, 20Careggi Hospital- Florence, Florence, Italy, 21University of Szeged, Szeged, Hungary, 22University of Padova, Padova, Italy, 23University of Debrecen Medical and Health Sciences Center, Debrecen, Hungary, 24Rheumatology Unit, Catholic University, Roma, Italy, 25Escola Paulista de Medicina - Universidade Federal de São Paulo, Sao Paulo, Brazil

Demographic and Genetic Results From the EUROFEVERS/EUROTRAPS Consortia in the Largest Series of Patients with TRAPS Yet Reported
Helen J. Lachmann1, Antonella Meini2, Isabelle Touitou3, Laura Obici4, Martina Finetti5, Kirsten Minden6, Luca Cantarini7, Marine Desjonqueres8, Joost Frenkel9, Isabelle Kone-Paut10, Olga Vougiouka11, Maria Jesus Rua Elorduy12, Nicola Ruperto13, Patricia Woo1 and Marco Gattorno14, 1University College London Medical School, London, United Kingdom, 2Dipartimento di Pediatria, University of Brescia, Brescia, Italy, 3CHU Montpellier - Hôpital Arnaud de Villeneuve, Montpellier, France, 4IRCCS Policlinico S. Matteo, Pavia, Italy, 5IRCCS Istituto G. Gaslini, Genova, Italy, 6Charite, Berlin, Germany, 7Policlinico le Scotte, Sienna, Italy, 8Hopital Femme Mere Enfant, Groupement Hospitalier Est, Lyon, France, 9University Medical Center Utrecht, Utrecht, Netherlands, 10CHU Le Kremlin Bicetre, Paris, France, 11P. A. Kyriakou Childrens Hospital of Athens University, Athens, Greece, 12Hospital de Cruces, Barakaldo, Spain, 13Paediatric Rheumatology International Trials Organisation – IRCCS [PRINTO], Genova, Italy, 14G Gaslini Institute, Genoa, Italy

High Dose Intravenous Methylprednisolone Induces Rapid Improvement In Severe Uveitis: A Multicenter Study
Carmen Bejerano1, Ricardo Blanco1, Emma Beltrán2, Alejandro Fonollosa3, Olga Maiz4, Ana Blanco-Esteban4, Miguel Cordero5, Inés Pérez-Martín6, Joaquín Cañal6, Juan Ventosa6 and Miguel Angel González-Gay6, 1Hospital Universitario Marqués de Valdecilla-IFIMAV, Santander, Spain, 2Hospital Peset, Valencia, Spain, 3Hospital de Cruces, Barakaldo-Bilbao, Spain, 4Hospital Donostia, San Sebastian, Spain, 5Hospital León, León, Spain, 6Hospital Universitario Marqués de Valdecilla. IFIMAV, Santander, Spain

Adalimumab in 107 Refractory Uveitis: A Multicenter Study
Orlando Pompei1, Ricardo Blanco2, Manuel Diaz-llopis3, David Salom3, Carmen Garcia-Vicuña4, Miguel Cordero-Coma5, Gabriela Ortega-Larrocea6, Norberto Ortego-Centeno7, Marta Suarez-de-Figueroa8, J. Carlos Fernandez-Cid9, Alejandro Fonollosa10, Angel M. Garcia-Aparicio11, Jose M. Benítez-del-Castillo12, Jose L. Olea13 and J. Fernando Arevalo14, 1Hospital Universitario Marqués de Valdecilla. IFIMAV, Santander, Spain, 2Hospital Universitario Marqués de Valdecilla-IFIMAV, Santander, Spain, 3La Fe University Hospital of Valencia, Valencia, Spain, 4Hospital Sant Joan de Déu, Barcelona, Spain, 5Hospital de León, León, Spain, 6National Institute of Rehabilitation, D.F Mexico, Mexico, 7Hospital Clínico San Cecilio, Granada, Spain, 8Hospital Ramon y Cajal, Madrid, Spain, 9Hospital de Pontevedra, Pontevedra, Spain, 10Hospital de Cruces, Bilbao, Spain, 11Hospital Virgen de la Salud, Toledo, Spain, 12Hospital Clínico San Carlos, Madrid, 13Hospital Son Dureta, Palma de Mallorca, Spain, 14Ophthalmology Clinic Center of Caracas, Caracas, Venezuela
Hospital de Cruces, UPV/EHU
Peripheral Arterial Disease in Systemic Lupus Erythematosus
Jose-Gabriel Erdozain1, Irama Villar2, Javier Nieto2, María-Victoria Egurbide2 and Guillermo Ruiz-Irastorza2, 1Hospital de Mendaro, Mendaro, Spain, 2Hospital de Cruces, UPV/EHU, Barakaldo, Spain
Hospital de Cruces, UPV/EHU, Barakaldo, Spain
The IRF7 Region Is Associated with Anti-Centromere Autoantibody Production in Systemic Sclerosis Patients
F. David Carmona1, Ramana Gutala2, Carmen P. Simeón3, Patricia E. Carreira4, Norberto Ortego-Centeno5, Esther Vicente-Rabaneda6, Francisco J. García-Hernández7, Paloma García de la Peña8, Mónica Fernández-Castro9, Lina Martínez-Estupiñán10, María-Victoria Egurbide11, Spanish Scleroderma Group, Betty P. Tsao13, Pravitt R. Gourh14, Sandeep K. Agarwal15, Shervin Assassi16, Maureen D. Mayes15, Frank C. Arnett15, Filemon K. Tan15 and Javier Martín17, 1Consejo Superior de Investigaciones Científicas, Armilla (Granada), Spain, 2The University of Texas Health Science Center, Houston, TX, 3Hospital Valle de Hebron, Barcelona, Spain, 4Instituto de Investigación Hospital 12 de Octubre (I+12), Madrid, Spain, 5Hospital Clínico San Cecilio, Granada, Spain, 6Hospital de la Princesa, Madrid, Spain, 7Hospital Virgen del Rocío, Sevilla, Spain, 8Hospital Universitario Madrid Norte Sanchinarro, Madrid, Spain, 9Hospital Puerta de Hierro, Madrid, Spain, 10Gregorio Marañón Hospital, Madrid, Spain, 11Hospital de Cruces, UPV/EHU, Barakaldo, Spain, Barakaldo, Spain, 12David Geffen School of Medicine University of California Los Angeles, Los Angeles, CA, 13UTHSC-Houston Medical School, Houston, TX, 14University of Texas Health Science Center at Houston, Houston, TX, 15Univ of Texas Health Science, Houston, TX, 16Consejo Superior de Investigaciones Científicas, Granada, Spain
Hospital de Curry Cabral
Off-Label Use of Biological Therapies in Systemic Autoimmune Diseases
Ana Carolina Araújo, Carla Noronha, Ana Grilo, Maria Francisca Moraes-Fontes, Nuno Riso and Manuel Vaz Riscado, Hospital de Curry Cabral, Lisbon, Portugal
Hospital de Especialidades Centro Médico La Raza, IMSS
Development and Initial Validation of a chronic Damage Index in Patients with Antiphospholipid Syndrome
Mary-Carmen Amigo, ABC Medical Ctr, Mexico City, Mexico, Leonor A. Barile, Hospital Especialidades CMN, Mexico City, Mexico, Alberto Barragan, México, Mexico, Gisela Espinosa-Cuervo, Research Unit, Mexican College of Rheumatology, Mexico, Mexico, Mavis Goycochea, Instituto Mexicano del Seguro Social and Research Unit, Mexican College of Rheumatology, Mexico City, Mexico, Laura Aline Martinez-Martinez, Intituto Nacional de Cardiologia, Mexico, Mexico, Gabriela Medina, Seris/Zachila s/n La Raza, Mexico City, Mexico, Angelica Vargas, Instituto Nac de Cardiologia, Mexico City, Mexico and Luis J. Jara-Quezada, Hospital de Especialidades Centro Médico La Raza, IMSS, Mexico City, Mexico

Myocardial Global Longitudinal Strain in Primary Antiphospholipid Syndrome
Gabriela Medina, Eduardo Gómez-Bañuelos, Erick Calderón-Aranda and Luis J. Jara, Hospital de Especialidades Centro Médico La Raza, IMSS, Mexico City, Mexico
Hospital de Especialidades CMN La Raza, IMSS
SELF-Administered Systemic Sclerosis Questionnaire. Validation of A SPANISH Version (SYSQ) In Mexicans
Maria Pilar Cruz-Dominguez1, Moises Casarrubias-Ramirez1, Victor Gasca Martínez1, Olga Lidia Vera Lastra1, Luis J. Jara Quezada2 and Daniel Hector Montes-Cortes3, 1Hospital de Especialidades CMN La Raza, IMSS, Mexico, DF, Mexico, 2Hospital de Especialidades CMN La Raza, IMSS, Mexico City, Mexico, 3Hospital General CMN La Raza, IMSS, Mexico DF, Mexico
Hospital de Especialidades Miguel Hidalgo, Aguascalientes
The Protective Effect of Antimalarials On Thrombovascular Events In Latin American Systemic Lupus Erythematosus Patients
Guillermo J. Pons-Estel, Servicio de Enfermedades Autoinmunes, Hospital Clìnic Barcelona, Barcelona, Spain, Graciela S. Alarcón, University of Alabama at Birmingham, Birmingham, AL, Daniel Wojdyla, Universidad Nacional de Rosario, Argentina, Rosario, Argentina, Ana I. Marcos, Hospital Interzonal General de Agudos “General San Martin, La Plata, La Plata, Argentina, Alejandro J. Alvarellos, Hospital Privado, Cordoba, Argentina, Antonio A. Iglesias-Gamarra, Universidad Nacional, Bogota, Colombia, Maria H. Esteva-Spinetti, Centro Clinico San Cristobal, San Cristobal, Venezuela, Lilian Costallat, Faculdade de Ciencias Medicas, Universidade Estadual de Campinas, Campinas, Brazil, Nilzio A. Silva, Faculdade de Medicina, Universidade Federal de Goias, Goiania, Brazil, Gloria Vázquez, Universidad de Antioquia, Hospital Universitario “San Vicente de Paul”, Medellín, Colombia, Maria Loreto Massardo, Catholic University of Chile, Santiago, Chile, Marlene Guibert-Toledano, Centro de Investigaciones Médico Quirúrgicas, Habana, La Habana, Cuba, Guillermo F. Huerta-Yáñez, Hospital de Especialidades Miguel Hidalgo, Aguascalientes, Mexico, Mariano Cucho-Venegas, Almenara Hospital IPSs, Lima, Peru and Bernardo Pons-Estel, Hospital Provincial de Rosario, Rosario, Argentina
Hospital de G C Dr Negrin
Emperipolesis and Cell Death in NOD2-Related Blau Syndrome and Crohn's Disease   
Carl EI Janssen1, Carlos D. Rose2, A. Naranjo3, Brigitte Bader-Meunier4, Rolando Cimaz5, Miroslav Harjacek6, Pierre Quartier7, Rebecca Ten Cate8, Caroline Thomée9, Isabelle Cleynen1, Tammy M. Martin10, Gert De Hertogh1, Tania Roskams1, Valeer J. Desmet1 and Carine H. Wouters11, 1University Hospital Leuven, Leuven, Belgium, 2duPont Hospital for Children, Wilmington, DE, 3Hospital de G C Dr Negrin, Las Palmas GC, Spain, 4Hôpital Necker, Paris, France, 5Anna Meyer Children's Hospital, Florence, Italy, 6Zagreb, 7IRCCS G. Gaslini, Pediatria II, PRINTO, Paediatric Rheumatology, Genova, Italy, 8PO Box 9600, Leiden, Netherlands, 9Centre Hospitalier, Luxembourg, Luxembourg, 10Oregon Health & Science Univ, Portland, OR, 11Paediatric Rheumatology Internationsl Trials Organization, Leuven, Belgium
Hospital de GC Dr Negrin
Mortality Causes and Associated Factors in a Systemic Lupus Erythematosus Monocentric Cohort: Is the Systolic Pulmonary Artery Pressure  a Risk Factor for Death?
I. Rua-Figueroa, C. Erausquin, MD Fiuza, F. Francisco-Hernández, S. Ojeda, A. Naranjo, JC Quevedo, A. Acosta, R. Lopez -R and C. Rodriguez-Lozano, Hospital de GC Dr Negrin, Las Palmas GC, Spain
Hospital de la Princesa
The IRF7 Region Is Associated with Anti-Centromere Autoantibody Production in Systemic Sclerosis Patients
F. David Carmona1, Ramana Gutala2, Carmen P. Simeón3, Patricia E. Carreira4, Norberto Ortego-Centeno5, Esther Vicente-Rabaneda6, Francisco J. García-Hernández7, Paloma García de la Peña8, Mónica Fernández-Castro9, Lina Martínez-Estupiñán10, María-Victoria Egurbide11, Spanish Scleroderma Group, Betty P. Tsao13, Pravitt R. Gourh14, Sandeep K. Agarwal15, Shervin Assassi16, Maureen D. Mayes15, Frank C. Arnett15, Filemon K. Tan15 and Javier Martín17, 1Consejo Superior de Investigaciones Científicas, Armilla (Granada), Spain, 2The University of Texas Health Science Center, Houston, TX, 3Hospital Valle de Hebron, Barcelona, Spain, 4Instituto de Investigación Hospital 12 de Octubre (I+12), Madrid, Spain, 5Hospital Clínico San Cecilio, Granada, Spain, 6Hospital de la Princesa, Madrid, Spain, 7Hospital Virgen del Rocío, Sevilla, Spain, 8Hospital Universitario Madrid Norte Sanchinarro, Madrid, Spain, 9Hospital Puerta de Hierro, Madrid, Spain, 10Gregorio Marañón Hospital, Madrid, Spain, 11Hospital de Cruces, UPV/EHU, Barakaldo, Spain, Barakaldo, Spain, 12David Geffen School of Medicine University of California Los Angeles, Los Angeles, CA, 13UTHSC-Houston Medical School, Houston, TX, 14University of Texas Health Science Center at Houston, Houston, TX, 15Univ of Texas Health Science, Houston, TX, 16Consejo Superior de Investigaciones Científicas, Granada, Spain
Hospital de León
Adalimumab in 107 Refractory Uveitis: A Multicenter Study
Orlando Pompei1, Ricardo Blanco2, Manuel Diaz-llopis3, David Salom3, Carmen Garcia-Vicuña4, Miguel Cordero-Coma5, Gabriela Ortega-Larrocea6, Norberto Ortego-Centeno7, Marta Suarez-de-Figueroa8, J. Carlos Fernandez-Cid9, Alejandro Fonollosa10, Angel M. Garcia-Aparicio11, Jose M. Benítez-del-Castillo12, Jose L. Olea13 and J. Fernando Arevalo14, 1Hospital Universitario Marqués de Valdecilla. IFIMAV, Santander, Spain, 2Hospital Universitario Marqués de Valdecilla-IFIMAV, Santander, Spain, 3La Fe University Hospital of Valencia, Valencia, Spain, 4Hospital Sant Joan de Déu, Barcelona, Spain, 5Hospital de León, León, Spain, 6National Institute of Rehabilitation, D.F Mexico, Mexico, 7Hospital Clínico San Cecilio, Granada, Spain, 8Hospital Ramon y Cajal, Madrid, Spain, 9Hospital de Pontevedra, Pontevedra, Spain, 10Hospital de Cruces, Bilbao, Spain, 11Hospital Virgen de la Salud, Toledo, Spain, 12Hospital Clínico San Carlos, Madrid, 13Hospital Son Dureta, Palma de Mallorca, Spain, 14Ophthalmology Clinic Center of Caracas, Caracas, Venezuela
Hospital de Mendaro
Peripheral Arterial Disease in Systemic Lupus Erythematosus
Jose-Gabriel Erdozain1, Irama Villar2, Javier Nieto2, María-Victoria Egurbide2 and Guillermo Ruiz-Irastorza2, 1Hospital de Mendaro, Mendaro, Spain, 2Hospital de Cruces, UPV/EHU, Barakaldo, Spain
Hospital de Pediatría Pedro de Elizalde
Defining Clinical Remission and Inactive Disease in Juvenile Systemic Lupus Erythematosus
Rina Mina, Cincinnati Children's Med Ctr, Cincinnati, OH, Laura E. Schanberg, Duke University Medical Center, Durham, NC, Marisa Klein-Gitelman, Children's Memorial Hospital, Chicago, IL, B. Anne Eberhard, Cohen Children's Hospital Medical Center, New Hyde Park, NY, Gloria Higgins, PRCSG, Columbus, OH, Karen Onel, University of Chicago, Chicago, IL, Nora G. Singer, MetroHealth Medical Center, Cleveland, OH, Kathleen M. O'Neil, Okla Univ Health Science Ctr, Oklahoma City, OK, Deborah M. Levy, The Hospital for Sick Children, Toronto, ON, Shannen L. Nelson, Cincinnati Children's Hospital, Cincinnati, OH, Wajeeha Yousaf, University of Cincinnati, Rubén J. Cuttica, Hospital de Pediatría Pedro de Elizalde, Buenos Aires, Argentina, Lori B. Tucker, BC Childrens Hospital, Vancouver, BC, Michael W. Beresford, Alder Hey Children's NHS Foundation Trust, Liverpool, United Kingdom, Graciela Espada, Childrens Hosp Ricardo Gutierrez, Buenos Aires, Argentina, Angelo Ravelli, Istituto di Ricovero e Cura a Carattere Scientifico G. Gaslini, Genova, Italy, Alberto Martini, IRCCS G Gaslini, Pediatria II, Reumatologia, Genova, Italy, Edward H. Giannini, PRCSG-Cincinnati Children's Hospital Medical Center, Cincinnati, OH and Hermine Brunner, Cincinnati Children's Hospital Medical Center, Cincinnati, OH
Hospital de Pontevedra
Adalimumab in 107 Refractory Uveitis: A Multicenter Study
Orlando Pompei1, Ricardo Blanco2, Manuel Diaz-llopis3, David Salom3, Carmen Garcia-Vicuña4, Miguel Cordero-Coma5, Gabriela Ortega-Larrocea6, Norberto Ortego-Centeno7, Marta Suarez-de-Figueroa8, J. Carlos Fernandez-Cid9, Alejandro Fonollosa10, Angel M. Garcia-Aparicio11, Jose M. Benítez-del-Castillo12, Jose L. Olea13 and J. Fernando Arevalo14, 1Hospital Universitario Marqués de Valdecilla. IFIMAV, Santander, Spain, 2Hospital Universitario Marqués de Valdecilla-IFIMAV, Santander, Spain, 3La Fe University Hospital of Valencia, Valencia, Spain, 4Hospital Sant Joan de Déu, Barcelona, Spain, 5Hospital de León, León, Spain, 6National Institute of Rehabilitation, D.F Mexico, Mexico, 7Hospital Clínico San Cecilio, Granada, Spain, 8Hospital Ramon y Cajal, Madrid, Spain, 9Hospital de Pontevedra, Pontevedra, Spain, 10Hospital de Cruces, Bilbao, Spain, 11Hospital Virgen de la Salud, Toledo, Spain, 12Hospital Clínico San Carlos, Madrid, 13Hospital Son Dureta, Palma de Mallorca, Spain, 14Ophthalmology Clinic Center of Caracas, Caracas, Venezuela
Hospital de Sant Boi
Changes in Psychological Status in Patients with Chronic Spondyloarthropathy Treated with Infliximab
Rosa M. Morlà1, Hector Corominas2, M. V. Hernandez3, Mireia Moreno4, Miquel Sala5, Vera Ortiz-Santamaria6, Patricia Reyner6, Vicente Torrente-Segarra Jr.7, Agusti Sellas Fernandez8, Georgina Salvador9, Elena Sirvent10, Cristina Masuet11 and Xavier Juanola-Roura12, 1Hospital Sta Tecla, Tarragona, Spain, 2Hospital Moises Broggi, Barcelona, 3Hospital Clinic of Barcelona, Barcelona, Spain, 4Servei de Reumatologia, Sabadell, Spain, 5Rheumatology Unit, Figueres, Spain, 6Unitat de Reumatologia, Spain, 7Hospital General de Hospitalet, Barcelona, Spain, 8Senior Consultant, Barcelon, Spain, 9Hospital Mutua de Terrassa. Barcelona, Barcelona, Spain, 10Hospital de Sant Boi, 11Hospital de Bellvitge, Hospitalet de LLobregat, Spain, 12Hospital Universitario de Bellvitge, Barcelona, Spain
Hospital de Santa Maria
Apolipoprotein E and Undercarboxylated Osteocalcin Are Associated with Bone Fragility but Not with Bone Mineral Density in Osteoarthritis Patients
Ana M. Rodrigues1, Joana Caetano-Lopes2, Ana Lopes3, Ana Catarina Vale4, Inês Aleixo3, Inês P. Perpétuo2, Ana Sofia Pena3, Alexandra Faustino3, Alexandre Sepriano3, Joaquim Polido-Pereira5, Elsa Vieira-Sousa6, Bruno Vidal7, JC Romeu8, PM Amaral4, Luis G. Rosa4, José A. Pereira da Silva9, Jacinto Monteiro10, Maria Fátima Vaz4, J. E. Fonseca5 and Helena Canhão5, 1Rheumatology Research Unit, Instituto de Medicina Molecular, Faculdade de Medicina da Universidade de Lisboa and Rheumatology Department, Centro Hospitalar de Lisboa Norte, EPE, Hospital de Santa Maria, Lisbon, Portugal, 2Rheumatology Research Unit, Faculdade de Medicina da Universidade de Lisboa, Lisbon, Portugal, 3Rheumatology Research Unit, Instituto de Medicina Molecular, Faculdade de Medicina da Universidade de Lisboa, Lisbon, Portugal, 4Department of Mechanical Engineering, Instituto Superior Técnico, ICEMS, Lisbon, Portugal, 5Instituto de Medicina Molecular, Faculdade de Medicina da Universidade de Lisboa and Rheumatology Department, Centro Hospitalar de Lisboa Norte, EPE, Hospital de Santa Maria, Lisboa, Portugal, 6Instituto de Medicina Molecular, Faculdade de Medicina da Universidade de Lisboa, Lisbon, Portugal, 7Instituto de Medicina Molecular, Faculdade de Medicina da Universidade de Lisboa, Lisbon, Portugal., Lisbon, Portugal, 8Hospital de Santa Maria, Lisbon, Portugal, 9Rheumatology Department, Centro Hospitalar de Lisboa Norte, EPE, Hospital de Santa Maria, Lisbon, Portugal, 10Orthopaedics Department, Hospital de Santa Maria, Lisbon, Portugal
Hospital del Mar-IMIM, Universitat Autònoma de Barcelona, Barcelona; and RETICEF, ISCIII Madrid; Spain
Osteoarthritis Is Related to An Increased Risk of Falls and Fractures: A Prospective Multinational Cohort Study (the GLOW study)
Daniel Prieto-Alhambra1, Xavier Nogués2, M. Kassim Javaid3, Nigel K. Arden3, Cyrus Cooper4, Allison Wyman5, Adolfo Díez-Pérez6 and GLOW Investigators, 1URFOA-IMIM, Parc de Salut Mar; Idiap Jordi Gol i Gurina-Institut Català de la Salut; Oxford NIHR Musculoskeletal Biomedical Research Unit, University of Oxford, Oxford, UK, Barcelona, Spain, 2Hospital del Mar-IMIM, Universitat Autònoma de Barcelona, Barcelona; and RETICEF, ISCIII Madrid; Spain, Barcelona, United Kingdom, 3Oxford NIHR Musculoskeletal Biomedical Research Unit, University of Oxford, Oxford, UK, Oxford, United Kingdom, 4Southampton General Hospital, Southampton, United Kingdom, 5Center for Outcomes Research, UMass Medical School, Worcester, MA, 6Hospital del Mar-IMIM, Universitat Autònoma de Barcelona, Barcelona; and RETICEF, ISCIII Madrid; Spain, Barcelona, Spain
Hospital do Meixoeiro
The Lupus Damage Index Questionnaire and Its Correlation with the SLICC/ACR Damage Index and the LupusQoL in a Spanish Multicenter Lupus Cohort. Is It Really Measuring Damage?
José M. Pego-Reigosa1, Íñigo Rúa-Figueroa2, Teresa Otón-Sánchez1, Manuela Fontanillo-Fontanillo1, María Galindo-Izquierdo3, Esther Uriarte-Isacelaya4, Bruno Aspe-de la Iglesia5, Laura Cáceres-Martín2 and Félix Francisco-Hernández2, 1Hospital do Meixoeiro, Vigo, Spain, 2Hospital Universitario Dr Negrín, Las Palmas de Gran Canaria, Spain, 3Hospital 12 de octubre, Madrid, Spain, 4Donosti, Spain, 5Vigo, Spain
Hospital Donostia
High Dose Intravenous Methylprednisolone Induces Rapid Improvement In Severe Uveitis: A Multicenter Study
Carmen Bejerano1, Ricardo Blanco1, Emma Beltrán2, Alejandro Fonollosa3, Olga Maiz4, Ana Blanco-Esteban4, Miguel Cordero5, Inés Pérez-Martín6, Joaquín Cañal6, Juan Ventosa6 and Miguel Angel González-Gay6, 1Hospital Universitario Marqués de Valdecilla-IFIMAV, Santander, Spain, 2Hospital Peset, Valencia, Spain, 3Hospital de Cruces, Barakaldo-Bilbao, Spain, 4Hospital Donostia, San Sebastian, Spain, 5Hospital León, León, Spain, 6Hospital Universitario Marqués de Valdecilla. IFIMAV, Santander, Spain
Hospital Especialidades CMN
Development and Initial Validation of a chronic Damage Index in Patients with Antiphospholipid Syndrome
Mary-Carmen Amigo, ABC Medical Ctr, Mexico City, Mexico, Leonor A. Barile, Hospital Especialidades CMN, Mexico City, Mexico, Alberto Barragan, México, Mexico, Gisela Espinosa-Cuervo, Research Unit, Mexican College of Rheumatology, Mexico, Mexico, Mavis Goycochea, Instituto Mexicano del Seguro Social and Research Unit, Mexican College of Rheumatology, Mexico City, Mexico, Laura Aline Martinez-Martinez, Intituto Nacional de Cardiologia, Mexico, Mexico, Gabriela Medina, Seris/Zachila s/n La Raza, Mexico City, Mexico, Angelica Vargas, Instituto Nac de Cardiologia, Mexico City, Mexico and Luis J. Jara-Quezada, Hospital de Especialidades Centro Médico La Raza, IMSS, Mexico City, Mexico
Hospital FACH
Clinical and Genetic Features of Autoinflammatory Syndromes in Hispanic Patients: The Chilean Experience
Cristian Vergara1, Arturo Borzutzky1, Miguel A. Gutierrez1, Sergio Iacobelli1, Eduardo Talesnik1, Maria Eugenia Martinez1, Lilith Stange1, Javier Basualdo2, Viviana Maluje3, Renato Jimenez4, Elena Jarpa5, Roberto Wiener6, Javier Tinoco6, Juan I. Arostegui7, Jordi Yague7 and Manuel Alvarez-Lobos1, 1Pontificia Universidad Catolica de Chile, Santiago, Chile, 2Universidad de Chile, Santiago, Chile, 3Hospital FACH, Santiago, Chile, 4Hospital Gustavo Fricke, Valparaiso, Chile, 5Hospital Naval Almirante Nef, Vina Del Mar, Chile, 6Hospital Militar, Santiago, Chile, 7Hospital Clínic / IDIBAPS, Barcelona, Spain
Hospital for Joint Disease
Activation of Adenosine A2A Receptors Prevents Wear Particle-Induced Osteolysis
Aranzazu Mediero1, Sally Frenkel2, Tuere Wilder1 and Bruce N. Cronstein3, 1NYU School of Medicine, New York, NY, 2Hospital for Joint Disease, New York, NY, 3New York Univ Medical Center, New York, NY
Hospital for Joint Diseases
Ferritin and Hemochromatosis Polymorphisms Correlate with Clinical Characteristics in a Symptomatic Osteoarthritis Cohort
Lauren M. Kennish1, Mukundan Attur2, Xi Huang3, Svetlana Krasnokutsky4, Jonathan Samuels2, Cheongeun Oh5 and Steven B. Abramson2, 1Hospital for Joint Diseases, New York, NY, 2NYU Hospital for Joint Diseases, New York, NY, 3New York University School of Medicine, New York, NY, 4NYU Hospital for Joint Disease, New York, NY, 5New York University, New York, NY

2010 American College of Rheumatology/European League Against Rheumatism Rheumatoid Arthritis Criteria Classifies 67% of Systemic Lupus Erythematosus and 38% of Psoriatic Arthritis As Rheumatoid Arthritis: Implications for Real World Use
Lauren M. Kennish1, Monalyn Labitigan2, Sam Budoff3, Maria T. Filopoulos1 and Yusuf Yazici4, 1Hospital for Joint Diseases, New York, NY, 2New York University, New York, NY, 3Vanderbilt University, Nashville, TN, 4Division of Rheumatology, New York University School of Medicine and NYU Hospital for Joint Diseases, New York, NY

Difference of Manifestations and Treatment Among Behcet's Syndrome Patients in the United States and Japan
Yuri Ohara1, Mitsumasa Kishimoto1, Tatsuo Kobayashi2, Christopher Swearingen3, M.T. Filopoulos4, Yasuharu Tokuda5, Hideto Oshikawa2, Kazuki Yoshida2, Masako Utsunomiya2, Makiko Kimura2, Masato Okada1, Kazuo Matsui2 and Yusuf Yazici6, 1St. Luke's International Hospital, Tokyo, Japan, 2Kameda Medical Center, Kamogawa City, Japan, 3University of Arkansas for Medical Sciences, Little Rock, AR, 4Hospital for Joint Diseases, New York, NY, 5University of Tsukuba, Ibaraki, Japan, 6Division of Rheumatology, New York University School of Medicine and NYU Hospital for Joint Diseases, New York, NY
Hospital For Sick Children
Whole Body Magnetic Resonance Imaging in Juvenile Spondyloarthritis:  Will It Provide Vital Information Compared to Clinical Exam Alone?
Alisa C. Rachlis1, Paul S. Babyn2, Edrise Lobo-Mueller3, Susanne M. Benseler1, Jennifer Stimec4, Michelle Anderson1, Margaret Reaume1, Kristi J. Whitney-Mahoney1, JoAnne Marcuz1 and Shirley Tse1, 1The Hospital for Sick Children, Toronto, ON, 2Saskatoon Health Region, Saskatoon, SK, 3Hospital for Sick Children, Toronto, ON, 4Hospital For Sick Children, Toronto, ON
Hospital for Sick Children
Use of Intra–Articular Steroid Injection in a Large Cohort of Children with Oligoarticular Juvenile Idiopathic Arthritis - the ReACCh Out Study
Julie Barsalou, Montreal Children's Hospital, McGill University, Montreal, QC, Ronald M. Laxer, The Hospital for Sick Children, Toronto, ON, Lori B. Tucker, BC Childrens Hospital, Vancouver, BC, Rae SM Yeung, Hospital for Sick Children, Toronto, ON, Kiem Oen, University of Manitoba, Winnipeg, MB, Ciaran M. Duffy, Children's Hospital of Eastern Ontario, Ottawa, ON and ReACCh Out Study Group, Ottawa

Whole Body Magnetic Resonance Imaging in Juvenile Spondyloarthritis:  Will It Provide Vital Information Compared to Clinical Exam Alone?
Alisa C. Rachlis1, Paul S. Babyn2, Edrise Lobo-Mueller3, Susanne M. Benseler1, Jennifer Stimec4, Michelle Anderson1, Margaret Reaume1, Kristi J. Whitney-Mahoney1, JoAnne Marcuz1 and Shirley Tse1, 1The Hospital for Sick Children, Toronto, ON, 2Saskatoon Health Region, Saskatoon, SK, 3Hospital for Sick Children, Toronto, ON, 4Hospital For Sick Children, Toronto, ON

Characterization of Active Joint Count Trajectories in Juvenile Idiopathic Arthritis
Roberta A. Berard, Children's Hospital of Western Ontario, London, ON, George A. Tomlinson, University of Toronto, Toronto, ON, Xiuying Li, University Health Network, Toronto, ON, Kiem Oen, University of Manitoba, Winnipeg, MB, Alan M. Rosenberg, Royal University Hospital, Saskatoon, SK, Brian M. Feldman, The Hospital for Sick Children, Toronto, ON, Rae SM Yeung, Hospital for Sick Children, Toronto, ON and Claire Bombardier, Institute for Work & Health, Toronto, ON

Comparison of CNS Vasculitis in Children and Adults: Is This the Same Disease Entity?
Marinka Twilt1, Tania Cellucci2, Carlo Salvarani3, Gene G. Hunder4 and Susanne M. Benseler1, 1The Hospital for Sick Children, Toronto, ON, 2Hospital for Sick Children, Toronto, ON, 3Arcispedale S Maria Nuova, Reggio Emilia, Italy, 4Mayo Clinic, Rochester, MN

A Secondary Analysis of the Atherosclerosis Prevention in Pediatric Lupus Erythematosus (APPLE) Study Shows That Atorvastatin Therapy Reduces Progression of Carotid Intima Medial Thickening in Pubertal SLE Patients with Higher C Reactive Protein
Stacy P. Ardoin1, Laura E. Schanberg2, Christy I. Sandborg3, Huiman Barnhart4, Eric Yow4, Greg Evans5, Kelly Mieszkalski2, Norman T. Ilowite6, Emily von Scheven7, B. Anne Eberhard8, Lisa F. Imundo9, Deborah M. Levy10, Yuki Kimura11, Earl D. Silverman12, Suzanne L. Bowyer13, Marilynn G. Punaro14, Nora G. Singer15, David D. Sherry16, Deborah K. McCurdy17, Marisa Klein-Gitelman18, Carol A. Wallace19, Richard M. Silver20, Linda Wagner-Weiner21, Gloria Higgins22 and Hermine Brunner23, 1Ohio State University, Columbus, OH, 2Duke University Medical Center, Durham, NC, 3Stanford University, Palo Alto, CA, 4Duke Clinical Research Institute, Durham, NC, 5Winston-Salem, NC, 6Children's Hospital Montefiore, Bronx, NY, 7UC San Francisco, San Francisco, CA, 8Cohen Children's Hospital Medical Center, New Hyde Park, NY, 9Childrens Hospital of New York, Columbia University Medical Center, New York, NY, 10The Hospital for Sick Children, Toronto, ON, 11Pediatrics, Hackensack, NJ, 12Hospital for Sick Children, Toronto, ON, 13James Whitcomb Riley Hospital, Indianapolis, IN, 14Texas Scottish Rite Hospital, Dallas, TX, 15Director, Division of Rheumatology, MetroHealth Medical Center, Case Western Reserve University, Cleveland, OH, 16Children's Hospital of Philadelphia, Philadelphia, PA, 17Mattel Children's Hospital, University of California, Los Angeles, Los Angeles, CA, 18Children's Memorial Hospital, Chicago, IL, 19Childrens Hosp & Regional Med, Seattle, WA, 20MUSC, Charleston, SC, 21University of Chicago Hospital, Chicago, IL, 22NATIONWIDE CHILDRENS HOSPITAL, Columbus, OH, 23Cincinnati Children's Hospital Medical Center, Cincinnati, OH

Treatment Delay in Kawasaki Disease – the Role of Non-Traditional Risk Factors
Nadia Luca1, Joyce C. Y. Ching1, Cedric Manlhiot2, Brian W. McCrindle2 and Rae SM Yeung1, 1Hospital for Sick Children, Toronto, ON, 2The Hospital for Sick Children, Toronto, ON

Cytomegalovirus in Pediatric Systemic Lupus Erythematosus: Screening and Therapeutic Implications
Evelyn V. Rozenblyum, Deborah M. Levy, Elizabeth Harvey, Diane Hebert and Earl D. Silverman, Hospital for Sick Children, Toronto, ON

CD146+ Endothelial Progenitor Cell Number Increases Following 36 Months of Atorvastatin Therapy in Children and Adolescents with SLE: The Atherosclerosis Prevention in Pediatric Lupus Erythematosus (APPLE) Cohort
Stacy P. Ardoin1, Thomas Povsic2, Laura E. Schanberg3, Christy I. Sandborg4, Huiman Barnhart5, Eric Yow5, Greg Evans6, Kelly L. Mieszkalski3, Norman T. Ilowite7, Emily von Scheven8, B. Anne Eberhard9, Lisa F. Imundo10, Yuki Kimura11, Earl D. Silverman12, Suzanne L. Bowyer13, Marilynn G. Punaro14, Nora G. Singer15, David D. Sherry16, Deborah K. McCurdy17, Marisa Klein-Gitelman18, Carol Wallace19, Richard M. Silver20, Linda Wagner-Weiner21, Gloria C. Higgins22 and Hermine Brunner23, 1Ohio State University, Columbus, OH, 2Duke University, Durham, NC, 3Duke University Medical Center, Durham, NC, 4Stanford University, Palo Alto, CA, 5Duke Clinical Research Institute, Durham, NC, 6Winston-Salem, NC, 7Children's Hospital Montefiore, Bronx, NY, 8UC San Francisco, San Francisco, CA, 9Cohen Children's Hospital Medical Center, New Hyde Park, NY, 10Childrens Hospital of New York, Columbia University Medical Center, New York, NY, 11Pediatrics, Hackensack, NJ, 12Hospital for Sick Children, Toronto, ON, 13James Whitcomb Riley Hospital, Indianapolis, IN, 14Texas Scottish Rite Hospital, Dallas, TX, 15Director, Division of Rheumatology, MetroHealth Medical Center, Case Western Reserve University, Cleveland, OH, 16Children's Hospital of Philadelphia, Philadelphia, PA, 17Mattel Children's Hospital, University of California, Los Angeles, Los Angeles, CA, 18Children's Memorial Hospital, Chicago, IL, 19Childrens Hosp & Regional Med, Seattle, WA, 20MUSC, Charleston, SC, 21University of Chicago Hospital, Chicago, IL, 22Nationwide Childrens Hosp, Columbus, OH, 23Cincinnati Children's Hospital Medical Center, Cincinnati, OH

Development of a Clinical Disease Activity Measure for Juvenile Localized Scleroderma
Suzanne C. Li1, Kathryn S. Torok2, Elena Pope3, Katie G. Stewart4, Gloria C. Higgins5, Egla C. Rabinovich6, Kathleen M. O'Neil7, Ivan Foeldvari8, Kathleen A. Haines1, Heidi Jacobe9, Marilynn G. Punaro4, Ronald M. Laxer10, Themba Nyirenda1 and Knut M. Wittkowski11, 1Hackensack University Medical Center, Hackensack, NJ, 2Univ of Pittsburgh Med Ctr, Pittsburgh, PA, 3Hospital for Sick Children, Toronto, ON, 4Texas Scottish Rite Hospital, Dallas, TX, 5Nationwide Childrens Hosp, Columbus, OH, 6Duke University Medical Center, Durham, NC, 7Okla Univ Health Science Ctr, Oklahoma City, OK, 8Hamburger Zentrum Kinder-und Jugendrheumatologie, Hamburg, Germany, 9UT Southwestern Medical Center at Dallas, Dallas, TX, 10The Hospital for Sick Children, Toronto, ON, 11Rockefeller University, NY

Cancer Risk In Pediatric Systemic Lupus: Updated Analyses
Sasha Bernatsky1, Rosalind Ramsey-Goldman2, Earl D. Silverman3, Ciaran M. Duffy4, Kiem Oen5, Alan M. Rosenberg6, Laura E. Schanberg7, Kathleen M. O'Neil8, Emily von Scheven9, Jeremy Labrecque1, Elizabeth M. Turnbull1 and Ann E. Clarke1, 1Research Institute of the McGill Univ. Health Ctre, Montreal, QC, 2Northwestern University, Chicago, IL, 3Hospital for Sick Children, Toronto, ON, 4Children's Hospital of Eastern Ontario, Ottawa, ON, 5University of Manitoba, Winnipeg, MB, 6Royal University Hospital, Saskatoon, SK, 7Duke University Medical Center, Durham, NC, 8Okla Univ Health Science Ctr, Oklahoma City, OK, 9UC San Francisco, San Francisco, CA

Hospital for Sick Children, University of Toronto
Development of Consensus Treatment Plans for New-Onset Systemic Juvenile Idiopathic Arthritis
Esi Morgan DeWitt, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, Timothy Beukelman, Univ of Alabama-Birmingham, Birmingham, AL, Peter A. Nigrovic, Brigham and Women's Hospital, Boston, MA, Karen Onel, University of Chicago, Chicago, IL, Sampath Prahalad, Emory Children's Center, Atlanta, GA, Rayfel Schneider, Hospital for Sick Children, University of Toronto, Toronto, ON, Matthew Stoll, UT Southwestern Medical Center, Dallas, TX, Norman T. Ilowite, Children's Hospital Montefiore, Bronx, NY, Carol A. Wallace, Childrens Hosp & Regional Med, Seattle, WA and Yukiko Kimura, Hackensack Univ Medical Ctr, Hackensack, NJ

The Impact of Advanced Clinician Practitioner in Arthritis Care Program-Trained Extended Role Practitioners on Health Care Delivery: A Two Year Prospective Study
Carol Kennedy1, Kelly Warmington1, Leslie J. Soever2, Laura A. Passalent3, Sydney C. Lineker4, Katie Lundon1, Rachel Shupak1 and Rayfel Schneider5, 1St. Michael's Hospital, Toronto, ON, 2Mount Sinai Hospital, Toronto, ON, 3University Health Network, Toronto, ON, 4The Arthritis Society, Toronto, ON, 5Hospital for Sick Children, University of Toronto, Toronto, ON

Patient Satisfaction with a New Healthcare Provider: Advanced Clinician Practitioner in Arthritis Care Program-Trained Clinicians
Kelly Warmington1, Carol Kennedy1, Sydney C. Lineker2, Leslie J. Soever3, Laura A. Passalent4, Katie Lundon1, Rachel Shupak1 and Rayfel Schneider5, 1St. Michael's Hospital, Toronto, ON, 2The Arthritis Society, Toronto, ON, 3Mount Sinai Hospital, Toronto, ON, 4University Health Network, Toronto, ON, 5Hospital for Sick Children, University of Toronto, Toronto, ON

Evaluation of Interprofessional Patient-Centred Collaborative Practice Behaviour and Perceptions Following An Intensive Continuing Education Development Initiative in Arthritis Care
Katie Lundon1, Carol Kennedy1, Kelly Warmington1, Linda Rozmovits2, Leslie J. Soever3, Laura A. Passalent4, Sydney C. Lineker5, Rachel Shupak6, Rayfel Schneider7 and Lynne Sinclair8, 1St. Michael's Hospital, Toronto, ON, 2Consultant, Toronto, ON, 3Mount Sinai Hospital, Toronto, ON, 4University Health Network, Toronto, ON, 5The Arthritis Society, Toronto, ON, 6St. Michaels Hospital, Toronto, ON, 7Hospital for Sick Children, University of Toronto, Toronto, ON, 8Toronto Rehabiltation Institute, Toronto, ON

An Overview of Clinical Performance by Advanced Clinician Practitioner in Arthritis Care Program-Trained Therapists: A Two-Year Prospective Study
Laura A. Passalent1, Carol Kennedy2, Leslie J. Soever3, Kelly Warmington2, Sydney C. Lineker4, Katie Lundon2, Rachel Shupak5 and Rayfel Schneider6, 1University Health Network, Toronto, ON, 2St. Michael's Hospital, Toronto, ON, 3Mount Sinai Hospital, Toronto, ON, 4The Arthritis Society, Toronto, ON, 5St. Michaels Hospital, Toronto, ON, 6Hospital for Sick Children, University of Toronto, Toronto, ON

Tocilizumab Is Efficacious in Patients with Systemic Juvenile Idiopathic Arthritis Across Baseline Demographic and Disease Characteristics and Prior/Baseline Treatments: 52-Week Data From a Phase 3 Clinical Trial
Fabrizio De Benedetti1, Hermine Brunner2, Roger Allen3, Diane Brown2, Jeffrey Chaitow3, Manuela Pardeo3, Graciela Espada3, Berit Flatø3, Gerd Horneff3, Clare Devlin4, Andrew Kenwright4, Rayfel Schneider5, Patricia Woo6, Alberto Martini3, Daniel Lovell2 and Nicola Ruperto3, 1IRCCS Ospedale Pediatrico Bambino Gesù, Rome, Italy, 2Pediatric Rheumatology Collaborative Study Group [PRCSG], Cincinnati, OH, 3Paediatric Rheumatology International Trials Organisation – IRCCS [PRINTO], Genova, Italy, 4Roche, Welwyn, United Kingdom, 5Hospital for Sick Children, University of Toronto, Toronto, ON, 6University College London Medical School, London, United Kingdom

Systemic Arthritis and Still's Disease
Rayfel Schneider, Hospital for Sick Children, University of Toronto, Toronto, ON
Hospital For Special Surgery
A Needs Assessment of Hospital for Special Surgery’s Charla De Lupus/Lupus Chat® Teen and Parent Support Group: Gaining a Community  Perspective on Nutritional Health to Inform  Implementation of a Nutrition Education Intervention
Jillian A. Rose1, Christie Carlstorm2, Roberta Horton1, Sandra Goldsmith1, Robyn Wiesel1 and Lisa F. Imundo3, 1Hospital for Special Surgery, New York, NY, 2Hospital For Special Surgery, New York, NY, 3Childrens Hospital of New York, Columbia University Medical Center, New York, NY
Hospital for Special Surgery
Type I Interferon and Clinical Phenotype in Idiopathic Inflammatory Myopathies
Louise Ekholm1, Anna Tjärnlund1, Clio P. Mavragani2, Peter J. Charles3, Leonid Padyukov1, Mary K. Crow4 and Ingrid E. Lundberg5, 1Rheumatology Unit, Department of Medicine, Karolinska University Hospital, Solna, Karolinska Institutet, Stockholm, Sweden, 2Department of Experimental Physiology, School of Medicine, University of Athens, Athens, Greece, 3Kennedy Institute of Rheumatology, Imperial College, London, United Kingdom, 4Hospital for Special Surgery, New York, NY, 5Karolinska Institutet, Stockholm, Sweden

Hospital for Special Surgery Rheumatology Academy of Medical Educators:  Planning Retreat Demonstrates a High Degree of Faculty Interest in Teaching, a Teaching Career and Formalized Education to Increase Competency
Jessica Berman1, Juliet Aizer1, Anne R. Bass1, William L. Cats-Baril2, Mary K. Crow3, Edward J. Parrish1, Laura Robbins3, Jane E. Salmon1 and Stephen A. Paget1, 1Hospital for Special Surgery, Weill Cornell Medical College, New York, NY, 2University of Vermont, Burlington, VT, 3Hospital for Special Surgery, New York, NY

Effects of Fasudil Treatment on Lupus Pathogenesis in NZB/W F1 Female Mice
Roslynn A. Stirzaker1, Partha S. Biswas1, Sanjay Gupta1, Weijia Yuan1, Li Song1, Uma Chandrasekaran1, Govind Bhagat2 and Alessandra B. Pernis1, 1Hospital for Special Surgery, New York, NY, 2Columbia University, New York, NY

Prevalence of Celiac Antibodies in Patients with Systemic Sclerosis
Lindsy J. Forbess1, Jessica K. Gordon1, Kamini Doobay2, Brian Bosworth3, Morgana L. Davids1 and Robert F. Spiera1, 1Hospital for Special Surgery, New York, NY, 2Hospital for Special Surgery, New York, 3New York Presbyterian Hospital, Weill Cornell Medical Center, New York, NY

Immunoglobulin Concentrations and Infection Risk Among Patients with ANCA-Associated Vasculitis Treated with Rituximab or Cyclophosphamide
Ulrich Specks1, Peter A. Merkel2, Philip Seo3, Robert F. Spiera4, Carol A. Langford5, Gary S. Hoffman5, Cees G.M. Kallenberg6, E. William St. Clair7, Swati Tole8, Paul Brunetta9, Shuyi Shen8, Nadia Tchao10, Barri J. Fessler11, Lisa Webber12, Linna Ding13, Lourdes P. Sejismundo14, Kathleen Mieras1, Deborah J. Phippard10, Adam Asare10, Noha Lim10, David Ikle15, Brett Jepson15, Alice Lail15 and Mark Mueller16, 1Mayo Clinic, Rochester, MN, 2Boston University School of Medicine, Boston, MA, 3Johns Hopkins Vasculitis Center, Baltimore, MD, 4Hospital for Special Surgery, New York, NY, 5Cleveland Clinic, Cleveland, OH, 6University Medical Center Groningen, Groningen, Netherlands, 7Duke University Medical Center, Durham, 8Genentech, Inc., South San Francisco, CA, 9Genentech, So San Francisco, CA, 10Immune Tolerance Network, Bethesda, MD, 11University of Alabama at Birmingham, Birmingham, AL, 12National Institute of Allergy and Infectious Diseases, 13NIAID, Bethesda, MD, 14Johns Hopkins University, Baltimore, MD, 15Rho, Chapel Hill, NC, 16Food & Drug Administration, Bethesda, MD

Serum Proteins Reflecting Inflammation, Injury, and Repair As Biomarkers of Disease Activity in ANCA-Associated Vasculitis
Paul A. Monach1, Roscoe L. Warner2, Gunnar Tomasson3, Ulrich Specks4, John H. Stone5, Linna Ding6, Fernando Fervenza4, Barri J. Fessler7, Gary S. Hoffman8, David Ikle9, Cees GM Kallenberg10, Jeffrey Krischer11, Carol A. Langford12, Mark Mueller13, Philip Seo14, E. William St Clair15, Robert F. Spiera16, Nadia Tchao17, Steven R. Ytterberg4, Kent J. Johnson2 and Peter A. Merkel3, 1Boston University, Boston, MA, 2University of Michigan, Ann Arbor, MI, 3Boston University School of Medicine, Boston, MA, 4Mayo Clinic, Rochester, MN, 5Massachusetts General Hospital, Boston, MA, 6NIAID, Bethesda, MD, 7University of Alabama at Birmingham, Birmingham, AL, 8Cleveland Clinic Found A50, Cleveland, OH, 9Rho, Chapel Hill, NC, 10University Medical Center Groningen, Groningen, Netherlands, 11University of South Florida, Tampa, FL, 12Cleveland Clinic, Cleveland, OH, 13Food & Drug Administration, Bethesda, MD, 14Johns Hopkins Vasculitis Center, Baltimore, MD, 15Duke University Medical Center, Durham, NC, 16Hospital for Special Surgery, New York, NY, 17Immune Tolerance Network, Bethesda, MD

Soluble CD14 in Synovial Fluid From Patients with Early-Stage Osteoarthritis Augments Synoviocyte Responses to TLR-2 and TLR-4 Ligands
Anjali Nair1, Veero Kanda1, Charles Bush-Joseph1, Nikhil Verma1, Susanna Chubinskaya1, Katalin Mikecz1, Tibor T. Glant1, Anne-Marie Malfait1, Mary K. Crow2, Greg Spear1, Alison Finnegan1 and Carla R. Scanzello1, 1Rush University Medical Center, Chicago, IL, 2Hospital for Special Surgery, New York, NY

Factors That Influence Appointment Compliance Rates In a Multi-Disciplinary Specialized Lupus Clinic
Pretima G. Persad1, Su Jin Kim2, Kyriakos A. Kirou1 and Doruk Erkan1, 1Mary Kirkland Center for Lupus Care- Hospital for Special Surgery, New York, NY, 2Hospital for Special Surgery, New York, NY

Immune-Complex Induced Inflammation Is Augmented in the Absence Nicotinic Acetylcholine Receptors in Mice
Milena Vukelic1, Gloria Koo1, Patricia M. Redecha1 and Jane E. Salmon2, 1Hospital for Special Surgery, New York, NY, 2Hospital for Special Surgery, Weill Cornell Medical College, New York, NY

Relationship Between Synovitis and Two-Year Post-Surgical Outcomes in Patients Undergoing Arthroscopic Partial meniscectomy 
Carla R. Scanzello1, Edward F. DiCarlo2, Veero Kanda1, Anthony Albert3, Steven R. Goldring2, John C. Richmond3 and Brian McKeon4, 1Rush University Medical Center, Chicago, IL, 2Hospital for Special Surgery, New York, NY, 3New England Baptist Hospital, MA, 4New England Baptist Hospital, Boston, MA

Deficiency of TACE in Myeloid Cells Prevents Arthritis in Mice
Priya Issuree, Weill Cornell Graduate School of Medical Sciences, New York, NY, Thorsten Maretzky, Hospital for Special Surgery, New York, NY, Kei Horiuchi, Keio University School of Medicine, Shinjuku-ku, Tokyo, Japan, Jane E. Salmon, Hospital for Special Surgery, Weill Cornell Medical College, New York, NY and Carl Blobel, Weill Cornell Medical College, Hospital for Special Surgery, New York, NY

A Phase 2 Study Evaluating the Acute Pain Relief of a Nano-Formulated Oral Naproxen
Garen Manvelian, Iroko Pharmaceuticals, Poway, CA, Stephen Daniels, Premier Research Group, Austin, TX, Allan Gibofsky, Hospital for Special Surgery, New York, NY and Vibeke Strand, Stanford University, Palo Alto, CA

Treatment Regimens of Patients Enrolled in the Lupus Clinical Trials Consortium (LCTC)
Alana B. Levine1, Doruk Erkan2, Jill P. Buyon3 and Michael D. Lockshin2, 1Hospital for Special Surgery, New York, NY, 2Barbara Volcker Center for Women and Rheumatic Diseases, Hospital for Special Surgery, New York, NY, 3NYU School of Medicine, New York, NY

Increased Relative Expression of the Interferon-Responsive Gene MX1 Is Present in Pregnant SLE Patients and May Distinguish Flare of SLE From Preeclampsia
Danieli Andrade1, Gloria Koo1, Patricia M. Redecha1, Kyriakos A. Kirou2, Mimi Kim3, Mary K. Crow1 and Jane E. Salmon4, 1Hospital for Special Surgery, New York, NY, 2Mary Kirkland Center for Lupus Care - Hospital for Special Surgery, New York, NY, 3Albert Einstein College of Medicine, Bronx, NY, 4Hospital for Special Surgery, Weill Cornell Medical College, New York, NY

Influenza Vaccine Intervention in a Rheumatology Clinic Population
Sherece Black1, Sarabjit Brar1, Lee Chang, Sylvia Chico1, Donald Makowski1, Virginia Haiduc1, Steven K. Magid3, Julie A. Pollino-Tanner1, Julita C. Reyes-Canu1, Ann M. Rakowicz1 and Monica C. Richey1, 1Hospital for Special Surgery, New York, NY, 2Hosp for Special Surgery, New York, NY

Incorporating the Patient Perspective: Developing a Patient-Focused Evaluation for An Early RA Support and Education Program
Meredith K. Wolrich, Adena Batterman, Roberta Horton, Linda Leff, Theodore R. Fields and Vanima Lalsa, Hospital for Special Surgery, New York, NY

A Needs Assessment of Hospital for Special Surgery’s Charla De Lupus/Lupus Chat® Teen and Parent Support Group: Gaining a Community  Perspective on Nutritional Health to Inform  Implementation of a Nutrition Education Intervention
Jillian A. Rose1, Christie Carlstorm2, Roberta Horton1, Sandra Goldsmith1, Robyn Wiesel1 and Lisa F. Imundo3, 1Hospital for Special Surgery, New York, NY, 2Hospital For Special Surgery, New York, NY, 3Childrens Hospital of New York, Columbia University Medical Center, New York, NY

One-Year Outcomes of Systemic Lupus Erythematosus (SLE) and/or Antiphospholipid Antibody (aPL) Positive Patients Enrolled in An Ongoing Cardiovascular Disease (CVD) Prevention Counseling Program (PCP)
Aeshita Dwivedi1, Virginia Haiduc1, Monica C. Richey1, Sotiria Everett1, Lisa Konstantellis1, Ann R. Garment2, Hassan Ghomrawi1 and Doruk Erkan1, 1Hospital for Special Surgery, New York, NY, 2Weill Cornell Medical Center, New York

Do Rheumatoid Arthritis Patients Expect Less From Total Knee Arthroplasty?
Hassan Ghomrawi1, Lisa A. Mandl2, Beverly Johnson2, Michael Alexiades2 and Susan M. Goodman2, 1Weil-Cornell Medical College, NYC, NY, 2Hospital for Special Surgery, New York, NY

Favorable Prognosis in a Large, Prospective Multicenter Study of Lupus Pregnancies
Jill P. Buyon1, Lamya Garabet2, Mimi Kim3, Emily R. Reeves2, Marta M. Guerra2, Michael D. Lockshin4, Carl A. Laskin5, Ware Branch6, Lisa R. Sammaritano2, Michelle Petri7, Joan T. Merrill8, Allen D. Sawitzke9 and Jane E. Salmon10, 1New York University School of Medicine, New York, NY, 2Hospital for Special Surgery, New York, NY, 3Albert Einstein College of Medicine, Bronx, NY, 4Barbara Volcker Center for Women and Rheumatic Diseases: Hospital for Special Surgery, New York, NY, 5University of Toronto and LifeQuest Centre for Reproductive Medicine, Toronto, ON, 6Univ of Utah, Salt Lake City, UT, 7Johns Hopkins University School of Medicine, Baltimore, MD, 8Oklahoma Medical Research Foundation, Oklahoma City, OK, 9University of Utah Medical Ctr, Salt Lake City, UT, 10Hospital for Special Surgery, Weill Cornell Medical College, New York, NY

Rapid Surges of Anti-dsDNA Titers Predict Severe Clinical Flares in Systemic Lupus Erythematosus
Nancy Pan1, Isabelle Amigues2, Rolando Duculan3, Faiza Aziz4, Stephen L. Lyman1, Mary K. Crow1 and Kyriakos A. Kirou1, 1Hospital for Special Surgery, New York, NY, 2Hospital Saint Joseph Saint Luc, Paris, France, 3Mary Kirkland Center for Lupus Research-Hospital for Special Surgery, New York, NY, 4Interfaith Medical Center, Brooklyn, NY

Clinical and Hemodynamic Features of Scleroderma Patients with Pulmonary Venous Hypertension Versus Pulmonary Arterial Hypertension
Jessica K. Gordon1, Kamini Doobay2, Evelyn Horn3, Marcy B. Bolster4, Lee S. Shapiro5, Dinesh Khanna6, Tracy M. Frech7, Kara Fields2, Chris T. Derk8, Laura K. Hummers9, Maureen D. Mayes10, Virginia D. Steen11 and PHAROS Investigators12, 1Hospital for Special Surgery, New York, NY, 2Hospital for Special Surgery, New York, 3Weill-Cornell Medical College, New York, NY, 4Medical Univ of South Carolina, Charleston, SC, 5Albany, NY, 6University of Michigan, Ann Arbor, MI, 7University of Utah School of Medicine, SLC, UT, 8Jefferson Medical College, Philadelphia, PA, 9Johns Hopkins University, Baltimore, MD, 10University of Texas Health Science Center at Houston, Houston, TX, 11Georgetown Univ Medical Center, Washington, DC, 12Washington

Mucocutaneous Flares As Opposed to Flares From Other Organs Have the Strongest Association with High Type I Interferon Levels in Patents with Systemic Lupus Erythematosus
Elzbieta E. Jacek1, Mikhail Olferiev2, Vinicius Domingues3, Rolando Duculan1, Nancy Pan4, Mary K. Crow4 and Kyriakos A. Kirou5, 1Mary Kirkland Center for Lupus Research-Hospital for Special Surgery, New York, NY, 2Mary Kirkland Center for Lupus Research, Hospital for Special Surgery, New York, NY, 3Estacio de Sá University, Rio de Janeiro, Brazil, 4Hospital for Special Surgery, New York, NY, 5Mary Kirkland Center for Lupus Care, Hospital for Special Surgery, New York, NY

The Accuracy of Patient Reported Current and Past Medications Used to Treat Rheumatoid Arthritis in An Academic Institutional Registry
Sergio Schwartzman1, Dana E. Orange2 and Stephen L. Lyman1, 1Hospital for Special Surgery, New York, NY, 2Hospital for Special Surgery, The Rockefeller University, New York, NY

Perioperative Use of Anti-TNF Medications in Patients with Rheumatoid Arthritis Undergoing Total Knee Replacement
Beverly Johnson, Susan M. Goodman, Michael Alexiades and Lisa A. Mandl, Hospital for Special Surgery, New York, NY

Hypophosphatemia Is Associated with Nephrogenic Systemic Fibrosis: A Case-Control Study
Elana J. Bernstein1, Tamara Isakova2, Mary E. Sullivan3, Lori B. Chibnik4, Hasan Bazari3, Myles Wolf2 and Jonathan Kay5, 1Hospital for Special Surgery, New York, NY, 2University of Miami, Miami, FL, 3Massachusetts General Hospital, Boston, MA, 4Brigham & Women's Hospital, Boston, MA, 5University of Massachusetts Medical School, Worcester, MA

Mental Health As a Predictor of Disease Flare in Granulomatosis with Polyangiitis (Wegener's Granulomatosis)
Morgana L. Davids1, Huong Do1, Gunnar Tomasson2, John C. Davis3, Gary S. Hoffman4, W. Joseph McCune5, Ulrich Specks6, E. William St Clair7, John H. Stone8, Peter A. Merkel9 and Robert F. Spiera1, 1Hospital for Special Surgery, New York, NY, 2Boston University School of Medicine, Boston, MA, 3Genentech Inc, South San Francisco, CA, 4Cleveland Clinic, Cleveland, OH, 5University of Michigan, Ann Arbor, MI, 6Mayo Clinic, Rochester, MN, 7Duke University Medical Center, Durham, NC, 8Massachusetts General Hospital, Boston, MA, 9Boston University, Boston, MA

Extended Follow-up of Treatment with Rituximab Versus Cyclophosphamide for Remission-Induction of ANCA-Associated Vasculitis: Which Subsets Are At Greatest Risk for Flare?
John H. Stone1, Peter A. Merkel2, Philip Seo3, Robert F. Spiera4, Carol A. Langford5, Gary S. Hoffman5, Cees GM Kallenberg6, E. William St. Clair7, Barri J. Fessler8, Nadia Tchao9, Lisa Webber10, Linna Ding11, Lourdes P. Sejismundo12, Kathleen Mieras13, David Ikle14, Deborah J. Phippard9, Brett Jepson14, Alice Lail14, Adam Asare9, Noha Lim9, Mark Mueller15, Paul Brunetta16, Nancy B. Allen17, Fernando Fervenza13, Duvuru Geetha18, Karina Keogh13, Eugene Y. Kissin19, Paul A. Monach19, Tobias Peikert13, Coen Stegeman6, Steven R. Ytterberg13, Ulrich Specks13 and for the RAVE-ITN Research Group20, 1Massachusetts General Hospital, Boston, MA, 2Boston University School of Medicine, Boston, MA, 3Johns Hopkins Vasculitis Center, Baltimore, MD, 4Hospital for Special Surgery, New York, NY, 5Cleveland Clinic, Cleveland, OH, 6University Medical Center Groningen, Groningen, Netherlands, 7Duke University Medical Center, Durham, 8University of Alabama at Birmingham, Birmingham, AL, 9Immune Tolerance Network, Bethesda, MD, 10National Institute of Allergy and Infectious Diseases, 11NIAID, Bethesda, MD, 12Johns Hopkins University, Baltimore, MD, 13Mayo Clinic, Rochester, MN, 14Rho, Chapel Hill, NC, 15Food & Drug Administration, Bethesda, MD, 16Genentech, So San Francisco, CA, 17Duke University Medical Center, Durham, NC, 18Johns Hopkins University, York, PA, 19Boston University, Boston, MA, 20Bethesda

Opposing Regulation of IFN Response Genes and STAT1 in Rheumatoid Arthritis Synovial Fluid Macrophages by TNFá and the Synovial Fluid Microenvironment
Rachael A. Gordon, Galina Grigoriev, George D. Kalliolias and Lionel B. Ivashkiv, Hospital for Special Surgery, New York, NY



Primary Thromboprophylaxis
Doruk Erkan, Hospital for Special Surgery, New York, NY

Management of Pregnancy
Lisa R. Sammaritano, Hospital for Special Surgery, New York, NY


The Challenges of Fertility and Pregnancy in Patients with Lupus
Michael D. Lockshin, Hospital for Special Surgery, New York, NY

Introduction: Pathophysiology of Bone Remodeling in Rheumatic Diseases
Steven R. Goldring, Hospital for Special Surgery, New York, NY

Feedback Mechanisms Regulating Osteoclastogenesis
Lionel B. Ivashkiv, Hospital for Special Surgery, New York, NY

Wrap-up
Steven R. Goldring, Hospital for Special Surgery, New York, NY and Georg Schett, Institute for Clinical Immunology, University of Erlangen-Nuremberg, Erlangen, Germany

Question and Answer
Doruk Erkan1, Munther A. Khamashta2 and Lisa R. Sammaritano1, 1Hospital for Special Surgery, New York, NY, 2Lupus Research Unit, The Rayne Institute, Kings College London School of Medicine, London, United Kingdom

Efficacy of Arthrocentesis Teaching Tools Including Cadavers and Synthetic Joint Models
Jessica Berman, Hospital for Special Surgery, New York, NY

Update on APS Action and APS Clinical Studies
Doruk Erkan, Hospital for Special Surgery, New York, NY


Introductions and Program Overview
Allan Gibofsky, Hospital for Special Surgery, New York, NY

Treat to Target: Review of Current Evidence
Allan Gibofsky, Hospital for Special Surgery, New York, NY
Hospital for Special Surgery, The Rockefeller University
The Accuracy of Patient Reported Current and Past Medications Used to Treat Rheumatoid Arthritis in An Academic Institutional Registry
Sergio Schwartzman1, Dana E. Orange2 and Stephen L. Lyman1, 1Hospital for Special Surgery, New York, NY, 2Hospital for Special Surgery, The Rockefeller University, New York, NY
Hospital for Special Surgery, Weill Cornell Medical College
Hospital for Special Surgery Rheumatology Academy of Medical Educators:  Planning Retreat Demonstrates a High Degree of Faculty Interest in Teaching, a Teaching Career and Formalized Education to Increase Competency
Jessica Berman1, Juliet Aizer1, Anne R. Bass1, William L. Cats-Baril2, Mary K. Crow3, Edward J. Parrish1, Laura Robbins3, Jane E. Salmon1 and Stephen A. Paget1, 1Hospital for Special Surgery, Weill Cornell Medical College, New York, NY, 2University of Vermont, Burlington, VT, 3Hospital for Special Surgery, New York, NY

Association of Androgen Receptor Gene Polymorphism with Damage in Systemic Lupus Erythematosus
Yun Deng1, Jennifer M. Grossman2, Qiong Fu1, William Martin1, Matthew Quirk1, Ornella J. Rullo3, Susan A. Boackle4, Chaim Putterman5, Jane E. Salmon6, Vasileios C. Kyttaris7, George C. Tsokos7, Erika Magdangal1, Lori Sahakian2, Weiling Chen1, Jennifer MP Woo3, Deborah K. McCurdy3, Chack-Yung Yu8, Bevra H. Hahn2, Maureen A. McMahon1 and Betty P. Tsao1, 1David Geffen School of Medicine University of California Los Angeles, Los Angeles, CA, 2UCLA David Geffen School of Medicine, Los Angeles, CA, 3Mattel Children's Hospital, University of California, Los Angeles, Los Angeles, CA, 4University of Colorado Denver School of Medicine, Aurora, CO, 5Albert Einstein College of Medicine, Bronx, NY, 6Hospital for Special Surgery, Weill Cornell Medical College, New York, NY, 7Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA, 87Center for Molecular and Human Genetics, The Research Institute at Nationwide Children's Hospital and The Ohio State University, Columbus, OH

Immune-Complex Induced Inflammation Is Augmented in the Absence Nicotinic Acetylcholine Receptors in Mice
Milena Vukelic1, Gloria Koo1, Patricia M. Redecha1 and Jane E. Salmon2, 1Hospital for Special Surgery, New York, NY, 2Hospital for Special Surgery, Weill Cornell Medical College, New York, NY

Deficiency of TACE in Myeloid Cells Prevents Arthritis in Mice
Priya Issuree, Weill Cornell Graduate School of Medical Sciences, New York, NY, Thorsten Maretzky, Hospital for Special Surgery, New York, NY, Kei Horiuchi, Keio University School of Medicine, Shinjuku-ku, Tokyo, Japan, Jane E. Salmon, Hospital for Special Surgery, Weill Cornell Medical College, New York, NY and Carl Blobel, Weill Cornell Medical College, Hospital for Special Surgery, New York, NY

Analysis of Endothelium from Systemic Lupus Erythematosus Patients Demonstrates a Marked Interferon Inducible Signature and an Associated Decrease in Transforming Growth Factor Beta Signaling Genes
Diana Goldenberg1, Mikhail Olferiev1, Duygu Onat2, Ante Harxhi2, Danieli Andrade1, Mary K. Crow1, Paolo Colombo2 and Jane E. Salmon1, 1Hospital for Special Surgery, Weill Cornell Medical College, New York, NY, 2Columbia University College of Physicians & Surgeons, New York, NY

Increased Relative Expression of the Interferon-Responsive Gene MX1 Is Present in Pregnant SLE Patients and May Distinguish Flare of SLE From Preeclampsia
Danieli Andrade1, Gloria Koo1, Patricia M. Redecha1, Kyriakos A. Kirou2, Mimi Kim3, Mary K. Crow1 and Jane E. Salmon4, 1Hospital for Special Surgery, New York, NY, 2Mary Kirkland Center for Lupus Care - Hospital for Special Surgery, New York, NY, 3Albert Einstein College of Medicine, Bronx, NY, 4Hospital for Special Surgery, Weill Cornell Medical College, New York, NY

Favorable Prognosis in a Large, Prospective Multicenter Study of Lupus Pregnancies
Jill P. Buyon1, Lamya Garabet2, Mimi Kim3, Emily R. Reeves2, Marta M. Guerra2, Michael D. Lockshin4, Carl A. Laskin5, Ware Branch6, Lisa R. Sammaritano2, Michelle Petri7, Joan T. Merrill8, Allen D. Sawitzke9 and Jane E. Salmon10, 1New York University School of Medicine, New York, NY, 2Hospital for Special Surgery, New York, NY, 3Albert Einstein College of Medicine, Bronx, NY, 4Barbara Volcker Center for Women and Rheumatic Diseases: Hospital for Special Surgery, New York, NY, 5University of Toronto and LifeQuest Centre for Reproductive Medicine, Toronto, ON, 6Univ of Utah, Salt Lake City, UT, 7Johns Hopkins University School of Medicine, Baltimore, MD, 8Oklahoma Medical Research Foundation, Oklahoma City, OK, 9University of Utah Medical Ctr, Salt Lake City, UT, 10Hospital for Special Surgery, Weill Cornell Medical College, New York, NY

Initial Results for the LFA Collective Data Analysis Initiative (LFA CDAI): How Do Subjects From Lupus Clinical Trials Randomized to Standard of Care Respond Over Time?
Kenneth C. Kalunian1, Mimi Kim2, Leslie M. Hanrahan3, Jean-Claude P. Becker4, Sabine Bongardt5, Paul Brunetta6, David Close7, Jorn Drappa7, Richard Furie8, Bevra H. Hahn9, Matthew Linnik10, Jane E. Salmon11, Neil Solomons12 and Joan T. Merrill13, 1UCSD School of Medicine, La Jolla, CA, 2Albert Einstein College of Medicine, Bronx, NY, 3Lupus Foundation of America, Washington, DC, 4Becker Clinical Reearch Consulting LLC, New York, NY, 5UCB Biosciences, 6Genentech, So San Francisco, CA, 7MedImmune Inc., 8North Shore-LIJ Health System, Lake Success, NY, 9UCLA David Geffen School of Medicine, Los Angeles, CA, 10Lilly Research Laboratories, 11Hospital for Special Surgery, Weill Cornell Medical College, New York, NY, 12Vifor Pharma, 13Oklahoma Medical Research Foundation, Oklahoma City, OK
Hospital for Special Surgery/Weill Cornell Med Col
Of Mice and Men: Is Chondrocyte Hypertrophy a Driving Force in OA Initiation or Progression?
Mary Goldring, Hospital for Special Surgery/Weill Cornell Med Col, New York, NY
Hospital Garcia de Orta
Performance of the Ankylosing Spondylitis Disease Activity Score (ASDAS) in Patients Under Biological Therapies in Daily Practice – Results From the Portuguese Register Reuma.Pt
Sofia Ramiro1, Pedro Machado2, Raquel Roque3, Helena Santos4, Joaquim Polido-Pereira5, Daniela Peixoto6, Cátia Duarte7, Fernando Pimentel-Santos8, Cândida Silva4, J. E. Fonseca5, Filipa Teixeira6, Andrea Marques7, Filipe Araújo8, Jaime C. Branco8, José Pereira Da-Silva7, José Costa6, Jose A. Pereira Da Silva9, Luis Cunha Miranda4, J. Canas da Silva3, Helena Canhão5, A.M. Van Tubergen10, Desirée van der Heijde11, Robert Landewé12 and MJ Santos3, 1Hospital Garcia de Orta, Almada, Portugal and Academic Medical Center, University of Amsterdam, Amsterdam, Netherlands, 2Hospitais da Universidade de Coimbra, Coimbra, Portugal and Leiden University Medical Center, Leiden, Netherlands, 3Hospital Garcia de Orta, Almada, Portugal, 4Instituto Português de Reumatologia, Lisboa, Portugal, 5Instituto de Medicina Molecular, Faculdade de Medicina da Universidade de Lisboa and Rheumatology Department, Centro Hospitalar de Lisboa Norte, EPE, Hospital de Santa Maria, Lisboa, Portugal, 6Centro Hospitalar do Alto Minho, Hospital de Ponte de Lima, Ponte de Lima, Portugal, 7Hospitais da Universidade de Coimbra, Coimbra, Portugal, 8Centro Hospitalar de Lisboa Ocidental, Hospital Egas Moniz, Lisboa, Portugal, 9Centro Hospitalar de Lisboa Norte, Hospital de Santa Maria, Lisboa, Portugal, 10Maastricht University Medical Center, Maastricht, Netherlands, 11Leiden University Medical Center, Leiden, Netherlands, 12Academic Medical Center, University of Amsterdam, Amsterdam, Netherlands

Clinical and Radiological Manifestations of Ankylosing Spondylitis: Gender Differences
Fernando Pimentel-Santos1, Ana F. Mourão2, Célia Ribeiro1, José Costa3, Helena Santos4, Anabela Barcelos5, Patricia Pinto6, Fátima Godinho7, Margarida Cruz8, Elsa Vieira-Sousa9, Jorge Félix10, J. E. Fonseca11, Henrique Guedes-Pinto12 and Jaime C. Branco1, 1Centro Hospitalar de Lisboa Ocidental, Hospital Egas Moniz, Lisboa, Portugal, 2Rheumatology Research Unit, Instituto de Medicina Molecular, Faculdade de Medicina da Universidade de Lisboa and Rheumatology Department, Centro Hospitalar de Lisboa Ocidental, EPE, Hospital Egas Moniz, Lisbon, Portugal, 3Centro Hospitalar do Alto Minho, Hospital de Ponte de Lima, Ponte de Lima, Portugal, 4Instituto Português de Reumatologia, Lisboa, Portugal, 5Hospital Infante D. Pedro, 6Centro Hospitalar de Vila Nova de Gaia/Espinho EPE, 7Hospital Garcia de Orta, 8Centro Hospitalar Oeste Norte, Centro Hospitalar das Caldas da Rainha, 9Instituto de Medicina Molecular, Faculdade de Medicina da Universidade de Lisboa, Lisbon, Portugal, 10EXIGO Consultores, 11Instituto de Medicina Molecular, Faculdade de Medicina da Universidade de Lisboa and Rheumatology Department, Centro Hospitalar de Lisboa Norte, EPE, Hospital de Santa Maria, Lisboa, Portugal, 12Universidade de Trás-os-Montes e Alto Douro

Bridging ELISA As a Screening Assay to Monitor Immunogenicity in Routine Clinical Practice
Sandra Garcês, Instituto Gulbenkian Ciência; Hospital Garcia de Orta, Oeiras, Portugal, Jocelyne Demengeot, Instituto Gulbenkian Ciência, Oeiras, Portugal, J. Canas da Silva, Hospital Garcia de Orta, Almada, Portugal and L. Aarden, Sanquin Research and Landsteiner Laboratory, Amsterdam, Netherlands
Hospital Garcia de Orta, Almada, Portugal and Academic Medical Center, University of Amsterdam
Performance of the Ankylosing Spondylitis Disease Activity Score (ASDAS) in Patients Under Biological Therapies in Daily Practice – Results From the Portuguese Register Reuma.Pt
Sofia Ramiro1, Pedro Machado2, Raquel Roque3, Helena Santos4, Joaquim Polido-Pereira5, Daniela Peixoto6, Cátia Duarte7, Fernando Pimentel-Santos8, Cândida Silva4, J. E. Fonseca5, Filipa Teixeira6, Andrea Marques7, Filipe Araújo8, Jaime C. Branco8, José Pereira Da-Silva7, José Costa6, Jose A. Pereira Da Silva9, Luis Cunha Miranda4, J. Canas da Silva3, Helena Canhão5, A.M. Van Tubergen10, Desirée van der Heijde11, Robert Landewé12 and MJ Santos3, 1Hospital Garcia de Orta, Almada, Portugal and Academic Medical Center, University of Amsterdam, Amsterdam, Netherlands, 2Hospitais da Universidade de Coimbra, Coimbra, Portugal and Leiden University Medical Center, Leiden, Netherlands, 3Hospital Garcia de Orta, Almada, Portugal, 4Instituto Português de Reumatologia, Lisboa, Portugal, 5Instituto de Medicina Molecular, Faculdade de Medicina da Universidade de Lisboa and Rheumatology Department, Centro Hospitalar de Lisboa Norte, EPE, Hospital de Santa Maria, Lisboa, Portugal, 6Centro Hospitalar do Alto Minho, Hospital de Ponte de Lima, Ponte de Lima, Portugal, 7Hospitais da Universidade de Coimbra, Coimbra, Portugal, 8Centro Hospitalar de Lisboa Ocidental, Hospital Egas Moniz, Lisboa, Portugal, 9Centro Hospitalar de Lisboa Norte, Hospital de Santa Maria, Lisboa, Portugal, 10Maastricht University Medical Center, Maastricht, Netherlands, 11Leiden University Medical Center, Leiden, Netherlands, 12Academic Medical Center, University of Amsterdam, Amsterdam, Netherlands
Hospital General "Dr. Miguel Silva"
Early Rheumatoid Arthritis in Latin America. Low Socioeconomic Status Relates to High Disease Activity At Baseline
Loreto Massardo, Catholic University of Chile, Santiago 114-D, Chile, Bernardo A. Pons-Estel, Hospital Provincial, Rosario, Argentina, Mario H. Cardiel, Hospital General "Dr. Miguel Silva", Morelia, Mexico, Claudio Galarza-Maldonado, Hospital Monte Sinai , BIOMAB IPS, Cuenca, Ecuador, Mónica P. Sacnun, Hosp. Provincial, Rosario, Argentina, Enrique R. Soriano, Hospital Italiano de Buenos Aires, Buenos Aires, Argentina, Ieda Laurindo, Universidade de São Paulo, Sao Paulo, Brazil, Eduardo M. Acevedo-Vásquez, Hospital Nacional “Guillermo Almenara Irigoyen”, Lima, Peru, Carlo V. Caballero-Uribe, Continential Med Ctr, Barranquilla, Colombia, Oslando Padilla, Pontificia Universidad Catolica de Chile, Santiago, Chile, Marlene Guibert-Toledano, Centro de Investigaciones Médico Quirúrgicas, Habana, Ciudad Habana, Cuba, Rubén A. Montufar Guardado, Instituto Salvadoreño del Seguro Social, San Salvador, El Salvador, Sergio H. Jacobelli, Universidad Catolica de Chile, Santiago, Chile and Daniel E. Furst, UCLA Medical School, Los Angeles, CA
Hospital General CMN La Raza, IMSS
SELF-Administered Systemic Sclerosis Questionnaire. Validation of A SPANISH Version (SYSQ) In Mexicans
Maria Pilar Cruz-Dominguez1, Moises Casarrubias-Ramirez1, Victor Gasca Martínez1, Olga Lidia Vera Lastra1, Luis J. Jara Quezada2 and Daniel Hector Montes-Cortes3, 1Hospital de Especialidades CMN La Raza, IMSS, Mexico, DF, Mexico, 2Hospital de Especialidades CMN La Raza, IMSS, Mexico City, Mexico, 3Hospital General CMN La Raza, IMSS, Mexico DF, Mexico
Hospital General de Castellon
Development and Validation of a New Disease Activity Index As a Numerical Sum of 4 Variables, Including Erythrocyte Sedimentation Rate and/or C-Reactive Protein, to Assess Rheumatoid Arthritis
Isabel Castrejón1, Loreto Carmona2, Ana M. Ortiz3, Miguel A. Belmonte Serrano4, Juan A. martínez-López5 and Isidoro González-Alvaro3, 1NYU Hospital for Joint Diseases, New York, NY, 2Universidad Camilo José Cela, Villanueva de la Cañada, Spain, 3Hospital Universitario de La Princesa. IIS Princesa, Madrid, Spain, 4Hospital General de Castellon, Castellon, Spain, 5Fundación Jimenez Díaz, Madrid, Spain
Hospital General de Cuernavaca
Association Between Leptin, Adiponectin and TNF-α and Response to Treatment in Patients with Rheumatoid Arthritis
Daniel X. Xibille Friedmann1, Sara Eugenia Hernandez Gongora2, Carolina Bustos Bahena3, Liliana Dominguez Hernandez3, Ivan Martinez Rivera3, Marisol Sandoval Rios3, Jorge Eduardo Ortiz Panozo4 and Jose Luis Montiel Hernandez5, 1Hospital General de Cuernavaca, Cuernavaca Morelos, Mexico, 2Postgraduate Research Coordination, School of Medicine, Universidad Latinoamericana, Cuernavaca, México, 3Cytokines and Autoimmunity Laboratory, Faculty of Pharmacy, Universidad Autónoma del Estado de Morelos, Cuernavaca, México, Cuernavaca, Mexico, 4Center for Population Health Research. Instituto Nacional de Salud Pública, Cuernavaca, México, 5Cytokines and Autoimmunity Laboratory, Faculty of Pharmacy, Universidad Autónoma del Estado de Morelos, Cuernavaca, México
Hospital General de Granollers
Are Training Sessions Useful for Ultrasound Scan Evaluation of Synovitis In Rheumatoid Arthritis?
Andrés Ponce, Hospital General de Granollers, Granollers, Spain, Juan J. Alegre, Hospital Universitario Dr Peset, Valencia, Spain, Manuel Castaño, Hospital Universitario Virgen de la Arrixaca, Murcia, Spain, Ricardo Gutierrez-Polo, C.H. de Navarra, Pamplona, Spain, Francisco G. Jiménez-Núñez, Hospital Regional Universitario Carlos Haya., Malaga, Spain, María P. Macarrón, Hospital Clínico San Carlos, Madrid, Spain and Jesús Garrido, Facultad de Psicología.Universidad Autónoma de Madrid, Madrid, Spain
Hospital General de Hospitalet
Changes in Psychological Status in Patients with Chronic Spondyloarthropathy Treated with Infliximab
Rosa M. Morlà1, Hector Corominas2, M. V. Hernandez3, Mireia Moreno4, Miquel Sala5, Vera Ortiz-Santamaria6, Patricia Reyner6, Vicente Torrente-Segarra Jr.7, Agusti Sellas Fernandez8, Georgina Salvador9, Elena Sirvent10, Cristina Masuet11 and Xavier Juanola-Roura12, 1Hospital Sta Tecla, Tarragona, Spain, 2Hospital Moises Broggi, Barcelona, 3Hospital Clinic of Barcelona, Barcelona, Spain, 4Servei de Reumatologia, Sabadell, Spain, 5Rheumatology Unit, Figueres, Spain, 6Unitat de Reumatologia, Spain, 7Hospital General de Hospitalet, Barcelona, Spain, 8Senior Consultant, Barcelon, Spain, 9Hospital Mutua de Terrassa. Barcelona, Barcelona, Spain, 10Hospital de Sant Boi, 11Hospital de Bellvitge, Hospitalet de LLobregat, Spain, 12Hospital Universitario de Bellvitge, Barcelona, Spain
Hospital General de Manresa
Interferon-γ Release Assays In Rheumatic Patients: Baseline Study and In the Course of Anti-Tumor Necrosis Factor-α Agents
Melania Martínez-Morillo1, Sonia Mínguez2, Lourdes Mateo-Soria1, Irene Latorre1, José Domínguez1, Dolors Grados1, Beatriz Tejera1, Susana Holgado1, Alejandro Olivé1 and Xavier Tena1, 1Hospital Universitario Germans Trias i Pujol, Badalona, Spain, 2Hospital General de Manresa, Manresa, Spain
Hospital Gregorio Maranon
Undetectable Rheumatoid Factor Following Treatment with Rituximab- What Is Clinical Significance?
Pravin Patil1, Julia Flint1, Elena Becerra-Fernandez1, Inmaculada de la Torre2, Geraldine Cambridge1, Maria J. Leandro1 and Jonathan CW Edwards1, 1University College of London, London, United Kingdom, 2Hospital Gregorio Maranon, Madrid, Spain
Hospital Gustavo Fricke
Clinical and Genetic Features of Autoinflammatory Syndromes in Hispanic Patients: The Chilean Experience
Cristian Vergara1, Arturo Borzutzky1, Miguel A. Gutierrez1, Sergio Iacobelli1, Eduardo Talesnik1, Maria Eugenia Martinez1, Lilith Stange1, Javier Basualdo2, Viviana Maluje3, Renato Jimenez4, Elena Jarpa5, Roberto Wiener6, Javier Tinoco6, Juan I. Arostegui7, Jordi Yague7 and Manuel Alvarez-Lobos1, 1Pontificia Universidad Catolica de Chile, Santiago, Chile, 2Universidad de Chile, Santiago, Chile, 3Hospital FACH, Santiago, Chile, 4Hospital Gustavo Fricke, Valparaiso, Chile, 5Hospital Naval Almirante Nef, Vina Del Mar, Chile, 6Hospital Militar, Santiago, Chile, 7Hospital Clínic / IDIBAPS, Barcelona, Spain
Hospital Infante D. Pedro
Clinical and Radiological Manifestations of Ankylosing Spondylitis: Gender Differences
Fernando Pimentel-Santos1, Ana F. Mourão2, Célia Ribeiro1, José Costa3, Helena Santos4, Anabela Barcelos5, Patricia Pinto6, Fátima Godinho7, Margarida Cruz8, Elsa Vieira-Sousa9, Jorge Félix10, J. E. Fonseca11, Henrique Guedes-Pinto12 and Jaime C. Branco1, 1Centro Hospitalar de Lisboa Ocidental, Hospital Egas Moniz, Lisboa, Portugal, 2Rheumatology Research Unit, Instituto de Medicina Molecular, Faculdade de Medicina da Universidade de Lisboa and Rheumatology Department, Centro Hospitalar de Lisboa Ocidental, EPE, Hospital Egas Moniz, Lisbon, Portugal, 3Centro Hospitalar do Alto Minho, Hospital de Ponte de Lima, Ponte de Lima, Portugal, 4Instituto Português de Reumatologia, Lisboa, Portugal, 5Hospital Infante D. Pedro, 6Centro Hospitalar de Vila Nova de Gaia/Espinho EPE, 7Hospital Garcia de Orta, 8Centro Hospitalar Oeste Norte, Centro Hospitalar das Caldas da Rainha, 9Instituto de Medicina Molecular, Faculdade de Medicina da Universidade de Lisboa, Lisbon, Portugal, 10EXIGO Consultores, 11Instituto de Medicina Molecular, Faculdade de Medicina da Universidade de Lisboa and Rheumatology Department, Centro Hospitalar de Lisboa Norte, EPE, Hospital de Santa Maria, Lisboa, Portugal, 12Universidade de Trás-os-Montes e Alto Douro
Hospital Infantil de México Federico Gómez
Health-Related Quality of Life Among Patients with Osteoporotic Fractures In Mexico
Patricia Clark1, Fernando Carlos2, Gabriela Chico1, Oskar Ström3, Ingrid Lekander3 and Fredrik Borgström3, 1Hospital Infantil de México Federico Gómez, Mexico City, Mexico, 2RAC Salud Consultores, S.A. de C.V., Mexico, Mexico, 3Innovus, Sweden
Hospital Interzonal General de Agudos “General San Martin, La Plata
The Protective Effect of Antimalarials On Thrombovascular Events In Latin American Systemic Lupus Erythematosus Patients
Guillermo J. Pons-Estel, Servicio de Enfermedades Autoinmunes, Hospital Clìnic Barcelona, Barcelona, Spain, Graciela S. Alarcón, University of Alabama at Birmingham, Birmingham, AL, Daniel Wojdyla, Universidad Nacional de Rosario, Argentina, Rosario, Argentina, Ana I. Marcos, Hospital Interzonal General de Agudos “General San Martin, La Plata, La Plata, Argentina, Alejandro J. Alvarellos, Hospital Privado, Cordoba, Argentina, Antonio A. Iglesias-Gamarra, Universidad Nacional, Bogota, Colombia, Maria H. Esteva-Spinetti, Centro Clinico San Cristobal, San Cristobal, Venezuela, Lilian Costallat, Faculdade de Ciencias Medicas, Universidade Estadual de Campinas, Campinas, Brazil, Nilzio A. Silva, Faculdade de Medicina, Universidade Federal de Goias, Goiania, Brazil, Gloria Vázquez, Universidad de Antioquia, Hospital Universitario “San Vicente de Paul”, Medellín, Colombia, Maria Loreto Massardo, Catholic University of Chile, Santiago, Chile, Marlene Guibert-Toledano, Centro de Investigaciones Médico Quirúrgicas, Habana, La Habana, Cuba, Guillermo F. Huerta-Yáñez, Hospital de Especialidades Miguel Hidalgo, Aguascalientes, Mexico, Mariano Cucho-Venegas, Almenara Hospital IPSs, Lima, Peru and Bernardo Pons-Estel, Hospital Provincial de Rosario, Rosario, Argentina
Hospital Italiano
Work Disability Is Related to the Presence of Arthritis, Not to a Specific Diagnosis
Hernan Maldonado Ficco1, Rodolfo Perez Alamino1, Fernando Dal Pra1, Veronica Lencina1, Luciana Casalla2, Mariana Benegas2, Oscar Rillo3, Alberto Berman4, Ana Lucía Barbaglia4, Veronica Bellomio5, Francisco Caeiro6, Josefina Marcos7, Juan Carlos Marcos7, Antonio Catalan Pellet8, Rodrigo Garcia Salinas8, Sergio Paira9, Federico Ceccato9, Enrique Soriano10, Zaida Bendran10, Gabriela Salvatierra11 and Gustavo Citera1, 1Instituto de Rehabilitación Psicofísica, Buenos Aires, Argentina, 2Hospital Tornu, Buenos Aires, Argentina, 3Hospital Sirio Libanes, Buenos Aires, Argentina, 4Hospital Padilla, Tucuman, Argentina, 5Consultorio, Tucuman, Argentina, 6Hospital Privado de Cordoba, Cordoba, Argentina, 7Hospital San Martin, La Plata, Argentina, 8Hospital Rivadiavia, Buenos Aires, Argentina, 9Hospital Jose Maria Cullen, Santa Fe, Argentina, 10Hospital Italiano, Buenos Aires, Argentina, 11Centro de enfermedades Reumaticas, Santiago Del Estero, Argentina
Hospital Italiano de Buenos Aires
Why Do Lupus Patients Go to the Emergency Department in the United States?
Marina Scolnik1, Ajitha Mannalithara2, Enrique R. Soriano1 and Gurkirpal Singh2, 1Hospital Italiano de Buenos Aires, Buenos Aires, Argentina, 2Stanford University School of Medicine, Palo Alto, CA

Early Rheumatoid Arthritis in Latin America. Low Socioeconomic Status Relates to High Disease Activity At Baseline
Loreto Massardo, Catholic University of Chile, Santiago 114-D, Chile, Bernardo A. Pons-Estel, Hospital Provincial, Rosario, Argentina, Mario H. Cardiel, Hospital General "Dr. Miguel Silva", Morelia, Mexico, Claudio Galarza-Maldonado, Hospital Monte Sinai , BIOMAB IPS, Cuenca, Ecuador, Mónica P. Sacnun, Hosp. Provincial, Rosario, Argentina, Enrique R. Soriano, Hospital Italiano de Buenos Aires, Buenos Aires, Argentina, Ieda Laurindo, Universidade de São Paulo, Sao Paulo, Brazil, Eduardo M. Acevedo-Vásquez, Hospital Nacional “Guillermo Almenara Irigoyen”, Lima, Peru, Carlo V. Caballero-Uribe, Continential Med Ctr, Barranquilla, Colombia, Oslando Padilla, Pontificia Universidad Catolica de Chile, Santiago, Chile, Marlene Guibert-Toledano, Centro de Investigaciones Médico Quirúrgicas, Habana, Ciudad Habana, Cuba, Rubén A. Montufar Guardado, Instituto Salvadoreño del Seguro Social, San Salvador, El Salvador, Sergio H. Jacobelli, Universidad Catolica de Chile, Santiago, Chile and Daniel E. Furst, UCLA Medical School, Los Angeles, CA
Hospital Jose Maria Cullen
Prevalence and Correlates of Metabolic Syndrome in Patients with Rheumatoid Arthritis
Maria Haye Salinas1, Ana M. Bertoli2, Francisco Caeiro3, Luis Lema4, Veronica Bellomio5, Santiago Aguero6, Federico Ceccato7, Carla Saucedo8, Javier Rosa8, R. Quintana9, Marcela Schmid10, Walter Spindler11, Natalia Tamborenea12, Sergio Paira7, Bernardo Pons Estel13, Alberto J. Spindler14, Enrique R. Soriano8, Alejandro J. Alvarellos15 and Veronica Saurit16, 1Hospital Privado, Córdoba, Argentina, 2Instituto Reumatológico Strusberg, Cordoba, Cordoba, Argentina, 3Hospital Privado de Cordoba, Cordoba, Argentina, 4Instituto Modelo de Cardiologia, Cordoba, Argentina, 5Consultorio, Tucuman, Argentina, 6Centro de Rehabilitación II, Catamarca, Argentina, 7Hospital Jose Maria Cullen, Santa Fe, Argentina, 8Rheumatology Unit, Internal Medical Services, Hospital Italiano de Buenos Aires, Buenos Aires, Argentina, 9Hospital Provincial, Rosario, Argentina, 10Hospital Cullen, Santa Fe, Argentina, 11Centro Medico Privado, Tucuman, Argentina, 12Consultorio, Buenos Aires, Argentina, 13Sanatorio Parque, Rosario, Argentina, 14Universidad Nacional Tucumán, Yerba Buena Tucuman, Argentina, 15Hospital Privado, Cordoba, Argentina, 16Hospital Privado Córdoba, Córdoba, Argentina

Work Disability Is Related to the Presence of Arthritis, Not to a Specific Diagnosis
Hernan Maldonado Ficco1, Rodolfo Perez Alamino1, Fernando Dal Pra1, Veronica Lencina1, Luciana Casalla2, Mariana Benegas2, Oscar Rillo3, Alberto Berman4, Ana Lucía Barbaglia4, Veronica Bellomio5, Francisco Caeiro6, Josefina Marcos7, Juan Carlos Marcos7, Antonio Catalan Pellet8, Rodrigo Garcia Salinas8, Sergio Paira9, Federico Ceccato9, Enrique Soriano10, Zaida Bendran10, Gabriela Salvatierra11 and Gustavo Citera1, 1Instituto de Rehabilitación Psicofísica, Buenos Aires, Argentina, 2Hospital Tornu, Buenos Aires, Argentina, 3Hospital Sirio Libanes, Buenos Aires, Argentina, 4Hospital Padilla, Tucuman, Argentina, 5Consultorio, Tucuman, Argentina, 6Hospital Privado de Cordoba, Cordoba, Argentina, 7Hospital San Martin, La Plata, Argentina, 8Hospital Rivadiavia, Buenos Aires, Argentina, 9Hospital Jose Maria Cullen, Santa Fe, Argentina, 10Hospital Italiano, Buenos Aires, Argentina, 11Centro de enfermedades Reumaticas, Santiago Del Estero, Argentina
Hospital La Paz. IdiPaz
The STAT4 rs7574865 Polymorphism Is Associated with Differences in Disease Activity and Disability in Patients Wirh Early Arthritis
Ana M. Ortiz1, Amalia Lamana1, Alejandro Balsa2, Blanca Rueda3, Laura Nuño2, Maria Eugenia Miranda-Carus2, María F. González-Escribano4, Miguel A. López-Nebot5, Dora Pascual-Salcedo2, Javier Martin6 and Isidoro González-Alvaro1, 1Hospital Universitario de La Princesa. IIS Princesa, Madrid, Spain, 2Hospital La Paz. IdiPaz, Madrid, Spain, 3Facultad de Ciencias de la Salud. Universidad de Granada, Granada, Spain, 4Hospital Universitario Virgen del Rocío, Sevilla, Spain, 5Hospital Universitario Virgen de las Nieves, Granada, Spain, 6Instituto de Parasitologia y Biomedicina Lopez-Neyra (CSIC), Granada, Spain
Hospital Lapeyronie
A Single Injection of Adipose-Derived Stem cells protects Against Cartilage Damage and Lowers Synovial Activation in Experimental Osteoarthritis
Menno C. ter Huurne1, Peter L.E.M. van Lent1, Arjen B. Blom1, Roxane Blattes2, Yannick Jeanson2, Louis Casteilla2, Christian Jorgensen3 and Wim B. van den Berg1, 1Radboud University Nijmegen Medical Centre, Nijmegen, Netherlands, 2INSERM U1031, Toulouse, France, 3Hospital Lapeyronie, Montpellier, France

Active Immunization Against IFNα with IFN-Kinoid in SLE Patients Is Safe, Immunogenic and Induces Down-Regulation of IFN-Mediated Genes
Frédéric A. Houssiau1, Raskov Rashkov2, Eric Hachulla3, Estibaliz Lazaro4, Christian Jorgensen5, François Spertini6, Xavier Mariette7, Géraldine Grouard-Vogel8, Bernard Fanget8, Olivier Dhellin8, Bernard Lauwerys1 and Pierre Vandepapelière8, 1Université catholique de Louvain, Brussels, Belgium, 2MHAT Sveti Ivan Rilski, Sofia, Bulgaria, 3Internal Medicine, Lille CEDEX, France, 4Hôpital Haut-Lévêque, Pessac, France, 5Hospital Lapeyronie, Montpellier, France, 6CHU Vaudois, Lausanne, Switzerland, 7Université Paris-Sud, Le Kremlin Bicetre, France, 8NEOVACS SA, Paris, France
Hospital León
High Dose Intravenous Methylprednisolone Induces Rapid Improvement In Severe Uveitis: A Multicenter Study
Carmen Bejerano1, Ricardo Blanco1, Emma Beltrán2, Alejandro Fonollosa3, Olga Maiz4, Ana Blanco-Esteban4, Miguel Cordero5, Inés Pérez-Martín6, Joaquín Cañal6, Juan Ventosa6 and Miguel Angel González-Gay6, 1Hospital Universitario Marqués de Valdecilla-IFIMAV, Santander, Spain, 2Hospital Peset, Valencia, Spain, 3Hospital de Cruces, Barakaldo-Bilbao, Spain, 4Hospital Donostia, San Sebastian, Spain, 5Hospital León, León, Spain, 6Hospital Universitario Marqués de Valdecilla. IFIMAV, Santander, Spain
Hospital Marina Baixa
Evaluation of Anti-Tumor Necrosis Factor Levels and Anti-Tumor Necrosis Factor Antibodies in Rheumatic Diseases Treated with Infliximab and Adalimumab; Preliminary Results From a Local Registry
José Rosas-Gómez de Salazar1, Francisca Llinares-Tello1, José M. Senabre-Gallego1, Gregorio Santos-Soler1, Carlos Santos-Ramírez2, Esteban Salas-Heredia1, Xavier Barber-Vallés3, Mabel Sánchez-Barrioluengo4, Juan Molina-García1, Nuria Llahí Vidal1 and Catalina Cano Pérez1, 1Hospital Marina Baixa, Villajoyosa, Spain, 2Hospital Marina Salud, Denia, Spain, 3University Miguel Hernández, Elche, Spain, 4Universitat Politècnica de València, Valencia, Spain
Hospital Marina Salud
Evaluation of Anti-Tumor Necrosis Factor Levels and Anti-Tumor Necrosis Factor Antibodies in Rheumatic Diseases Treated with Infliximab and Adalimumab; Preliminary Results From a Local Registry
José Rosas-Gómez de Salazar1, Francisca Llinares-Tello1, José M. Senabre-Gallego1, Gregorio Santos-Soler1, Carlos Santos-Ramírez2, Esteban Salas-Heredia1, Xavier Barber-Vallés3, Mabel Sánchez-Barrioluengo4, Juan Molina-García1, Nuria Llahí Vidal1 and Catalina Cano Pérez1, 1Hospital Marina Baixa, Villajoyosa, Spain, 2Hospital Marina Salud, Denia, Spain, 3University Miguel Hernández, Elche, Spain, 4Universitat Politècnica de València, Valencia, Spain
Hospital Marques De Valdecilla
Association of Ferritin Antibodies with GCA/PMR: New Biomarker for Diagnosis
Niklas T. Baerlecken, MD, Hannover, Germany, Anna Linnemann, Student, Hannover, Germany, Wolfgang L. Gross, Medical University at Lubeck, Lubeck, Germany, Frank Moosig, Stormarnzing 156, Bad Bramstedt, Germany, T.R. Vazquez-Rodriguez, MD, Spain, Miguel Gonzalez-Gay, Hospital Marques De Valdecilla, Santander, Spain, Javier Martin, Instituto de Parasitologia y Biomedicina Lopez-Neyra (CSIC), Granada, Spain, Ina Kötter, MD, Tübingen, Germany, Joerg C. Henes, University Hospital Tuebingen, Tuebingen, Germany, Inga Melchers, PhD, Freiburg, Germany, Peter Vaith, Medizinische Uni Klinik, Freiburg, Germany, Reinhold E. Schmidt, Hannover Medical School, Hannover, Germany and Torsten Witte, MD, Hanover, Germany

Immunochip Genotyping of 1,884 Systemic Sclerosis Cases and 4,325 Controls Reveals Novel Associations
Maureen D. Mayes1, Olga Y. Gorlova2, Lara Bossini-Castillo3, Jose Ezequiel Martin4, Jun Ying2, Peter K. Gregersen5, Annette T. Lee6, Shervin Assassi1, Sandeep K. Agarwal1, Filemon K. Tan1, John D. Reveille1, Xiaodong Zhou1, Frank C. Arnett1, Fredrick M. Wigley7, Laura K. Hummers7, Marilyn Perry1, Carmen Pilar Simeon8, Patricia Carriera9, Norberto Ortego-Centeno10, Miguel Gonzalez-Gay11, the Spanish Scleroderma Group12 and Javier Martin13, 1University of Texas Health Science Center at Houston, Houston, TX, 2UT M. D. Anderson Cancer Center, Houston, TX, 3Consejo Superior de Investigaciones Científicas (CSIC), Armilla (Granada), Spain, 4Instituto de Parasitología y Biomedicina López-Neyra, IPBLN-CSIC, Armilla (Granada), Spain, 5Feinstein Institute Medical Reschearch, Manhasset, NY, 6Feinstein Institute Med Rsch, Manhasset, NY, 7Johns Hopkins University, Baltimore, MD, 8Hospital Valle de Hebron, Barcelona, Spain, 9Madrid, Spain, 10Hospital Clínico San Cecilio, Granada, Spain, 11Hospital Marques De Valdecilla, Santander, Spain, 12Granada, Spain, 13Instituto de Parasitologia y Biomedicina Lopez-Neyra (CSIC), Granada, Spain
Hospital Miguel Servet
Biologics use in SLE in 23 Centers - Data from the International Registry for Biologics In SLE (IRBIS)
R.F. van Vollenhoven1, Søren Jacobsen2, Daniel Wallace3, John G. Hanly4, Michelle Petri5, David A. Isenberg6, Sasha Bernatsky7, Sang-Cheol Bae8, Manuel Ramos-Casals9, Guillermo Ruiz-Irastorza10, Francisco J. García-Hernández11, Luis Saez12, José Luis Callejas13, Javier Rascón14, Enrique de Ramón15, Mª Mar Ayala-Gutiérrez15, Maite Camps15, Melinda Mild16, Murat Inanç17, Bahar Artim-Esen17, Rosalind Ramsey-Goldman18, Christine A. Peschken19, Danilo Squatrito20, László Kovács21, Andrea Doria22, Zoltan Szekanecz23, Elisa Gremese24 and Emilia I. Sato25, 1Karolinska University Hospital, Stockholm, Sweden, 2Copenhagen University Hospital, Copenhagen, Denmark, 3Cedars-Sinai/UCLA, Los Angeles, CA, 4Dalhousie University and Capital Health, Halifax, NS, 5Johns Hopkins Hospital, Baltimore, MD, 6University College London, London, United Kingdom, 7McGill UHC/RVH, Montreal, QC, 8Hanyang University Hospital for Rheumatic Diseases, Seoul, South Korea, 9Hospital Clínic, Barcelona, Spain, 10Hospital de Cruces, Bizkaia, Spain, 11Hospital Virgen del Rocío, Sevilla, Spain, 12Hospital Miguel Servet, Zaragoza, Spain, 13Hospital San Cecilio, Granada, Spain, 14Hospital Son Dureta, Palma de Mallorca, Spain, 15Hospital Carlos Haya, Málaga, Spain, 16Karolinska Institutet, Stockholm, Sweden, 17Istanbul University, Istanbul Medical Faculty, Istanbul, Turkey, 18Northwestern University Feinberg School of Medicine, Chicago, IL, 19Univ of Manitoba, Winnipeg, MB, 20Careggi Hospital- Florence, Florence, Italy, 21University of Szeged, Szeged, Hungary, 22University of Padova, Padova, Italy, 23University of Debrecen Medical and Health Sciences Center, Debrecen, Hungary, 24Rheumatology Unit, Catholic University, Roma, Italy, 25Escola Paulista de Medicina - Universidade Federal de São Paulo, Sao Paulo, Brazil
Hospital Militar
Clinical and Genetic Features of Autoinflammatory Syndromes in Hispanic Patients: The Chilean Experience
Cristian Vergara1, Arturo Borzutzky1, Miguel A. Gutierrez1, Sergio Iacobelli1, Eduardo Talesnik1, Maria Eugenia Martinez1, Lilith Stange1, Javier Basualdo2, Viviana Maluje3, Renato Jimenez4, Elena Jarpa5, Roberto Wiener6, Javier Tinoco6, Juan I. Arostegui7, Jordi Yague7 and Manuel Alvarez-Lobos1, 1Pontificia Universidad Catolica de Chile, Santiago, Chile, 2Universidad de Chile, Santiago, Chile, 3Hospital FACH, Santiago, Chile, 4Hospital Gustavo Fricke, Valparaiso, Chile, 5Hospital Naval Almirante Nef, Vina Del Mar, Chile, 6Hospital Militar, Santiago, Chile, 7Hospital Clínic / IDIBAPS, Barcelona, Spain
Hospital Mocel
Low Disease Activity or Remission Induction with Etanercept 50 Mg and Methotrexate in Moderately Active Rheumatoid Arthritis: Maintenance of Response and Safety of Etanercept 50 Mg, 25 Mg, or Placebo in Combination with Methotrexate in a Randomized Double-Blind Study
Josef S. Smolen1, Elena Ilivanova2, Stephen Hall3, Fedra Irazoque-Palazuelos4, Min-Chan Park5, Sameer Kotak6, Constance Hammond6, Ronald Pedersen6, Annette Szumski6, Andrew S. Koenig6 and Bonnie Vlahos6, 1Medical University of Vienna and Hietzing Hospital, Vienna, Austria, 2Leningradskaya Regional Clinical Hospital, St.Petersburg, Russia, 3Emeritus Research, Malvern East, Australia, 4Hospital Mocel, Mexico City, Mexico, 5Yonse University College of Medicine, Seoul, South Korea, 6Pfizer Inc., Collegeville, PA
Hospital Moises Broggi
Changes in Psychological Status in Patients with Chronic Spondyloarthropathy Treated with Infliximab
Rosa M. Morlà1, Hector Corominas2, M. V. Hernandez3, Mireia Moreno4, Miquel Sala5, Vera Ortiz-Santamaria6, Patricia Reyner6, Vicente Torrente-Segarra Jr.7, Agusti Sellas Fernandez8, Georgina Salvador9, Elena Sirvent10, Cristina Masuet11 and Xavier Juanola-Roura12, 1Hospital Sta Tecla, Tarragona, Spain, 2Hospital Moises Broggi, Barcelona, 3Hospital Clinic of Barcelona, Barcelona, Spain, 4Servei de Reumatologia, Sabadell, Spain, 5Rheumatology Unit, Figueres, Spain, 6Unitat de Reumatologia, Spain, 7Hospital General de Hospitalet, Barcelona, Spain, 8Senior Consultant, Barcelon, Spain, 9Hospital Mutua de Terrassa. Barcelona, Barcelona, Spain, 10Hospital de Sant Boi, 11Hospital de Bellvitge, Hospitalet de LLobregat, Spain, 12Hospital Universitario de Bellvitge, Barcelona, Spain
Hospital Monte Sinai , BIOMAB IPS
Early Rheumatoid Arthritis in Latin America. Low Socioeconomic Status Relates to High Disease Activity At Baseline
Loreto Massardo, Catholic University of Chile, Santiago 114-D, Chile, Bernardo A. Pons-Estel, Hospital Provincial, Rosario, Argentina, Mario H. Cardiel, Hospital General "Dr. Miguel Silva", Morelia, Mexico, Claudio Galarza-Maldonado, Hospital Monte Sinai , BIOMAB IPS, Cuenca, Ecuador, Mónica P. Sacnun, Hosp. Provincial, Rosario, Argentina, Enrique R. Soriano, Hospital Italiano de Buenos Aires, Buenos Aires, Argentina, Ieda Laurindo, Universidade de São Paulo, Sao Paulo, Brazil, Eduardo M. Acevedo-Vásquez, Hospital Nacional “Guillermo Almenara Irigoyen”, Lima, Peru, Carlo V. Caballero-Uribe, Continential Med Ctr, Barranquilla, Colombia, Oslando Padilla, Pontificia Universidad Catolica de Chile, Santiago, Chile, Marlene Guibert-Toledano, Centro de Investigaciones Médico Quirúrgicas, Habana, Ciudad Habana, Cuba, Rubén A. Montufar Guardado, Instituto Salvadoreño del Seguro Social, San Salvador, El Salvador, Sergio H. Jacobelli, Universidad Catolica de Chile, Santiago, Chile and Daniel E. Furst, UCLA Medical School, Los Angeles, CA
Hospital Mutua de Terrassa. Barcelona
A Significant Proporcion of Patients with Palindromic Rheumatism and Positive Anti-Citrulinated Protein Antibodies Do Not evolve to Rheumatoid Arthritis after  a Long Term Follow-up
S. Cabrera1, J. A. Gomez- Puerta1, M. V. Hernandez1, V. Ruiz -Esquide1, Georgina Salvador2, M.E. Gomez -Caballero1, J. Ramirez1, J. D. Cañete1 and R. Sanmarti1, 1Hospital Clinic of Barcelona, Barcelona, Spain, 2Hospital Mutua de Terrassa. Barcelona, Barcelona, Spain

Changes in Psychological Status in Patients with Chronic Spondyloarthropathy Treated with Infliximab
Rosa M. Morlà1, Hector Corominas2, M. V. Hernandez3, Mireia Moreno4, Miquel Sala5, Vera Ortiz-Santamaria6, Patricia Reyner6, Vicente Torrente-Segarra Jr.7, Agusti Sellas Fernandez8, Georgina Salvador9, Elena Sirvent10, Cristina Masuet11 and Xavier Juanola-Roura12, 1Hospital Sta Tecla, Tarragona, Spain, 2Hospital Moises Broggi, Barcelona, 3Hospital Clinic of Barcelona, Barcelona, Spain, 4Servei de Reumatologia, Sabadell, Spain, 5Rheumatology Unit, Figueres, Spain, 6Unitat de Reumatologia, Spain, 7Hospital General de Hospitalet, Barcelona, Spain, 8Senior Consultant, Barcelon, Spain, 9Hospital Mutua de Terrassa. Barcelona, Barcelona, Spain, 10Hospital de Sant Boi, 11Hospital de Bellvitge, Hospitalet de LLobregat, Spain, 12Hospital Universitario de Bellvitge, Barcelona, Spain
Hospital Nacional “Guillermo Almenara Irigoyen”
Early Rheumatoid Arthritis in Latin America. Low Socioeconomic Status Relates to High Disease Activity At Baseline
Loreto Massardo, Catholic University of Chile, Santiago 114-D, Chile, Bernardo A. Pons-Estel, Hospital Provincial, Rosario, Argentina, Mario H. Cardiel, Hospital General "Dr. Miguel Silva", Morelia, Mexico, Claudio Galarza-Maldonado, Hospital Monte Sinai , BIOMAB IPS, Cuenca, Ecuador, Mónica P. Sacnun, Hosp. Provincial, Rosario, Argentina, Enrique R. Soriano, Hospital Italiano de Buenos Aires, Buenos Aires, Argentina, Ieda Laurindo, Universidade de São Paulo, Sao Paulo, Brazil, Eduardo M. Acevedo-Vásquez, Hospital Nacional “Guillermo Almenara Irigoyen”, Lima, Peru, Carlo V. Caballero-Uribe, Continential Med Ctr, Barranquilla, Colombia, Oslando Padilla, Pontificia Universidad Catolica de Chile, Santiago, Chile, Marlene Guibert-Toledano, Centro de Investigaciones Médico Quirúrgicas, Habana, Ciudad Habana, Cuba, Rubén A. Montufar Guardado, Instituto Salvadoreño del Seguro Social, San Salvador, El Salvador, Sergio H. Jacobelli, Universidad Catolica de Chile, Santiago, Chile and Daniel E. Furst, UCLA Medical School, Los Angeles, CA
Hospital Naval Almirante Nef
Clinical and Genetic Features of Autoinflammatory Syndromes in Hispanic Patients: The Chilean Experience
Cristian Vergara1, Arturo Borzutzky1, Miguel A. Gutierrez1, Sergio Iacobelli1, Eduardo Talesnik1, Maria Eugenia Martinez1, Lilith Stange1, Javier Basualdo2, Viviana Maluje3, Renato Jimenez4, Elena Jarpa5, Roberto Wiener6, Javier Tinoco6, Juan I. Arostegui7, Jordi Yague7 and Manuel Alvarez-Lobos1, 1Pontificia Universidad Catolica de Chile, Santiago, Chile, 2Universidad de Chile, Santiago, Chile, 3Hospital FACH, Santiago, Chile, 4Hospital Gustavo Fricke, Valparaiso, Chile, 5Hospital Naval Almirante Nef, Vina Del Mar, Chile, 6Hospital Militar, Santiago, Chile, 7Hospital Clínic / IDIBAPS, Barcelona, Spain
Hospital Nossa Senhora da Conceição
Periungueal Capillaroscopy Using Conventional Dermoscopy: Easily Available Method and Simple to Perform During the Regular Office Consult in Patients with Systemic Sclerosis
Nicolle Mazzotti1, Claiton Brenol1, Markus Bredemeier2, João Carlos T. Brenol1, Ricardo M. Xavier1 and Tania Cestari1, 1Universidade Federal do Rio Grande do Sul, Porto Alegre, Brazil, 2Hospital Nossa Senhora da Conceição, Porto Alegre, Brazil
Hospital Ntra. Sra. de la Esperanza
Tofacitinib (CP-690,550), An Oral Janus Kinase Inhibitor, or Adalimumab Versus Placebo in Patients with Rheumatoid Arthritis on Background Methotrexate: A Phase 3 Study
R.F. van Vollenhoven1, R. M. Fleischmann2, S. B. Cohen3, E. B. Lee4, G. Meijide5, S. Wagner6, S. Forejtova7, S. H. Zwillich8, D. Gruben8, T. Koncz9, G. Wallenstein8, S. Krishnaswami8, J. D. Bradley8, B. Wilkinson8 and the ORAL Standard investigators10, 1Karolinska Institute, Stockholm, Sweden, 2Metroplex Clinical Research Center, Dallas, TX, 3Metroplex Clinical Research Centre, Dallas, TX, 4Seoul National University, Seoul, South Korea, 5Hospital Ntra. Sra. de la Esperanza, Santiago de Compostela, Spain, 6Internistische Schwerpunktpraxis für Rheumatologie, Halle, Germany, 7Revmatologicky ustav no 5, Prague, Czech Republic, 8Pfizer Inc., Groton, CT, 9Pfizer Inc., New York, NY, 10Groton, CT
Hospital of Southern Norway
The Epidemiology of Low and High Energy Distal Radius Fracture in Middle-Aged and Elderly Men and Women in Southern Norway
Andreas P. Diamantopoulos1, Gudrun Rohde1, Inger M. Skoie1, Irene Johnsrud1, Marc Hochberg2 and Glenn Haugeberg1, 1Hospital of Southern Norway, Kristiansand, Norway, 2University of Maryland School of Medicine, Baltimore, MD
Hospital of Vendsyssel/Ålborg University
The Melanocortin System: A New and Important Actor on the Scene of Systemic Sclerosis
Grethe N. Andersen, Hospital of Vendsyssel/Ålborg University, Hjørring, Denmark, Olga Nagaeva, University of Umeå, Umeå, Sweden, Lucia Mincheva-Nilsson, University of Umeå, Sweden and Jarl E.S. Wikberg, Department of Pharmaceutical Pharmacology, Uppsala, Sweden
Hospital Padilla
Work Disability Is Related to the Presence of Arthritis, Not to a Specific Diagnosis
Hernan Maldonado Ficco1, Rodolfo Perez Alamino1, Fernando Dal Pra1, Veronica Lencina1, Luciana Casalla2, Mariana Benegas2, Oscar Rillo3, Alberto Berman4, Ana Lucía Barbaglia4, Veronica Bellomio5, Francisco Caeiro6, Josefina Marcos7, Juan Carlos Marcos7, Antonio Catalan Pellet8, Rodrigo Garcia Salinas8, Sergio Paira9, Federico Ceccato9, Enrique Soriano10, Zaida Bendran10, Gabriela Salvatierra11 and Gustavo Citera1, 1Instituto de Rehabilitación Psicofísica, Buenos Aires, Argentina, 2Hospital Tornu, Buenos Aires, Argentina, 3Hospital Sirio Libanes, Buenos Aires, Argentina, 4Hospital Padilla, Tucuman, Argentina, 5Consultorio, Tucuman, Argentina, 6Hospital Privado de Cordoba, Cordoba, Argentina, 7Hospital San Martin, La Plata, Argentina, 8Hospital Rivadiavia, Buenos Aires, Argentina, 9Hospital Jose Maria Cullen, Santa Fe, Argentina, 10Hospital Italiano, Buenos Aires, Argentina, 11Centro de enfermedades Reumaticas, Santiago Del Estero, Argentina

A Phase 2 Study of Multiple Subcutaneous Doses of LY2439821, An Anti-IL-17 Monoclonal Antibody, in Patients with Rheumatoid Arthritis in Two Populations: Naïve to Biologic Therapy or Inadequate Responders to Tumor Necrosis Factor Alpha Inhibitors
Mark C. Genovese1, Maria W. Greenwald2, Chul Soo Cho3, Alberto Berman4, Ling Jin5, Gregory Cameron6, Li Xie5, Daniel Braun5, Subhashis Banerjee5 and Laura Warner7, 1Stanford University, Palo Alto, CA, 2Desert Medical Advances, Palm Desert, CA, 3St Marys Hospital, Seoul, 4Hospital Padilla, Tucuman, Argentina, 5Eli Lilly and Company, Indianapolis, IN, 6Eli Lily and Company, Indianapolis, IN, 7i3 Statprobe, Indianapolis, IN
Hospital Parc Tauli
The New EULAR/ACR Classification ACPA Cutoff Levels Are Markers of Poor Radiological Outcome in Early Rheumatoid Arthritis
Jose Alfredo Gomez Puerta1, Virginia Ruiz Esquide1, M. V. Hernandez1, Eduard Graell2, Sonia Cabrera3, M. J. Gómara4, Juan D. Cañete5, Isabel Haro4 and R. Sanmarti1, 1Hospital Clinic of Barcelona, Barcelona, Spain, 2Hospital Parc Tauli, Sabadell, Spain, 3Hospital Clinic of Barcelona., Barcelona, Spain, 4IQAC-CSIC, Barcelona, Spain, 5Hospital Clínic de Barcelona, IDIBAPS, Barcelona, Spain

Smoking Impact on Radiographic Progression in An Early Rheumatoid Arthritis Cohort
Virginia Ruiz-Esquide1, Jose Alfredo Gomez Puerta2, S. Cabrera1, J. D. Cañete3, M. V. Hernandez2, Eduard Graell4, Guadalupe Ercilla1, Odette Viñas1, M. J. Gómara5, Isabel Haro5 and Raimon Sanmarti2, 1Hospital Clinic of Barcelona., Barcelona, Spain, 2Hospital Clinic of Barcelona, Barcelona, Spain, 3Hospital Clínic de Barcelona,, Barcelona, Spain, 4Hospital Parc Tauli, Sabadell, Spain, 5IQAC-CSIC, Barcelona, Spain
Hospital Peset
High Dose Intravenous Methylprednisolone Induces Rapid Improvement In Severe Uveitis: A Multicenter Study
Carmen Bejerano1, Ricardo Blanco1, Emma Beltrán2, Alejandro Fonollosa3, Olga Maiz4, Ana Blanco-Esteban4, Miguel Cordero5, Inés Pérez-Martín6, Joaquín Cañal6, Juan Ventosa6 and Miguel Angel González-Gay6, 1Hospital Universitario Marqués de Valdecilla-IFIMAV, Santander, Spain, 2Hospital Peset, Valencia, Spain, 3Hospital de Cruces, Barakaldo-Bilbao, Spain, 4Hospital Donostia, San Sebastian, Spain, 5Hospital León, León, Spain, 6Hospital Universitario Marqués de Valdecilla. IFIMAV, Santander, Spain
Hospital Privado
The Protective Effect of Antimalarials On Thrombovascular Events In Latin American Systemic Lupus Erythematosus Patients
Guillermo J. Pons-Estel, Servicio de Enfermedades Autoinmunes, Hospital Clìnic Barcelona, Barcelona, Spain, Graciela S. Alarcón, University of Alabama at Birmingham, Birmingham, AL, Daniel Wojdyla, Universidad Nacional de Rosario, Argentina, Rosario, Argentina, Ana I. Marcos, Hospital Interzonal General de Agudos “General San Martin, La Plata, La Plata, Argentina, Alejandro J. Alvarellos, Hospital Privado, Cordoba, Argentina, Antonio A. Iglesias-Gamarra, Universidad Nacional, Bogota, Colombia, Maria H. Esteva-Spinetti, Centro Clinico San Cristobal, San Cristobal, Venezuela, Lilian Costallat, Faculdade de Ciencias Medicas, Universidade Estadual de Campinas, Campinas, Brazil, Nilzio A. Silva, Faculdade de Medicina, Universidade Federal de Goias, Goiania, Brazil, Gloria Vázquez, Universidad de Antioquia, Hospital Universitario “San Vicente de Paul”, Medellín, Colombia, Maria Loreto Massardo, Catholic University of Chile, Santiago, Chile, Marlene Guibert-Toledano, Centro de Investigaciones Médico Quirúrgicas, Habana, La Habana, Cuba, Guillermo F. Huerta-Yáñez, Hospital de Especialidades Miguel Hidalgo, Aguascalientes, Mexico, Mariano Cucho-Venegas, Almenara Hospital IPSs, Lima, Peru and Bernardo Pons-Estel, Hospital Provincial de Rosario, Rosario, Argentina

Prevalence and Correlates of Metabolic Syndrome in Patients with Rheumatoid Arthritis
Maria Haye Salinas1, Ana M. Bertoli2, Francisco Caeiro3, Luis Lema4, Veronica Bellomio5, Santiago Aguero6, Federico Ceccato7, Carla Saucedo8, Javier Rosa8, R. Quintana9, Marcela Schmid10, Walter Spindler11, Natalia Tamborenea12, Sergio Paira7, Bernardo Pons Estel13, Alberto J. Spindler14, Enrique R. Soriano8, Alejandro J. Alvarellos15 and Veronica Saurit16, 1Hospital Privado, Córdoba, Argentina, 2Instituto Reumatológico Strusberg, Cordoba, Cordoba, Argentina, 3Hospital Privado de Cordoba, Cordoba, Argentina, 4Instituto Modelo de Cardiologia, Cordoba, Argentina, 5Consultorio, Tucuman, Argentina, 6Centro de Rehabilitación II, Catamarca, Argentina, 7Hospital Jose Maria Cullen, Santa Fe, Argentina, 8Rheumatology Unit, Internal Medical Services, Hospital Italiano de Buenos Aires, Buenos Aires, Argentina, 9Hospital Provincial, Rosario, Argentina, 10Hospital Cullen, Santa Fe, Argentina, 11Centro Medico Privado, Tucuman, Argentina, 12Consultorio, Buenos Aires, Argentina, 13Sanatorio Parque, Rosario, Argentina, 14Universidad Nacional Tucumán, Yerba Buena Tucuman, Argentina, 15Hospital Privado, Cordoba, Argentina, 16Hospital Privado Córdoba, Córdoba, Argentina
Hospital Privado Córdoba
Prevalence and Correlates of Metabolic Syndrome in Patients with Rheumatoid Arthritis
Maria Haye Salinas1, Ana M. Bertoli2, Francisco Caeiro3, Luis Lema4, Veronica Bellomio5, Santiago Aguero6, Federico Ceccato7, Carla Saucedo8, Javier Rosa8, R. Quintana9, Marcela Schmid10, Walter Spindler11, Natalia Tamborenea12, Sergio Paira7, Bernardo Pons Estel13, Alberto J. Spindler14, Enrique R. Soriano8, Alejandro J. Alvarellos15 and Veronica Saurit16, 1Hospital Privado, Córdoba, Argentina, 2Instituto Reumatológico Strusberg, Cordoba, Cordoba, Argentina, 3Hospital Privado de Cordoba, Cordoba, Argentina, 4Instituto Modelo de Cardiologia, Cordoba, Argentina, 5Consultorio, Tucuman, Argentina, 6Centro de Rehabilitación II, Catamarca, Argentina, 7Hospital Jose Maria Cullen, Santa Fe, Argentina, 8Rheumatology Unit, Internal Medical Services, Hospital Italiano de Buenos Aires, Buenos Aires, Argentina, 9Hospital Provincial, Rosario, Argentina, 10Hospital Cullen, Santa Fe, Argentina, 11Centro Medico Privado, Tucuman, Argentina, 12Consultorio, Buenos Aires, Argentina, 13Sanatorio Parque, Rosario, Argentina, 14Universidad Nacional Tucumán, Yerba Buena Tucuman, Argentina, 15Hospital Privado, Cordoba, Argentina, 16Hospital Privado Córdoba, Córdoba, Argentina
Hospital Privado de Cordoba
Prevalence and Correlates of Metabolic Syndrome in Patients with Rheumatoid Arthritis
Maria Haye Salinas1, Ana M. Bertoli2, Francisco Caeiro3, Luis Lema4, Veronica Bellomio5, Santiago Aguero6, Federico Ceccato7, Carla Saucedo8, Javier Rosa8, R. Quintana9, Marcela Schmid10, Walter Spindler11, Natalia Tamborenea12, Sergio Paira7, Bernardo Pons Estel13, Alberto J. Spindler14, Enrique R. Soriano8, Alejandro J. Alvarellos15 and Veronica Saurit16, 1Hospital Privado, Córdoba, Argentina, 2Instituto Reumatológico Strusberg, Cordoba, Cordoba, Argentina, 3Hospital Privado de Cordoba, Cordoba, Argentina, 4Instituto Modelo de Cardiologia, Cordoba, Argentina, 5Consultorio, Tucuman, Argentina, 6Centro de Rehabilitación II, Catamarca, Argentina, 7Hospital Jose Maria Cullen, Santa Fe, Argentina, 8Rheumatology Unit, Internal Medical Services, Hospital Italiano de Buenos Aires, Buenos Aires, Argentina, 9Hospital Provincial, Rosario, Argentina, 10Hospital Cullen, Santa Fe, Argentina, 11Centro Medico Privado, Tucuman, Argentina, 12Consultorio, Buenos Aires, Argentina, 13Sanatorio Parque, Rosario, Argentina, 14Universidad Nacional Tucumán, Yerba Buena Tucuman, Argentina, 15Hospital Privado, Cordoba, Argentina, 16Hospital Privado Córdoba, Córdoba, Argentina

Work Disability Is Related to the Presence of Arthritis, Not to a Specific Diagnosis
Hernan Maldonado Ficco1, Rodolfo Perez Alamino1, Fernando Dal Pra1, Veronica Lencina1, Luciana Casalla2, Mariana Benegas2, Oscar Rillo3, Alberto Berman4, Ana Lucía Barbaglia4, Veronica Bellomio5, Francisco Caeiro6, Josefina Marcos7, Juan Carlos Marcos7, Antonio Catalan Pellet8, Rodrigo Garcia Salinas8, Sergio Paira9, Federico Ceccato9, Enrique Soriano10, Zaida Bendran10, Gabriela Salvatierra11 and Gustavo Citera1, 1Instituto de Rehabilitación Psicofísica, Buenos Aires, Argentina, 2Hospital Tornu, Buenos Aires, Argentina, 3Hospital Sirio Libanes, Buenos Aires, Argentina, 4Hospital Padilla, Tucuman, Argentina, 5Consultorio, Tucuman, Argentina, 6Hospital Privado de Cordoba, Cordoba, Argentina, 7Hospital San Martin, La Plata, Argentina, 8Hospital Rivadiavia, Buenos Aires, Argentina, 9Hospital Jose Maria Cullen, Santa Fe, Argentina, 10Hospital Italiano, Buenos Aires, Argentina, 11Centro de enfermedades Reumaticas, Santiago Del Estero, Argentina
Hospital Provincial
Prevalence and Correlates of Metabolic Syndrome in Patients with Rheumatoid Arthritis
Maria Haye Salinas1, Ana M. Bertoli2, Francisco Caeiro3, Luis Lema4, Veronica Bellomio5, Santiago Aguero6, Federico Ceccato7, Carla Saucedo8, Javier Rosa8, R. Quintana9, Marcela Schmid10, Walter Spindler11, Natalia Tamborenea12, Sergio Paira7, Bernardo Pons Estel13, Alberto J. Spindler14, Enrique R. Soriano8, Alejandro J. Alvarellos15 and Veronica Saurit16, 1Hospital Privado, Córdoba, Argentina, 2Instituto Reumatológico Strusberg, Cordoba, Cordoba, Argentina, 3Hospital Privado de Cordoba, Cordoba, Argentina, 4Instituto Modelo de Cardiologia, Cordoba, Argentina, 5Consultorio, Tucuman, Argentina, 6Centro de Rehabilitación II, Catamarca, Argentina, 7Hospital Jose Maria Cullen, Santa Fe, Argentina, 8Rheumatology Unit, Internal Medical Services, Hospital Italiano de Buenos Aires, Buenos Aires, Argentina, 9Hospital Provincial, Rosario, Argentina, 10Hospital Cullen, Santa Fe, Argentina, 11Centro Medico Privado, Tucuman, Argentina, 12Consultorio, Buenos Aires, Argentina, 13Sanatorio Parque, Rosario, Argentina, 14Universidad Nacional Tucumán, Yerba Buena Tucuman, Argentina, 15Hospital Privado, Cordoba, Argentina, 16Hospital Privado Córdoba, Córdoba, Argentina

Early Rheumatoid Arthritis in Latin America. Low Socioeconomic Status Relates to High Disease Activity At Baseline
Loreto Massardo, Catholic University of Chile, Santiago 114-D, Chile, Bernardo A. Pons-Estel, Hospital Provincial, Rosario, Argentina, Mario H. Cardiel, Hospital General "Dr. Miguel Silva", Morelia, Mexico, Claudio Galarza-Maldonado, Hospital Monte Sinai , BIOMAB IPS, Cuenca, Ecuador, Mónica P. Sacnun, Hosp. Provincial, Rosario, Argentina, Enrique R. Soriano, Hospital Italiano de Buenos Aires, Buenos Aires, Argentina, Ieda Laurindo, Universidade de São Paulo, Sao Paulo, Brazil, Eduardo M. Acevedo-Vásquez, Hospital Nacional “Guillermo Almenara Irigoyen”, Lima, Peru, Carlo V. Caballero-Uribe, Continential Med Ctr, Barranquilla, Colombia, Oslando Padilla, Pontificia Universidad Catolica de Chile, Santiago, Chile, Marlene Guibert-Toledano, Centro de Investigaciones Médico Quirúrgicas, Habana, Ciudad Habana, Cuba, Rubén A. Montufar Guardado, Instituto Salvadoreño del Seguro Social, San Salvador, El Salvador, Sergio H. Jacobelli, Universidad Catolica de Chile, Santiago, Chile and Daniel E. Furst, UCLA Medical School, Los Angeles, CA
Hospital Provincial de Rosario
The Protective Effect of Antimalarials On Thrombovascular Events In Latin American Systemic Lupus Erythematosus Patients
Guillermo J. Pons-Estel, Servicio de Enfermedades Autoinmunes, Hospital Clìnic Barcelona, Barcelona, Spain, Graciela S. Alarcón, University of Alabama at Birmingham, Birmingham, AL, Daniel Wojdyla, Universidad Nacional de Rosario, Argentina, Rosario, Argentina, Ana I. Marcos, Hospital Interzonal General de Agudos “General San Martin, La Plata, La Plata, Argentina, Alejandro J. Alvarellos, Hospital Privado, Cordoba, Argentina, Antonio A. Iglesias-Gamarra, Universidad Nacional, Bogota, Colombia, Maria H. Esteva-Spinetti, Centro Clinico San Cristobal, San Cristobal, Venezuela, Lilian Costallat, Faculdade de Ciencias Medicas, Universidade Estadual de Campinas, Campinas, Brazil, Nilzio A. Silva, Faculdade de Medicina, Universidade Federal de Goias, Goiania, Brazil, Gloria Vázquez, Universidad de Antioquia, Hospital Universitario “San Vicente de Paul”, Medellín, Colombia, Maria Loreto Massardo, Catholic University of Chile, Santiago, Chile, Marlene Guibert-Toledano, Centro de Investigaciones Médico Quirúrgicas, Habana, La Habana, Cuba, Guillermo F. Huerta-Yáñez, Hospital de Especialidades Miguel Hidalgo, Aguascalientes, Mexico, Mariano Cucho-Venegas, Almenara Hospital IPSs, Lima, Peru and Bernardo Pons-Estel, Hospital Provincial de Rosario, Rosario, Argentina
Hospital Puerta de Hierro
The IRF7 Region Is Associated with Anti-Centromere Autoantibody Production in Systemic Sclerosis Patients
F. David Carmona1, Ramana Gutala2, Carmen P. Simeón3, Patricia E. Carreira4, Norberto Ortego-Centeno5, Esther Vicente-Rabaneda6, Francisco J. García-Hernández7, Paloma García de la Peña8, Mónica Fernández-Castro9, Lina Martínez-Estupiñán10, María-Victoria Egurbide11, Spanish Scleroderma Group, Betty P. Tsao13, Pravitt R. Gourh14, Sandeep K. Agarwal15, Shervin Assassi16, Maureen D. Mayes15, Frank C. Arnett15, Filemon K. Tan15 and Javier Martín17, 1Consejo Superior de Investigaciones Científicas, Armilla (Granada), Spain, 2The University of Texas Health Science Center, Houston, TX, 3Hospital Valle de Hebron, Barcelona, Spain, 4Instituto de Investigación Hospital 12 de Octubre (I+12), Madrid, Spain, 5Hospital Clínico San Cecilio, Granada, Spain, 6Hospital de la Princesa, Madrid, Spain, 7Hospital Virgen del Rocío, Sevilla, Spain, 8Hospital Universitario Madrid Norte Sanchinarro, Madrid, Spain, 9Hospital Puerta de Hierro, Madrid, Spain, 10Gregorio Marañón Hospital, Madrid, Spain, 11Hospital de Cruces, UPV/EHU, Barakaldo, Spain, Barakaldo, Spain, 12David Geffen School of Medicine University of California Los Angeles, Los Angeles, CA, 13UTHSC-Houston Medical School, Houston, TX, 14University of Texas Health Science Center at Houston, Houston, TX, 15Univ of Texas Health Science, Houston, TX, 16Consejo Superior de Investigaciones Científicas, Granada, Spain
Hospital Ramon y Cajal
Adalimumab in 107 Refractory Uveitis: A Multicenter Study
Orlando Pompei1, Ricardo Blanco2, Manuel Diaz-llopis3, David Salom3, Carmen Garcia-Vicuña4, Miguel Cordero-Coma5, Gabriela Ortega-Larrocea6, Norberto Ortego-Centeno7, Marta Suarez-de-Figueroa8, J. Carlos Fernandez-Cid9, Alejandro Fonollosa10, Angel M. Garcia-Aparicio11, Jose M. Benítez-del-Castillo12, Jose L. Olea13 and J. Fernando Arevalo14, 1Hospital Universitario Marqués de Valdecilla. IFIMAV, Santander, Spain, 2Hospital Universitario Marqués de Valdecilla-IFIMAV, Santander, Spain, 3La Fe University Hospital of Valencia, Valencia, Spain, 4Hospital Sant Joan de Déu, Barcelona, Spain, 5Hospital de León, León, Spain, 6National Institute of Rehabilitation, D.F Mexico, Mexico, 7Hospital Clínico San Cecilio, Granada, Spain, 8Hospital Ramon y Cajal, Madrid, Spain, 9Hospital de Pontevedra, Pontevedra, Spain, 10Hospital de Cruces, Bilbao, Spain, 11Hospital Virgen de la Salud, Toledo, Spain, 12Hospital Clínico San Carlos, Madrid, 13Hospital Son Dureta, Palma de Mallorca, Spain, 14Ophthalmology Clinic Center of Caracas, Caracas, Venezuela
Hospital Regional de Zona 110, Instituto Mexicano del Seguro Social (IMSS), Guadalajara, Jalisco, Mexico
R577X Alpha-Actinin 3 (ACTN3) polymorphism Is Associated with Inflammatory Myopathies in Mexican population 
Flavio Sandoval- Garcia1, Marcelo Petri2, Miguel A. Saavedra3, Claudia Cruz-Reyes4, Luis Jara-Quezada3, Ingrid Dávalos5, Mario Salazar-Páramo6, Ivan Gámez-Nava7, Laura Gonzalez-Lopez8, Trinidad García-Iglesias9, Esther Corona-Sánchez10, Soraya Zavaleta-Muñiz11, Raúl Vargas-Ramírez10, Jorge Aguilar Arreola12, Monica Vázquez-Del Mercado11 and Beatriz T. Martín-Márquez13, 1Instituto de Investigación en Reumatología y del Sistema Músculo Esquelético, Universidad de Guadalajara, Guadalajara, Jalisco, Mexico, Mexico, 2Universidad de Guadalajara, Guadalajara, Jalisco, Mexico, Mexico, 3Centro Medico La Raza Instituto Mexicano del Seguro Social Mexico D.F., México D.F., Mexico, 4Centro Medico La Raza Instituto Mexicano del Seguro Social Mexico D.F., Mexico D. F., Mexico, 5Departamento de Biologia Molecular y Genomica, Instituto de Genetica Humana, Centro Universitario de Ciencias de la Salud, Universidad de Guadalajara, Guadalajara, Jalisco, Mexico, Mexico, 6Departamento de Fisiología, Centro Universitario de Ciencias de la Salud, Universidad de Guadalajara, Guadalajara, Jalisco, Mexico, Mexico, 7Centro Médico Nacional de Occidente, IMSS, Guadalajara, Jalisco, México., Mexico, 8Hospital Regional de Zona 110, Instituto Mexicano del Seguro Social (IMSS), Guadalajara, Jalisco, Mexico, Guadalajara, Jalisco, Mexico, Mexico, 9Laboratorio de Inmunología, Centro Universitario de Ciencias de la Salud, Universidad de Guadalajara, Guadalajara, Jalisco, Mexico, Mexico, 10Instituto de Investigación en Reumatología y del Sistema Músculo Esquelético, Universidad de Guadalajara, Guadalajara, Jalisco, México, Mexico, 11Universidad de Guadalajara, Guadalajara, Jalisco, México, Mexico, 12Hospital Civil JIM, 13Universidad de Guadalajara, Gudalajara, Jalisco, México, Mexico
Hospital Regional Universitario Carlos Haya
Application of Combined Algorithms with Peripheral Bone Mineral Density (BMD) and Risk Indeces to Reduce the Requirement for Central Dual X-Ray Absorptometry (DXA)
María América López-Lasanta1, Francisco G. Jiménez-Núñez1, Carmen M. Romero-Barco1, Sara Manrique-Arija1, Verónica Rodriguez-García1, Miguel A. Descalzo2, Blanca Panero1, Jose Mancera Romero3, Silvia Mesa González3, Maria Carmen Ordóñez1, Inmaculada Ureña1, Manuel Rodríguez-Pérez1 and Antonio Fernandez-Nebro4, 1Hospital Regional Universitario Carlos Haya., Málaga, Spain, 2Spanish Society of Rheumatology, Madrid, Spain, 3Health Center "Ciudad Jardín", Malaga, Spain, 4Hospital Regional Universitario Carlos Haya, Málaga, Spain
Hospital Regional Universitario Carlos Haya.
Are Training Sessions Useful for Ultrasound Scan Evaluation of Synovitis In Rheumatoid Arthritis?
Andrés Ponce, Hospital General de Granollers, Granollers, Spain, Juan J. Alegre, Hospital Universitario Dr Peset, Valencia, Spain, Manuel Castaño, Hospital Universitario Virgen de la Arrixaca, Murcia, Spain, Ricardo Gutierrez-Polo, C.H. de Navarra, Pamplona, Spain, Francisco G. Jiménez-Núñez, Hospital Regional Universitario Carlos Haya., Malaga, Spain, María P. Macarrón, Hospital Clínico San Carlos, Madrid, Spain and Jesús Garrido, Facultad de Psicología.Universidad Autónoma de Madrid, Madrid, Spain

Application of Combined Algorithms with Peripheral Bone Mineral Density (BMD) and Risk Indeces to Reduce the Requirement for Central Dual X-Ray Absorptometry (DXA)
María América López-Lasanta1, Francisco G. Jiménez-Núñez1, Carmen M. Romero-Barco1, Sara Manrique-Arija1, Verónica Rodriguez-García1, Miguel A. Descalzo2, Blanca Panero1, Jose Mancera Romero3, Silvia Mesa González3, Maria Carmen Ordóñez1, Inmaculada Ureña1, Manuel Rodríguez-Pérez1 and Antonio Fernandez-Nebro4, 1Hospital Regional Universitario Carlos Haya., Málaga, Spain, 2Spanish Society of Rheumatology, Madrid, Spain, 3Health Center "Ciudad Jardín", Malaga, Spain, 4Hospital Regional Universitario Carlos Haya, Málaga, Spain
Hospital Rivadiavia
Work Disability Is Related to the Presence of Arthritis, Not to a Specific Diagnosis
Hernan Maldonado Ficco1, Rodolfo Perez Alamino1, Fernando Dal Pra1, Veronica Lencina1, Luciana Casalla2, Mariana Benegas2, Oscar Rillo3, Alberto Berman4, Ana Lucía Barbaglia4, Veronica Bellomio5, Francisco Caeiro6, Josefina Marcos7, Juan Carlos Marcos7, Antonio Catalan Pellet8, Rodrigo Garcia Salinas8, Sergio Paira9, Federico Ceccato9, Enrique Soriano10, Zaida Bendran10, Gabriela Salvatierra11 and Gustavo Citera1, 1Instituto de Rehabilitación Psicofísica, Buenos Aires, Argentina, 2Hospital Tornu, Buenos Aires, Argentina, 3Hospital Sirio Libanes, Buenos Aires, Argentina, 4Hospital Padilla, Tucuman, Argentina, 5Consultorio, Tucuman, Argentina, 6Hospital Privado de Cordoba, Cordoba, Argentina, 7Hospital San Martin, La Plata, Argentina, 8Hospital Rivadiavia, Buenos Aires, Argentina, 9Hospital Jose Maria Cullen, Santa Fe, Argentina, 10Hospital Italiano, Buenos Aires, Argentina, 11Centro de enfermedades Reumaticas, Santiago Del Estero, Argentina
Hospital Saint Joseph Saint Luc
Rapid Surges of Anti-dsDNA Titers Predict Severe Clinical Flares in Systemic Lupus Erythematosus
Nancy Pan1, Isabelle Amigues2, Rolando Duculan3, Faiza Aziz4, Stephen L. Lyman1, Mary K. Crow1 and Kyriakos A. Kirou1, 1Hospital for Special Surgery, New York, NY, 2Hospital Saint Joseph Saint Luc, Paris, France, 3Mary Kirkland Center for Lupus Research-Hospital for Special Surgery, New York, NY, 4Interfaith Medical Center, Brooklyn, NY
Hospital Saint-Louis
Churg–Strauss Syndrome: Description and Long-Term Follow-up of the 383 Patients Enrolled In the FVSG Cohort
Christian Pagnoux1, Chloe Comarmond2, Mehdi Khellaf3, Jean-Francois Cordier4, Mohamed Hamidou5, Jean-Francois Viallard6, Francois Maurier7, Philippe Delaval8, Boris Bienvenu9, Xavier Puechal10, Olivier Aumaître11, Marc Ruivard12, Alain Le Quellec13, Ramiro Cevallos14, Olivier Fain15, Bertrand Godeau3, Raphaèle Seror2, Alfred Mahr16, Pascal Cohen17, Luc Mouthon18, Loic Guillevin19 and French Vasculitis Study Group (FVSG)*, 1University of Toronto, Toronto, ON, 2Referral Center for Necrotizing Vasculitides, Hôpital Cochin, AP–HP, Université Paris–Descartes, Paris, France, 3Service de médecine interne, Université Paris Est Créteil, AP-HP, Hôpital Mondor Créteil, France, Creteil, France, 4Division of Pneumology, Hôpital Louis-Pradel, Hospices Civils de Lyon, Lyon 1, Lyon, France, 5Service de médecine interne, Hôpital Universitaire de Nantes, Nantes, France, Nantes, France, 6Division of internal Medicine, Hôpital Haut-Lévêque, Université Victor Segalen – Bordeaux 2, Centre Hospitalier Universitaire de Bordeaux, Bordeaux, Bordeaux, France, 7Division of internal Medicine, CHR Metz, Metz, Metz, France, 8Division of Pneumology, Centre Hospitalier Régional Universitaire de Rennes, Rennes, Rennes, France, 9Division of Internal Medicine, Centre Hospitalier Régional Universitaire de Caen, Côte de Nacre, Caen, Caen, France, 10Le Mans General Hospital, Le Mans, France, 11Division of internal Medicine, Centre Hospitalier Universitaire, Hôpital Gabriel Montpied, Clermont–Ferrand, Clermont–Ferrand, France, 12Medicine, Centre Hospitalier Universitaire, Hôpital Gabriel Montpied, Clermont–Ferrand, Clermont–Ferrand, France, 13Division of internal Medicine, Hôpital Saint-Eloi, Centre Hospitalier Universitaire de Montpellier, Montpellier, Montpellier, France, 14CH Compiegne, Compiegne, France, 15Service de médecine interne, Université Paris 13, AP-HP, Hôpital Jean Verdier, 93140, Bondy, France., Bondy, France, 16Hospital Saint-Louis, Paris, France, 17Service de médecine interne, Centre de Références des Vascularites, Université Paris Descartes, APHP, Hôpital Cochin, 75005 Paris, France., Paris, France, 18Hopital Cochim, Paris, France, 19Cochin University Hospital, Paris, France

Descriptive Epidemiology of Granulomatosis with Polyangitis (Wegener’s), Microscopic Polyangitis, Polyarteritis Nodosa and Goodpasture’s Syndrome in the United States
Martin M. Crane, GlaxoSmithKline, Research Triangle, NC, Vincent X. Rabatin, GlaxoSmithKline, Research Triangle Park, NC and Alfred Mahr, Hospital Saint-Louis, Paris, France

Exploration of Male Gender in Heterogeneity of Association Between HLA-B51/B5 and Behçet’s Disease Using Mixture Models
Michael P. LaValley1, Hailong Cheng2, Mathilde de Menthon3 and Alfred Mahr3, 1Boston University School of Public Health, Boston, MA, 2Sunovion Pharmaceuticals Inc., Marlborough, MA, 3Hospital Saint-Louis, Paris, France
Hospital San Cecilio
Biologics use in SLE in 23 Centers - Data from the International Registry for Biologics In SLE (IRBIS)
R.F. van Vollenhoven1, Søren Jacobsen2, Daniel Wallace3, John G. Hanly4, Michelle Petri5, David A. Isenberg6, Sasha Bernatsky7, Sang-Cheol Bae8, Manuel Ramos-Casals9, Guillermo Ruiz-Irastorza10, Francisco J. García-Hernández11, Luis Saez12, José Luis Callejas13, Javier Rascón14, Enrique de Ramón15, Mª Mar Ayala-Gutiérrez15, Maite Camps15, Melinda Mild16, Murat Inanç17, Bahar Artim-Esen17, Rosalind Ramsey-Goldman18, Christine A. Peschken19, Danilo Squatrito20, László Kovács21, Andrea Doria22, Zoltan Szekanecz23, Elisa Gremese24 and Emilia I. Sato25, 1Karolinska University Hospital, Stockholm, Sweden, 2Copenhagen University Hospital, Copenhagen, Denmark, 3Cedars-Sinai/UCLA, Los Angeles, CA, 4Dalhousie University and Capital Health, Halifax, NS, 5Johns Hopkins Hospital, Baltimore, MD, 6University College London, London, United Kingdom, 7McGill UHC/RVH, Montreal, QC, 8Hanyang University Hospital for Rheumatic Diseases, Seoul, South Korea, 9Hospital Clínic, Barcelona, Spain, 10Hospital de Cruces, Bizkaia, Spain, 11Hospital Virgen del Rocío, Sevilla, Spain, 12Hospital Miguel Servet, Zaragoza, Spain, 13Hospital San Cecilio, Granada, Spain, 14Hospital Son Dureta, Palma de Mallorca, Spain, 15Hospital Carlos Haya, Málaga, Spain, 16Karolinska Institutet, Stockholm, Sweden, 17Istanbul University, Istanbul Medical Faculty, Istanbul, Turkey, 18Northwestern University Feinberg School of Medicine, Chicago, IL, 19Univ of Manitoba, Winnipeg, MB, 20Careggi Hospital- Florence, Florence, Italy, 21University of Szeged, Szeged, Hungary, 22University of Padova, Padova, Italy, 23University of Debrecen Medical and Health Sciences Center, Debrecen, Hungary, 24Rheumatology Unit, Catholic University, Roma, Italy, 25Escola Paulista de Medicina - Universidade Federal de São Paulo, Sao Paulo, Brazil
Hospital San Juan Bautista
Spanish LupusPRO: Cross Cultural Validation Study for Lupus
Meenakshi Jolly1, Joel A. Block1, Rachel A. Mikolaitis1, Daniel Wallace2, Sergio Duran-Barragán3, Ana M. Bertoli4, Sergio Toloza5, Ivana Blazevic6, Luis M. Vila7, Dilrukshie Cooray8, Emmanuel P. Katsaros9, Karina Marianne D. Torralba10, Michael H. Weisman11 and Graciela S. Alarcon12, 1Rush University Medical Center, Chicago, IL, 2Cedars-Sinai/UCLA, Los Angeles, CA, 3UIECD, Guadalajara, Mexico, Guadalajara, Mexico, 4Instituto Reumatológico Strusberg, Cordoba, Cordoba, Argentina, 5Hospital San Juan Bautista, Catamarca, Argentina, 6University of Buenos Aires, Buenos Aries, Argentina, 7University of PuertoRico Medical Sciences Campus, San Juan, PR, 8Harbor UCLA Medical Center, Torrance, CA, 9Loma Linda Univ, Loma Linda, CA, 10USC Keck Schl of Medicine, Los Angeles, CA, 11Cedars-Sinai Medical Center, Los Angeles, CA, 12University of Alabama at Birmingham, Birmingham, AL
Hospital San Martin
Work Disability Is Related to the Presence of Arthritis, Not to a Specific Diagnosis
Hernan Maldonado Ficco1, Rodolfo Perez Alamino1, Fernando Dal Pra1, Veronica Lencina1, Luciana Casalla2, Mariana Benegas2, Oscar Rillo3, Alberto Berman4, Ana Lucía Barbaglia4, Veronica Bellomio5, Francisco Caeiro6, Josefina Marcos7, Juan Carlos Marcos7, Antonio Catalan Pellet8, Rodrigo Garcia Salinas8, Sergio Paira9, Federico Ceccato9, Enrique Soriano10, Zaida Bendran10, Gabriela Salvatierra11 and Gustavo Citera1, 1Instituto de Rehabilitación Psicofísica, Buenos Aires, Argentina, 2Hospital Tornu, Buenos Aires, Argentina, 3Hospital Sirio Libanes, Buenos Aires, Argentina, 4Hospital Padilla, Tucuman, Argentina, 5Consultorio, Tucuman, Argentina, 6Hospital Privado de Cordoba, Cordoba, Argentina, 7Hospital San Martin, La Plata, Argentina, 8Hospital Rivadiavia, Buenos Aires, Argentina, 9Hospital Jose Maria Cullen, Santa Fe, Argentina, 10Hospital Italiano, Buenos Aires, Argentina, 11Centro de enfermedades Reumaticas, Santiago Del Estero, Argentina
Hospital Sant Joan de Déu
Adalimumab in 107 Refractory Uveitis: A Multicenter Study
Orlando Pompei1, Ricardo Blanco2, Manuel Diaz-llopis3, David Salom3, Carmen Garcia-Vicuña4, Miguel Cordero-Coma5, Gabriela Ortega-Larrocea6, Norberto Ortego-Centeno7, Marta Suarez-de-Figueroa8, J. Carlos Fernandez-Cid9, Alejandro Fonollosa10, Angel M. Garcia-Aparicio11, Jose M. Benítez-del-Castillo12, Jose L. Olea13 and J. Fernando Arevalo14, 1Hospital Universitario Marqués de Valdecilla. IFIMAV, Santander, Spain, 2Hospital Universitario Marqués de Valdecilla-IFIMAV, Santander, Spain, 3La Fe University Hospital of Valencia, Valencia, Spain, 4Hospital Sant Joan de Déu, Barcelona, Spain, 5Hospital de León, León, Spain, 6National Institute of Rehabilitation, D.F Mexico, Mexico, 7Hospital Clínico San Cecilio, Granada, Spain, 8Hospital Ramon y Cajal, Madrid, Spain, 9Hospital de Pontevedra, Pontevedra, Spain, 10Hospital de Cruces, Bilbao, Spain, 11Hospital Virgen de la Salud, Toledo, Spain, 12Hospital Clínico San Carlos, Madrid, 13Hospital Son Dureta, Palma de Mallorca, Spain, 14Ophthalmology Clinic Center of Caracas, Caracas, Venezuela
Hospital Selayang
Low Serum Levels of Soluble Receptor for Advanced Glycation End Products Are Associated with Increased Augmentation Index in Patients with Early Rheumatoid Arthritis
Lai Shan Tam1, Qing Shang1, Edmund K. Li1, Ka Lai Lee2, Ying Ying Leung3, King Yee Ying4, Cheuk-wan Yim5, Emily Kun6, Alexander M. Leung7, Martin Li1, Tena K. Li1, Tracy Y. Zhu1, Ricky K. Chui1, Lorraine Tseung1, Shui Lian Yu1, Woon Pang Kuan8 and Cheuk-Man Yu1, 1The Chinese University of Hong Kong, Hong Kong, Hong Kong, 2Pamela Youde Nethersole Eastern Hospital, Hong Kong, Hong Kong, 3North District Hospital, Hong Kong, Hong Kong, 4Princess Margaret Hospital, Hong Kong, Hong Kong, 5United Christian Hospital, Hong Kong, Hong Kong, 6Tai Po Hospital, Hong Kong, Hong Kong, 7Queen Elizabeth Hospital, Hong Kong, Hong Kong, 8Hospital Selayang, Kuala Lumpur, Malaysia

Infliximab Is Associated with Improvement in Arterial Stiffness in Patients with Early Rheumatoid Arthritis – a Randomized Trial
Lai Shan Tam1, Qing Shang1, Edmund K. Li1, Ka Lai Lee2, Ying Ying Leung3, King Yee Ying4, Cheuk-Wan Yim5, Emily W. Kun6, Alexander M. Leung7, Martin Li1, Tena K. Li1, Tracy Y. Zhu1, Ricky K. Chui1, Lorraine Tseung1, Shui Lian Yu1, Woon Pang Kuan8 and Cheuk-Man Yu1, 1The Chinese University of Hong Kong, Hong Kong, Hong Kong, 2Pamela Youde Nethersole Eastern Hospital, Hong Kong, Hong Kong, 3North District Hospital, Hong Kong, Hong Kong, 4Princess Margaret Hospital, Hong Kong, Hong Kong, 5United Christian Hospital, Hong Kong, Hong Kong, 6Tai Po Hospital, Hong Kong, Hong Kong, 7Queen Elizabeth Hospital, Hong Kong, Hong Kong, 8Hospital Selayang, Kuala Lumpur, Malaysia
Hospital Sierrallana
Circulating B Cells Subpopulations in Patients with Antiphospholip Syndrome
Lorena Alvarez-Rodriguez1, Marcos Lopez-Hoyos1, Jaime Calvo-Alen2, Rafael Barrio del1, Orlando Pompei1 and Victor M. Martinez-Taboada3, 1Hospital Universitario Marques de Valdecilla. IFIMAV, Santander, Spain, 2Hospital Sierrallana, Torrelavega, Spain, 3Hospital Universitario Marques de Valdecilla-IFIMAV, Santander, Spain

Circulating Cytokine Profile in Patients with Antiphospholipid Syndrome
Lorena Alvarez-Rodriguez1, Marcos Lopez-Hoyos1, Jaime Calvo-Alen2, Rafael Barrio del1, Orlando Pompei1 and Victor M. Martinez-Taboada3, 1Hospital Universitario Marques de Valdecilla. IFIMAV, Santander, Spain, 2Hospital Sierrallana, Torrelavega, Spain, 3Hospital Universitario Marques de Valdecilla-IFIMAV, Santander, Spain

Circulating cytokines in Patients with Hidradenitis Suppurativa: is there a Clue for new Therapeutic Options?
Orlando Pompei1, Lorena Álvarez-Rodríguez1, Ricardo Blanco1, Ignacio Villa2, Marcos López-Hoyos1, Marcos González López1, Hector Fernandez-Llaca1, M. del Carmen Gonzalez Vela1, Carmen Bejerano1, Inés Pérez-Martín1 and Victor M. Martinez-Taboada1, 1Hospital Universitario Marqués de Valdecilla-IFIMAV, Santander, Spain, 2Hospital Sierrallana, Torrelavega, Spain
Hospital Sirio Libanes
Work Disability Is Related to the Presence of Arthritis, Not to a Specific Diagnosis
Hernan Maldonado Ficco1, Rodolfo Perez Alamino1, Fernando Dal Pra1, Veronica Lencina1, Luciana Casalla2, Mariana Benegas2, Oscar Rillo3, Alberto Berman4, Ana Lucía Barbaglia4, Veronica Bellomio5, Francisco Caeiro6, Josefina Marcos7, Juan Carlos Marcos7, Antonio Catalan Pellet8, Rodrigo Garcia Salinas8, Sergio Paira9, Federico Ceccato9, Enrique Soriano10, Zaida Bendran10, Gabriela Salvatierra11 and Gustavo Citera1, 1Instituto de Rehabilitación Psicofísica, Buenos Aires, Argentina, 2Hospital Tornu, Buenos Aires, Argentina, 3Hospital Sirio Libanes, Buenos Aires, Argentina, 4Hospital Padilla, Tucuman, Argentina, 5Consultorio, Tucuman, Argentina, 6Hospital Privado de Cordoba, Cordoba, Argentina, 7Hospital San Martin, La Plata, Argentina, 8Hospital Rivadiavia, Buenos Aires, Argentina, 9Hospital Jose Maria Cullen, Santa Fe, Argentina, 10Hospital Italiano, Buenos Aires, Argentina, 11Centro de enfermedades Reumaticas, Santiago Del Estero, Argentina
Hospital Son Dureta
Biologics use in SLE in 23 Centers - Data from the International Registry for Biologics In SLE (IRBIS)
R.F. van Vollenhoven1, Søren Jacobsen2, Daniel Wallace3, John G. Hanly4, Michelle Petri5, David A. Isenberg6, Sasha Bernatsky7, Sang-Cheol Bae8, Manuel Ramos-Casals9, Guillermo Ruiz-Irastorza10, Francisco J. García-Hernández11, Luis Saez12, José Luis Callejas13, Javier Rascón14, Enrique de Ramón15, Mª Mar Ayala-Gutiérrez15, Maite Camps15, Melinda Mild16, Murat Inanç17, Bahar Artim-Esen17, Rosalind Ramsey-Goldman18, Christine A. Peschken19, Danilo Squatrito20, László Kovács21, Andrea Doria22, Zoltan Szekanecz23, Elisa Gremese24 and Emilia I. Sato25, 1Karolinska University Hospital, Stockholm, Sweden, 2Copenhagen University Hospital, Copenhagen, Denmark, 3Cedars-Sinai/UCLA, Los Angeles, CA, 4Dalhousie University and Capital Health, Halifax, NS, 5Johns Hopkins Hospital, Baltimore, MD, 6University College London, London, United Kingdom, 7McGill UHC/RVH, Montreal, QC, 8Hanyang University Hospital for Rheumatic Diseases, Seoul, South Korea, 9Hospital Clínic, Barcelona, Spain, 10Hospital de Cruces, Bizkaia, Spain, 11Hospital Virgen del Rocío, Sevilla, Spain, 12Hospital Miguel Servet, Zaragoza, Spain, 13Hospital San Cecilio, Granada, Spain, 14Hospital Son Dureta, Palma de Mallorca, Spain, 15Hospital Carlos Haya, Málaga, Spain, 16Karolinska Institutet, Stockholm, Sweden, 17Istanbul University, Istanbul Medical Faculty, Istanbul, Turkey, 18Northwestern University Feinberg School of Medicine, Chicago, IL, 19Univ of Manitoba, Winnipeg, MB, 20Careggi Hospital- Florence, Florence, Italy, 21University of Szeged, Szeged, Hungary, 22University of Padova, Padova, Italy, 23University of Debrecen Medical and Health Sciences Center, Debrecen, Hungary, 24Rheumatology Unit, Catholic University, Roma, Italy, 25Escola Paulista de Medicina - Universidade Federal de São Paulo, Sao Paulo, Brazil

Adalimumab in 107 Refractory Uveitis: A Multicenter Study
Orlando Pompei1, Ricardo Blanco2, Manuel Diaz-llopis3, David Salom3, Carmen Garcia-Vicuña4, Miguel Cordero-Coma5, Gabriela Ortega-Larrocea6, Norberto Ortego-Centeno7, Marta Suarez-de-Figueroa8, J. Carlos Fernandez-Cid9, Alejandro Fonollosa10, Angel M. Garcia-Aparicio11, Jose M. Benítez-del-Castillo12, Jose L. Olea13 and J. Fernando Arevalo14, 1Hospital Universitario Marqués de Valdecilla. IFIMAV, Santander, Spain, 2Hospital Universitario Marqués de Valdecilla-IFIMAV, Santander, Spain, 3La Fe University Hospital of Valencia, Valencia, Spain, 4Hospital Sant Joan de Déu, Barcelona, Spain, 5Hospital de León, León, Spain, 6National Institute of Rehabilitation, D.F Mexico, Mexico, 7Hospital Clínico San Cecilio, Granada, Spain, 8Hospital Ramon y Cajal, Madrid, Spain, 9Hospital de Pontevedra, Pontevedra, Spain, 10Hospital de Cruces, Bilbao, Spain, 11Hospital Virgen de la Salud, Toledo, Spain, 12Hospital Clínico San Carlos, Madrid, 13Hospital Son Dureta, Palma de Mallorca, Spain, 14Ophthalmology Clinic Center of Caracas, Caracas, Venezuela
Hospital Sonnenhof
Prevalence of Cam and Pincer-Type Deformities on Hip MRI in a Swiss Female Population: A Cross-Sectional Study
Stephan Reichenbach1, Peter Jüni1, Stefan Werlen2, Andreas Limacher1, Christian W. Pfirrmann3, Reinhold Ganz1 and Michael Leunig4, 1University of Bern, Bern, Switzerland, 2Hospital Sonnenhof, Bern, Switzerland, 3Balgrist University Hospital, Zurich, Switzerland, 4Schulthess Clinic, Zurich, Switzerland
Hospital Special Surgery
Knee Braces and Foot Orthosis for Knee Osteoarthritis
Howard J. Hillstrom, PhD; Rehabilitation, Hospital Special Surgery, New York, NY and Kelly D. Krohn, MD; DC 4109, Lilly USA, LLC, Indianapolis, IN
Hospital Special Surgery (HSS)
Factors Affecting Dynamic Foot Function in Older Adults: The Framingham Foot Study
Thomas J. Hagedorn1, Alyssa B. Dufour2, Yvonne M. Golightly3, Jody L. Riskowski4, Howard J. Hillstrom5, Virginia A. Casey1 and Marian T. Hannan6, 1Hebrew Senior Life, Boston, MA, 2Hebrew SeniorLife & Boston Univ, Boston, MA, 3University of North Carolina, Chapel Hill, NC, 4Hebrew SeniorLife, Boston, MA, 5Hospital Special Surgery (HSS), New York, NY, 6Hebrew SeniorLife & Harvard Med Sch, Boston, MA

The Relationship of Toe-Out Walking to Clinical Characteristics of 1st Metatarsophalangeal Joint Osteoarthritis in Older Adults: The MOST Study
K. Douglas Gross1, Howard J. Hillstrom2, Jingbo Niu3, Michael C. Nevitt4, Cora E. Lewis5, James Torner6 and David T. Felson3, 1MGH Institute of Health Professions, Boston, MA, 2Hospital Special Surgery (HSS), New York, NY, 3Boston University School of Medicine, Boston, MA, 4University of California-San Francisco, San Francisco, CA, 5University of Alabama, Birmingham City, Birmingham, AL, 6University of Iowa, Iowa City, Iowa City, IA

The Association of Vibratory Perception with Foot Plantar Pressures: The MOST Study
Najia Shakoor, Rush University Medical Center, Chicago, IL, Howard J. Hillstrom, Hospital Special Surgery (HSS), New York, NY, K. Douglas Gross, MGH Institute of Health Professions, Boston, MA, Ke Wang, Boston University, Boston, MA, David T. Felson, Boston University School of Medicine, Boston, MA, Neil Segal, University of Iowa, Iowa City, Cora E. Lewis, University of Alabama, Birmingham City, Birmingham, AL and Michael C. Nevitt, University of California-San Francisco, San Francisco, CA

Biomechanical Mechanisms Contributing to Foot Pain
Howard J. Hillstrom, Hospital Special Surgery (HSS), New York, NY
Hospital Sta Tecla
Changes in Psychological Status in Patients with Chronic Spondyloarthropathy Treated with Infliximab
Rosa M. Morlà1, Hector Corominas2, M. V. Hernandez3, Mireia Moreno4, Miquel Sala5, Vera Ortiz-Santamaria6, Patricia Reyner6, Vicente Torrente-Segarra Jr.7, Agusti Sellas Fernandez8, Georgina Salvador9, Elena Sirvent10, Cristina Masuet11 and Xavier Juanola-Roura12, 1Hospital Sta Tecla, Tarragona, Spain, 2Hospital Moises Broggi, Barcelona, 3Hospital Clinic of Barcelona, Barcelona, Spain, 4Servei de Reumatologia, Sabadell, Spain, 5Rheumatology Unit, Figueres, Spain, 6Unitat de Reumatologia, Spain, 7Hospital General de Hospitalet, Barcelona, Spain, 8Senior Consultant, Barcelon, Spain, 9Hospital Mutua de Terrassa. Barcelona, Barcelona, Spain, 10Hospital de Sant Boi, 11Hospital de Bellvitge, Hospitalet de LLobregat, Spain, 12Hospital Universitario de Bellvitge, Barcelona, Spain
Hospital Thurgau AG, Frauenfeld
Anterior Chest Wall Inflammation by Whole Body MRI in Patients with Spondyloarthritis: Lack of Association Between Clinical and Imaging Findings
Ulrich Weber1, Robert GW Lambert1, Kaspar Rufibach2, Walter P. Maksymowych1, Juerg Hodler3, Anna Zejden4, Stefan Duewell5, Rudolf O. Kissling6, Paul L. Filipow1 and Anne G. Jurik4, 1University of Alberta, Edmonton, AB, 2University of Zurich, Zurich, Switzerland, 3University Hospital Zurich, Zurich, Switzerland, 4University Hospital Aarhus, Aarhus, Denmark, 5Hospital Thurgau AG, Frauenfeld, Frauenfeld, Switzerland, 6Balgrist University Hospital, Zurich, Switzerland
Hospital Tornu
Work Disability Is Related to the Presence of Arthritis, Not to a Specific Diagnosis
Hernan Maldonado Ficco1, Rodolfo Perez Alamino1, Fernando Dal Pra1, Veronica Lencina1, Luciana Casalla2, Mariana Benegas2, Oscar Rillo3, Alberto Berman4, Ana Lucía Barbaglia4, Veronica Bellomio5, Francisco Caeiro6, Josefina Marcos7, Juan Carlos Marcos7, Antonio Catalan Pellet8, Rodrigo Garcia Salinas8, Sergio Paira9, Federico Ceccato9, Enrique Soriano10, Zaida Bendran10, Gabriela Salvatierra11 and Gustavo Citera1, 1Instituto de Rehabilitación Psicofísica, Buenos Aires, Argentina, 2Hospital Tornu, Buenos Aires, Argentina, 3Hospital Sirio Libanes, Buenos Aires, Argentina, 4Hospital Padilla, Tucuman, Argentina, 5Consultorio, Tucuman, Argentina, 6Hospital Privado de Cordoba, Cordoba, Argentina, 7Hospital San Martin, La Plata, Argentina, 8Hospital Rivadiavia, Buenos Aires, Argentina, 9Hospital Jose Maria Cullen, Santa Fe, Argentina, 10Hospital Italiano, Buenos Aires, Argentina, 11Centro de enfermedades Reumaticas, Santiago Del Estero, Argentina
Hospital Universitari General Vall d'Hebron
Genome-Wide Association Study of Dermatomyositis Reveals Shared Genetic Risk Factors with Other Autoimmune Diseases
Frederick W. Miller1, Robert G. Cooper2, Jiri Vencovsky3, Lisa G. Rider4, Katalin Danko5, Lucy R. Wedderburn6, Ingrid E. Lundberg7, Lauren M. Pachman8, Ann M. Reed9, Steven R. Ytterberg9, Leonid Padyukov10, Albert Selva O'Callaghan11, Timothy Radstake12, David A. Isenberg13, Hector Chinoy14, William E. Ollier15, Terrance O'Hanlon16, Bo Peng17, Paul Scheet17, Annette T. Lee18, Janine Lamb14, Wei Chen17, Christopher Amos17, Peter K. Gregersen19 and Myositis Genetics Consortium20, 1NIH/NIEHS NIH Bldg 10 4-2330, Bethesda, MD, 2Hope Hospital, Salford, United Kingdom, 3Institute of Rheumatology, Prague 2, Czech Republic, 4NIEHS NIH, Bethesda, MD, 5University of Debrecen, Debrecen, Hungary, Debrecan, Hungary, 6University College London (UCL), London, United Kingdom, 7Karolinska Institutet, Stockholm, Sweden, 8Northwestern University Feinberg School of Medicine, Chicago, IL, 9Mayo Clinic, Rochester, MN, 10Rheumatology Unit, Karolinska Institutet, Stockholm, Sweden, 11Hospital Universitari General Vall d'Hebron, Barcelona, Spain, 12Geert Groote Plein 8, Nymegen, Netherlands, 13University College London, London, United Kingdom, 14Manchester, United Kingdom, 15Univ of Manchester Med School, Manchester, United Kingdom, 16NIH, Bethesda, MD, 17Houston, TX, 18Feinstein Institute Med Rsch, Manhasset, NY, 19Feinstein Institute Medical Reschearch, Manhasset, NY, 20Bethesda
Hospital Universitario 12 de Octubre
Validation of Potential Classification Criteria for Systemic Sclerosis
Sindhu R. Johnson, Toronto Western and Mt. Sinai Hospitals, University of Toronto, Toronto, ON, Jaap Fransen, The Radboud University Nijmegen Medical Centre, Nijmegen, Netherlands, Dinesh Khanna, University of Michigan, Ann Arbor, MI, Thomas A. Medsger, Univ of Pittsburgh, Pittsburgh, PA, Christine A. Peschken, University of Manitoba, Winnipeg, MB, Patricia Carreira, Hospital Universitario 12 de Octubre, Madrid, Spain, Gabriela Riemekasten, Charité University Hospital, German Rheumatology Research Center, a Leibniz Institute, Berlin, Germany, Alan G. Tyndall, University of Basel, Basel, Switzerland, Marco Matucci-Cerinic, Univ Florence, Firenze, Italy, Murray Baron, Jewish General Hospital, Montreal, QC, Frank Van den Hoogen, Nijmegen, Netherlands and Janet E. Pope, St. Joseph's Health Care, University of Western Ontario, London, ON
HOSPITAL UNIVERSITARIO 12 DE OCTUBRE
CLINICAL Associations of Elevated ACUTE PHASE RESPONSE, Proteinuria and LOW Dlco In EARLY SCLERODERMA PATIENTS: A REPORT FROM the EULAR SCLERODERMA TRIALS and RESEARCH GROUP (EUSTAR) Database
Patricia E. Carreira, Instituto de Investigación Hospital 12 de Octubre (I+12), Madrid, Spain, Loreto Carmona, Fundación Española de Reumatología, Madrid, Spain, Beatriz E. Joven, HOSPITAL UNIVERSITARIO 12 DE OCTUBRE, MADRID, Spain, Christopher D. Denton, Royal Free Hospital, Medical School, London, England, Yannick Allanore, Paris Descartes University, Rheumatology A department, Cochin Hospital, Paris, France, Ulrich A. Walker, Dept. of Rheumatology at Basel University, Felix-Platter Spital, Basel, Switzerland, Marco Matucci-Cerinic, Univ Florence, Firenze, Italy, Ulf Muller-Ladner, Justus-Liebig Universität Gießen, Kerckhoff-Klinik GmbH, Bad Nauheim, Germany and EUSTAR coauthors, Florence
Hospital universitario Belvitge,
Correlation Biomarkers of Cartilage and BONE Turnover with DISEASE ACTIVITY, Function, QUALITY of LIFE, Radiology and MAGNETIC RESONANCE  Imaging  IN PATIENTS with EARLY Spondiloarthritis
Raquel Almodovar1, Valeria Ríos2, Sara Ocaña1, Milena Gobbo3, Marisa Casas1, Pedro Zarco4 and Xavier Juanola-Roura5, 1Hospital Universitario Fundación Alcorcón, Alcorcon. Madrid, Spain, 2Hospital universitario Belvitge,, Barcelona, Spain, 3Spanish Society of Rheumatology, Madrid, Spain, 4Fundación Hopsital Alcorcon, Alcorcon, Madrid, Spain, 5Hospital Universitario de Bellvitge, Barcelona, Spain
Hospital Universitario de Bellvitge
Correlation Biomarkers of Cartilage and BONE Turnover with DISEASE ACTIVITY, Function, QUALITY of LIFE, Radiology and MAGNETIC RESONANCE  Imaging  IN PATIENTS with EARLY Spondiloarthritis
Raquel Almodovar1, Valeria Ríos2, Sara Ocaña1, Milena Gobbo3, Marisa Casas1, Pedro Zarco4 and Xavier Juanola-Roura5, 1Hospital Universitario Fundación Alcorcón, Alcorcon. Madrid, Spain, 2Hospital universitario Belvitge,, Barcelona, Spain, 3Spanish Society of Rheumatology, Madrid, Spain, 4Fundación Hopsital Alcorcon, Alcorcon, Madrid, Spain, 5Hospital Universitario de Bellvitge, Barcelona, Spain

Changes in Psychological Status in Patients with Chronic Spondyloarthropathy Treated with Infliximab
Rosa M. Morlà1, Hector Corominas2, M. V. Hernandez3, Mireia Moreno4, Miquel Sala5, Vera Ortiz-Santamaria6, Patricia Reyner6, Vicente Torrente-Segarra Jr.7, Agusti Sellas Fernandez8, Georgina Salvador9, Elena Sirvent10, Cristina Masuet11 and Xavier Juanola-Roura12, 1Hospital Sta Tecla, Tarragona, Spain, 2Hospital Moises Broggi, Barcelona, 3Hospital Clinic of Barcelona, Barcelona, Spain, 4Servei de Reumatologia, Sabadell, Spain, 5Rheumatology Unit, Figueres, Spain, 6Unitat de Reumatologia, Spain, 7Hospital General de Hospitalet, Barcelona, Spain, 8Senior Consultant, Barcelon, Spain, 9Hospital Mutua de Terrassa. Barcelona, Barcelona, Spain, 10Hospital de Sant Boi, 11Hospital de Bellvitge, Hospitalet de LLobregat, Spain, 12Hospital Universitario de Bellvitge, Barcelona, Spain

DEVELOPMENT of Ischemic COMPLICATIONS In PATIENTS with Giant CELL Arteritis Presenting with Apparently Isolated Polymyalgia Rheumatica
Paula Estrada, Javier Narvaez, Laura Lopez-Vives, Irene Martín-Esteve, Carmen Gomez-Vaquero and Joan Miquel Nolla, Hospital Universitario de Bellvitge, Barcelona, Spain
Hospital Universitario de Canarias
Superoxide Anion Mediates the L-Selectin Down-Regulation Induced by Non-Steroidal Anti-Inflammatory Drugs In Human Neutrophils
M. Jesus Dominguez-Luis1, Ada Herrera-Garcia2, M.Teresa Arce-Franco3, Susana Cardenas4, Marta Rodriguez-Pardo5, Manuel Feria5, Francisco Sanchez-Madrid4 and Federico Diaz-Gonzalez3, 1Hospital Universitario de Canarias, La Laguna, Spain, 2Hospital Universitario de Canarias, La Laguna. Tenerife, Spain, 3Rheumatology Service, La Laguna, Spain, 4Hospital Universitario La Princesa, Madrid, Spain, 5University of La Laguna, La Laguna. Tenerife, Spain

Inflammation-Dependent Insulin Resistance Is Present in Rheumatoid Arthritis but it Is Not Associated with Retinol Binding Protein 4
Vanesa Hernandez-Hernandez1, Esmeralda Delgado-Frías1, Ivan Ferraz-Amaro1, Jose A. Garcia-Dopico2, Lilian Medina2, Antonieta Gonzalez-Diaz3, Maria A. Gomez- Rodriguez-Bethencourt3, Jose Ramon Muñiz4, Ana I. Rodriguez-Vargas1, M. Angeles Gantes-Mora1, M.Teresa Arce-Franco1, M. Jesus Dominguez-Luis5 and Federico Diaz-Gonzalez1, 1Rheumatology Service, La Laguna, Spain, 2Laboratorio Central, La Laguna, Spain, 3Medicina Nuclear, Spain, 4Resonancia Magnetica IMETISA, 5Hospital Universitario de Canarias, La Laguna, Spain

Role of Liver X Receptors In the Regulation of Effector Functions of Fibroblast-Like Synoviocytes In Rheumatoid Arthritis
M.Teresa Arce-Franco1, M. Jesus Dominguez-Luis2, Ana Diaz-Martin2, Ada Herrera-Garcia3, Maria Eugenia Miranda-Carus4, Sagrario Bustabad-Reyes3, Antonio Castrillo5 and Federico Diaz-Gonzalez1, 1Rheumatology Service, La Laguna, Spain, 2Hospital Universitario de Canarias, La Laguna, Spain, 3Hospital Universitario de Canarias, La Laguna. Tenerife, Spain, 4La Paz Hospital. IdiPaz, Madrid, Spain, 5University of Las Palmas de Gran Canaria (ULPGC), Canary Islands, Las Palmas (Gran Canaria), Spain

Assesment of Physical Activity by Accelerometry: Relationship Between Physical Function and Disease Activity in Rheumatoid Arthritis Patients
Vanesa Hernandez-Hernandez1, Esmeralda Delgado-Frías1, Ivan Ferraz-Amaro1, Jose A. Garcia-Dopico2, Lilian Medina2, Inmaculada Alonso1, M.Teresa Arce-Franco1, M. Jesus Dominguez-Luis3 and Federico Diaz-Gonzalez1, 1Rheumatology Service, La Laguna, Spain, 2Central Laboratory, La Laguna, Spain, 3Hospital Universitario de Canarias, La Laguna, Spain
Hospital Universitario de Caracas
Linker for Activation of T Cells Is Displaced From the Immunological Synapse in Lupus T Cells After T Cell Activation
Nursamaa Abdoel1, Carmen Bracho2, Martin A. Rodriguez1 and Ana M. Blasini1, 1Hospital Universitario de Caracas, Caracas, Venezuela, 2Instituto Venezolano de Investigaciones Científicas, Miranda, Venezuela
Hospital Universitario de la Princesa, IIS Princesa,
Rheumatoid Arthritis: Patient Insights, Strategies and Expectations— Dual Survey Offers Physicians Unique Insight Into Patient Experience
Gerd R. Burmester, Charité - Universitätsmedizin Berlin, Berlin, Germany, Theresa Lupton, Univ of Calgary Medical Clinics, Calgary, AB, JM Alvaro-Gracia, Hospital Universitario de la Princesa, IIS Princesa,, Madrid, Spain and Boulos Haraoui, Institut de Rhumatologie, Montreal, QC
Hospital Universitario de La Princesa. IIS Princesa
Regulation of Suppressor of Cytokine Signaling-1, -2 and -3 Expression in Patients with Early Arthritis
Ricardo J. Villares1, Amalia Lamana2, Coloma Costas1, Ana M. Ortiz2, Mercedes López-Santalla1, Mario Mellado1 and Isidoro González-Alvaro2, 1Centro Nacional de Biotecnología. CNIC, Madrid, Spain, 2Hospital Universitario de La Princesa. IIS Princesa, Madrid, Spain

Comparison of the 1987 and 2010 Classificatioh Criteria for Rheumatoid Arthritis in a Population of Patients with Early Arthritis
Ana M. Ortiz Garcia, Ana M. Fernández-Ortiz, Silvia Pérez-Esteban, Rosario Garcia-Vicuña and Isidoro González-Alvaro, Hospital Universitario de La Princesa. IIS Princesa, Madrid, Spain

Development and Validation of a New Disease Activity Index As a Numerical Sum of 4 Variables, Including Erythrocyte Sedimentation Rate and/or C-Reactive Protein, to Assess Rheumatoid Arthritis
Isabel Castrejón1, Loreto Carmona2, Ana M. Ortiz3, Miguel A. Belmonte Serrano4, Juan A. martínez-López5 and Isidoro González-Alvaro3, 1NYU Hospital for Joint Diseases, New York, NY, 2Universidad Camilo José Cela, Villanueva de la Cañada, Spain, 3Hospital Universitario de La Princesa. IIS Princesa, Madrid, Spain, 4Hospital General de Castellon, Castellon, Spain, 5Fundación Jimenez Díaz, Madrid, Spain

Effect of Disease Activity on Lipoproteins Levels in Patients with Early Arthritis
Silvia Pérez-Esteban, Ana M. Ortiz, Ana M. Fernández-Ortiz, Santos Castañeda and Isidoro González-Alvaro, Hospital Universitario de La Princesa. IIS Princesa, Madrid, Spain

The STAT4 rs7574865 Polymorphism Is Associated with Differences in Disease Activity and Disability in Patients Wirh Early Arthritis
Ana M. Ortiz1, Amalia Lamana1, Alejandro Balsa2, Blanca Rueda3, Laura Nuño2, Maria Eugenia Miranda-Carus2, María F. González-Escribano4, Miguel A. López-Nebot5, Dora Pascual-Salcedo2, Javier Martin6 and Isidoro González-Alvaro1, 1Hospital Universitario de La Princesa. IIS Princesa, Madrid, Spain, 2Hospital La Paz. IdiPaz, Madrid, Spain, 3Facultad de Ciencias de la Salud. Universidad de Granada, Granada, Spain, 4Hospital Universitario Virgen del Rocío, Sevilla, Spain, 5Hospital Universitario Virgen de las Nieves, Granada, Spain, 6Instituto de Parasitologia y Biomedicina Lopez-Neyra (CSIC), Granada, Spain
Hospital Universitario Dr Negrín
The Lupus Damage Index Questionnaire and Its Correlation with the SLICC/ACR Damage Index and the LupusQoL in a Spanish Multicenter Lupus Cohort. Is It Really Measuring Damage?
José M. Pego-Reigosa1, Íñigo Rúa-Figueroa2, Teresa Otón-Sánchez1, Manuela Fontanillo-Fontanillo1, María Galindo-Izquierdo3, Esther Uriarte-Isacelaya4, Bruno Aspe-de la Iglesia5, Laura Cáceres-Martín2 and Félix Francisco-Hernández2, 1Hospital do Meixoeiro, Vigo, Spain, 2Hospital Universitario Dr Negrín, Las Palmas de Gran Canaria, Spain, 3Hospital 12 de octubre, Madrid, Spain, 4Donosti, Spain, 5Vigo, Spain
Hospital Universitario Dr Peset
Are Training Sessions Useful for Ultrasound Scan Evaluation of Synovitis In Rheumatoid Arthritis?
Andrés Ponce, Hospital General de Granollers, Granollers, Spain, Juan J. Alegre, Hospital Universitario Dr Peset, Valencia, Spain, Manuel Castaño, Hospital Universitario Virgen de la Arrixaca, Murcia, Spain, Ricardo Gutierrez-Polo, C.H. de Navarra, Pamplona, Spain, Francisco G. Jiménez-Núñez, Hospital Regional Universitario Carlos Haya., Malaga, Spain, María P. Macarrón, Hospital Clínico San Carlos, Madrid, Spain and Jesús Garrido, Facultad de Psicología.Universidad Autónoma de Madrid, Madrid, Spain
Hospital Universitario Fundación Alcorcón
Correlation Biomarkers of Cartilage and BONE Turnover with DISEASE ACTIVITY, Function, QUALITY of LIFE, Radiology and MAGNETIC RESONANCE  Imaging  IN PATIENTS with EARLY Spondiloarthritis
Raquel Almodovar1, Valeria Ríos2, Sara Ocaña1, Milena Gobbo3, Marisa Casas1, Pedro Zarco4 and Xavier Juanola-Roura5, 1Hospital Universitario Fundación Alcorcón, Alcorcon. Madrid, Spain, 2Hospital universitario Belvitge,, Barcelona, Spain, 3Spanish Society of Rheumatology, Madrid, Spain, 4Fundación Hopsital Alcorcon, Alcorcon, Madrid, Spain, 5Hospital Universitario de Bellvitge, Barcelona, Spain
Hospital Universitario Germans Trias i Pujol
Interferon-γ Release Assays In Rheumatic Patients: Baseline Study and In the Course of Anti-Tumor Necrosis Factor-α Agents
Melania Martínez-Morillo1, Sonia Mínguez2, Lourdes Mateo-Soria1, Irene Latorre1, José Domínguez1, Dolors Grados1, Beatriz Tejera1, Susana Holgado1, Alejandro Olivé1 and Xavier Tena1, 1Hospital Universitario Germans Trias i Pujol, Badalona, Spain, 2Hospital General de Manresa, Manresa, Spain
Hospital Universitario La Fe
Extended Safety Observations From Denosumab Administration in Postmenopausal Women From the FREEDOM and FREEDOM Extension Trials
J. P. Brown1, H. G. Bone2, R. Chapurlat3, C. Libanati4, M. L. Brandi5, E. Czerwinski6, M.-A. Krieg7, Z. Man8, D. Mellström9, S. C. Radominski10, J.-Y. Reginster11, H. Resch12, J. A. Román Ivorra13, C. Roux14, N. S. Daizadeh4, A. Grauer4, S. R. Cummings15 and S. Papapoulos16, 1CHUQ-CHUL Research Centre, Laval University, Quebec City, QC, 2Michigan Bone & Mineral Clinic, Detroit, MI, 3Hôpital Edouard Herriot, Lyon, France, 4Amgen Inc., Thousand Oaks, CA, 5University of Florence, Florence, Italy, 6Krakow Medical Center, Krakow, Poland, 7University Hospital of Lausanne, Lausanne, Switzerland, 8Centro TIEMPO, Buenos Aires, Argentina, 9Sahlgrenska University Hospital, Göteborg, Sweden, 10Universidade Federal do Paraná, Curitiba, Brazil, 11University of Liège, Liège, Belgium, 12St. Vincent Hospital, Vienna, Austria, 13Hospital Universitario La Fe, Valencia, Spain, 14Paris Descartes University, Paris, France, 15San Francisco Coordinating Center, CPMC Research Institute, San Francisco, CA, 16Leiden University Medical Center, Leiden, Netherlands

Comparison of Tocilizumab As Monotherapy or with Add-on Disease-Modifying Antirheumatic Drugs in Patients with Rheumatoid Arthritis and An Inadequate Response to Previous Treatments
Vivian Bykerk1, Andrew Östör2, José Andrés Román Ivorra3, Jürgen Wollenhaupt4, Andrea Stancati5, Corrado Bernasconi5 and Jean Sibilia6, 1Brigham & Women's Hospital, Boston, MA, 2University of Cambridge, Cambridge, United Kingdom, 3Hospital Universitario La Fe, Valencia, Spain, 4Schön Klinik, Hamburg, Germany, 5Roche, Basel, Switzerland, 6CHU Hautepierre, Strasbourg, France

Six Years of Denosumab Treatment in Postmenopausal Women with Osteoporosis:  Results From the First Three Years of the FREEDOM Extension
J.P. Brown1, H. G. Bone2, R. Chapurlat3, N. Franchimont4, M. L. Brandi5, E. Czerwinski6, M.-A. Krieg7, Z. Man8, D. Mellström9, S. C. Radominski10, J.-Y. Reginster11, H. Resch12, J. A. Román Ivorra13, C. Roux14, N. S. Daizadeh4, M. L. Geller4, S. Smith4, R.B. Wagman4, S. R. Cummings15 and S. Papapoulos16, 1CHUQ-CHUL Research Centre, Laval University, Quebec City, QC, 2Michigan Bone & Mineral Clinic, Detroit, MI, 3Hôpital Edouard Herriot, Lyon, France, 4Amgen Inc., Thousand Oaks, CA, 5University of Florence, Florence, Italy, 6Krakow Medical Center, Krakow, Poland, 7University Hospital of Lausanne, Lausanne, Switzerland, 8Centro TIEMPO, Buenos Aires, Argentina, 9Sahlgrenska University Hospital, Göteborg, Sweden, 10Universidade Federal do Paraná, Curitiba, Brazil, 11University of Liège, Liège, Belgium, 12St. Vincent Hospital, Vienna, Austria, 13Hospital Universitario La Fe, Valencia, Spain, 14Paris Descartes University, Paris, France, 15San Francisco Coordinating Center, CPMC Research Institute, and UCSF, San Francisco, CA, 16Leiden University Medical Center, Leiden, Netherlands
Hospital Universitario La Paz
A Comparison of Optical Coherence Tomography and Clinical Assessment of Nail Disease in Psoriasis and Psoriatic Arthritis
Concepcion Castillo-Gallego1, Sibel Aydin2, Zoe R. Ash3, Giusepinna Abignano3, Paul Emery4, Helena Marzo-Ortega3, Francesco Del Galdo3 and Dennis McGonagle3, 1Hospital Universitario La Paz, Madrid, Spain, 2Goztepe Training and Research Hospital, Istanbul, Turkey, 3University of Leeds, Leeds, United Kingdom, 4Chapel Allerton Hospital, Leeds, United Kingdom

Optical Coherence Tomography: A New Imaging Technique That Allows Detailed Visualization of Affected Scleroderma Skin
Giuseppina Abignano1, Sibel Aydin2, Concepcion Castillo-Gallego Jr.3, Maya H. Buch1, Paul Emery4 and Francesco Del Galdo1, 1University of Leeds, Leeds, United Kingdom, 2Goztepe Training and Research Hospital, Istanbul, Turkey, 3Hospital Universitario La Paz, Madrid, Spain, 4Chapel Allerton Hospital, Leeds, United Kingdom

Nail Disease in Psoriasis Is Associated with Sonographically Determined Systemic Subclinical Enthesopathy
Zoe R. Ash1, Ilaria Tinazzi2, Concepcion Castillo-Gallego3, Chung Kwok4, Caroline Wilson5, Mark Goodfield5, Paolo Gisondi6, Ai Lyn Tan1, Helena Marzo-Ortega1, Richard J. Wakefield7, Paul Emery8, Sibel Aydin9 and Dennis McGonagle10, 1University of Leeds, Leeds, United Kingdom, 2University of Verona, Verona, Italy, 3Hospital Universitario La Paz, Madrid, Spain, 4Leeds Teaching Hospitals, Leeds, United Kingdom, 5Leeds Teaching Hospitals NHS Trust, Leeds, United Kingdom, 6University of Veronia, Verona, Italy, 7Leeds Institute of Molecular Medicine, University of Leeds and NIHR Leeds Musculoskeletal Biomedical Research Unit, Leeds Teaching Hospitals, Leeds, United Kingdom, 8Chapel Allerton Hospital, Leeds, United Kingdom, 9Goztepe Training and Research Hospital, Istanbul, Turkey, 10University of Leeds and Leeds Teaching Hospitals, Leeds, United Kingdom

Tofacitinib (CP-690,550) in Combination with Traditional Disease-Modifying Anti-Rheumatic Drugs: Phase 3 Study Patient-Reported Outcomes in Patients with Active Rheumatoid Arthritis and An Inadequate Response to Disease-Modifying Anti-Rheumatic Drugs
V. Strand1, J. M. Kremer2, Z. G. Li3, S. Hall4, Roy M. Fleischmann5, M. C. Genovese6, E. Martin-Mola7, J. Isaacs8, D. Gruben9, G. Wallenstein9, S. Krishnaswami9, S. H. Zwillich9, T. Koncz10, R. Riese9, J. D. Bradley9 and the ORAL Sync investigators11, 1Stanford University, Palo Alto, CA, 2Albany Medical College and The Center for Rheumatology, Albany, NY, 3Peking University People's Hospital, Peking, China, 4Melbourne Rheumatology, Melbourne, Australia, 5MCRC, University of Texas, Dallas, TX, 6Stanford University Medical Center, Palo Alto, CA, 7Hospital Universitario La Paz, Madrid, Spain, 8University of Newcastle upon Tyne, Newcastle upon Tyne, United Kingdom, 9Pfizer Inc., Groton, CT, 10Pfizer Inc., New York, NY, 11Groton

Double-Blind Study of Tocilizumab Plus Methotrexate Vs Tocilizumab Plus Placebo in Patients with Active Rheumatoid Arthritis Despite Prior Methotrexate: Progression of Structural Damage, Quality of Life, and Physical Function At 24 Weeks
Maxime Dougados, Paris-Descartes University, Cochin Hospital, Paris, France, Karsten Kissel, F. Hoffmann-La Roche Ltd, Basel, Switzerland, Howard Amital, Sheba Medical Center, Tel-hashomer, Israel, Philip G. Conaghan, NIHR-Leeds Biomedical Research Unit and Leeds Institute of Molecular Medicine, University of Leeds, Leeds, United Kingdom, Emilio Martin-Mola, Hospital Universitario La Paz, Madrid, Spain, Evgeny L. Nasonov, Institute of Rheumatology, Moscow, Russia, Georg Schett, Department of Internal Medicine 3 and Institute for Clinical Immunology, University of Erlangen-Nuremberg, Erlangen, Germany, Orrin M. Troum, USC Keck School of Medicine, Santa Monica, CA, Tiina Veldi, East-Tallinn Central Hospital, Tallinn, Estonia, Corrado Bernasconi, Roche, Basel, Switzerland and T.W.J. Huizinga, Leiden University Medical Center, Leiden, Netherlands
Hospital Universitario La Princesa
Superoxide Anion Mediates the L-Selectin Down-Regulation Induced by Non-Steroidal Anti-Inflammatory Drugs In Human Neutrophils
M. Jesus Dominguez-Luis1, Ada Herrera-Garcia2, M.Teresa Arce-Franco3, Susana Cardenas4, Marta Rodriguez-Pardo5, Manuel Feria5, Francisco Sanchez-Madrid4 and Federico Diaz-Gonzalez3, 1Hospital Universitario de Canarias, La Laguna, Spain, 2Hospital Universitario de Canarias, La Laguna. Tenerife, Spain, 3Rheumatology Service, La Laguna, Spain, 4Hospital Universitario La Princesa, Madrid, Spain, 5University of La Laguna, La Laguna. Tenerife, Spain
Hospital Universitario Madrid Norte Sanchinarro
The IRF7 Region Is Associated with Anti-Centromere Autoantibody Production in Systemic Sclerosis Patients
F. David Carmona1, Ramana Gutala2, Carmen P. Simeón3, Patricia E. Carreira4, Norberto Ortego-Centeno5, Esther Vicente-Rabaneda6, Francisco J. García-Hernández7, Paloma García de la Peña8, Mónica Fernández-Castro9, Lina Martínez-Estupiñán10, María-Victoria Egurbide11, Spanish Scleroderma Group, Betty P. Tsao13, Pravitt R. Gourh14, Sandeep K. Agarwal15, Shervin Assassi16, Maureen D. Mayes15, Frank C. Arnett15, Filemon K. Tan15 and Javier Martín17, 1Consejo Superior de Investigaciones Científicas, Armilla (Granada), Spain, 2The University of Texas Health Science Center, Houston, TX, 3Hospital Valle de Hebron, Barcelona, Spain, 4Instituto de Investigación Hospital 12 de Octubre (I+12), Madrid, Spain, 5Hospital Clínico San Cecilio, Granada, Spain, 6Hospital de la Princesa, Madrid, Spain, 7Hospital Virgen del Rocío, Sevilla, Spain, 8Hospital Universitario Madrid Norte Sanchinarro, Madrid, Spain, 9Hospital Puerta de Hierro, Madrid, Spain, 10Gregorio Marañón Hospital, Madrid, Spain, 11Hospital de Cruces, UPV/EHU, Barakaldo, Spain, Barakaldo, Spain, 12David Geffen School of Medicine University of California Los Angeles, Los Angeles, CA, 13UTHSC-Houston Medical School, Houston, TX, 14University of Texas Health Science Center at Houston, Houston, TX, 15Univ of Texas Health Science, Houston, TX, 16Consejo Superior de Investigaciones Científicas, Granada, Spain
Hospital Universitario Marques De Valdecilla
Tofacitinib (CP-690,550), An Oral Janus Kinase Inhibitor, in Combination with Methotrexate, in Patients with Active Rheumatoid Arthritis with An Inadequate Response to Tumor Necrosis Factor-Inhibitors: A 6-Month Phase 3 Study
Gerd-Rüdiger Burmester1, R. Blanco2, C. Charles-Schoeman3, J. Wollenhaupt4, C A. F. Zerbini5, B. Benda6, D. Gruben7, G. Wallenstein7, S. Krishnaswami7, S. H. Zwillich7, T. Koncz8, J. D. Bradley7, C. A. Mebus7 and the ORAL Step investigators9, 1Charité - University Medicine Berlin, Berlin, Germany, 2Hospital Universitario Marques De Valdecilla, Santander, Spain, 3University of California, Los Angeles, CA, 4Schön Klinik, Hamburg, Germany, 5Centro Paulista de Investigação Clinica, Sao Paulo, Brazil, 6Pfizer Inc., Collegeville, PA, 7Pfizer Inc., Groton, CT, 8Pfizer Inc., New York, NY, 9Groton
Hospital Universitario Marques de Valdecilla-IFIMAV
Circulating B Cells Subpopulations in Patients with Antiphospholip Syndrome
Lorena Alvarez-Rodriguez1, Marcos Lopez-Hoyos1, Jaime Calvo-Alen2, Rafael Barrio del1, Orlando Pompei1 and Victor M. Martinez-Taboada3, 1Hospital Universitario Marques de Valdecilla. IFIMAV, Santander, Spain, 2Hospital Sierrallana, Torrelavega, Spain, 3Hospital Universitario Marques de Valdecilla-IFIMAV, Santander, Spain

Circulating Cytokine Profile in Patients with Antiphospholipid Syndrome
Lorena Alvarez-Rodriguez1, Marcos Lopez-Hoyos1, Jaime Calvo-Alen2, Rafael Barrio del1, Orlando Pompei1 and Victor M. Martinez-Taboada3, 1Hospital Universitario Marques de Valdecilla. IFIMAV, Santander, Spain, 2Hospital Sierrallana, Torrelavega, Spain, 3Hospital Universitario Marques de Valdecilla-IFIMAV, Santander, Spain
Hospital Universitario Marqués de Valdecilla-IFIMAV
Circulating cytokines in Patients with Hidradenitis Suppurativa: is there a Clue for new Therapeutic Options?
Orlando Pompei1, Lorena Álvarez-Rodríguez1, Ricardo Blanco1, Ignacio Villa2, Marcos López-Hoyos1, Marcos González López1, Hector Fernandez-Llaca1, M. del Carmen Gonzalez Vela1, Carmen Bejerano1, Inés Pérez-Martín1 and Victor M. Martinez-Taboada1, 1Hospital Universitario Marqués de Valdecilla-IFIMAV, Santander, Spain, 2Hospital Sierrallana, Torrelavega, Spain

High Dose Intravenous Methylprednisolone Induces Rapid Improvement In Severe Uveitis: A Multicenter Study
Carmen Bejerano1, Ricardo Blanco1, Emma Beltrán2, Alejandro Fonollosa3, Olga Maiz4, Ana Blanco-Esteban4, Miguel Cordero5, Inés Pérez-Martín6, Joaquín Cañal6, Juan Ventosa6 and Miguel Angel González-Gay6, 1Hospital Universitario Marqués de Valdecilla-IFIMAV, Santander, Spain, 2Hospital Peset, Valencia, Spain, 3Hospital de Cruces, Barakaldo-Bilbao, Spain, 4Hospital Donostia, San Sebastian, Spain, 5Hospital León, León, Spain, 6Hospital Universitario Marqués de Valdecilla. IFIMAV, Santander, Spain

Adalimumab in 107 Refractory Uveitis: A Multicenter Study
Orlando Pompei1, Ricardo Blanco2, Manuel Diaz-llopis3, David Salom3, Carmen Garcia-Vicuña4, Miguel Cordero-Coma5, Gabriela Ortega-Larrocea6, Norberto Ortego-Centeno7, Marta Suarez-de-Figueroa8, J. Carlos Fernandez-Cid9, Alejandro Fonollosa10, Angel M. Garcia-Aparicio11, Jose M. Benítez-del-Castillo12, Jose L. Olea13 and J. Fernando Arevalo14, 1Hospital Universitario Marqués de Valdecilla. IFIMAV, Santander, Spain, 2Hospital Universitario Marqués de Valdecilla-IFIMAV, Santander, Spain, 3La Fe University Hospital of Valencia, Valencia, Spain, 4Hospital Sant Joan de Déu, Barcelona, Spain, 5Hospital de León, León, Spain, 6National Institute of Rehabilitation, D.F Mexico, Mexico, 7Hospital Clínico San Cecilio, Granada, Spain, 8Hospital Ramon y Cajal, Madrid, Spain, 9Hospital de Pontevedra, Pontevedra, Spain, 10Hospital de Cruces, Bilbao, Spain, 11Hospital Virgen de la Salud, Toledo, Spain, 12Hospital Clínico San Carlos, Madrid, 13Hospital Son Dureta, Palma de Mallorca, Spain, 14Ophthalmology Clinic Center of Caracas, Caracas, Venezuela

Outbreak in Syphilis Presenting As Uveitis
Inés Pérez-Martín1, David de la Hera1, Ricardo Blanco2, Javier Rueda1, Carmen Bejerano2, Orlando Pompei1, Joaquín Cañal1, Juan Ventosa1, Manuel Gutiérrez-Cuadra1, Vanesa Calvo1, Javier Loricera1 and Miguel Angel González-Gay1, 1Hospital Universitario Marqués de Valdecilla. IFIMAV, Santander, Spain, 2Hospital Universitario Marqués de Valdecilla-IFIMAV, Santander, Spain

Anti-TNFα Therapy in 15 Patients with Severe and Refractory Sarcoidosis
Inés Pérez-Martín1, Ricardo Blanco2, Javier Rueda1, Carmen Bejerano2, Orlando Pompei1, M. Carmen González-Vela1, Marcos A. González-López1, Héctor Fernández-Llaca1, Agustín Oterino1, María J. Sedano1, Mario Agudo1, Víctor M. Martínez-Taboada1 and Miguel Angel González-Gay1, 1Hospital Universitario Marqués de Valdecilla. IFIMAV, Santander, Spain, 2Hospital Universitario Marqués de Valdecilla-IFIMAV, Santander, Spain
Hospital Universitario Marqués de Valdecilla. IFIMAV
High Dose Intravenous Methylprednisolone Induces Rapid Improvement In Severe Uveitis: A Multicenter Study
Carmen Bejerano1, Ricardo Blanco1, Emma Beltrán2, Alejandro Fonollosa3, Olga Maiz4, Ana Blanco-Esteban4, Miguel Cordero5, Inés Pérez-Martín6, Joaquín Cañal6, Juan Ventosa6 and Miguel Angel González-Gay6, 1Hospital Universitario Marqués de Valdecilla-IFIMAV, Santander, Spain, 2Hospital Peset, Valencia, Spain, 3Hospital de Cruces, Barakaldo-Bilbao, Spain, 4Hospital Donostia, San Sebastian, Spain, 5Hospital León, León, Spain, 6Hospital Universitario Marqués de Valdecilla. IFIMAV, Santander, Spain

Adalimumab in 107 Refractory Uveitis: A Multicenter Study
Orlando Pompei1, Ricardo Blanco2, Manuel Diaz-llopis3, David Salom3, Carmen Garcia-Vicuña4, Miguel Cordero-Coma5, Gabriela Ortega-Larrocea6, Norberto Ortego-Centeno7, Marta Suarez-de-Figueroa8, J. Carlos Fernandez-Cid9, Alejandro Fonollosa10, Angel M. Garcia-Aparicio11, Jose M. Benítez-del-Castillo12, Jose L. Olea13 and J. Fernando Arevalo14, 1Hospital Universitario Marqués de Valdecilla. IFIMAV, Santander, Spain, 2Hospital Universitario Marqués de Valdecilla-IFIMAV, Santander, Spain, 3La Fe University Hospital of Valencia, Valencia, Spain, 4Hospital Sant Joan de Déu, Barcelona, Spain, 5Hospital de León, León, Spain, 6National Institute of Rehabilitation, D.F Mexico, Mexico, 7Hospital Clínico San Cecilio, Granada, Spain, 8Hospital Ramon y Cajal, Madrid, Spain, 9Hospital de Pontevedra, Pontevedra, Spain, 10Hospital de Cruces, Bilbao, Spain, 11Hospital Virgen de la Salud, Toledo, Spain, 12Hospital Clínico San Carlos, Madrid, 13Hospital Son Dureta, Palma de Mallorca, Spain, 14Ophthalmology Clinic Center of Caracas, Caracas, Venezuela

Outbreak in Syphilis Presenting As Uveitis
Inés Pérez-Martín1, David de la Hera1, Ricardo Blanco2, Javier Rueda1, Carmen Bejerano2, Orlando Pompei1, Joaquín Cañal1, Juan Ventosa1, Manuel Gutiérrez-Cuadra1, Vanesa Calvo1, Javier Loricera1 and Miguel Angel González-Gay1, 1Hospital Universitario Marqués de Valdecilla. IFIMAV, Santander, Spain, 2Hospital Universitario Marqués de Valdecilla-IFIMAV, Santander, Spain

Anti-TNFα Therapy in 15 Patients with Severe and Refractory Sarcoidosis
Inés Pérez-Martín1, Ricardo Blanco2, Javier Rueda1, Carmen Bejerano2, Orlando Pompei1, M. Carmen González-Vela1, Marcos A. González-López1, Héctor Fernández-Llaca1, Agustín Oterino1, María J. Sedano1, Mario Agudo1, Víctor M. Martínez-Taboada1 and Miguel Angel González-Gay1, 1Hospital Universitario Marqués de Valdecilla. IFIMAV, Santander, Spain, 2Hospital Universitario Marqués de Valdecilla-IFIMAV, Santander, Spain
Hospital Universitario Marques de Valdecilla. IFIMAV
Circulating B Cells Subpopulations in Patients with Antiphospholip Syndrome
Lorena Alvarez-Rodriguez1, Marcos Lopez-Hoyos1, Jaime Calvo-Alen2, Rafael Barrio del1, Orlando Pompei1 and Victor M. Martinez-Taboada3, 1Hospital Universitario Marques de Valdecilla. IFIMAV, Santander, Spain, 2Hospital Sierrallana, Torrelavega, Spain, 3Hospital Universitario Marques de Valdecilla-IFIMAV, Santander, Spain

Circulating Cytokine Profile in Patients with Antiphospholipid Syndrome
Lorena Alvarez-Rodriguez1, Marcos Lopez-Hoyos1, Jaime Calvo-Alen2, Rafael Barrio del1, Orlando Pompei1 and Victor M. Martinez-Taboada3, 1Hospital Universitario Marques de Valdecilla. IFIMAV, Santander, Spain, 2Hospital Sierrallana, Torrelavega, Spain, 3Hospital Universitario Marques de Valdecilla-IFIMAV, Santander, Spain
Hospital Universitário Pedro Ernesto
Safety Profile of Belimumab, a B-Lymphocyte Stimulator–Specific Inhibitor, in Phase 2 and 3 Clinical Trials of Patients with Active Systemic Lupus Erythematosus
D.J. Wallace1, S. Navarra2, M. Petri3, A. Gallacher4, R. Gúzman5, M. Thomas6, R.A. Furie7, O. Zamani8, R.A. Levy9, R.F. van Vollenhoven10, S. Cooper11, Z.J. Zhong11, W. Freimuth11, L. Pineda11, R. Cervera12 and BLISS-52 and -76 and LBSL02/99 Study Groups13, 1Cedars-Sinai/UCLA, Los Angeles, CA, 2University of Santo Tomas Hospital, Manila, Philippines, 3Johns Hopkins University School of Medicine, Baltimore, MD, 4Hospital Británico de Buenos Aires, Buenos Aires, Argentina, 5IDEARG, SaludCoop, Bogotá, Colombia, 6Kerala Institute of Medical Sciences, Kerala, India, 7North Shore-LIJ Health System, Lake Success, NY, 8Rheumazentrum Favoriten, Wien, Austria, 9Hospital Universitário Pedro Ernesto, Rio de Janeiro, Brazil, 10The Karolinska Institute, Stockholm, Sweden, 11Human Genome Sciences, Inc., Rockville, MD, 12Hospital Clinic, Barcelona, Spain, 13Multicenter
Hospital Universitario Virgen de la Arrixaca
Are Training Sessions Useful for Ultrasound Scan Evaluation of Synovitis In Rheumatoid Arthritis?
Andrés Ponce, Hospital General de Granollers, Granollers, Spain, Juan J. Alegre, Hospital Universitario Dr Peset, Valencia, Spain, Manuel Castaño, Hospital Universitario Virgen de la Arrixaca, Murcia, Spain, Ricardo Gutierrez-Polo, C.H. de Navarra, Pamplona, Spain, Francisco G. Jiménez-Núñez, Hospital Regional Universitario Carlos Haya., Malaga, Spain, María P. Macarrón, Hospital Clínico San Carlos, Madrid, Spain and Jesús Garrido, Facultad de Psicología.Universidad Autónoma de Madrid, Madrid, Spain
Hospital Universitario Virgen de las Nieves
The STAT4 rs7574865 Polymorphism Is Associated with Differences in Disease Activity and Disability in Patients Wirh Early Arthritis
Ana M. Ortiz1, Amalia Lamana1, Alejandro Balsa2, Blanca Rueda3, Laura Nuño2, Maria Eugenia Miranda-Carus2, María F. González-Escribano4, Miguel A. López-Nebot5, Dora Pascual-Salcedo2, Javier Martin6 and Isidoro González-Alvaro1, 1Hospital Universitario de La Princesa. IIS Princesa, Madrid, Spain, 2Hospital La Paz. IdiPaz, Madrid, Spain, 3Facultad de Ciencias de la Salud. Universidad de Granada, Granada, Spain, 4Hospital Universitario Virgen del Rocío, Sevilla, Spain, 5Hospital Universitario Virgen de las Nieves, Granada, Spain, 6Instituto de Parasitologia y Biomedicina Lopez-Neyra (CSIC), Granada, Spain
Hospital Universitario Virgen del Rocío
The STAT4 rs7574865 Polymorphism Is Associated with Differences in Disease Activity and Disability in Patients Wirh Early Arthritis
Ana M. Ortiz1, Amalia Lamana1, Alejandro Balsa2, Blanca Rueda3, Laura Nuño2, Maria Eugenia Miranda-Carus2, María F. González-Escribano4, Miguel A. López-Nebot5, Dora Pascual-Salcedo2, Javier Martin6 and Isidoro González-Alvaro1, 1Hospital Universitario de La Princesa. IIS Princesa, Madrid, Spain, 2Hospital La Paz. IdiPaz, Madrid, Spain, 3Facultad de Ciencias de la Salud. Universidad de Granada, Granada, Spain, 4Hospital Universitario Virgen del Rocío, Sevilla, Spain, 5Hospital Universitario Virgen de las Nieves, Granada, Spain, 6Instituto de Parasitologia y Biomedicina Lopez-Neyra (CSIC), Granada, Spain
Hospital Universitario Virgen Macarena
Smoking and Oxidative Stress Interaction Is Associated with Rheumatoid Arthritis Risk. A Case – Control Study
Victoria Navarro Compán, Enrique Melguizo Madrid, Blanca Hernández Cruz, Christian Leyva Prado, Teresa Arrobas Velilla, Federico Navarro Sarabia and Concepción González Rodríguez, Hospital Universitario Virgen Macarena, Sevilla, Spain
Hospital University Abbeville
Switching From Rituximab to Abatacept: Tolerance Data of 203 Patients Prospectively Followed up in the
Jacques-Eric Gottenberg, Strasbourg University Hospital, Strasbourg, France, Thierry Schaeverbeke, Pellegrin Hospital, Bordeaux, France, Philippe Gaudin, CHU Hôpital Sud, Grenoble Teaching Hospital, Echirolles, France, Liana E. Euller-Ziegler, L Archet Hospital (University), Nice CEDEX 3, France, Thao Pham, Sainte Marguerite Hospital, Marseille, France, Rene-Marc Flipo, Hopital R Salengro CHRU, Lille CEDEX, France, Alain G. Cantagrel, Hopital Purpan, Toulouse CEDEX 9, France, Eric Houvenagel, St Philibert Hospital, Lomme 59462, France, S. Redecker, Hospital University Abbeville, France, Xavier X. Le Loet, CHU de ROUEN, Rouen CEDEX, France, Pascal Claudepierre, Université Paris Est, Laboratoire d'Investigation Clinique (LIC) EA 4393, AP-HP, Hôpital Henri-Mondor, Rheumatology department, Creteil, France, Isabelle Pane, France, Philippe Ravaud, Hopital Hotel Dieu, Paris Descartes University, Paris, France and Xavier Mariette, Université Paris-Sud, Le Kremlin Bicetre, France
Hospital University Bobigny
Serum IL-21 Is Increased and Associated with Higher Disease Activity and Higher Serum Levels of Markers of B-Cell Activation in Primary Sjögren's Syndrome
Jacques-Eric Gottenberg1, Ghada Alsaleh1, Corinne Miceli-Richard2, Raphaèle Seror3, Joelle Benessiano4, Valerie Devauchelle-Pensec5, Philippe Dieude6, Jean Jacques Dubost7, Anne-Laure Fauchais8, Vincent Goeb9, Eric Hachulla10, Pierre yves Hatron11, C. Larroche12, Véronique Le Guern13, Jacques Morel14, Aleth Perdriger15, Xavier Puechal16, Stephanie Rist17, Alain Saraux18, Damien Sène19, Jean Sibilia20, Karine Inamo21, Philippe Ravaud22 and Xavier Mariette23, 1Strasbourg University Hospital, Strasbourg, France, 2Hopital Bicêtre, Le Kremlin Bicêtre, France, 3Bicetre university hospital, LE Kremlin-Bicetre, France, 4Rheumatology, Paris Unervisity Hospital BICHAT, France, 5Brest Occidentale university, Brest, France, 6APHP, Hopital Bichat, Paris, France, 7CHU Gabriel Montpied, Clermont-Ferrand, France, 8Hospital, Limoges, France, 9Rheumatology, Rouen Unervisity Hospital, France, France, 10Internal Medicine, Lille CEDEX, France, 11Service de médecine interne, Hôpital Claude Huriez, Université Lille II, Lille, France, Paris, France, 12Hospital University Bobigny, France, 13Cochin Hospital, Paris, France, 14Hopital Lapeyronie, Montpellier, France, 15Hôpital Sud, Rennes, France, 16Le Mans General Hospital, Le Mans, France, 17Hospital University Orléans, France, 18CHU de la Cavale Blanche, Brest Cedex, France, 19Pitie-Salpetriere Hospital, Paris, France, 20Service de rhumatologie, Hôpitaux Universitaires de Strasbourg, Strasbourg, France, Strasbourg, France, 21Nihon Univ Hikarigoaka Hosp, Nerima-ku Tokyo, Japan, 22Hopital Hotel Dieu, Paris Descartes University, Paris, France, 23Université Paris-Sud, Le Kremlin Bicetre, France

Results of a Randomized Controlled Study of Adalimumab for Steroid Sparing in Patients with Giant-Cell Arteritis
Xavier Mariette, Université Paris-Sud, Le Kremlin Bicetre, France, Gabriel Baron, Epidemiology, Paris, France, Eric Hachulla, Internal Medicine, Lille CEDEX, France, Michel DeBandt, Abstract Medical Int'l, Boulogne, France, C. Larroche, Hospital University Bobigny, France, Xavier Puéchal, Le Mans General Hospital, Le Mans, France, Francois Maurier, Division of internal Medicine, CHR Metz, Metz, Metz, France, B. de Wazieres, CHU de Nimes, Nimes, France, T. Quemeneur, CHR de Valenciennes, Valenciennes, France and Philippe Ravaud, Hopital Hotel Dieu, Paris Descartes University, Paris, France
Hospital University Orléans
Serum IL-21 Is Increased and Associated with Higher Disease Activity and Higher Serum Levels of Markers of B-Cell Activation in Primary Sjögren's Syndrome
Jacques-Eric Gottenberg1, Ghada Alsaleh1, Corinne Miceli-Richard2, Raphaèle Seror3, Joelle Benessiano4, Valerie Devauchelle-Pensec5, Philippe Dieude6, Jean Jacques Dubost7, Anne-Laure Fauchais8, Vincent Goeb9, Eric Hachulla10, Pierre yves Hatron11, C. Larroche12, Véronique Le Guern13, Jacques Morel14, Aleth Perdriger15, Xavier Puechal16, Stephanie Rist17, Alain Saraux18, Damien Sène19, Jean Sibilia20, Karine Inamo21, Philippe Ravaud22 and Xavier Mariette23, 1Strasbourg University Hospital, Strasbourg, France, 2Hopital Bicêtre, Le Kremlin Bicêtre, France, 3Bicetre university hospital, LE Kremlin-Bicetre, France, 4Rheumatology, Paris Unervisity Hospital BICHAT, France, 5Brest Occidentale university, Brest, France, 6APHP, Hopital Bichat, Paris, France, 7CHU Gabriel Montpied, Clermont-Ferrand, France, 8Hospital, Limoges, France, 9Rheumatology, Rouen Unervisity Hospital, France, France, 10Internal Medicine, Lille CEDEX, France, 11Service de médecine interne, Hôpital Claude Huriez, Université Lille II, Lille, France, Paris, France, 12Hospital University Bobigny, France, 13Cochin Hospital, Paris, France, 14Hopital Lapeyronie, Montpellier, France, 15Hôpital Sud, Rennes, France, 16Le Mans General Hospital, Le Mans, France, 17Hospital University Orléans, France, 18CHU de la Cavale Blanche, Brest Cedex, France, 19Pitie-Salpetriere Hospital, Paris, France, 20Service de rhumatologie, Hôpitaux Universitaires de Strasbourg, Strasbourg, France, Strasbourg, France, 21Nihon Univ Hikarigoaka Hosp, Nerima-ku Tokyo, Japan, 22Hopital Hotel Dieu, Paris Descartes University, Paris, France, 23Université Paris-Sud, Le Kremlin Bicetre, France
Hospital Vall de Hebró, Grup de Recerca de Reumatologia
Synovial Tissue Cytokine Expression in Rheumatoid Arthritis and Associations with Lymphoid Neogenesis, Disease Activity and the European League Against Rheumatism Response
Juan D. Canete1, Raquel Celis2, Julio Ramirez1, Sara Marsal3, Gabriel Avila3, Raimon Sanmarti2 and Jose L. Pablos4, 1Hospital Clinic, Barcelona, Spain, 2Clinic Hospital, Barcelona, Spain, 3Hospital Vall de Hebró, Grup de Recerca de Reumatologia, Barcelona, Spain, 4Instituto de Investigación Hospital 12 de Octubre (I+12), Madrid, Spain
Hospital Valle de Hebron
A Genome-Wide Association Study Follow-up Strategy Reveals the Association of IL12RB2 Gene with Systemic Sclerosis in Caucasian Populations
Lara Bossini-Castillo1, Jose Ezequiel Martin1, Jasper Broen2, Carmen Pilar Simeon3, Lorenzo Beretta4, Madelon C. Vonk2, Patricia E. Carreira5, Spanish Scleroderma Group, Gabriela Riemekasten7, Nicolas Hunzelmann8, Alexandre E. Voskuyl9, Annemie Schuerwegh10, Oyvind Palm11, Roger Hesselstrand12, Annika Nordin13, Claudio Lunardi14, Paul Shiels15, Jacob M. van Laar16, Ariane L. Herrick17, Filemon K. Tan18, Shervin Assassi19, Carmen Fonseca20, Maureen D. Mayes18, Timothy Radstake2 and Javier Martin1, 1Instituto de Parasitología y Biomedicina López-Neyra, IPBLN-CSIC, Granada, Spain, 2Radboud University Nijmegen Medical Centre, Nijmegen, Nijmegen, Netherlands, 3Hospital Valle de Hebron, Barcelona, Spain, 4IRCCS Fondazione Policlinico-Mangiagalli-Regina Elena & University of Milan, Milan, Italy, 5Instituto de Investigación Hospital 12 de Octubre (I+12), Madrid, Spain, 6Charité University Hospital, German Rheumatology Research Center, a Leibniz Institute, Berlin, Germany, 7University of Cologne, Cologne, Germany, 8VU University Medical Center, Amsterdam, Netherlands, 9Leids Univ Medisch Centrum, Leiden, Netherlands, 10Rikshospitalet, Oslo University Hospital, Oslo, Norway, 11Lund University & Skåne University Hopsital, Lund, Sweden, 12Karolinska Institute, Stockholm, Sweden, 13Policlinico G B Rossi, Verona, Italy, 14University of Glasgow, Glasgow, United Kingdom, 15Musculoskeletal Research Group, Newcastle, United Kingdom, 16Rheumatic Diseases Centre, Salford, United Kingdom, 17University of Texas Health Science Center at Houston, Houston, TX, 18Univ of Texas Health Science, Houston, TX, 19Royal Free and University College Medical School, London, United Kingdom

The IRF7 Region Is Associated with Anti-Centromere Autoantibody Production in Systemic Sclerosis Patients
F. David Carmona1, Ramana Gutala2, Carmen P. Simeón3, Patricia E. Carreira4, Norberto Ortego-Centeno5, Esther Vicente-Rabaneda6, Francisco J. García-Hernández7, Paloma García de la Peña8, Mónica Fernández-Castro9, Lina Martínez-Estupiñán10, María-Victoria Egurbide11, Spanish Scleroderma Group, Betty P. Tsao13, Pravitt R. Gourh14, Sandeep K. Agarwal15, Shervin Assassi16, Maureen D. Mayes15, Frank C. Arnett15, Filemon K. Tan15 and Javier Martín17, 1Consejo Superior de Investigaciones Científicas, Armilla (Granada), Spain, 2The University of Texas Health Science Center, Houston, TX, 3Hospital Valle de Hebron, Barcelona, Spain, 4Instituto de Investigación Hospital 12 de Octubre (I+12), Madrid, Spain, 5Hospital Clínico San Cecilio, Granada, Spain, 6Hospital de la Princesa, Madrid, Spain, 7Hospital Virgen del Rocío, Sevilla, Spain, 8Hospital Universitario Madrid Norte Sanchinarro, Madrid, Spain, 9Hospital Puerta de Hierro, Madrid, Spain, 10Gregorio Marañón Hospital, Madrid, Spain, 11Hospital de Cruces, UPV/EHU, Barakaldo, Spain, Barakaldo, Spain, 12David Geffen School of Medicine University of California Los Angeles, Los Angeles, CA, 13UTHSC-Houston Medical School, Houston, TX, 14University of Texas Health Science Center at Houston, Houston, TX, 15Univ of Texas Health Science, Houston, TX, 16Consejo Superior de Investigaciones Científicas, Granada, Spain

Immunochip Genotyping of 1,884 Systemic Sclerosis Cases and 4,325 Controls Reveals Novel Associations
Maureen D. Mayes1, Olga Y. Gorlova2, Lara Bossini-Castillo3, Jose Ezequiel Martin4, Jun Ying2, Peter K. Gregersen5, Annette T. Lee6, Shervin Assassi1, Sandeep K. Agarwal1, Filemon K. Tan1, John D. Reveille1, Xiaodong Zhou1, Frank C. Arnett1, Fredrick M. Wigley7, Laura K. Hummers7, Marilyn Perry1, Carmen Pilar Simeon8, Patricia Carriera9, Norberto Ortego-Centeno10, Miguel Gonzalez-Gay11, the Spanish Scleroderma Group12 and Javier Martin13, 1University of Texas Health Science Center at Houston, Houston, TX, 2UT M. D. Anderson Cancer Center, Houston, TX, 3Consejo Superior de Investigaciones Científicas (CSIC), Armilla (Granada), Spain, 4Instituto de Parasitología y Biomedicina López-Neyra, IPBLN-CSIC, Armilla (Granada), Spain, 5Feinstein Institute Medical Reschearch, Manhasset, NY, 6Feinstein Institute Med Rsch, Manhasset, NY, 7Johns Hopkins University, Baltimore, MD, 8Hospital Valle de Hebron, Barcelona, Spain, 9Madrid, Spain, 10Hospital Clínico San Cecilio, Granada, Spain, 11Hospital Marques De Valdecilla, Santander, Spain, 12Granada, Spain, 13Instituto de Parasitologia y Biomedicina Lopez-Neyra (CSIC), Granada, Spain
Hospital Virgen de la Salud
Adalimumab in 107 Refractory Uveitis: A Multicenter Study
Orlando Pompei1, Ricardo Blanco2, Manuel Diaz-llopis3, David Salom3, Carmen Garcia-Vicuña4, Miguel Cordero-Coma5, Gabriela Ortega-Larrocea6, Norberto Ortego-Centeno7, Marta Suarez-de-Figueroa8, J. Carlos Fernandez-Cid9, Alejandro Fonollosa10, Angel M. Garcia-Aparicio11, Jose M. Benítez-del-Castillo12, Jose L. Olea13 and J. Fernando Arevalo14, 1Hospital Universitario Marqués de Valdecilla. IFIMAV, Santander, Spain, 2Hospital Universitario Marqués de Valdecilla-IFIMAV, Santander, Spain, 3La Fe University Hospital of Valencia, Valencia, Spain, 4Hospital Sant Joan de Déu, Barcelona, Spain, 5Hospital de León, León, Spain, 6National Institute of Rehabilitation, D.F Mexico, Mexico, 7Hospital Clínico San Cecilio, Granada, Spain, 8Hospital Ramon y Cajal, Madrid, Spain, 9Hospital de Pontevedra, Pontevedra, Spain, 10Hospital de Cruces, Bilbao, Spain, 11Hospital Virgen de la Salud, Toledo, Spain, 12Hospital Clínico San Carlos, Madrid, 13Hospital Son Dureta, Palma de Mallorca, Spain, 14Ophthalmology Clinic Center of Caracas, Caracas, Venezuela
Hospital Virgen del Rocío
Biologics use in SLE in 23 Centers - Data from the International Registry for Biologics In SLE (IRBIS)
R.F. van Vollenhoven1, Søren Jacobsen2, Daniel Wallace3, John G. Hanly4, Michelle Petri5, David A. Isenberg6, Sasha Bernatsky7, Sang-Cheol Bae8, Manuel Ramos-Casals9, Guillermo Ruiz-Irastorza10, Francisco J. García-Hernández11, Luis Saez12, José Luis Callejas13, Javier Rascón14, Enrique de Ramón15, Mª Mar Ayala-Gutiérrez15, Maite Camps15, Melinda Mild16, Murat Inanç17, Bahar Artim-Esen17, Rosalind Ramsey-Goldman18, Christine A. Peschken19, Danilo Squatrito20, László Kovács21, Andrea Doria22, Zoltan Szekanecz23, Elisa Gremese24 and Emilia I. Sato25, 1Karolinska University Hospital, Stockholm, Sweden, 2Copenhagen University Hospital, Copenhagen, Denmark, 3Cedars-Sinai/UCLA, Los Angeles, CA, 4Dalhousie University and Capital Health, Halifax, NS, 5Johns Hopkins Hospital, Baltimore, MD, 6University College London, London, United Kingdom, 7McGill UHC/RVH, Montreal, QC, 8Hanyang University Hospital for Rheumatic Diseases, Seoul, South Korea, 9Hospital Clínic, Barcelona, Spain, 10Hospital de Cruces, Bizkaia, Spain, 11Hospital Virgen del Rocío, Sevilla, Spain, 12Hospital Miguel Servet, Zaragoza, Spain, 13Hospital San Cecilio, Granada, Spain, 14Hospital Son Dureta, Palma de Mallorca, Spain, 15Hospital Carlos Haya, Málaga, Spain, 16Karolinska Institutet, Stockholm, Sweden, 17Istanbul University, Istanbul Medical Faculty, Istanbul, Turkey, 18Northwestern University Feinberg School of Medicine, Chicago, IL, 19Univ of Manitoba, Winnipeg, MB, 20Careggi Hospital- Florence, Florence, Italy, 21University of Szeged, Szeged, Hungary, 22University of Padova, Padova, Italy, 23University of Debrecen Medical and Health Sciences Center, Debrecen, Hungary, 24Rheumatology Unit, Catholic University, Roma, Italy, 25Escola Paulista de Medicina - Universidade Federal de São Paulo, Sao Paulo, Brazil

The IRF7 Region Is Associated with Anti-Centromere Autoantibody Production in Systemic Sclerosis Patients
F. David Carmona1, Ramana Gutala2, Carmen P. Simeón3, Patricia E. Carreira4, Norberto Ortego-Centeno5, Esther Vicente-Rabaneda6, Francisco J. García-Hernández7, Paloma García de la Peña8, Mónica Fernández-Castro9, Lina Martínez-Estupiñán10, María-Victoria Egurbide11, Spanish Scleroderma Group, Betty P. Tsao13, Pravitt R. Gourh14, Sandeep K. Agarwal15, Shervin Assassi16, Maureen D. Mayes15, Frank C. Arnett15, Filemon K. Tan15 and Javier Martín17, 1Consejo Superior de Investigaciones Científicas, Armilla (Granada), Spain, 2The University of Texas Health Science Center, Houston, TX, 3Hospital Valle de Hebron, Barcelona, Spain, 4Instituto de Investigación Hospital 12 de Octubre (I+12), Madrid, Spain, 5Hospital Clínico San Cecilio, Granada, Spain, 6Hospital de la Princesa, Madrid, Spain, 7Hospital Virgen del Rocío, Sevilla, Spain, 8Hospital Universitario Madrid Norte Sanchinarro, Madrid, Spain, 9Hospital Puerta de Hierro, Madrid, Spain, 10Gregorio Marañón Hospital, Madrid, Spain, 11Hospital de Cruces, UPV/EHU, Barakaldo, Spain, Barakaldo, Spain, 12David Geffen School of Medicine University of California Los Angeles, Los Angeles, CA, 13UTHSC-Houston Medical School, Houston, TX, 14University of Texas Health Science Center at Houston, Houston, TX, 15Univ of Texas Health Science, Houston, TX, 16Consejo Superior de Investigaciones Científicas, Granada, Spain
Hospital “12 de Octubre”
Utility of the Systemic Lupus International Collaborating Clinics (SLICC)/American College of Rheumatology (ACR) Damage Index for Antiphospholipid Antibody (aPL) Positive Patients
Medha Barbhaiya1, Doruk Erkan2, Esther Rodriguez-Almaraz3, Glendalee Ramon4, JoAnn Vega4 and Michael D. Lockshin4, 1Weill Cornell Medical Center, New York, NY, 2Barbara Volcker Center for Women and Rheumatic Diseases, Hospital for Special Surgery, New York, NY, 3Hospital “12 de Octubre”, Madrid, Spain, 4Barbara Volcker Center for Women and Rheumatic Diseases: Hospital for Special Surgery, New York, NY
Hospital-Beau-Sejour
Some Clinical Features Are Associated with MODIC I Changes in Patient with Chronic Low Back pain ; Results of a Case Control Study
Florian Bailly1, Jean-Yves Maigne2, Stéphane Genevay3, Marc Marty4, Frédérique Gandjbakhch1, Sylvie Rozenberg5 and Violaine Foltz6, 1Hopital Pitié Salpétrière, Paris, France, 2Hôpital Hôtel Dieu, Paris, France, 3Hospital-Beau-Sejour, Geneva, Switzerland, 4Hôpital Henri Mondor, Créteil, France, 5Hopital La Pitie, Paris, France, 6Hôpital Pitié Salpétrière, Paris, France
Hosptial Universitario Severo Ochoa
Application of Ultrasound to Treat to Target Management of Rheumatoid Arthritis  - Multicentre International Observational Experience
Sibel Aydin1, Maya H. Buch2, Sarah Horton3, Kei Ikeda4, Annamaria Iagnocco5, Marwin Gutierrez6, Walter Grassi7, Esperanza Naredo8, Eugenio De Miguel9, Lene Terslev10, Marina Backhaus11, Maria-Antonietta D'Agostino12, Alberto Batticciotto2, Zunaid Karim2, Richard J. Wakefield13 and Paul Emery14, 1Goztepe Training and Research Hospital, Istanbul, Turkey, 2Leeds institute of Molecular Medicine, University of Leeds and NIHR Leeds Musculoskeletal Disease Biomedical Research Unit, Leeds Teaching Hospitals, Leeds, United Kingdom, 3Leeds institute of Molecular Medicine, University of Leeds and NIHR Leeds Musculoskeletal Disease Biomedical Research Unit, Leeds Teaching Hospitals, United Kingdom, 4Chiba University Hospital, Chiba, Japan, 5Uni, Jesi, Italy, 6Sapienza Universita di Roma, Rome, Italy, 7Università Politecnica delle Marche, Jesi, Italy, 8Hosptial Universitario Severo Ochoa, Madrid, Spain, 9La Paz University Hospital, Madrid, Spain, 10The Parker Institute, Copenhagen, Denmark, 11Charite University Hospital, Berlin, Germany, 12Versailles-Saint Quentin en Yvelines University- APHP, Ambroise-Paré Hospital, Boulogne-Billancourt, France, 13Leeds Institute of Molecular Medicine, University of Leeds and NIHR Leeds Musculoskeletal Biomedical Research Unit, Leeds Teaching Hospitals, Leeds, United Kingdom, 14Chapel Allerton Hospital, Leeds, United Kingdom

Ultrasound Findings in Rheumatology
Esperanza Naredo, Hosptial Universitario Severo Ochoa, Madrid, Spain







Hotel Dieu University hospital
Comparative Effectiveness of Rituximab and Abatacept in 1192 Patients with Rheumatoid Arthritis Included in the French Society of Rheumatology AIR and ORA Registries
Jacques-Eric Gottenberg, Strasbourg University Hospital, Strasbourg, France, Philippe Ravaud, Hotel Dieu University hospital, France, Thomas Bardin, Service de Rhumatologie. Centre Viggo Petersen. Hôpital Lariboisiere, Paris, France, Patrice Cacoub, CHU Pitié-Salpêtrière, Paris, France, Alain G. Cantagrel, Hopital Purpan, Toulouse CEDEX 9, France, Bernard G. Combe, Hopital Lapeyronie, Montpellier, France, Maxime Dougados, Paris-Descartes University, Cochin Hospital, Paris, France, Rene-Marc Flipo, Hopital R Salengro CHRU, Lille CEDEX, France, Bertrand Godeau, Service de médecine interne, Université Paris Est Créteil, AP-HP, Hôpital Mondor Créteil, France, Creteil, France, Loic Guillevin, Cochin University Hospital, Paris, France, Xavier X. Le Loet, CHU de ROUEN, Rouen CEDEX, France, Eric Hachulla, Internal Medicine, Lille CEDEX, France, Thierry Schaeverbeke, Pellegrin Hospital, Bordeaux, France, Jean Sibilia, Service de rhumatologie, Hôpitaux Universitaires de Strasbourg, Strasbourg, France, Strasbourg, France, Isabelle Pane, France, Gabriel Baron, Epidemiology, Paris, France and Xavier Mariette, Université Paris-Sud, Le Kremlin Bicetre, France

Low Serum IgG Level After Rituximab Is Associated with An Increased Risk of Serious Infections in Rheumatoid Arthritis: Data of the AIR Registry
Jacques-Eric Gottenberg1, Philippe Ravaud2, Thomas Bardin3, Patrice Cacoub4, Alain G. Cantagrel5, Bernard G. Combe6, Maxime Dougados7, Rene-Marc Flipo8, Bertrand Godeau9, Loic Guillevin10, Xavier X. Le Loet11, Eric Hachulla12, Thierry Schaeverbeke13, Jean Sibilia14, Isabelle Pane15, Adelina Abbe15, Gabriel Baron16 and Xavier Mariette17, 1Strasbourg University Hospital, Strasbourg, France, 2Hotel Dieu University hospital, France, 3Service de Rhumatologie. Centre Viggo Petersen. Hôpital Lariboisiere, Paris, France, 4CHU Pitié-Salpêtrière, Paris, France, 5Hopital Purpan, Toulouse CEDEX 9, France, 6Hopital Lapeyronie, Montpellier, France, 7Paris-Descartes University, Cochin Hospital, Paris, France, 8Hopital R Salengro CHRU, Lille CEDEX, France, 9Service de médecine interne, Université Paris Est Créteil, AP-HP, Hôpital Mondor Créteil, France, Creteil, France, 10Cochin University Hospital, Paris, France, 11CHU de ROUEN, Rouen CEDEX, France, 12Internal Medicine, Lille CEDEX, France, 13Pellegrin Hospital, Bordeaux, France, 14Service de rhumatologie, Hôpitaux Universitaires de Strasbourg, Strasbourg, France, Strasbourg, France, 15France, 16Epidemiology, Paris, France, 17Université Paris-Sud, Le Kremlin Bicetre, France
Hotel-Dieu
Giant Cell Arteritis with or without Suspicion of Aortitis At Diagnosis. A Retrospective Study of 22 Patients with a 12-Year Follow-up
Olivier Espitia1, Antoine Néel1, Christophe Leux2, Jerome Connault3, Thierry D. Ponge4, Benoît Dupas2, Mohamed Hamidou3 and Christian Agard1, 1Internal Medicine, Nantes University Hospital, Nantes, France, 2Nantes University Hospital, Nantes, France, 3Service de médecine interne, Hôpital Universitaire de Nantes, Nantes, France, Nantes, France, 4Hotel-Dieu, Nantes CEDEX 1, France
Howard University Hospital
Ethnic Minority Rheumatoid Arthritis Consortium: A Clinical Registry of Minority Patients with Rheumatoid Arthritis
Gail S. Kerr1, Yvonne R. S. Sherrer2, Raj G. Nair3, Edward L. Treadwell4, Angelia D. Mosley-Williams5, Asia M. Mubashir6, Luis R. Espinoza7, Jeffrey Huang6, Christopher Swearingen8 and Yusuf Yazici9, 1Washington DC VAMC and Georgetown University and Howard University Hospital, Washington, DC, 2Centre Rheum Immunol Arthritis, Fort Lauderdale, FL, 3Washington Hospital Center, Washington, DC, 4E Carolina Univ Sch of Med, Greenville, NC, 5John Dingell VAMC, Detroit, MI, 6Howard University Hospital, Washington, DC, 7LSU Medical Center, New Orleans, LA, 8University of Arkansas for Medical Sciences, Little Rock, AR, 9Division of Rheumatology, New York University School of Medicine and NYU Hospital for Joint Diseases, New York, NY

Disease Activity Levels and Treatment Patterns Amongst Ethnic Minority Rheumatoid Arthritis Consortium Patients
Yusuf Yazici1, Christopher Swearingen2, Yvonne R. S. Sherrer3, Raj G. Nair4, Edward L. Treadwell5, Angelia D. Mosley-Williams6, Luis R. Espinoza7, Asia M. Mubashir8, Jeffrey Huang8 and Gail S. Kerr9, 1Division of Rheumatology, New York University School of Medicine and NYU Hospital for Joint Diseases, New York, NY, 2University of Arkansas for Medical Sciences, Little Rock, AR, 3Centre Rheum Immunol Arthritis, Fort Lauderdale, FL, 4Washington Hospital Center, Washington DC, DC, 5E Carolina Univ Sch of Med, Greenville, NC, 6John Dingell VAMC, Detroit, MI, 7LSU Medical Center, New Orleans, LA, 8Howard University Hospital, Washington, DC, 9Washington DC VAMC and Georgetown University and Howard University Hospital, Washington, DC
HU
Response to Local Corticosteroid Injection In Carpal Tunnel Syndrome with Normal Electrodiagnostic Study
Domingo Ly-Pen1, José Luis Andreu2, Isabel Millán3, Gema de Blas4 and Alberto Sánchez-Olaso4, 1SERMAS. CS "Gandhi" / Hospital "Ramón y Cajal", Madrid, Spain, 2HU, Madrid, Spain, 3HU "Puerta de Hierro Majadahonda", Madrid, Spain, 4Hospital "Ramón y Cajal", Madrid, Spain
HU "Puerta de Hierro Majadahonda"
Response to Local Corticosteroid Injection In Carpal Tunnel Syndrome with Normal Electrodiagnostic Study
Domingo Ly-Pen1, José Luis Andreu2, Isabel Millán3, Gema de Blas4 and Alberto Sánchez-Olaso4, 1SERMAS. CS "Gandhi" / Hospital "Ramón y Cajal", Madrid, Spain, 2HU, Madrid, Spain, 3HU "Puerta de Hierro Majadahonda", Madrid, Spain, 4Hospital "Ramón y Cajal", Madrid, Spain
Huashan Hospital
All-Trans Retinoic Acid Sustains the Stability and Function of Natural Regulatory T Cells From Human and Patients with SLE
Qin Lan1, Julie Wang1, Hui-Ming Fan2, David Brand3, Hejian Zou4, Zhong-Min Liu2 and Song G. Zheng1, 1University of Southern California, Los Angeles, CA, 2Shanghai East Hospital, Tonji University, Shanghai, China, 3VA Medical Center, Memphis, TN, 4Huashan Hospital, Shanghai, China

Therapeutic Effects of TGF-β-Induced Regulatory T Cells on the Established Autoimmune Diseases
Song G. Zheng1, Qin Lan2, Julie Wang2, David Brand3, David A. Horwitz4, Zhong-Min Liu5 and Hejian Zou6, 1USC Keck School of Medicine, Los Angeles, CA, 2University of Southern California, Los Angeles, CA, 3VA Medical Center, Memphis, TN, 4USC School of Medicine, Los Angeles, CA, 5Shanghai East Hospital, Tonji University, Shanghai, China, 6Huashan Hospital, Shanghai, China

Decreased Interleukin-22 in Pulmonary Fibrosis: Potential Role As a Regulatory Cytokine
Minrui Liang1, Xiangjun Chen2, Jiu-Cun Wang3, Min Guan2, Haiyan Chu4 and Hejian Zou5, 1Huashan Hospital,Fudan University,Shanghai, Shanghai, China, 2Huashan Hospital, Fudan University, Shanghai, China, 3Fudan University, Shanghai, China, 4School of Life Science, Fudan University, China, 5Huashan Hospital, Shanghai, China
Huashan Hospital, Fudan University
Decreased Interleukin-22 in Pulmonary Fibrosis: Potential Role As a Regulatory Cytokine
Minrui Liang1, Xiangjun Chen2, Jiu-Cun Wang3, Min Guan2, Haiyan Chu4 and Hejian Zou5, 1Huashan Hospital,Fudan University,Shanghai, Shanghai, China, 2Huashan Hospital, Fudan University, Shanghai, China, 3Fudan University, Shanghai, China, 4School of Life Science, Fudan University, China, 5Huashan Hospital, Shanghai, China
Huashan Hospital,Fudan University,Shanghai
Decreased Interleukin-22 in Pulmonary Fibrosis: Potential Role As a Regulatory Cytokine
Minrui Liang1, Xiangjun Chen2, Jiu-Cun Wang3, Min Guan2, Haiyan Chu4 and Hejian Zou5, 1Huashan Hospital,Fudan University,Shanghai, Shanghai, China, 2Huashan Hospital, Fudan University, Shanghai, China, 3Fudan University, Shanghai, China, 4School of Life Science, Fudan University, China, 5Huashan Hospital, Shanghai, China
Human Genome Sciences
Dispensability of APRIL to Development of Systemic Lupus Erythematosus (SLE) In SLE-Prone NZM 2328 Mice
Chaim O. Jacob1, Shunhua Guo1, Noam Jacob1, Rahul Pawar2, Chaim Putterman3, William J. Quinn III4, Michael P. Cancro4, Thi-Sau Migone5 and William Stohl1, 1University of Southern California Keck School of Medicine, Los Angeles, CA, 2Albert Einstein College of Med, Bronx, NY, 3Albert Einstein College of Medicine, Bronx, NY, 4University of Pennsylvania School of Medicine, Philadelphia, PA, 5Human Genome Sciences, Rockville, MD
Human Genome Sciences, Inc.
Safety Profile of Belimumab, a B-Lymphocyte Stimulator–Specific Inhibitor, in Phase 2 and 3 Clinical Trials of Patients with Active Systemic Lupus Erythematosus
D.J. Wallace1, S. Navarra2, M. Petri3, A. Gallacher4, R. Gúzman5, M. Thomas6, R.A. Furie7, O. Zamani8, R.A. Levy9, R.F. van Vollenhoven10, S. Cooper11, Z.J. Zhong11, W. Freimuth11, L. Pineda11, R. Cervera12 and BLISS-52 and -76 and LBSL02/99 Study Groups13, 1Cedars-Sinai/UCLA, Los Angeles, CA, 2University of Santo Tomas Hospital, Manila, Philippines, 3Johns Hopkins University School of Medicine, Baltimore, MD, 4Hospital Británico de Buenos Aires, Buenos Aires, Argentina, 5IDEARG, SaludCoop, Bogotá, Colombia, 6Kerala Institute of Medical Sciences, Kerala, India, 7North Shore-LIJ Health System, Lake Success, NY, 8Rheumazentrum Favoriten, Wien, Austria, 9Hospital Universitário Pedro Ernesto, Rio de Janeiro, Brazil, 10The Karolinska Institute, Stockholm, Sweden, 11Human Genome Sciences, Inc., Rockville, MD, 12Hospital Clinic, Barcelona, Spain, 13Multicenter

Sustained Disease Improvement and Safety Profile Over the 1500 Patient-Year Experience (6 years) with Belimumab in Patients with Systemic Lupus Erythematosus 
J.T. Merrill1, R.A. Furie2, D.J. Wallace3, W. Stohl4, W. Winn Chatham5, A. Weinstein6, J. Mckay7, E.M. Ginzler8, Z.J. Zhong9, L. Pineda9, J. Klein9, W. Freimuth9, M. Petri10 and LBSL02/99 Study Group11, 1Oklahoma Medical Research Foundation, Oklahoma City, OK, 2North Shore-LIJ Health System, Lake Success, NY, 3Cedars-Sinai/UCLA, Los Angeles, CA, 4USC/Keck School of Medicine, Los Angeles, CA, 5University of Alabama at Birmingham, Birmingham, AL, 6Washington Hospital Center, Washington, DC, 7Oklahoma State University Center for Health Sciences, Tulsa, OK, 8SUNY Downstate Medical Center, Brooklyn, NY, 9Human Genome Sciences, Inc., Rockville, MD, 10Johns Hopkins University School of Medicine, Baltimore, MD, 11Multicenter

Post Hoc British Isles Lupus Assessment Group Index Mucocutaneous Organ Domain Item Analysis of Systemic Lupus Erythematosus Patients Treated in Phase 3 Belimumab Clinical Trials
Susan Manzi1, Dafna Gladman2, Sandra Navarra3, Jorge Sanchez-Guerrero4, David D'Cruz5, William Freimuth6, Z. John Zhong6, Greg Keenan6 and BLISS-52 and BLISS-76 Study Groups7, 1Allegheny Singer Research Institute, Pittsburgh, PA, 2Toronto Western Hospital, Toronto, ON, 3University of Santo Tomas Hospital, Manila, Philippines, 4Mount Sinai Hospital/University Health Network, Toronto, ON, 5St. Thomas' Hospital, London, United Kingdom, 6Human Genome Sciences, Inc., Rockville, MD, 7Multicenter

Clinical and Laboratory Correlates in Responders (by the Systemic Lupus Erythematosus Responder Index) in Phase 3 Belimumab Clinical Trials
R.A. Furie1, Z.J. Zhong2, W. Freimuth2 and M. Petri3, 1North Shore-LIJ Health System, Lake Success, NY, 2Human Genome Sciences, Inc., Rockville, MD, 3Johns Hopkins University School of Medicine, Baltimore, MD

Responders in the Phase 3 Belimumab Clinical Trials in Patients with Systemic Lupus Erythematosus Reported Improvements in Fatigue and Health-Related Quality of Life At Week 52
V. Strand1, S. Cooper2, Z.J. Zhong2 and G. Dennis2, 1Stanford University, Palo Alto, CA, 2Human Genome Sciences, Inc., Rockville, MD

Factors Associated with Belimumab Treatment Benefit: Results From Phase 3 Studies in Patients with Systemic Lupus Erythematosus
R.F. van Vollenhoven1, M. Petri2, R. Cervera3, C. Kleoudis4, Z.J. Zhong5, D. Roth6, W. Freimuth5 and BLISS-52 and BLISS-76 Study Groups7, 1The Karolinska Institute, Stockholm, Sweden, 2Johns Hopkins University School of Medicine, Baltimore, MD, 3Hospital Clinic, Barcelona, Spain, 4GlaxoSmithKline, Durham, NC, 5Human Genome Sciences, Inc., Rockville, MD, 6GlaxoSmithKline, King of Prussia, PA, 7Multicenter

Effect of Belimumab Treatment on Renal Outcomes: Results From Phase 3 Belimumab Clinical Trials in Patients with Systemic Lupus Erythematosus
M.A. Dooley1, F. Houssiau2, C. Aranow3, D.P. D'Cruz4, Anca D. Askanase5, D. Roth6, Z.J. Zhong7, W. Freimuth7, E.M. Ginzler8 and BLISS-52/-76 Study Groups9, 1University of North Carolina at Chapel Hill, Chapel Hill, NC, 2Université catholique de Louvain, Brussels, Belgium, 3Feinstein Institute for Medical Research, Manhasset, NY, 4St. Thomas' Hospital, London, United Kingdom, 5NYU School of Medicine, New York, NY, 6GlaxoSmithKline, King of Prussia, PA, 7Human Genome Sciences, Inc., Rockville, MD, 8SUNY-Downstate Medical Center, Brooklyn, NY, 9Multicenter
Hutchison Medipharma Limited
HM-018, An Oral Small Molecule JAK Inhibitor, Ameliorates Experimental Autoimmune Encephalomyelitis (EAE) in Mice
Yu Cai1, Wuzhong Shen1, Qianqian Dong1, Zhipeng Wu1, Xiaoning Yang1, Ping Ren1, Youjun Yu1, Hongxia Shen1, Jia Li1, Jian Wang1, Yang Sai1, James Yan1, Wei Deng1, Jianguo Ji2, Weiguo Su1 and Haoran Zhao1, 1Hutchison Medipharma Limited, Shanghai, China, 2Abott, Shanghai, China

A Novel, Highly Selective Syk Kinase Inhibitor Significantly Ameliorates the Severity of Arthritis in Rodents
Zhong Cui Sun1, Yu Cai1, Yan Qiu1, Lei Fang1, Xiaoming Dai1, Zhipeng Wu1, Ping Ren1, Jianlin He1, Changwu Lu1, Yongjuan Yu1, Jian Wang1, Yang Sai1, James Yan1, Jia Li1, Wei Deng1, Weihan Zhang1, Jianguo Ji2, Weiguo Su1 and Haoran Zhao1, 1Hutchison Medipharma Limited, Shanghai, China, 2Abott, Shanghai, China
Hutt Hospital
Confirmation of Association of Urate Transporter SLC17A1 (NPT1) with Gout At a Genome-Wide Level of Significance
Tony R. Merriman1, Amanda Phipps-Green1, Murray Cadzow1, Ruth Topless1, Marilyn E. Merriman1, Gregory T. Jones1, Andre M. van Rij1, Nicola Dalbeth2, Peter J. Gow3, Andrew Harrison4, John Highton5, Peter B. B. Jones6, Lisa K. Stamp7 and Jade E. Hollis-Moffatt1, 1University of Otago, Dunedin, New Zealand, 2University of Auckland, Auckland, New Zealand, 3Middlemore Hospital, Auckland, New Zealand, 4Hutt Hospital, Lower Hutt, New Zealand, 5Univ of Otago Med Sch, Dunedin, New Zealand, 6Waikato Clinical School, Waikato Hospital, Hamilton, New Zealand, 7University of Otago, Christchurch, Christchurch, New Zealand

Association with Gout of PDZK1 Variants That Influence Metabolic Traits and Serum Urate Levels
Tony R. Merriman1, Nicola Dalbeth2, Jade E. Hollis-Moffatt1, Amanda Phipps-Green1, Ruth Topless1, Marilyn E. Merriman1, Peter J. Gow3, Andrew Harrison4, John Highton5, Peter B. B. Jones6, Lisa K. Stamp7 and Sara Altaf1, 1University of Otago, Dunedin, New Zealand, 2University of Auckland, Auckland, New Zealand, 3Middlemore Hospital, Auckland, New Zealand, 4Hutt Hospital, Lower Hutt, New Zealand, 5Univ of Otago Med Sch, Dunedin, New Zealand, 6Waikato Clinical School, Waikato Hospital, Hamilton, New Zealand, 7University of Otago, Christchurch, Christchurch, New Zealand

Association Between Sugar-Sweetened Beverage Consumption and Gout in the New Zealand Population
Tony R. Merriman1, Nicola Dalbeth2, Lisa K. Stamp3, Marilyn E. Merriman1, Ruth Topless1, Peter J. Gow4, Andrew Harrison5, John Highton6, Peter B. B. Jones7 and Caitlin Glue1, 1University of Otago, Dunedin, New Zealand, 2University of Auckland, Auckland, New Zealand, 3University of Otago, Christchurch, Christchurch, New Zealand, 4Middlemore Hospital, Auckland, New Zealand, 5Hutt Hospital, Lower Hutt, New Zealand, 6Univ of Otago Med Sch, Dunedin, New Zealand, 7Waikato Clinical School, Waikato Hospital, Hamilton, New Zealand
Hvidovre Hospital
The Analysis of Denosumab Discontinuation and Associated Fracture Incidence in the FREEDOM Trial
Jacques P. Brown1, Jens-Erik Beck Jensen2, Chris Recknor3, Christian Roux4, Ove Tørring5, Matt Austin6, Andrea Wang6, Andreas Grauer6 and Rachel B. Wagman6, 1CHUQ-CHUL Research Centre, Laval University, Quebec City, QC, 2Hvidovre Hospital, Hvidovre, Denmark, 3United Osteoporosis Centers, Gainesville, GA, 4Paris Descartes University, Paris, France, 5Institution for Clinical Science and Education Södersjukhuset Karolinska Institutet, Stockholm, Sweden, 6Amgen Inc., Thousand Oaks, CA
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